Parkinsons Recovery was founded in 2004 by Robert Rodgers, PhD to provide support, information and resources to persons who currently experience the symptoms of Parkinson's disease.
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MEDCast is a healthcare program brought to you by http://HCPLive.com that features leading medical experts who discuss a range topic within a particular condition or medical disorder.
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Exploring all things genetics. Dr Patrick Short, University of Cambridge alumnus and CEO of Sano Genetics, analyses the science, interviews the experts, and discusses the latest findings and breakthroughs in genetic research. To find out more about Sano Genetics and its mission to accelerate the future of precision medicine visit: www.sanogenetics.com
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Life At Optimal with Dr. John Bartemus
Dr. John Bartemus; sharing the latest research and clinical findings in Functional Medicine and Chiropractic to help you achieve and maintain optimal health and wellness via fitness, nutrition, weight loss, and more.
Dr. John Bartemus will share the latest research and clinical findings in Functional Medicine and Chiropractic to help you achieve and maintain optimal health and wellness. Do you suffer from thyroid problems, adrenal fatigue, leaky gut, dysbiosis, hormone imbalance, trouble with weight loss, or any of the host of common chronic diseases plaguing the developed world? Then this is your hub for information on how to take back your health naturally.
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EP 143: Harnessing human data in drug development with Jakob Steinfeldt, Co-Founder and Chief Scientific Officer at Pheiron
36:17
36:17
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Jakob and background on Pheiron 02:14 What made Jakob decide to start Pheiron, what the company does, and how his scientific background inspired him to found a start-up 5:24 Jakob’s excitement and inspiration around the power and potential of machine learning 07:07 Cardiology and heart failure as …
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EP 142: From genome to bedside: How genetics is transforming modern medical practice with Dr. Andrea Gropman
42:45
42:45
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0:00 Introduction 1:40 Andrea’s background and how she got into the field of genetics, neuroimaging, and metabolic disorders 4:00 Insights into Andrea’s clinical practice, including the diverse families and patients she serves and her approach to clinical decision-making 6:30 How genetics and genomics have changed the diagnostic journey in the last…
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Below are the questions I asked Jaroslov Boublik PhD, one of the researchers who formulated the Aquas, about hydrating the body. Why can’t we become better hydrated by simply drinking more water?Why do we become more dehydrated as we age?Why is a well hydrated body essential to eliminating toxins from the body?How do the following affect hydration?…
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EP 141: Bringing genomics to the clinic with Lori Orlando, Associate Prof at Duke University
43:24
43:24
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0:00 Intro to The Genetics Podcast 01:00 Welcome to Lori Orlando 03:00 Lori’s career: From mathematical modelling to genetics and family history 05:11 The study that revealed 20% of the general population is at a higher risk of disease than average and needs preventative care 07:36 The first five diseases that Lori started analysing through informa…
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Integrating Dry Eye Care Within Ophthalmic Surgery Practice
31:06
31:06
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Experts discuss strategies for making dry eye care an appealing practice option for optometry students and supporting their success in this specialized field.By MJH Life Sciences
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1
Addressing Suboptimal Anti-VEGF Response in Neovascular AMD and DME
20:50
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A panel of ophthalmologists discuss strategies for managing AMD and DME patients who exhibit suboptimal responses to their current anti-VEGF therapy.By MJH Life Sciences
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EP 140: The future of Electronic Health Records and data analysis with Ben Goldacre
52:51
52:51
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0:00 Intro to The Genetics Podcast 1:00 Welcome to Ben Goldacre 02:22 Ben’s open data projects at the Bennett Institute and the challenges they aim to tackle 04:03 Using Electronic Health Records (EHR) to help the National Health Service improve care 06:18 The importance of software development within healthcare data and how to manage salary scales…
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1
Beyond the Surface: Monitoring your Patients with Moderate to Severe Plaque Psoriasis
40:43
40:43
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A panel of dermatologists have a comprehensive discussion on exciting developments in the treatment of plaque psoriasis, focusing on treatment approaches, patient monitoring strategies, and recent clinical trial data.By MJH Life Sciences
