Best Professor Declan Murphy Podcasts (2024)

1
2024 EAU Prostate Cancer Guidelines - some big changes!! 47:52

8d ago47:52

47:52

Pelvic lymph node dissection down-graded. Systematic prostate biopsies no longer recommended. More clarity around PSMA PET/CT for staging. Surgery no longer recommended for cN1 prostate cancer. Yep the recent updates to the EAU Prostate Cancer Guidelines had a lot of important changes for the global urology community to digest. So we invited EAU Pr…

1
#APCCC24 Conference Highlights | Part 1 49:26

12d ago49:26

49:26

The first of two Conference Highlight specials from the Advanced Prostate Cancer Consensus Conference, held in April 2024 in Lugano. This is our very favourite prostate cancer meeting and we are thrilled to bring you these highlight podcasts. In this epsiode we chat with Silke Gillessen, Derya Tilki, Jochen Walz, Neha Vapiwala, Dingwei Ye, and the …

1
GU Highlights at #ASCO24 | with Marty Schoen 35:00

19d ago35:00

35:00

Didn't get to ASCO this year?? Us neither!! But not to worry, we checked in with Dr Marty Schoen who did, and brings us all the key highlights! Marty is a GU Medical Oncologist at the St Louis Veterans Affairs Medical Centre and the University of St Louis, Missouri. He runs through a smattering of stuff that caught his eye at ASCO this year. Thanks…

1
Pembro improves survival after nephrectomy | Huge news for Urologists 45:57

25d ago45:57

45:57

For Urologists, there are not that many papers that come along where we can say - "this will almost immediately change my practice". But KEYNOTE-564 looks like one of those! A large phase III randomised trial of adjuvant pembro following nephrectomy for renal cell carcinoma in patients deemed at higher risk for recurrence. Regular listeners/viewers…

1
En-bloc party! RCT of TURBT with Jeremy Teoh 29:46

30d ago29:46

29:46

Should we remove bladder cancers piece-meal by chopping them into little pieces, or should we try and remove en bloc with a margin around the base?? This very nice randomised controlled trial from our friends in Hong Kong demonstrates that the recurrence rate is significantly lower if we use the all-too-rarely used en bloc technique. Dr Jeremy Teoh…

1
Three big challenges in metastatic prostate cancer | Dr Alicia Morgans 38:04

1M ago38:04

38:04

Today we have Dr Alicia Morgans, GU Medical Oncologist and Director of Survivorship at Dana Farber Cancer Institute, in the GU Cast studio for a chat. We wanted to ask Alicia to look forward and identify three big challenges we will face in metastatic prostate cancer over the next 5-10 years. What did we come up with??!! Tune in to find out!! Even …

1
Metastatic prostate cancer in China today 40:48

2M ago40:48

40:48

In the first of our special episodes focussing on GU Oncology in China, we are delighted to welcome our inaugural GU Cast China Editor. Professor Yao Zhu, to the GU Cast studio. Yao is a Urologist at Fudan University Shanghai Cancer Centre, and is well known to all of us at GU Cast and Peter MacCallum Cancer Centre. As part of our Gold Partnership …

1
Uro-Podcasters Love-in in Lugano!! 16:50

2M ago16:50

16:50

Great fun on the shores of Lake Lugano where the hosts of three of the best -known podcasts in GU Oncology get together for a chat! Declan and Renu from GU Cast, join with Brian and Tom from Uromigos, and Gill from Oncoalert. How did it all start? Why did it all start?! Best moments, worst moments etc. Tune if for a chat, and do please subscribe/li…

1
ProsTIC24 PSMA Theranostics Conference Highlights 47:21

2M ago47:21

47:21

The 2nd ProsTIC Preceptorship is one of the most intense fora for the discussion of PSMA theranostics anywhere in the world! A biennial meeting in Melbourne with many of the world's leading experts in the field. Not just superb practical advice about how to get your prostate cancer theranostics program to the next level, but some amazing discussion…

1
Proton therapy no better than standard prostate radiotherapy 29:57

3M ago29:57

29:57

A new paper in the Journal of Clinical Oncology is reporting that the bowel and urinary side-effects of proton therapy (a high tech and very expensive type of radiotherapy), are no better than side-effects after standard high-quality radiotherapy (called IMRT). Quite a fuss on twitter when this paper came on line last week including from a fair few…

