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Defective by Design

Jared Skinner and Matthew Rosenberg

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A podcast for the misfits and rebels of the design world...and for those who appreciate them. Join Jared Skinner and Matthew Rosenberg, as they share their views on architecture, design, entrepreneurship, and making it in the real world.
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Join the nano-rare disease community! Interviews features leading physicians, scientists, biotech experts, and patient advocates. Lessons teach core concepts about drugs. Our host Dr. Crooke has led the creation of antisense technology and his foundation, n-Lorem, is using this powerful technology to discover, develop, and provide personalized experimental antisense oligonucleotide medicines to nano-rare patients for free, for life. n-Lorem is a non-profit organization established to apply t ...
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Dental Digest Podcast with Dr. Melissa Seibert

Dental Digest Institute & Dr. Melissa Seibert: Dentist

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The Dental Digest podcast is a show dedicated to discussing the latest trends, topics, and innovations in the field of dentistry. The podcast was created and is hosted by Dr. Melissa Seibert, a practicing dentist, and features interviews with leading experts in the field of dentistry, including dentists, researchers, educators, and industry professionals. Topics covered on the show range from clinical techniques and technology to practice management and marketing strategies, with a focus on ...
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Welcome to "Making a Great America," a podcast dedicated to exploring the meticulous thought and effort that went into the design of the Constitution of the United States. This series is intended as a non-partisan historical review, aimed at enlightening listeners of all political persuasions about the foundational principles of our government. Our goal is to share the rich history behind the Constitution and the reasons why understanding this history is crucial for the survival of our repub ...
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Get on the waitlist for journal club here: https://www.dentaldigestpodcast.com/contact-4 Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Corky Willhite has had a special interest in Cosmetic Dentistry since this rapidly progressing field…
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The Anti-Federalists were a diverse group who opposed the 1787 Constitution, fearing it concentrated too much power in a centralized government. Despite being labeled "anti-American," their commitment to individual liberties and skepticism of government overreach led to the adoption of the Bill of Rights. Their key concerns included the absence of …
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Federalist Paper No. 21, authored by Alexander Hamilton, critiques the Articles of Confederation, highlighting key deficiencies: the lack of federal enforcement power, unreliable national finances, and inconsistent national defense. Hamilton argues that without direct authority, the federal government cannot enforce laws effectively, leading to cha…
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Federalist Paper #22, written by Alexander Hamilton, addresses the weaknesses of the Articles of Confederation, emphasizing the need for a stronger central government. He highlights issues such as the lack of a unified national defense, inadequate regulation of commerce, and the inability to enforce laws uniformly across states. Hamilton argues tha…
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Anti-Federalist Paper Brutus No. 1, likely written by Robert Yates, argues against the ratification of the proposed U.S. Constitution. Brutus fears that the Constitution grants too much power to the federal government, risking the erosion of state sovereignty and individual liberties. He contends that a large republic would struggle to adequately r…
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Federalist Paper #18, co-authored by Alexander Hamilton and James Madison, examines the failures of ancient confederacies such as the Amphictyonic Council and the Achaean League to argue for a stronger union under the proposed U.S. Constitution. These historical leagues suffered from weak central authority, internal strife, and susceptibility to ma…
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Federalist Paper #16, authored by Alexander Hamilton, advocates for the ratification of the United States Constitution by highlighting the critical weaknesses of the Articles of Confederation. Hamilton argues that the current system's inability to enforce laws directly on individuals leads to ineffective governance and potential conflicts among sta…
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Federalist Paper #17 by Alexander Hamilton assures that the proposed Constitution does not threaten state sovereignty. Hamilton argues that the federal government's focus on national issues like defense and commerce, coupled with the strong attachment people have to their local governments, will prevent federal overreach into state affairs. He emph…
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Federalist Paper No. 20, authored by James Madison and Alexander Hamilton, critiques the weak governance structure of the United Netherlands to highlight the flaws in the Articles of Confederation. The paper argues that the Dutch confederation’s lack of centralized authority led to frequent internal conflicts and an inability to effectively respond…
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Federalist Paper #19, authored by James Madison, argues for the necessity of a strong central government to ensure stability, security, and effective governance in the United States. Madison examines the failures of historical confederacies, such as the Holy Roman Empire and the Polish-Lithuanian Commonwealth, to illustrate the dangers of weak cent…
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In this episode of "Making a Great America," Charlie Jett explores Federalist Paper No. 15, where Alexander Hamilton critiques the Articles of Confederation and argues for a stronger central government. Hamilton highlights the failures of the Articles in enforcing laws, regulating commerce, and raising revenue, emphasizing the need for a government…
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In this episode of "Making a Great America," Charlie Jett explores Federalist Paper No. 14, where James Madison argues for the viability and benefits of a large republic. Madison addresses concerns about the nation's vast size, emphasizing that a system of representation and advancements in infrastructure and communication make effective governance…
