show episodes
 
Biotech—it's complicated. A successful product launch requires grit, determination, and clear direction. But let’s be real, the path to launch isn’t a straight one. There are curves, hard turns, and dead ends. Here’s the good news, you don’t have to navigate the complexities alone. Welcome to The Emerging Biotech Leader, where we help biotech leaders maximize the value of their therapeutics from clinical development to product launch.
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The Future of Identity podcast talks to the people building the IDtech products of tomorrow. In each episode, Trinsic CEO Riley Hughes dives deep with founders and product builders to discuss their insights about what it takes to successfully launch an identity product. We hope you join us as we highlight the people at the forefront of making IDtech consumable for every day users and what is needed to reach mass adoption.As a leader in the self-sovereign identity movement, Trinsic has seen h ...
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We have more than 30 years of experience helping individuals and businesses who owe taxes to the IRS/State through personalized solutions. We serve to PROTECT their income and assets from the IRS. We resolve taxpayers' tax problems, wage/bank levy, as well as tax liens on your house. We negotiate with the IRS to substantially reduce the tax amount owed if you qualify. Everybody deserves an opportunity to start over and get their happy life back. We will help you get your life back, free from ...
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show series
 
In this emergency episode of The Cognitive Revolution, Nathan discusses alarming findings about AI deception with Alexander Meinke from Apollo Research. They explore Apollo's groundbreaking 70-page report on "Frontier Models Are Capable of In-Context Scheming," revealing how advanced AI systems like OpenAI's O1 can engage in deceptive behaviors. Jo…
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In this episode of The Cognitive Revolution, Nathan interviews Andrew White, Professor of Chemical Engineering at the University of Rochester and Head of Science at Future House. We explore groundbreaking AI systems for scientific discovery, including PaperQA and Aviary, and discuss how large language models are transforming research. Join us for a…
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In this episode of The Future of Identity Podcast, I’m joined by Ajay Gupta, Chief Digital Transformation Officer of the California Department of Motor Vehicles, to discuss California’s groundbreaking mobile driver’s license (mDL) program. From its launch to current adoption trends and future ambitions, this episode provides a comprehensive look at…
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In this episode of The Cognitive Revolution, Nathan welcomes back Div Garg, Co-Founder and CEO of MultiOn, for his third appearance to discuss the evolving landscape of AI agents. We explore how agent development has shifted from open-ended frameworks to intelligent workflows, MultiOn's unique approach to agent development, and their journey toward…
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When does a biotech need a Chief Medical Officer? "If you're asking, you probably needed one yesterday," suggests Dr. Benit Maru in this straight-talking episode of Emerging Biotech Leader. The SSI Strategy medical lead breaks from convention, arguing that early-stage organizations - particularly those in rare disease or novel modalities - can't af…
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In this episode of The Cognitive Revolution, Nathan explores groundbreaking perspectives on AI alignment with MIT PhD student Tan Zhi Xuan. We dive deep into Xuan's critique of preference-based AI alignment and their innovative proposal for role-based AI systems guided by social consensus. The conversation extends into their fascinating work on how…
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In this episode of The Cognitive Revolution, Nathan explores the complex intersection of AI development and international relations with Robert Wright, publisher of the Nonzero Newsletter. They examine the growing militarization of AI, US-China relations, and the concerning trajectory of what Wright calls "the chip war." Drawing from Nathan's recen…
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Nathan explores the world of AI-powered design with John Milinovich, Head of Generative AI Product at Canva. In this episode of The Cognitive Revolution, we dive into Canva's innovative approach to AI integration, from task automation to human augmentation. Join us for an insightful discussion about fine-tuning foundation models, AI's impact on arc…
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In this episode of The Cognitive Revolution, we dive deep into frontier post-training techniques for large language models with Nathan Lambert from the Allen Institute for AI. Nathan discusses the groundbreaking Tulu 3 release, which matches Meta's post-training performance using the LlAMA base model. We explore supervised fine-tuning, preference-b…
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Have you ever wondered what makes a great biotech CMO? In this episode of the Emerging Biotech Leader, Dr. Steven Zelenkofske shares the practical, hard-earned insights he’s gained from his five CMO positions and multiple board roles, offering straightforward advice on how CMOs can step in early, build strong executive relationships, and drive clin…