1
ADT and cardiac risks (and how I sold my company for $1.4bn) 32:03

3M ago32:03

32:03

Professor Neil Fleshner (University of Toronto) drops into the GU Cast studio in Melbourne for an intriguing discussion! First we cover off the underrated topic of cardiac risks in patients starting androgen deprivation therapy and how we can reduce these for the benefit of our patients. Then we talk to Neil about entrepreneurship and his journey i…

1
Happy days for metastatic bladder cancer | Enrique Grande and Andrew Weickhardt 32:23

3M ago32:23

32:23

A big medical oncology love-in in the GU Cast studio today!! Professor Enrique Grande was visiting from MD Anderson Cancer Centre in Madrid to chat all about some of the sensational advances we have seen in metastatic bladder cancer in recent times. And we were also joined by old friend Professor Andrew Weickhardt from Austin Health in Melbourne to…

1
High risk prostate cancer and mHSPC | With Axel Merseburger 26:48

3M ago26:48

26:48

Axel Merseburger (Chief and Professor of Urology, Lubeck, Germany) was in Australia recently and popped into the GU Cast studio for a chat. Axel was at the USANZ ASM recently and also on a speaker tour supported by Janssen Pharmaceuticals, so we put together this Themed Podcast to pick his brains on high-risk prostate cancer and mHSPC in 2024. This…

1
#USANZ24 Conference Highlights 59:47

4M ago59:47

59:47

Declan and Renu bring you lots of highlights and interviews from the Urological Society of Australia & New Zealand (USANZ) Annual Scientific Meeting (ASM) which took place last week in Adelaide. Almost 1000 delegates descended on this beautiful part of the world, famous for its beaches and wineries. Hear from Robert Nam, Paul Anderson, Nathan Lawre…

1
What does a randomised trial tell us about prostate biopsy? 32:22

4M ago32:22

32:22

Needle through the rectum or needle through the skin?? Transrectal vs transperienal prostate biopsy is certainly a hot topic in prostate cancer, with the vast majority of men having their biopsy through the rectum rather than through the skin. It is quick, cheap and easy (for the urologist and the health system), but leaves the patient at risk of s…

1
"Unethical trials", or so says Vinay! 49:34

4M ago49:34

49:34

Two of the highest profile presentations at the recent ASCO GU Meeting were the plenary presentations of the CONTACT 02 trial, and the Keynote-564 trial. Generally speaking, these were well received; indeed quite enthusiastically received in some quarters! Not however in the quarter of prolific oncology commentator and Haematologist/Oncologist & Pr…

1
Renu's ASCO GU Highlights 54:46

4M ago54:46

54:46

Renu caught up with lots of experts and friends at ASCO GU in San Francisco recently and brings you all the highlights. Hear from Toni Choueiri, Matt Cooperberg (on that debate on renaming low-grade prostate cancer), Todd Morgan, Neha Vapiwala, Morgan Roupret, Sophia Kamran, Morgan Roupret, Sam Washington, plus a great chat with Tyler Seibert while…

1
Bringing LuPSMA earlier | ProsTIC/PCF/ICIS Global Webinar 1:23:00

5M ago1:23:00

1:23:00

For all you enthusiasts of PSMA theranostics, we bring you another one of our fabulous ProsTIC/Prostate Cancer Foundation Global Webinars with some of the best minds in the business. This is the eighth of our collaborative webinars over the past four years and the focus today is bringing lutetium PSMA earlier in prostate cancer. Two keynote lecture…

1
A Touchy Subject | With Victoria Cullen 44:12

5M ago44:12

44:12

A must listen (actually a must WATCH!!) episode of GU Cast if you have any experience with the side-effects of treatment of prostate cancer. Whether you are a patient or loved one, or a surgeon/radiation oncologist/medical oncologist, or a nurse or allied health professional - then this is for you. Declan and Renu chat about "A Touchy Subject" with…

