Welcome back to the Evidence-Based Hair Podcast! This episode continues our June theme on JAK inhibitors, focusing on their topical use for treating frontal fibrosing alopecia (FFA) and lichen planopilaris (LPP). We'll delve into a groundbreaking study by Dr. Maryanne Senna and colleagues from Boston, examining the effectiveness and side effects of…

Welcome back to another episode of the Evidence-Based Hair Podcast. This week, we continue our June theme of JAK inhibitors, focusing on the use of topical JAK inhibitors for treating frontal fibrosing alopecia (FFA) and lichen planopilaris (LPP). In this episode, we delve into a significant study by Dr. Maryanne Senna and colleagues from Boston, e…

Welcome to another episode of the Evidence-Based Hair Podcast. In this episode, Dr. Donovan delves into an insightful study by Zhao and colleagues, published in the Journal of the European Academy of Dermatology and Venereology, titled "Baricitinib Therapy for Pediatric Patients with Severe Alopecia Areata." This episode continues the June series d…

Welcome back to another episode of the Evidence-Based Hair Podcast! In this episode, we delve into a fascinating study on the use of generic tofacitinib for treating alopecia areata. This study, published in the Archives of Dermatologic Research, explores the effectiveness and safety of generic tofacitinib. With the recent availability of this cost…

In this June series of the podcast, we focus on JAK inhibitors. This episode kicks off with a detailed review of an Italian study published in Expert Opinion in Drug Safety, which examines the incidence and management of infections in patients with alopecia areata treated with JAK inhibitors. Dr. Donovan discusses the findings, emphasizing that abo…

In this episode, Dr. Jeff Donovan, a dermatologist and hair loss specialist, examines the effect of topical minoxidil in enhancing beard hair growth in men Dr. Donovan focuses on a study published in Sage Open Medicine Case Reports titled, "Facial Hair Enhancement with Minoxidil and Off-Label Use". This study highlights the impact of using topical …

In this episode, we will dive into fascinating recent studies about the side effects of Minoxidil, a widely-known medication for hair loss treatment. This podcast highlights new research regarding what Dr. Donovan calls "the OMAHA effect" (ORAL MINOXIDIL ALCOHOL HANGOVER ASSOCIATION), the surprising association between oral minoxidil use and exacer…

In this episode, we dive into a thought-provoking study by Sanfilippo and Friedman, "Survey of Dermatology Practitioners' Opinions and Prescribing Habits of Oral Minoxidil for the Treatment of Androgenetic Hair Loss". The study provides valuable insights into the perceptions of practitioners on oral minoxidil, an increasingly popular option for tre…

In this episode of the Evidence-Based Hair Podcast hair loss specialist Dr. Jeff Donovan breaks down the findings of a recent study comparing oral minoxidil and topical minoxidil in the treatment of male androgenetic alopecia. Published in JAMA Dermatology, the study challenged popular opinions by revealing similar performance between the two types…

This episode is dedicated to a fascinating subject – drug-induced alopecia areata. In addition to genetic factors, alopecia areata is also influenced by environmental factors such as infections and medications. In this episode, Dr Donovan highlights two studies: “A Cross-Sectional Analysis of Medications Used by Patients Reporting Alopecia Areata o…

Welcome to a new episode of the Evidence-Based Hair Podcast, where we discuss some questions surrounding the relationship between dupilumab and lymphoma. This episode dives deep into a study by Hasan and colleagues that explores the fascinating and somewhat controversial relationship between Dupilumab, a drug often used to treat atopic dermatitis p…

This is a recording from the live webinar was conducted live December 13, 2023. This is an annual event that is held every year in mid-December celebrating the top hair research studies. DERMATOPATHOLOGY Douglas A et al. Scalp Biopsy Influences Diagnostic Accuracy and Treatment in Black Women with Alopecia: A Retrospective Study. J Am Acad Dermatol…

The Evidence Based Hair podcast highlighs the latest research in hair loss. This episode addresses articles related to the risk of cardiovascular disease, blood clots and acne in dermatology patients using JAK inhibitors.By Dr Jeff Donovan