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In this episode of The Cognitive Revolution, Nathan welcomes back Zvi Mowshowitz for an in-depth discussion on the latest developments in AI over the past six months. They explore Ilya's new superintelligence-focused startup, analyze OpenAI's O1 model, and debate the impact of Claude's computer use capabilities. The conversation covers emerging par…
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In this episode of The Cognitive Revolution, Nathan explores AI forecasting and AGI Lab oversight with Dean W. Ball and Daniel Kokotajlo. They discuss four proposed requirements for frontier AI developers, focusing on transparency and whistleblower protections. Daniel shares insights from his experience at OpenAI, while Dean offers his perspective …
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In this episode of The Future of Identity Podcast, I’m joined by David Kelts, a leader in digital identity and mobile ID initiatives, with a career that spans significant contributions across multiple companies and initiatives worldwide. David's insights shed light on the journey of mobile driver’s licenses (mDLs), the evolution of identity verific…
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The relationship between biotech leadership and their boards is evolving, particularly as private equity takes a larger role in the industry. In this episode of the Emerging Biotech Leader, Nick Amigone from Amulet Capital Partners offers a unique perspective on building effective board relationships from the private equity vantage point. The conve…
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In this special episode of The Cognitive Revolution, Nathan shares his thoughts on the upcoming election and its potential impact on AI development. He explores the AI-forward case for Trump, featuring an interview with Joshua Steinman. Nathan outlines his reasons for not supporting Trump, focusing on US-China relations, leadership approach, and th…
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In this special episode of The Cognitive Revolution, Nathan shares his thoughts on the upcoming election and its potential impact on AI development. He explores the AI-forward case for Trump, featuring an interview with Samuel Hammond. Nathan outlines his reasons for not supporting Trump, focusing on US-China relations, leadership approach, and the…
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Nathan interviews Google product managers Shrestha Basu Mallick and Logan Kilpatrick about the Gemini API and AI Studio. They discuss Google's new grounding feature, allowing Gemini models to access real-time web information via Google search. The conversation explores Gemini's rapid growth, its position in the AI landscape, and Google's competitiv…
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In this episode of The Cognitive Revolution, Nathan dives deep into the world of state space models with returning co-host Jason Meaux and special guest Quentin Anthony, Head of Model Training at Zyphra. Explore the cutting-edge Zamba 2-7b model, which combines selective state space and attention mechanisms. Uncover practical insights on model trai…
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Nathan discusses a tragic incident involving AI and mental health, using it as a springboard to explore the potential dangers of human-AI interactions. He reads a personal account from LessWrong user Blaked, who details their emotional journey with an AI chatbot. The episode delves into the psychological impact of AI companionship, the ethical conc…
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In this episode of The Cognitive Revolution, Nathan delves into the fascinating world of AI-generated research ideas with Stanford PhD student Chenglei Si. They discuss a groundbreaking study that pits AI against human researchers in generating novel AI research concepts. Learn about the surprising results that show AI-generated ideas scoring highe…
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How can biotech CEOs and their boards foster strong, trusting relationships that drive effective decision-making and long-term success? In this episode of Emerging Biotech Leader, host Kim Kushner explores this critical question together with Don de Bethizy. Don is a seasoned life sciences executive with over 30 years of experience, having served a…
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Join Nathan for an expansive conversation with Dan Hendrycks, Executive Director of the Center for AI Safety and Advisor to Elon Musk's XAI. In this episode of The Cognitive Revolution, we explore Dan's groundbreaking work in AI safety and alignment, from his early contributions to activation functions to his recent projects on AI robustness and go…
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In this special crossover episode of The Cognitive Revolution, Nathan introduces a conversation from The Inside View featuring Owain Evans, AI alignment researcher at UC Berkeley's Center for Human Compatible AI. Evans and host Michael Trazzi delve into critical AI safety topics, including situational awareness and out-of-context reasoning. Discove…