1
APCCC Travel Award Winners Revealed!! 3:11

5M ago3:11

3:11

We reveal the three winners of our APCCC Travel Awards 2024! These three trainees will be heading off to Lugano for the world's best prostate cancer meeting which takes place from 25-27 April on the shores of Lake Lugano.By Professor Declan Murphy & Dr Renu Eapen

1
Reducing "useless" lymph node dissections with PSMA 45:11

6M ago45:11

45:11

By Professor Declan Murphy & Dr Renu Eapen

1
Last few days to enter our great APCCC Lugano giveaway!!! 1:24

6M ago1:24

1:24

A quick message from Renu and Declan about our huge travel award giveaway to start the new year! Closing date Monday 15th Jan 2024 Full details on https://www.gucast.org/By Professor Declan Murphy & Dr Renu Eapen

1
Toni's Top 10 GU Oncology Papers 2023!! 39:44

6M ago39:44

39:44

A truly great Christmas tradition is when Toni Choueiri and his merry band of GU Oncology Fellows at Dana Farber, drop their list of the Top 10 GU Oncology papers of the year. And true to form, Toni's tweet on Christmas Day contains an immaculate list of GU highlights of 2023. A great mixture of tumour types, some brave choices with a Phase 1 study…

1
Christmas Special | Plus our big APCCC Giveaway! 34:12

6M ago34:12

34:12

Our final podcast of 2023 and it's a big one!! Huge festive giveaway with three fully funded GU Cast travel awards to attend the APCCC in Lugano (April 2024) up for grabs. Alastair Lamb zooms in from Oxford to discuss prostate cancer spatial transcriptomics. Kiaran O'Malley (Mater Hospital, Dublin) drops into studio for a festive drink, and GU Cast…

1
Lymph node dissection!! In GU Oncology 32:01

7M ago32:01

32:01

Dr Ashish Kamat (MD Anderson Cancer Centre, Houston), joins Declan and Renu to discuss a very nice paper recently published in European Urology Oncology overviewsing the role of lymph node dissection (LND) in GU oncology. Really nice piece of work led by Dr Amanda Myers along with a bunch of well known names in urologic oncology. A very succinct su…

1
ARPIs for dummies! Plus the Jiffy Stent 34:16

7M ago34:16

34:16

It has becoming a familiar refrain around the world , and is certainly good news for the prostate cancer community! This week, another androgen receptor pathway inhibitor (ARPI) became reimbursed for men with hormone-sensitive metastatic prostate cancer (mHSPC) in Australia. Darolutamide is already available for men with non-metastatic castration-r…

1
Lymph node recurrence - what to do and when??! With Piet Ost, Shankar Siva and Michael Hofman 30:11

7M ago30:11

30:11

SABR supremos Piet Ost and Shankar Siva join us to discuss the management of lymph node-only recurrence following primary treatment of prostate cancer. And of course our resident PSMA PET/CT guru Michael Hofman also turned up as himself and Piet love debating the merits of PSMA! How and when shoudl we image for biochemical recurrence? What are the …

1
nmCRPC made easy!! Who, when and how 37:25

7M ago37:25

37:25

Prof Fred Saad (University of Montreal) drops in to chat about the interesting condition that is non-metastatic castration-resistant prostate cancer (nmCRPC). Which men are at risk of developing metastases? When should we use an AR pathway inhibitor? Why PSMA PET/CT should NOT be used. And hear his thoughts on "dabbling" in prostate cancer! Also jo…

1
Big prostate cancer highlights from #ESMO23 38:07

8M ago38:07

38:07

What a great ESMO for GU Oncology!! Declan caught up with some plenary speakers in Madrid to discuss the biggest topics. PSMA theranostics with Louise Emmett (ENZA-P) and Oliver Sartor (PSMAfore); ARPIs in biochemical recurrence with Steve Freedland (EMBARK), Morgan Roupret and Boris Hadaschik. Plus the latest negative immunotherapy trials in prost…

1
LuTectomy in European Urology 44:50

8M ago44:50

44:50

The LuTectomy trial has just been published in European Urology, and as the GU Cast team have been very much involved, we thought we should dive into the details on today's podcast. LuTectomy is a clinical trial to evaluate the role of 177-Lutetium-PSMA prior to radical prostatectomy. Declan is the study co-PI along with Professor Michael Hofman, a…