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In Federalist Paper No. 13, Alexander Hamilton presents a detailed and compelling case for the economic advantages of a unified government. He argues that a single, consolidated government can reduce administrative costs, manage resources more efficiently, maintain a cost-effective defense, simplify governance, and prevent inter-state economic conf…
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The affected organs of our patients determine the route of administration for an ASO, as certain routes can better target specific organs and offer the best potency. The central nervous system (CNS) is the most common target we encounter, and for this, we dose intrathecally. Let’s dive into how this is done and the particulars of why this approach …
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Federalist Paper No. 12, written by Alexander Hamilton, argues for the importance of a unified government in efficiently collecting revenue, essential for the nation’s stability and growth. Hamilton emphasizes that a strong federal system enhances tax collection, supports economic growth, and prevents tax evasion and smuggling. He highlights that c…
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Federalist Paper No. 11, written by Alexander Hamilton, argues for the economic and military advantages of a united America. Hamilton emphasizes that a unified government can enhance America's global commercial influence, negotiate better trade terms, and develop a powerful navy to protect national interests. He highlights the benefits of free inte…
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Get on the waitlist for journal club here: https://www.dentaldigestpodcast.com/contact-4 Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Specialty Orofacial Pain Diplomate of the American Board of Orofacial Pain Fellow of the American Academ…
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Federalist Paper No. 10, authored by James Madison, addresses the dangers of factionalism and argues for a large republic to mitigate its effects. Madison defines factions as groups of citizens with interests contrary to the rights of others or the interests of the whole community. He asserts that a large republic can better control factions becaus…
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Federalist Paper #9, written by Alexander Hamilton, argues for the benefits of a strong union as a means to ensure domestic tranquility and prevent factions and insurrections. He references historical examples, such as the confederacies of ancient Greece and modern Europe, which failed due to internal conflicts. Hamilton asserts that a well-constru…
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Federalist Paper #8 articulates Alexander Hamilton’s nuanced views on military policy and the imperative of maintaining a vigilant yet restrained approach to the use of armed forces in a republican government. His arguments provide valuable insights into the Founders’ concerns about balancing national security with the preservation of liberty, a ba…
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In Federalist Paper #7, Hamilton passionately champions a powerful federal government as essential for America's prosperity and security. He vividly portrays the chaos of states grappling with trade barriers and regulatory clashes under the Articles of Confederation, stifling economic potential. Hamilton's vision extends beyond commerce; he envisio…
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Alexander Hamilton, in Federalist Paper #6, argues for a strong federal government to prevent conflicts among the states and ensure national stability. He uses historical examples to show that states, even republics, are prone to rivalry and war. Hamilton emphasizes the role of human nature and economic competition in driving states towards conflic…
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In Federalist Paper No. 2, John Jay argues for the necessity of a strong, unified government under the proposed U.S. Constitution. He emphasizes the shared heritage, values, and interests of the American people, advocating for a federal government capable of ensuring national security, managing conflicts, and promoting the common good. Jay critique…
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In Federalist Paper No. 4, John Jay argues that a strong, unified federal government is crucial for national defense and foreign policy. He asserts that a single government can better protect the nation from foreign threats and aggressions compared to separate, individual states. Jay highlights that a united America will be more respected and capab…
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In Federalist Paper #5, John Jay emphasizes the necessity of a strong federal union for defense against external threats, economic prosperity through improved trade relations, and maintenance of domestic peace. He argues that a divided nation would be vulnerable to foreign interference and conquest, highlighting historical examples to underscore th…
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In Federalist Paper No. 3, John Jay argues that a strong, unified federal government is essential for national security and peace. He asserts that a single government will be more effective in avoiding wars and conflicts with foreign nations and between states. Jay emphasizes that a united America can better uphold treaties and international laws, …
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In Federalist Paper No. 1, Alexander Hamilton introduces the series of essays advocating for the ratification of the U.S. Constitution. He emphasizes the significance of a strong, unified federal government for national stability and prosperity. Hamilton outlines the inadequacies of the Articles of Confederation and addresses the critical decision …
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Welcome to the Introductory Episode of the Making a Great America Podcast Hello and welcome to the Making a Great America podcast! This is our very first episode, and we're thrilled to have you with us on this journey. What is This Podcast All About? Making a Great America is dedicated to exploring the visionary ideals of the Founding Fathers and t…
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Get on the waitlist for journal club here: https://www.dentaldigestpodcast.com/contact-4 Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Dennis Hartlieb is a graduate of the University of Michigan School of Dentistry and maintains a full…