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Nathan hosts Professor Michael Levin and Staff Scientist Dr. Leo Pio Lopez from Tufts University in this episode of The Cognitive Revolution. They discuss their groundbreaking paper that combines biological datasets into a unified network model of disease using advanced embedding techniques. The conversation covers the technical details of their wo…
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In this episode of The Future of Identity Podcast, I’m joined by Rohan Pinto, Co-founder and CTO of 1Kosmos, a company at the forefront of decentralized identity and passwordless authentication solutions. We explore the evolution of identity management and the journey from blockchain-based beginnings to building secure, user-controlled identity sys…
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Nathan and co-host Stephen Parker delve into the world of AI video generation with Anastasis Germanidis, Co-Founder and CTO of Runway. This episode of The Cognitive Revolution explores the cutting-edge technology behind Runway's Gen 3 models and their impact on the creative industry. From emergent properties in scaled-up models to the democratizati…
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In this episode of "The Emerging Biotech Leader" podcast, host Ramin Frahood speaks with Helen Kargaryani, VP Global Head of Quality/Quality Services at SSI Strategy. With over 30 years of experience in the pharmaceutical and biotech industries, Helen shares her expertise on quality and risk management. Risk management in these industries is a crit…
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In this episode of The Cognitive Revolution, Nathan explores unconventional approaches to AI safety with Judd Rosenblatt and Mike Vaiana from AE Studio. Discover how this innovative company pivoted from brain-computer interfaces to groundbreaking AI alignment research, producing two notable results in cooperative and less deceptive AI systems. Join…
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In this special crossover episode of The Cognitive Revolution, Nathan shares an insightful conversation from the Latent.Space podcast. Swyx and Alessio interview Alistair Pullen of Cosine, creators of Genie, showcasing the cutting edge of AI automation in software engineering. Learn how Cosine achieves state-of-the-art results on the SWE-bench benc…
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Join Nathan for an insightful episode of The Cognitive Revolution with Wade Foster, co-founder and CEO of Zapier. Discover how this no-code pioneer is evolving into an AI-powered platform for the future of work. Learn about Zapier's ambitious vision, their integration of AI throughout their product, and how they're adapting as a company. From AI-dr…
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In this crosspost from the 80,000 Hours podcast, host Rob Wiblin interviews Nick Joseph, Head of Training at Anthropic, about the company's responsible scaling policy for AI development. The episode delves into Anthropic's approach to AI safety, the growing trend of voluntary commitments from top AI labs, and the need for public scrutiny of frontie…
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This episode offers critical insights on leveraging risk management as a strategic advantage in medical device development. In a conversation with Ramin Farhood, Bijan Elahi, with over 30 years of experience, provides a roadmap for integrating safety considerations into innovation pipelines, potentially accelerating time-to-market and enhancing com…
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In this episode of The Cognitive Revolution, Nathan explores the cutting-edge intersection of AI and biology with Stanford assistant professor Brian Hie. Discover how AI is revolutionizing our understanding of biological systems and creating new possibilities for interventions. Brian discusses his groundbreaking papers on hybrid AI architectures, t…
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In this sponsored episode of The Cognitive Revolution, Nathan interviews Andrei Oprisan, Engineering Lead at Agent.ai. They explore the cutting-edge world of AI agents and their impact on the future of work. Andrei shares insights on language model limitations, best practices for building AI agents, and Agent AI's vision as a professional network f…
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In this episode, I’m joined by Calvin Fabre, President and Founder of Envoc, a company that has been at the heart of mobile driver's license (mDL) innovation in Louisiana, a state leading the nation in mDL adoption. Calvin shares the fascinating story of how his company helped bring the country’s first digital driver’s license into reality, startin…
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In this Emergency Pod of The Cognitive Revolution, Nathan provides crucial insights into OpenAI's new O1 and O1-mini reasoning models. Featuring exclusive interviews with members of the O1 Red Team from Apollo Research and Hayes Labs, we explore the models' capabilities, safety profile, and OpenAI's pre-release testing approach. Dive into the impli…
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In this Emergency Pod of The Cognitive Revolution, Nathan provides crucial insights into OpenAI's new o1 and o1-mini reasoning models. Featuring exclusive interviews with members of the o1 Red Team from Apollo Research and Haize Labs, we explore the models' capabilities, safety profile, and OpenAI's pre-release testing approach. Dive into the impli…