1
More Shark Patting | With Tim Baker 48:26

8M ago48:26

48:26

One of our most popular episodes in 2022 was "Patting the Hormone Therapy Shark" with author, surfer and prostate cancer survivor, Tim Baker. And a lot has happened in the 12 months since so we invited Tim back for a follow-up chat in this Themed Podcast supported by our GU Cast Gold Partners, Mundipharma. Tim's inspiring approach to managing the s…

1
Three big questions in high-risk prostate cancer | With Boris and Tyler 50:01

9M ago50:01

50:01

We hijacked our good friends Professor Boris Hadaschik (Urologist, Essen, Germany), and Associate Professor Tyler Seibert (Radiation Oncologist, University of California, San Diego), who happened to be in Melbourne this week, and diverted them into the GU Cast studio for a chat about high-risk prostate cancer. Boris and Tyler were on a speaker tour…

1
Going Nuclear at EANM in Vienna 28:37

9M ago28:37

28:37

The European Association of Nuclear Medicine (EANM) Annual Meeting is the World's leading nuclear medicine extravaganza! Today we cross live to Professor Michael Hofman and friends to hear some of the GU highlights at this year's annual meeting in Vienna. Michael is joined by Prof Ken Herrmann, Dr Kerry Jewell, Dr Francesco Ceci, Dr Phiilip Kuo, Dr…

1
Are female surgeons better than men??! 41:51

10M ago41:51

41:51

The mass media were quick to pick up on two papers in JAMA Surgery last week with headlines such as "Patients have better outcomes with female surgeons", and "Should you pick the sex of your surgeon?". So what's it all about?? We chat with lead author of one of these papers. Dr Chris Wallis, Urologist at the University of Toronto, whose looked at o…

1
Let's skip PSA testing! And go straight to an MRI scan... 32:08

10M ago32:08

32:08

Is this the solution to screening for prostate cancer?? Don't bother with a PSA test and instead screen using a 10 minute MRI scan??! Re-IMAGINE is a very interesting prospective study published in BMJ Oncology this week which did exactly that with some really interesting findings. We are joined by study authors Professor Caroline Moore and Profess…

1
Spacing the Rectum! With Peter Orio & Shankar Siva 25:13

10M ago25:13

25:13

What is a rectal spacer and do they help reduce side-effects from prostate radiation??! That's today's topic on GU Cast. Renu caught up with rectal spacer enthusiasts Professor Peter Orio (Dana Farber Cancer Institute) and Associate Professor Shankar Siva (Peter MacCallum Cancer Centre) in downtown Melbourne this week to learn all about this topic.…

1
The European Urology Podcast is coming soon!! 3:32

11M ago3:32

3:32

Here's a quick plug for another podcast that GU Cast is very happy to support! Launching in September 2023, the European Urology Podcast is a new monthly podcast to accompany the world's highest ranked urology journal, European Urology. Co-hosted by Professor Declan Murphy in Melbourne and Dr Joyce Baard in Amsterdam, the European Urology Podcast w…

1
Shiny Happy Editors talk Impact Factors 42:05

11M ago42:05

42:05

Major scientific journals only change their Editor-in-Chief every 8-10 years so it's quite a big deal when it happens! Today we chat with Professor Alberto Briganti, incoming Editor-in-Chief of European Urology, the world's highest ranked urology journal, and with Professor Morgan Roupret, incoming Editor-in-Chief of European Urology Oncology. Why …

1
GU Cast hosts do battle at ANZUP ASM!! 57:01

11M ago57:01

57:01

By Professor Declan Murphy & Dr Renu Eapen

1
Remembering Christchurch | A GU Cast Special 1:03:51

11M ago1:03:51

1:03:51

This, our 100th episode, is a very special GU Cast, in which we remember the devastating 2011 Christchurch earthquake, which hit just as the Urological Society of Australia & New Zealand (USANZ) Annual Scientific Meeting (ASM) was kicking off in the city. 185 people lost their lives with many thousands injured, and with huge devastation across the …