STUDIES REFERENCED IN THIS EPISODE Pastukhova E et al. Alopecia Areata as a Sequela of COVID-19 Vaccination: A Systematic Review J Cutan Med Surg. 2023 Jan-Feb;27(1):64-65. Wang C-W et al. Clinical characteristics and immune profiles of patients with immune-mediated alopecia associated with COVID-19 vaccinations. Clin Immunol. 2023 Oct:255:109737. …

STUDIES REVIEWED THIS WEEK: Chang R et al. Risk of autoimmune diseases in patients with COVID-19: A retrospective cohort study. EClinicalMedicine. 2023 Feb;56:101783 Tesch F et al. Incident autoimmune diseases in association with SARS-CoV-2 infection: a matched cohort study. Clin Rheumatol. 2023 Oct;42(10):2905-2914. Lim SG et al. Autoimmune and Au…

STUDIES REFERENCED IN THIS EPISODE: Workman K and Kindred C (starts at 2:10). Hair regrowth in a patient with central centrifugal cicatricial alopecia after a 2-month trial of baricitinib. JAAD Case Rep. 2023 Jul 28:39:109-111. Cook M et al (starts at 12:07). Use of low-level light therapy in management of central centrifugal cicatricial alopecia: …

ARTICLES COVERED THIS WEEK STUDY 1: Ong M et al (starts at 5:12). Low-dose oral minoxidil for androgenetic alopecia is not associated with clinically significant blood-pressure changes: a retrospective study. J Am Acad Dermatol. 2023 Oct 13:S0190-9622(23)02976-6. Sanabria et al. Prospective cardiovascular evaluation with 24-h Holter and 24-h ambula…

ARTICLES REFERENCED IN THIS EPISODE Krauss A (starts at 12:44). Why all randomised controlled trials produce biased results. Ann Med. 2018 Jun;50(4):312-322. Van Noreen R (starts at 15:33). Medicine is plagued by untrustworthy clinical trials. How many studies are faked or flawed? Nature. 2023 Jul;619(7970):454-458. Listen at https://youtu.be/_QLvz…

Studies Referenced in This Episode: Season 6 Episode 1 King B et al (starts at 4:07). When to expect scalp hair regrowth during treatment of severe alopecia areata with baricitinib: insights from trajectories analyses of patients enrolled in two phase III trials. Br J Dermatol. 2023 Sep 14:ljad253. Gargiulo L et al (starts at 30:22). Effectiveness …

On August 1, 2023, Dr Donovan announced the long awaited start of the Evidence Based Hair Fellowship training program. This is an online (virtual) training program for practitioners that wish to develop expertise in hair loss. The program runs Jan 2024 to August 2025 and participants meet once weekly for a three hour period (either on a Wednesday o…

Alopecia Areata Awareness Month - Recording from Sept 6 2023 Live Public Webinar hosted by Dr Donovan. Question 1 (starts at 3:50): Is the rate of alopecia areata going up ? Question 2 (starts at 7:45). What blood tests should be ordered for someone with alopecia areata? Question 3 (starts at 11:58). Do JAK inhibitors cure alopecia areata? Question…

Season 5 Ep 6By Dr Jeff Donovan

STUDIES REFERENCED IN THIS EPISODE Onamusi T et al (starts at 8:58). Clinical factors and hair care practices influencing outcomes in central centrifugal cicatricial alopecia. Arch Dermatol Res. 2023 May 15. doi: 10.1007/s00403-023-02630-5. Online ahead of print. Erinolaoluwa F et al (starts at 11:59). Hair regrowth in 2 patients with recalcitrant …

STUDIES REFERENCE IN THE EPISODE SWITCHING FROM TOFACITINIB TO BARICITINIB Kazmi A et al (starts at 12:33). Switching between tofacitinib and baricitinib in alopecia areata: A review of clinical response. J Am Acad Dermatol. 2023 Apr 4;S0190-9622(23)00532-7. RITLECITINIB IN ADOLESCENTS Hordinsky M et al (starts at 21:31). Efficacy and safety of rit…

Evidence Based Hair is a podcast that highlights new hair loss research from around the world. The first Monday of each month is dedicated to studies in androgenetic alopecia, telogen effluvium and traction alopecia. One can also listen to this podcast on a variety of podcast channels.By Dr Jeff Donovan