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Key Considerations for the Effective Utilization of RSV Vaccines
45:25
45:25
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Experts give important background information on respiratory syncytial virus (RSV), as well as the key clinical considerations that are associated with RSV vaccine use.By MJH Life Sciences
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EP 139: Rare disease breakthroughs using tRNA with Michelle Werner, CEO of Alltrna and CEO-Partner of Flagship Pioneering
44:42
44:42
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0:00 Intro to The Genetics Podcast. 01:00 Welcome to Michelle. 02:00 Sstop codon diseases and how are they characterised 03:45 Diseases caused by premature stop codons in haploinsufficient genes. 04:35 The role of transfer RNA technology in finding solutions for premature stop codon diseases. 06:16 How Alltrna is engineering tRNAs which can bind to…
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EP 138: Personalised medicine using microbiome models with Dr. Almut Heinken
40:22
40:22
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0:00 Introduction 1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple…
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1
Generational Trends and Innovations in Retinal Disease Care
22:36
22:36
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A panel of ophthalmologists discuss how retinal disease management has evolved in the past decade and continues to change with advancements in diagnostics and therapies.By MJH Life Sciences
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1
Fostering Next-Generation Expertise in Dry Eye Treatment
36:49
36:49
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Experts discuss strategies for making dry eye care an appealing practice option for optometry students and supporting their success in this specialized field.By MJH Life Sciences
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EP 137: Mavis Machirori on promoting equity, diversity, and social justice in genomics research
41:40
41:40
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0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…
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EP 136: Developments in ring chromosome 20 research and advocacy with Allison Watson
40:57
40:57
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0:00 Introduction 2:00 Allison’s personal journey to researching epilepsy and ring chromosome 20 syndrome 4:00 Biggest challenges families face with ring chromosome 20 syndrome 11:00 Incidence and prevalence of r(20) syndrome, and how we can improve data reliability 21:00 Applying next generation sequencing to r(20) syndrome gene research 29:00 Eng…
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EP 135: Integration of newborn sequencing programs into healthcare systems with Dr. Ingrid Holm
41:16
41:16
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0:00 Introduction 1:30 Ingrid’s initial interests in genetics, paediatrics, and newborn screening 2:45 How the original BabySeq project, a pioneering newborn sequencing program got started, how it’s going, and the launch of BabySeq2 8:45 Lessons from BabySeq1 and goals for BabySeq2 10:30 Potential societal and long-term considerations for those inv…
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1
Focusing in on Novel Oral Systemic Therapies for Moderate Plaque Psoriasis
39:05
39:05
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Medical experts discuss developments in the treatment landscape of moderate plaque psoriasis, including a novel oral systemic treatment which provides an opportunity to alleviate disease burden.By MJH Life Sciences
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EP 134: Prenatal genetic testing and the future of AI in genetic counselling with Kira Dineen, host of DNA Today
40:44
40:44
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0:00 Introduction 1:00 The backstory of how Kira first started DNA Today in 2012, when she was still in high school! 3:30 Some of Kira’s favourite topics she has discussed on DNA Today, including the legacy of Henrietta Lacks, and the story of a Glee actress with down syndrome 10:00 Kira’s best practices for podcasting, from over 10 years of experi…
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1
Magnesium - The Missing Link to Total Health
52:00
52:00
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Promoting a positive message of health, vitality, and well-being, Magnesium – The Missing Link to Total Health (Revised)® provides evidence-based scientific research on magnesium's role in human health. Website: https://drcarolyndean.com/By Parkinsons Recovery
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1
Exploring Procedural Treatments for Dry Eye
41:53
41:53
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Experts discuss treating dry eye with procedural therapies, focusing on common in-office and at-home treatments.By MJH Life Sciences