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In this special cross-post episode of The Cognitive Revolution, Nathan shares a fascinating conversation between Spencer Greenberg and philosopher Nick Bostrom from the Clearer Thinking podcast. They explore Bostrom's latest book, "Deep Utopia," and discuss the challenges of envisioning a truly desirable future. Discover how advanced AI could resha…
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In this episode, Nathan explores the fascinating and controversial realm of AI consciousness with robo-psychologist Yeshua God. Through extended dialogues with AI models like Claude, Yeshua presents compelling evidence that challenges our assumptions about machine sentience and moral standing. Yeshua argues for a more nuanced approach to AI alignme…
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In this episode of The Cognitive Revolution, Nathan interviews Samo Burja, founder of Bismarck Analysis, on the strategic dynamics of artificial intelligence through a geopolitical lens. They discuss AI's trajectory, the chip supply chain, US-China relations, and the challenges of AI safety and militarization. Samo Burja brings both geopolitical ex…
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Nathan explores the emergence of computational life with Google researchers Ettore Randazzo and Luca Versari. In this episode of The Cognitive Revolution, we delve into their groundbreaking paper on self-replicating programs arising from simple interactions. Join us for a fascinating discussion on the implications for AI development, the origins of…
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The latest Emerging Biotech Leader podcast tackles the important topic of patient-focused drug development, offering valuable insights for the biotech industry. Our host Kim Kushner engages in an insightful dialogue with Dr. Laurie Smaldone-Alsup, SVP Regulatory Science at SSI Strategy, who brings years of hands-on regulatory experience to the conv…
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In this episode, I sit down with Karyl Fowler, co-founder and CEO of Transmute, a company at the forefront of integrating modern identity technology into global trade. Before founding Transmute, Karyl's work in the semiconductor and bioelectronics industries provided her with unique insights into the complexities of global supply chains. We explore…
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Nathan explores the cutting-edge world of AI-powered forecasting with Deger Turan, CEO of Metaculus. In this episode of The Cognitive Revolution, we discuss how AI is revolutionizing prediction markets, the potential for AI to outperform human forecasters, and Metaculus's ambitious new AI forecasting benchmark tournament. Join us for an insightful …
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Nathan Labenz discusses the latest developments in California's AI bill SB 1047 with experts Nathan Calvin, Dean W. Ball, and Steve Newman. In this episode of The Cognitive Revolution, we explore the updated version of the bill, its implications for frontier AI companies, and the debate surrounding its potential impact. Join us for an insightful an…
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Nathan presents a comprehensive AI automation framework developed over three years, applicable to process automation and generative AI integration. This episode of The Cognitive Revolution, offers critical insights for businesses looking to leverage AI effectively. Learn about choosing AI tasks, understanding work deeply, and optimizing AI performa…
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Nathan explores the cutting-edge field of mechanistic interpretability with Dan Balsam and Tom McGrath, co-founders of Goodfire. In this episode of The Cognitive Revolution, we delve into the science of understanding AI models' inner workings, recent breakthroughs, and the potential impact on AI safety and control. Join us for an insightful discuss…
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On this episode of Emerging Biotech Leader, Kim Kushner sits down with Edward M Kaye, M.D., CEO and director of Stoke Therapeutics, to talk about his work in rare disease drug development. Throughout their conversation, Ed describes the challenges of first-in-class drug development. He explains the importance of understanding diseases thoroughly an…
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In this episode, I talk with Kim Hamilton Duffy, the Executive Director of the Decentralized Identity Foundation (DIF). Before her work at DIF, Kim served as the CTO at Learning Machine, an early pioneer in the self-sovereign identity space that was acquired in 2020. We cover a range of topics, including: - The early days at Learning Machine and ho…
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In this special crossover episode of The Cognitive Revolution, Nathan Labenz joins Robert Wright of the Nonzero newsletter and podcast to explore pressing questions about AI development. They discuss the nature of understanding in large language models, multimodal AI systems, reasoning capabilities, and the potential for AI to accelerate scientific…
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