NON SCARRING ALOPECIA AFTER HYALURONIC ACID TEMPORAL LIFTING TECHNIQUES Landau M et al (starts at 9:05). Nonscarring alopecia after temporal lifting technique with dermal fillers. JAAD Case Rep. 2023 May 12;37:30-34 Coimbra D.D., and de Oliveira B.S (starts at 10:17). Supra-auricular lifting with fillers: new technique. J Cosmet Dermatol. 2016;8(4)…

DISEASE ASSOCIATIONS IN FRONTAL FIBROSING ALOPECIA Conic et al. Exploring the association between lichen planopilaris, cardiovascular and metabolic disorders. J Eur Acad Dermatol Venereol 2021 Nov;35(11):e826-e828. Joshi et al. Comorbidities associated with lichen planopilaris: a case-control study using the All of Us database. Int J Dermatol. 2022…

Season 4, Episode 8By Dr Jeff Donovan

Season 4, Episode 7 DataBy Dr Jeff Donovan

Season4, Episode 6By Dr Jeff Donovan

Season 4, Episode 5By Dr Jeff Donovan

Season 4 Episode 4 COVID RELATED TE Michelini S et al. Telogen Effluvium in SARS-CoV-2 Infection: histological aspects. J Eur Acad Dermatol Venereol. 2023 Mar 8. M Alharbi et al. Telogen effluvium after COVID-19 vaccination among public in Saudi Arabia. J Family Med Prim Care. 2022 Oct;11(10):6056-6060. Tahmaz A et al. [The Evaluation of Long Coron…

Season 4, Episode 3By Dr Jeff Donovan

STUDIES REFERENCED ROLE OF SCALP BIOPSIES IN BLACK WOMEN WITH HAIR LOSS Douglas A et al. Scalp Biopsy Influences Diagnostic Accuracy and Treatment in Black Women with Alopecia: A Retrospective Study. J Am Acad Dermatol. 2023 Jan 31;S0190-9622(23)00157-3. ORAL MINOXIDIL IN CHEMOTHERAPY RELATED HAIR LOSS Kang J et al. Efficacy of low-dose oral minoxi…

STUDIES REFERENCED PATHOLOGY OF NON SCARRING AND SCARRING ALOPECIA Amanda Araujo Dos Reis Botega et al. Scarring versus Non-Scarring Alopecia: An Interobserver Histopathological Reproducibility Study Skin Appendage Disord. 2023 Jan;9(1):34-41. doi: 10.1159/000526966. Epub 2022 Nov 25. HYDROXYCHLOROQUINE AND RETINOPATHY RISK Ronald B Melles RB et al…

The season finale summarizes the top 20 studies of the 2022 calendar year. This episode addresses studies in hair shedding, scarring alopecia, seborrheic dermatitis and hair straighteners (studies 12 to 20). Studies 1 to 11 are found in Part 1 (season 3 episode 9) STUDIES IN HAIR SHEDDING/TELOGEN EFFLUVIUM/ COVID19 STUDY 12: Muller-Ramos P et al. P…

The season finale summarizes the top 20 studies of the 2022 calendar year. This episode addresses studies in androgenetic alopecia and alopecia areata (studies 1 to 11). Studies 12 to 20 are found in Part 2 (season 3 episode 10) STUDIES IN FEMALE PATTERN HAIR LOSS AND MALE PATTERN HAIR LOSS STUDY 1: Qui Y et al. Systematic Review and Meta-analysis …

STUDIES REFERENCED ROLE OF CORTICOSTEROIDS IN THE JAK INHIBITOR ERA Licata G et al (starts at 7:21). Management of alopecia areata in JAK-inhibitors era: are systemic and topical corticosteroids still useful? Int J Dermatol. 2022 Nov 13. ALOPECIA AREATA AND PERIODONTITIS Kim JS et al (starts at 17:15). Periodontitis and risk of alopecia areata: A n…

A mix of recently published studies in hair loss IRON PILL GASTRITIS Koch R et al (starts at5 5:19). Case report: Rapid onset, ischemic-type gastritis after initiating oral iron supplementation. Front Med (Lausanne) 2022 Nov 3;9:1010897. Laine LA et al. (starts at 9:17). Effect of oral iron therapy on the upper gastrointestinal tract. A prospective…