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EP 133: Insights into pharmacogenomics and increasing diversity in genomics research with Dr. Emma Magavern
39:17
39:17
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0:00 Introduction 2:00 The value of an English Literature degree in designing and analysing research studies in medicine 3:45 Emma’s entrance to pharmacogenomics and her transition from practising physician to genetics research 6:00 How the East London Genes and Health program is increasing representation of diverse populations, namely South Asians…
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EP 132: From mammoths to genome editing, trailblazing genetics with Dr. George Church
47:41
47:41
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0:00 Introduction 1:00 George’s upcoming big projects, including developing full recycling, renewing energy, creating bioweather maps, and harnessing citizen science 6:45 Progress in engineering viral resistance in humans, including thoughts from pre- and post- pandemic 11:00 A swapped genetic code that prevents viral infections and gene transfer b…
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Comparing a Mental Illness Recovery with Parkinsons
50:00
50:00
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Alice A. Holstein, Ed.D was diagnosed with bipolar mood disorder at the age of 51, which interrupted her career and produced some 12 years of intense suffering with many manic episodes, many hospitalizations, thousands of dollars spent and overall, a bleak prognosis of recovery. She lives now, as an elder, with a full if careful life of extraordina…
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EP 131: The potential of somatic genomics in drug discovery and development with Jake Rubens
44:57
44:57
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0:00 Intro 0:40 Jake’s experiences as a serial entrepreneur starting five companies with a basis in genomic science 5:30 Opportunities for research and drug development in the realm of somatic science 9:20 Somatic evolution and how it provides valuable insights into disease mechanisms 12:30 Advantages and disadvantages of studying germline genome-w…
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EP 130: Quarterly insights into noncoding variants and GWAS with Dr. Veera Rajagopal
51:56
51:56
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Show Notes: 0:00 Introduction 1:20 How polydactyl mutations can inform research on non-coding variant mechanisms The importance of low-affinity binding between transcription factors and targets How these lessons can help us improve our understanding of drug and target discovery See Veera’s January round-up for more information: https://www.gwasstor…
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Dyskinesia: Importance of Giving Patients More Good “On- Time" in Parkinson’s Disease
34:54
34:54
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Drs Isaacson, Pahwa, and Gupta discuss the management of dyskinesia and providing good ON time in Parkinson’s disease, sharing practical tips for early identification and treatment of dyskinesia, as well as their experience with current treatments.By MJH Life Sciences
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1
Treating Dry Eye in the Presence of Ocular Comorbidities
40:48
40:48
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Experts discuss the management of dry eye in the presence of concurrent ocular conditions, as well as managing dry eye before undergoing cataract and refractive surgery.By MJH Life Sciences
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EP 129: Patient advocacy for genetic ALS and FTD with Jean Swidler, Executive Director of End the Legacy
38:44
38:44
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0:00 Introduction 0:45 Jean’s personal experiences with family members with genetic ALS 10:00 Jean’s thoughts on the barriers and facilitators to providing treatment for those with genetic ALS 13:20 Insights into C9orf72, a common genetic determinant of ALS, and how it can also be associated with FTD 16:10 Jean’s experiences as an active advocate f…
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EP 128: Parkinson’s disease and precision medicine with Drs. James Beck and Ignacio Mata
50:18
50:18
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0:00 Introduction 1:05 Insights into the PD GENEration’s (a programme from the Parkinson's Foundation) milestones and progress points for the upcoming year 3:30 The shifting attitudes and perspectives of neurologists and healthcare workers at the PD GENEration 5:50 Insights into Nacho’s work with the genetics of Parkinson’s disease 10:20 Barriers a…
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EP 127: Insights into precision medicine, fatty liver disease, and minimally invasive diagnostic tools with Dr. Mazen Noureddin
39:10
39:10
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0:00 Intro 0:25 Mazen’s lifelong commitment to furthering the field of precision medicine in liver disease research, fueled by a personal connection of his grandmother developing MASH cirrhosis 2:30 Breakthroughs in the field of metabolic dysfunction-associated steatotic liver disease (MASLD) since the beginning of Mazen’s career 5:30 The potential…
