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Ever wondered how technology start-ups, well, start-up? For most founder entrepreneurs, it is the biggest experiment they'll ever run. Like most experiments, the result isn't known beforehand and it often doesn't work first time. On a bigger scale, how do big tech companies turn innovative science into profit? Mark Davison interviews founder scientists, executives, investors, communicators, and others in the technology start-up and corporate science ecosystems. Learn how great ideas turned i ...
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Men’s fertility is falling and fast. In the last 50 years sperm counts are down by 60%. Yet this is still a topic that no one is really talking about. My guest in this episode, Lily Elsner, is the co-founder and CEO of Jack Fertility. They are trying to break the taboo with thier product, the world’s first postable sperm test kit. Lily discusses th…
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This edition of The Big Experiment is a little bit different to the usual format. I'm on the road visiting the famous University of Cambridge Judge Business School to talk to people at the Ignite program. It’s an intensive weeklong boot camp for early-stage founders, generally in tech and sometimes in biotech, but can be all sorts of different tech…
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My son was diagnosed with type 1 diabetes at the age of 13. Which is why this episode is very close to my heart. There are big life-altering challenges for the patient and their family in managing type 1 diabetes. With limitations to the current insulin therapies that make the work of my guest in the episode, Mike Teiler, all the more important. Mi…
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The challenges of scientific entrepreneurship don’t end when you get funding. In fact, a whole new set of challenges arise, from finding labs, to building your team and more. In this episode I talk to Dr. Kärt Tomberg, CEO and co-founder of ExpressionEdits. She is now at that exact moment, where she has just secured £10 million of funding. So, who …
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Would you have the guts to pitch directly to the customer to sell your idea? You need to be prepared to hear no a lot, and learn from the experience to adapt for the next time, to get the yes you need. This was the reality faced by my guest in this episode, Ruchi Sharma, CEO & Founder of Stemnovate Limited. She used that customer-first approach and…
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It is a guilty secret that the pharma and biotech industry has a big carbon footprint. Single-use plastics are a huge problem. Sensitive experiments need clean, sterile labware. This has often meant using virgin plastic with little or no recycling or reuse. Innovative approaches are needed to reduce plastic consumption in the lab. How bad is bad? O…
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Imagine being able to internalise the pharmaceutical factory into the human. You could avoid the contamination risks and need for purification in biologic production. In this episode I am joined by Dr James Dooley who is doing just this with his work at Aila Biotech. James and his team developed technology to drive the production of immune-regulati…
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The global population is getting older and with that comes more disease. What if we could delay ageing as a way of treating those diseases? My guest in this episode is Janette Thomas, CEO of Five Alarm Bio Ltd., a drug discovery company focusing on novel approaches to anti-aging, with broad potential therapeutic applications. She discusses the appl…
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Imagine having to climb a mountain every day just to get to school. This was the childhood of my guest George Adjabeng. George Adjabeng grew up in Ghana, the son of subsistence farmers. He excelled at chemistry in school and college, and emigrated to the USA to pursue a pharmaceutical career before turning entrepreneur. His successful company Ecody…
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What is the future of DNA and gene synthesis? Before the covid pandemic, nucleic acids were mostly research tools. Terms like mRNA vaccines (nucleic acids as clinical agents) were relatively unknown. But since then, RNA and DNA have been thrust into the limelight for both the public and investors alike. How will the field evolve? My guest in this e…
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What are the biggest challenges facing scientific innovation? The path from science ideation to business execution is not an easy one. You will eventually need to translate great ideas into well-positioned products or services, and bring investment into the business from what can be a complex ecosystem of stakeholders. Knowing how to overcome these…
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Welcome to The Big Experiment, where we explore the scientific business world, and find out how great ideas turn into great companies. I'm Mark Davison CEO of Grant Instruments, a scientific insurance (instruments) company based in Cambridge, UK. But I'm also a veteran of pharmaceutical and biotech roles from drug discovery, right through to medici…
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