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Welcome to Signs. (Every Thursday, most likely) A podcast where I talk to you about my life as a journalist/writer and other things. I have a cat named Reggie and sometimes I make him laugh. Keep boomin' babay.
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This is The Recap Round podcast where the boys from @TwoGroovesLow bring you a weekly 30-45 minute podcast about the PGA Tour. It drops every Monday morning and these above average golfers have all the best recap notes and tidbits.
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Why do some of us age gracefully and others don’t? How do our bodies and minds experience aging at the cellular and molecular level? Why do we even age to begin with? And maybe most importantly, can we do anything about it? Join host Gordon Lithgow at the Buck Institute in California as he speaks with some of the brightest scientific stars on the planet to search for – and actually find answers to – these questions and many more.
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What do we really want from our healthcare system, and how can AI help us get it sooner? In our final episode of season two, Gordon talks with visionary systems biology expert Nathan Price about the emergence of scientific wellness, what we can learn from our digital twins, and how using AI to predict health outcomes can help us transform our under…
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Few people have as much experience with patient care and long-term research as the celebrated geriatrician and epidemiologist Luigi Ferrucci. Listen in as he speaks with Gordon about his journey from acute care to population studies, the effective design of clinical trials, and moving towards predictive medicine so we can use our natural resilience…
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The movement to integrate longevity treatments into clinical care is making strides. How can we ensure they are evidence-based, accessible, and personalized? World-renowned geroscientist Andrea Maier has been leading the way with innovative clinical trials and cutting edge research. In this episode, she talks with Gordon about the current state of …
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Our chronological age doesn’t tell us much about how well our bodies are aging, but scientists have developed many ways to measure changes at the cellular and molecular levels, including the rate of change, that can suggest ways to improve health at every stage of life. Follow along as Gordon speaks with Daniel Belsky of Columbia University about D…
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Of all the biochemical changes that occur with aging, what really matters? How can we use the incredible amount of health data available today to discover the best targets for interventions? In this episode, Kristen Fortney of BioAge talks with Gordon about the latest research in proteomics and metabolomics, the importance of muscle loss, and the c…
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What is the relationship between diet, chronic disease, and aging? Can we delay or reverse the effects of aging at the cellular level by following a fasting-mimicking diet? Listen in as Gordon speaks with Valter Longo of the Longevity Institute at USC about epigenetic reprogramming, turning on Yamanaka factors, and restoring our cells to a youthful…
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Our modern world is full of potential disruptions to sleep. But as we learn more about circadian rhythm, we find that it influences everything from metabolism to mental health in different ways as we age. In this episode, Satchin Panda of the Salk Institute guides Gordon through the many interactions between sleep behavior and biology. Together the…
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What is the goal of living longer? It’s not simply to celebrate a number, but to do something meaningful with that time. Renowned Stanford psychologist Laura Carstensen speaks with Gordon about the experience of aging, in the past and in the future, and why changes in culture must accompany changes in healthspan so we can flourish as a society. Lau…
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We're back! In season one, we investigated the biology of aging in many different organisms to learn why and how we age. This season we'll take a close look at potential interventions that modify mechanisms of aging biology and may dramatically change the way we age in our lifetimes. Get ready for season two of the Buck's podcast We're not getting …
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Gordon and Stella revisit key concepts from the conversation with Arne Akbar, such as using sestrins to modulate T-cells and telomeres. Looking back over the course of season one, Stella and Gordon discuss the need to think about aging as an organizing principle, and how to deal with all the things we don't yet know. Stay tuned for season two! Supp…
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What role does the immune system play in aging? How do senescent cells evade it and promote inflammation? And what does it reveal about developing effective interventions? Immunologist Arne Akbar joins Gordon to break down the array of actors and pathways involved, including sestrins, immune memory, the gut microbiome, and more. Along the way, Arne…
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After the conversation with Monica Driscoll, Gordon and show editor Stella connect to discuss the link between cell death and aging, what we can learn from sending worms to space, and the need for personalized medicine in aging interventions. Finally, they look forward to the next episode with immunologist Arne Akbar. Support the Show.…
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How do different cells in our bodies age differently? What exactly happens when a neuron takes out its trash? In this episode, neuroscientist Monica Driscoll takes Gordon on a tour through her serendipitous career. Topics include sloppy developmental biology, enigmatic exophers, worms in space, and the importance of studying things no one else is t…
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Gordon and show editor Stella revisit key concepts from the conversation with Linda Partridge, such as what we can learn from evolutionary biology and how to harness biological processes like autophagy. Looking ahead, they anticipate discussing human clinical trials in the next episode with Nir Barzilai. Support the Show.…
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Aging appears to progress similarly across species, from worms and flies to mice and humans, and involves pathways related to early development. Guest Linda Partridge talks with Gordon while visiting the Buck Institute to discuss the evolutionary trade offs of aging mechanisms, the role of nutrient-sensing pathways, and how we might get the most be…
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What is the relationship between stress, metabolism, and aging? How can we use “good” stress to enhance our ability to weather the challenges of getting older? Guest Rhonda Patrick has investigated the biology of aging and related lifestyle interventions throughout her multifaceted career. In this episode she joins Gordon to explore insights from s…
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Dr. Campisi has been at the forefront of studying cellular senescence for decades, revealing the mysteries of these not-exactly-dead cells and their role in many diseases of aging. In this episode, she joins her colleague Gordon to discuss the characteristics and function of senescent cells, as well as promising interventions on the horizon. Judy a…
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Is life essentially an information process driven by biochemical interactions? If so, can we simply correct any errors in that process? In this episode, renowned researcher and author David Sinclair joins Gordon to dive into the startling insights from applying information theory to aging. Topics include epigenetics, sirtuins, metabolism, and why w…
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When we think of aging, we typically think of human aging, but the biological processes that cause cellular damage are shared by many species. Few people have investigated the biology of aging across the animal kingdom as deeply as researcher and author Steve Austad. In our first episode, Steve and host Gordon Lithgow explore some fundamental quest…
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In the first half of the interview, Pace talks about the latest girls and boys Class B basketball polls. In the second half of the interview, Central Cass (BBB) head coach Matteson Norman joins us to talk about the 2018-19 season as well as why the Squirrels have team meetings at Buffalo Wild Wings. #NDpreps…
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On the third episode of Signs w/ Pace Maier, he talks about why he missed an upload last week. (Sorry about that guys and gals :\ but I'm back!. He also tells a story about the email in his inbox he received two days ago that was from 27 month old thread. SUper weird and creepy. What should he do about it? Let him know @pacetheaceND…
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On the second episode of Signs w/ Pace Maier, he talks about his date and how she could be the next golfer on the horizon. He also talks about how taking your pet to the vet is spendy but also necessary. He ends the podcast talking about how calling your parents once a week isn't a horrible idea. Hope everyone enjoys!…
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On the first episode of Signs w/ Pace Maier, he talks a little bit about his background and why he started the podcast. He also gives a mini preview of what pissed him off this past week. This episode is a shorter one than most will be but he didn't want to bore you to death on the first episode.By Signs w/ Pace Maier
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