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Defective by Design

Jared Skinner and Matthew Rosenberg

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Daily+
 
A podcast for the misfits and rebels of the design world...and for those who appreciate them. Join Jared Skinner and Matthew Rosenberg, as they share their views on architecture, design, entrepreneurship, and making it in the real world.
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Join the nano-rare disease community! Interviews features leading physicians, scientists, biotech experts, and patient advocates. Lessons teach core concepts about drugs. Our host Dr. Crooke has led the creation of antisense technology and his foundation, n-Lorem, is using this powerful technology to discover, develop, and provide personalized experimental antisense oligonucleotide medicines to nano-rare patients for free, for life. n-Lorem is a non-profit organization established to apply t ...
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Dental Digest Podcast with Dr. Melissa Seibert

Dental Digest Institute & Dr. Melissa Seibert: Dentist

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The Dental Digest podcast is a show dedicated to discussing the latest trends, topics, and innovations in the field of dentistry. The podcast was created and is hosted by Dr. Melissa Seibert, a practicing dentist, and features interviews with leading experts in the field of dentistry, including dentists, researchers, educators, and industry professionals. Topics covered on the show range from clinical techniques and technology to practice management and marketing strategies, with a focus on ...
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Join Journal Club Download my free guide to Internal Bleaching PDF Follow @dental_digest_podcast Instagram Connect on Instagram: @dr.melissa_seibert on Instagram DOT - Use the Code DENTALDIGEST for 10% off Dr. Stephanie Tran is an endodontist who is passionate about endodontic education and helping patients relieve their dental pain while helping t…
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The knowledge we are gaining at n-Lorem has even more value than benefiting nano-rare patients and their families. These insights will enable scientists to discover new therapeutic targets for both common and rare diseases, fundamentally changing the way we approach health and disease. Survey – Patient Empowerment Program Podcast Register for the 2…
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Join Journal Club Download my free guide to Internal Bleaching PDF Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Qualified at the Royal London Hospital in 1995; achieving a number of awards including The Constance Klein Memorial, The Staff…
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Paul Compton and his wife Andrea chose to start a family through adoption. Unknown to anyone, one of their adopted boys, Taeson, was the inheritor of DRPLA, a progressive brain disorder caused by a mutation in the ATN1 gene. Determined to find a treatment and advocate for their son and others with the disease, the Comptons established CureDRPLA. In…
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JOIN JOURNAL CLUB Download my free guide to Internal Bleaching PDF Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Kokich Jr. received his dental degree from Tufts University School of Dental Medicine in 1996 and completed a general prac…
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Mutations affecting ion channels are the most common cause of 'applications for treatment' submitted to n-Lorem. These channels regulate the passage of essential electrically charged ions, like sodium, potassium, calcium, and chloride, into cells. Alas, ion channels pose a significant challenge in the ASO discovery process, as there is little room …
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Get on the waitlist for journal club here: https://www.dentaldigestpodcast.com/contact-4 Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Corky Willhite has had a special interest in Cosmetic Dentistry since this rapidly progressing field…
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The affected organs of our patients determine the route of administration for an ASO, as certain routes can better target specific organs and offer the best potency. The central nervous system (CNS) is the most common target we encounter, and for this, we dose intrathecally. Let’s dive into how this is done and the particulars of why this approach …
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Get on the waitlist for journal club here: https://www.dentaldigestpodcast.com/contact-4 Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Specialty Orofacial Pain Diplomate of the American Board of Orofacial Pain Fellow of the American Academ…
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Get on the waitlist for journal club here: https://www.dentaldigestpodcast.com/contact-4 Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Dennis Hartlieb is a graduate of the University of Michigan School of Dentistry and maintains a full…
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Konstantina Skourti-Stathaki leads the n-Lorem research team behind the design and discovery of ASOs. Nadina, as we at n-Lorem call her, has a passion for helping patients and an excitement for science that is contagious. She joins the Patient Empowerment Program podcast to discuss her day-to-day activities as n-Lorem’s Director of ASO Design and D…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. McClintock is a graduate of the State University of New York at Buffalo School of Dental Medicine (2016), where she graduated with honors and a minor concentration in esthetics. She complet…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Robert Stanley has been interested in dentistry since spending hours in his grandfather’s dental office in Chicago as a child. After his grandfather passed away, Dr. Stanley became interest…