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Experts discuss the management of dry eye using conventional and new pharmacological treatments, as well as strategies for tailoring treatment approaches to individual patient characteristics.By MJH Life Sciences
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EP 126: Patient-led research for ultra-rare disease drug development with Julia Taravella, Executive Director of Rare Trait Hope Fund
39:41
39:41
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0:00 Introduction 0:25 Julia’s personal experience with ultra-rare diseases within her family 10:25 The importance of increasing accessibility to genetic testing across populations to learn more about ultra-rare diseases 14:00 The origin story of Rare Trait Hope Fund 23:50 Current research and next steps in developing potential gene therapies for a…
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Widening the Therapeutic Window in the Management of Parkinson’s Disease
35:45
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Expert neurologists discuss strategies to widen the therapeutic window of Parkinson’s disease and options available to treat dyskinesia, providing better control of Parkinson’s disease.By MJH Life Sciences
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EP 125: The future of UK Clinical Trial Policy: Innovation, integration, and game-changing legislation with Lord James O’Shaughnessy
45:23
45:23
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0:00 Introduction 1:25 How Lord O’Shaughnessy became involved in scientific policy making and his path to writing the UK Commercial Clinical Trials Review. 04:05 How Lord O’Shaughnessy pivoted from education to a focus on life sciences 06:38 The biggest challenges Lord O’Shaughnessy faced during his time as Parliamentary Under Secretary for Health …
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EP 124: How ReCode Therapeutics is pioneering tissue specific delivery of gene therapies for Primary Ciliary Dyskinesia with John Matthews
42:00
42:00
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0:00 Introduction 01:10 How growing up in Malawi planted the seeds for John’s career in medicine and transition to therapeutic development 04:35 Why John focuses on rare diseases and conditions such as asthma 06:01 What has changed over the last decade in terms of treating and understanding asthma and the progress that genetics has enabled 07:31 Wh…
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A Patient-Centric Medcast on the Journey Through Moderate Plaque Psoriasis
52:36
52:36
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Advanced practice providers in dermatology discuss exciting developments in the treatment landscape of plaque psoriasis. Listen to their insights into the often-challenging journey patients go on. The arrival of novel oral systemic treatment options offers opportunities to alleviate the burden of this chronic disease.…
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EP 123: The ethics of newborn genome screening: Actionable insights and beyond with Holly Peay, Senior Research Scientist at the Research Triangle Institute
45:34
45:34
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0:00 Introduction 0:50 Holly’s background and career so far 03:30 Complex decision-making and multiple risk factors: Family history, genetics, phenotypes and beyond 07:05 Changes within the last decade to help people make complex, sometimes subjective, healthcare decisions 09:20 Impact on people: The RTI’s mission and the Early Check Study 13:45 Ne…
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EP 122: Building genome-scale engineered cells for biotechnology with Leslie Mitchell, Co-founder and CEO of Neochromosome
35:55
35:55
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Summary: 0:00 Introduction 01:01 How Leslie got into the field of synthetic biology and engineering, and her career journey so far 02:45 What Leslie accomplished during her postdoc and recent transformations in the field of genomics 05:57 The impacts of non-coding regions of the genome and the outcome of deletions 08:20 How long it takes to make ch…
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Neurons are cells that contain mitochondria. Photobiomodulation energizes neuronal mitochondria, triggering a cascade of beneficial cellular functions. Potential benefits are neuroprotective effects, self-repair mechanisms and enhanced functionality. Vielight’s patented intranasal stimulation technology and microchip LED technology is an innovative…
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EP 121: Breakthroughs and insights in ALS research with Dr. Michael Benatar
44:10
44:10
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Summary: 0:00 Introduction 0:50 Reflections from the 34th International Symposium on ALS/MND in Basel 1:50 Michael’s professional journey, initial challenges he encountered, and how the field of neurology has evolved over the years 3:10 An introduction to the ALS landscape, including its presentation, the genes involved, and potential treatment opt…