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Konstantina Skourti-Stathaki leads the n-Lorem research team behind the design and discovery of ASOs. Nadina, as we at n-Lorem call her, has a passion for helping patients and an excitement for science that is contagious. She joins the Patient Empowerment Program podcast to discuss her day-to-day activities as n-Lorem’s Director of ASO Design and D…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. McClintock is a graduate of the State University of New York at Buffalo School of Dental Medicine (2016), where she graduated with honors and a minor concentration in esthetics. She complet…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Robert Stanley has been interested in dentistry since spending hours in his grandfather’s dental office in Chicago as a child. After his grandfather passed away, Dr. Stanley became interest…
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We’re recapping the 2023 Nano-rare Patient Colloquium in this special “Best of” episode. For the Colloquium, we gathered the nano-rare community under one single roof for a full day of presentations and panels with experts, partners, supporters, and patients. So, we are bringing some of the top moments directly to your speakers. Discover the origin…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Lotardo has earned Accredited status in the AACD—an accomplishment completed by only 405 dental professionals in the history of the association, showcasing his commitment to excellence in t…
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What's preventing insurers from covering the specialized care of patients with nano-rare mutations, thereby expanding access to available treatment options? Is it the population size, cost, or perceived risk? Given that the initial discovery of nano-rare mutations is relatively recent, paving the way for this population requires a nuanced approach …
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https://www.robbinsdds.com/ https://www.mystoneoakdental.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off J. William Robbins, D.D.S., MA., maintains a full-time private practice and is an Adjunct Clinical Professor in the Department of C…
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https://www.robbinsdds.com/ https://www.mystoneoakdental.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off J. William Robbins, D.D.S., MA., maintains a full-time private practice and is an Adjunct Clinical Professor in the Department of C…
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Stan Crooke speaks with Sonja Kampfer and Dr. Neil Shneider, associate professor of motor neuron disorders at Columbia Medical School, about Sonja’s daughter, Anna. Anna was diagnosed with an aggressive, fatal form of ALS at the age of 16. ALS is rare in teenagers, and this form of ALS is the worst of the worst. Sonja tells Anna’s story initial sym…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Gustavo Avila-Ortiz obtained a DDS degree and completed a PhD training program at the University of Granada (Spain), before moving to Ann Arbor, Michigan (USA) where he graduated with an MS…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Gustavo Avila-Ortiz obtained a DDS degree and completed a PhD training program at the University of Granada (Spain), before moving to Ann Arbor, Michigan (USA) where he graduated with an MS…
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Motherhood is a journey filled with challenges, but every step is worth it for the love and joy it brings. Zoe Hummel joins the show in this special Mother’s Day episode to discuss her son Mostyn’s emotional story to diagnosis, and the unique challenges and triumphs of being a nano-rare mom. Order your Mother's Day card by May 6, 2024! All proceed …
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Gustavo Avila-Ortiz obtained a DDS degree and completed a PhD training program at the University of Granada (Spain), before moving to Ann Arbor, Michigan (USA) where he graduated with an MS…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Dichter brings nearly 20 years of clinical, research and teaching experience — as a general practitioner and prosthodontist — to his position with Spear. He serves as an instructor in the T…
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Research physicians and their associated institutions are monumental to the mission of the n-Lorem Foundation and are truly transformational to the lives of the nano-rare patients they treat. Olivia Kim-McManus, M.D., was one of four physician panelists at our first Colloquium who participated in "A Physician's Perspective on n-Lorem and Nano-rare"…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Dichter brings nearly 20 years of clinical, research and teaching experience — as a general practitioner and prosthodontist — to his position with Spear. He serves as an instructor in the T…
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Genetics can be intricate, no doubt. With millions of mutations present in every human, one might wonder why not everyone is impacted by pathogenic diseases. The Patient Empowerment Program aims to assist you in grasping the fundamental concepts of various mutations and how they function, paving the way for you to enhance your understanding of gene…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off About Dr. Lim: "I’m a dentist with a special interest in helping children overcome challenges with infant feeding, swallowing, breathing, chewing, and speech. I do this through a collaborative …
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I’m a dentist with a special interest in helping children overcome challenges with infant feeding, swallowing, breathing, chewing, and speech. I do this through a collaborative team approach to tongue tie management, and promoting good oral function and good jaw development. When oral function and jaw development is off track in childhood, it affec…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Todd Schoenbaum is Professor (full) at the Dental College of Georgia where he trains residents and students in implant restorations and clinical research. He serves as the DCG Coordinator for C…
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Each time one of the cells in your body divides to form a new cell, 3 BILLION genetic letters must be accurately duplicated. That’s a big number and mistakes DO happen in everyone. That’s right, if you’re reading this, you have a genetic mutation. On This Episode We Discuss: Your genetic alphabet – nucleotides How to think about DNA Replication Typ…
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