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We’re recapping the 2023 Nano-rare Patient Colloquium in this special “Best of” episode. For the Colloquium, we gathered the nano-rare community under one single roof for a full day of presentations and panels with experts, partners, supporters, and patients. So, we are bringing some of the top moments directly to your speakers. Discover the origin…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Lotardo has earned Accredited status in the AACD—an accomplishment completed by only 405 dental professionals in the history of the association, showcasing his commitment to excellence in t…
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What's preventing insurers from covering the specialized care of patients with nano-rare mutations, thereby expanding access to available treatment options? Is it the population size, cost, or perceived risk? Given that the initial discovery of nano-rare mutations is relatively recent, paving the way for this population requires a nuanced approach …
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https://www.robbinsdds.com/ https://www.mystoneoakdental.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off J. William Robbins, D.D.S., MA., maintains a full-time private practice and is an Adjunct Clinical Professor in the Department of C…
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https://www.robbinsdds.com/ https://www.mystoneoakdental.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off J. William Robbins, D.D.S., MA., maintains a full-time private practice and is an Adjunct Clinical Professor in the Department of C…
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Stan Crooke speaks with Sonja Kampfer and Dr. Neil Shneider, associate professor of motor neuron disorders at Columbia Medical School, about Sonja’s daughter, Anna. Anna was diagnosed with an aggressive, fatal form of ALS at the age of 16. ALS is rare in teenagers, and this form of ALS is the worst of the worst. Sonja tells Anna’s story initial sym…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Gustavo Avila-Ortiz obtained a DDS degree and completed a PhD training program at the University of Granada (Spain), before moving to Ann Arbor, Michigan (USA) where he graduated with an MS…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Gustavo Avila-Ortiz obtained a DDS degree and completed a PhD training program at the University of Granada (Spain), before moving to Ann Arbor, Michigan (USA) where he graduated with an MS…
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Motherhood is a journey filled with challenges, but every step is worth it for the love and joy it brings. Zoe Hummel joins the show in this special Mother’s Day episode to discuss her son Mostyn’s emotional story to diagnosis, and the unique challenges and triumphs of being a nano-rare mom. Order your Mother's Day card by May 6, 2024! All proceed …
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Gustavo Avila-Ortiz obtained a DDS degree and completed a PhD training program at the University of Granada (Spain), before moving to Ann Arbor, Michigan (USA) where he graduated with an MS…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Dichter brings nearly 20 years of clinical, research and teaching experience — as a general practitioner and prosthodontist — to his position with Spear. He serves as an instructor in the T…
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Research physicians and their associated institutions are monumental to the mission of the n-Lorem Foundation and are truly transformational to the lives of the nano-rare patients they treat. Olivia Kim-McManus, M.D., was one of four physician panelists at our first Colloquium who participated in "A Physician's Perspective on n-Lorem and Nano-rare"…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Dr. Dichter brings nearly 20 years of clinical, research and teaching experience — as a general practitioner and prosthodontist — to his position with Spear. He serves as an instructor in the T…
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Genetics can be intricate, no doubt. With millions of mutations present in every human, one might wonder why not everyone is impacted by pathogenic diseases. The Patient Empowerment Program aims to assist you in grasping the fundamental concepts of various mutations and how they function, paving the way for you to enhance your understanding of gene…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off About Dr. Lim: "I’m a dentist with a special interest in helping children overcome challenges with infant feeding, swallowing, breathing, chewing, and speech. I do this through a collaborative …
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I’m a dentist with a special interest in helping children overcome challenges with infant feeding, swallowing, breathing, chewing, and speech. I do this through a collaborative team approach to tongue tie management, and promoting good oral function and good jaw development. When oral function and jaw development is off track in childhood, it affec…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Todd Schoenbaum is Professor (full) at the Dental College of Georgia where he trains residents and students in implant restorations and clinical research. He serves as the DCG Coordinator for C…
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Each time one of the cells in your body divides to form a new cell, 3 BILLION genetic letters must be accurately duplicated. That’s a big number and mistakes DO happen in everyone. That’s right, if you’re reading this, you have a genetic mutation. On This Episode We Discuss: Your genetic alphabet – nucleotides How to think about DNA Replication Typ…
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Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin DOT - Use the Code DENTALDIGEST for 10% off Todd Schoenbaum is Professor (full) at the Dental College of Georgia where he trains residents and students in implant restorations and clinical research. He serves as the DCG Coordinator for C…