1
Alpha PSMA & New Targets in Prostate Cancer | ProsTIC/PCF Global Webinar 1:28:53

11M ago1:28:53

1:28:53

This is for hardcore PSMA aficionados!! This is the 7th of our ProsTIC/Prostate Cancer Foundation Global Webinars focussing on all things PSMA theranostics (you can find the rest in our back catalogue stretching back to April 2020). We peek into theranostics beyond what we currently have with beta-emitters like LuPSMA, into the tantalising world of…

1
Avoiding cystectomy for high-grade bladder cancer 35:31

12M ago35:31

35:31

Dr Sima Porten from the University of California San Francisco (UCSF), was in Melbourne this week for the ANZUP Annual Scientific Meeting (more from that in an upcoming episode), so she popped into the GU Cast studio to chat with Renu and Declan. Renu of course spent a year with Sima and colleagues doing Fellowship training in GU Oncology so she wa…

1
Bladder cancer bonanza | With Dr Sia Daneshmand 36:21

1y ago36:21

36:21

Two cracking bladder cancer studies to discuss on GU Cast today (in our brand new GU Cast studio)! We are joined by Dr Sia Daneshmand, Urologist and Director of Urologic Oncology at the University of Southern California, who presented the headline-making Tar-200/SunRIse-1 study at the recent Annual Meeting of the American Urological Association. No…

1
Is SABR the best way to radiate the prostate??! 30:10

1y ago30:10

30:10

Stereotactic Ablative Body Radiotherapy (SABR) has been a great tool for managing low volume metastatic prostate cancer for a few years now. One or two visits to the radiation centre, highly targeted, minimal side-effects. So could it be used to treat the primary prostate cancer itself with similar success? Today we have top SABR experts Dr Alison …

1
ARPIs reimbursed for mHSPC | Urologists take note! 35:40

1y ago35:40

35:40

With approvals and reimbursement increasing all the time for the use of AR pathway inhibitors (ARPIs) in metastatic hormone-sensitive prostate cancer (mHSPC), we chat today about how front-line clinicians need to make sure we are making the most of these opportunities for our patients. Urologists in particular are the clinicians who most frequently…

1
ChatGPT - This is nuts!! AI goes mainstream 39:13

1+ y ago39:13

39:13

So if you haven't seen all the fuss about ChatGPT on social media in the past two weeks, then imagine this. You have to write a 500 word introduction to an article on adjuvant therapy following renal cancer surgery, you are a week past deadline and you have writer's block. Or it's your thankless task to organise next year's on-call roster for your …

1
The PCF Retreat 2022 | Highlights from Carlsbad 50:04

1+ y ago50:04

50:04

The annual Prostate Cancer Foundation (PCF) Retreat is in its 29th year, and is the showpiece event of the PCF's incredible research program. Each year, PCF investigators from around the world gather in California to share their work and interact together. Fair to say it has developed a legendary status among the prostate cancer community across th…

1
Gleason 6 prostate cancer | Why we should rename it (and why we can't)! 37:08

1+ y ago37:08

37:08

Is grade group 1 (Gleason 6 in old money) really prostate cancer? Wouldn't life be a little easier for patients (and the rest of the world) if we could somehow remove the label "cancer" from this relatively indolent condition?? Well this decade-old discussion seems to have developed a lot of momentum in the past year, driven by urologists like Dr S…

1
Let's Visit Ireland! The Irish Society of Urology Annual Meeting 33:21

1+ y ago33:21

33:21

A GU Cast Ireland Special! Declan recently travelled to the Annual Meeting of the Irish Society of Urology and posted this GU cast special from Killashee House in County Kildare. Apologies in advance for him wallowing in his Irishness! Declan catches up with Urologists David Bouchier-Hayes, Eva Bolton, Catherine Dowling, and Richie Power, to chat a…

1
Patting the Hormone Therapy Shark | with Tim Baker 49:28

1+ y ago49:28

49:28

OK this episode of GU Cast is essential listening for anyone who has anything to do with androgen deprivation therapy (ADT), or "hormone therapy", for men with advanced prostate cancer. Whether you are a prescriber (especially if you are a prescriber), nurse or allied health professional, patient, loved one, industry representative, or researcher -…

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Professor Declan Murphy Podcasts

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