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EP 120: Exploring the frontiers of gene therapy and AAVs with Dr. Nicole Paulk, CEO and Founder of Siren Biotechnology
43:47
43:47
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0:00 Introduction to Dr. Nicole Paulk, a pioneer in AAV research and the founder of Siren Biotechnology 0:50 The moments that shaped Nicole’s career path and her passion for gene therapy and AAV research 9:20 Nicole’s academic research career and her transition from academia to the biotech industry 23:00 The story behind the founding of Siren Biote…
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EP 119: Revolutionising drug discovery: how the Pharma Proteomics Project is combining genetic and proteomic data with Chris Whelan
38:25
38:25
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0:00 Introduction 01:00 Chris’ background and career to date 02:10 What is the Enigma Project? 04:48 How is genetics being applied to drug discovery today and how does proteomics fit in? 09:23 When the UKBiobank Pharma Proteomics Project began and how long it took to set up 10:57 54k UK Biobank participants tested - discussion of findings 14:33 The…
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EP 118: The role of genetics in drug discovery and development with Dr. Matt Nelson
42:56
42:56
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Summary: 0:00 Introduction 5:45 Lessons learned from 15 years at GSK: How has genetics and drug discovery evolved over time? 8:10 Matt’s seminal 2015 paper: Quantifying the impact of human genetic evidence on the probability of success in drug development 11:40 Which types of genetic evidence are the best drivers of success in clinical trials? 13:3…
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Parkinsons Recovery Survey Results: Part 2
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This podcast constitutes a reading of responses to the 2023 annual Parkinsons Recovery survey. As you will discover, people discover a wide range of therapies, methods and practices that offer them opportunities to celebrate symptom relief. Best of all, 73% of resondents reported they were either better or the same since the previous holiday in 202…
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Robert Rodgers PhD provides a summary of the 2023 Parkinsons Recovery Survey in this presentation. Get ready to be surprised and encouraged at the results. Robert Rodgers PhD Founder 2004 Parkinsons Recovery https://www.parkinsonsrecovery.comBy Parkinsons Recovery
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EP 117: Wendy Chung: whole genome newborn screening and other big opportunities in genomic medicine.
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47:51
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Summary: 0:00 Introduction 1:45 Wendy’s early career looking into the genetics of diabetes through mouse models 6:23 A high altitude view: Cutting through hype to spot the next wave of game-changing technology 8:03 The role of policy and communication: how Wendy’s work goes beyond the lab to create real-world impact 11:20 Wendy’s choice to do an MD…
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EP 116: Genetics and Medicine: Clonal hematopoiesis, genomics in healthcare, and a new discovery in APOL1 kidney disease with Dr. Alex Bick
52:34
52:34
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0:00 Introduction 4:23 Insights into clonal hematopoiesis from the pioneering Framingham Heart Study 8:30 Linking clonal hematopoiesis to cancer and cardiovascular health 11:22 Interplay of germline and somatic variants in clonal expansion 17:20 How the rate of clonal expansion can provide insights into cancer and cardiovascular risk 19:00 How clon…
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EP 115: The Biggest Stories of 2023 with Dr. Veera Rajagopal (Part 2)
1:35:11
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In the second instalment of our annual round-up episode, we welcome back Dr. Veera Rajagopal to cover the biggest stories in genetics and precision medicine of the last 12 months. Don’t forget to give the first instalment of our 2023 round-up a listen. Veera is a scientist at Regeneron with an interest in human genetics and drug target discovery in…
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EP 114: The Biggest Stories of 2023 with Dr. Veera Rajagopal (Part 1)
1:10:35
1:10:35
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0:00 Introduction 1:30 Veera’s personal highlights of 2023 Publication in Nature Genetics: Rare coding variants in CHRNB2 reduce the likelihood of smoking, an exome-wide association study identifying rare coding variants in CHRNB2 that may reduce the likelihood of smoking. Designing cover art Genetic links to neural circuits and their role in addic…
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Paradigm Shift in Non-Motor Symptom Management in Parkinson’s Disease
49:14
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The expert neurologists discuss non-motor symptoms of Parkinson’s disease: types, their impact on patient’s quality of life, and current and emerging treatment options for non-motor symptoms.By MJH Life Sciences
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