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PARAMOUNT DENTAL STUDIO. DOT - Use the Code DENTALDIGEST for 10% off https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin Born on 10th of August 1974 in Alessandria, Italy. Graduated in Dental School at Genoa University as DDS in 1999. ADHESTHETICS founder.…
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What's one way to spread hope? By sharing your experiences and connecting with others who truly understand the everyday challenges nano-rare patients face. Shanna Tolbert was one of five nano-rare patient caregivers who participated in the panel, The Perilous Journey to Diagnosis and Treatment for Nano-rare Disease Patients. Listen to Shanna’s take…
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PARAMOUNT DENTAL STUDIO. DOT - Use the Code DENTALDIGEST for 10% off https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin Born on 10th of August 1974 in Alessandria, Italy. Graduated in Dental School at Genoa University as DDS in 1999. ADHESTHETICS founder.…
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For n-Lorem’s Chief Operating Officer, Sarah Glass, the mission of n-Lorem is personal. Her son Ethan was diagnosed with a nano-rare mutation. A geneticist by training, she joined n-Lorem to oversee and direct the organization’s efforts to provide hope and potential help to those who need it most. It's more than just a job for her; she's powered by…
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PARAMOUNT DENTAL STUDIO. DOT - Use the Code DENTALDIGEST for 10% off https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin Tim Wright served as chair of the pediatric dentistry program. He has published over 200 peer reviewed manuscripts, edited two texts an…
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Charissa Lipman joins n-Lorem founder and CEO, and host of the Patient Empowerment Program Podcast, Dr. Stan Crooke, in this question-and-answer episode to discuss additional questions asked during the 2023 Nano-rare Patient Colloquium. Charissa attended the inaugural Colloquium in October 2023 and brings the perspective of a patient family member,…
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PARAMOUNT DENTAL STUDIO. DOT - Use the Code DENTALDIGEST for 10% off https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin Tim Wright served as chair of the pediatric dentistry program. He has published over 200 peer reviewed manuscripts, edited two texts an…
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PARAMOUNT DENTAL STUDIO. DOT - Use the Code DENTALDIGEST for 10% off https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin Dr. Morr, a dentist in Miami Florida is the owner and founder of TMprosthodontics. He is a specialist in Aesthetic, Implant, and Comple…
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We're diving into the archives to resurface this top downloaded episode from last year. Dan Doctoroff joined Patient Empowerment Program in February 2023 to talk about his mission to support a world where everyone with ALS lives. Dan is the former NYC deputy mayor for economics and former CEO of both Bloomberg L.P. and Sidewalk Labs. In this episod…
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PARAMOUNT DENTAL STUDIO. DOT - Use the Code DENTALDIGEST for 10% off https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin Dr. Morr, a dentist in Miami Florida is the owner and founder of TMprosthodontics. He is a specialist in Aesthetic, Implant, and Comple…
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PARAMOUNT DENTAL STUDIO. DOT - Use the Code DENTALDIGEST for 10% off https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin Mark A. Latta, D.M.D., M.S., professor of general dentistry,served as dean of the School of Dentistry from 2011 to 2021. Prior to the d…
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For the return of the patient empowerment program podcast, we’re recapping the 2023 Nano-rare Patient Colloquium in this special “Best of” episode. For the Colloquium, we gathered the nano-rare community under one single roof for a full day of presentations and panels with experts, partners, supporters, and patients. So, we are bringing some of the…
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Mark A. Latta, D.M.D., M.S., professor of general dentistry,served as dean of the School of Dentistry from 2011 to 2021. Prior to the dean’s appointment, he served as the Associate Dean for Research at Creighton University School of Dentistry since 1995. He personally has been awarded more than 140 research grants on prosthetic dental restorative m…
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PARAMOUNT DENTAL STUDIO. DOT - Use the Code DENTALDIGEST for 10% off https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin Dr. Bakeman is included in an elite group of less than 300 dentists worldwide who are Accredited by the American Academy of Cosmetic De…
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PARAMOUNT DENTAL STUDIO. DOT - Use the Code DENTALDIGEST for 10% off https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin Dr. Bakeman is included in an elite group of less than 300 dentists worldwide who are Accredited by the American Academy of Cosmetic De…
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PARAMOUNT DENTAL STUDIO. DOT - Use the Code DENTALDIGEST for 10% off https://www.oneplacecapital.com/ Follow @dental_digest_podcast Instagram Follow @dr.melissa_seibert on Instagram Connect with Melissa on Linkedin Dr. Bill Strupp was the inaugural speaker at the AACD founding meeting in 1984. Dr. Strupp is an Accredited Fellow with the American Ac…
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Nano-rare diseases strip power from families and this often leads to hopelessness, anger, and dread. However, channeling these intense emotions to carefully navigate risk/benefit decisions is within one’s control. n-Lorem is different than standard drug development settings. Every risk/benefit decision that n-Lorem makes is in the context of the in…
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