LEARNING OBJECTIVES By the end of the podcast, the listener should be able to Discuss the benefits of HCQ in LPP Outline allergens that may be relevant in LPP/FFA Discuss the benefits of LDOM in LPP Describe the Renbok phenomenon and how it relates to FFA Outline the potential triggers for EPDS Describe the relationship between AKN and gout EFFICAC…

Season 3, Episode 5By Dr Jeff Donovan

Studies in Androgenetic Alopecia and Alopecia Areata STUDIES REFERENCED MINOXIDIL CONCENTRATIONS Singh et al (starts at 10:10). Does topical minoxidil at concentrations higher than 5% provide additional clinical benefit? Clin Exp Dermatol. 2022 Nov;47(11):1951-1955 Olsen EA, Dunlap FE, Funicella T et al (starts at 13:22). A randomized clinical tria…

Recording of the Evidence Based Hair Podcast for the Oct 24, 2022 issue. STUDIES REFERENCED Han JJ et al (starts at 5:28) Association of resilience and perceived stress in patients with alopecia areata: A cross-sectional study. J Am Acad Dermatol. 2022 Jul;87(1):151-153. Gressler J et al (starts at 20:55 ). Re-pigmentation of scalp hair - A feature…

Recording of the Evidence Based Hair Podcast for the Oct 17, 2022 issue. LICHEN PLANOPILARIS COMORBIDITY STUDIES Conic et al (starts 8:19). Exploring the association between lichen planopilaris, cardiovascular and metabolic disorders. J Eur Acad Dermatol Venereol 2021 Nov;35(11):e826-e828. Joshi et al (starts 9:59). Comorbidities associated with li…

Recording of the Evidence Based Hair Podcast for the Oct 11, 2022 issue. TINEA CAPITIS STUDIES Cukierman E et al (starts at 5:18). Alopecia and pet: a case report. Einstein (Sao Paulo). 2022 Jul 4;20:eRC6881. TELOGEN EFFLUVIUM - COVID 19 Visconti A et al (starts at 20:00) Cutaneous Manifestations of SARS-CoV-2 infection during the Delta and Omicron…

ORAL MINOXIDIL IN PEDIATRICS Jerjen R et al (starts at 12:33). Low-dose oral minoxidil improves global hair density and length in children with loose anagen hair syndrome. Br J Dermatol. 2021;184(5):977-978. Nicolas-Ruanes et al (starts at 15:33). Low-dose oral minoxidil for treatment of androgenetic alopecia and telogen effluvium in a pediatric po…

FRONTAL FIBROSING ALOPECIA : ISOTRETINOIN VS FINASTERIDE Rakowska A, et al (starts at 9:15). Efficacy of Isotretinoin and Acitretin in Treatment of Frontal Fibrosing Alopecia: Retrospective Analysis of 54 Cases. J Drugs Dermatol. 2017. Rokni GR et al (starts at 10:43). Evaluating the combined efficacy of oral isotretinoin and topical tacrolimus ver…

STUDIES REFERENCED COVID RELATED SHEDDING Mazeto IFS et al (starts at 6:09). Ultrastructural evidence for anagen hair follicle infection with SARS-CoV-2 in early-onset COVID-19 effluvium. J Eur Acad Dermatol Venereol. 2022 Jun 20. Czech T et al (starts at 14:30). Characteristics of Hair Loss after COVID-19: Systematic Scoping Review. J Cosmet Derma…

Kavadya T and Mysore V (starts at 5:24). Role of Smoking in Androgenetic Alopecia: A Systematic Review. Int J Trichology. 2022 Mar-Apr; 14(2): 41–48. Mosley JG and Gibbs AC (starts at 6;30). Premature grey hair and hair loss among smokers: a new opportunity for heatlh education? British Medical Journal 1996; 313: 1616. Su LH and Chen T H-H (starts …

JAK KINASE INHIBITORS AND SKIN CANCER Jalles et al (starts at 5:29). Skin cancers under Janus kinase inhibitors: A World Health Organization drug safety database analysis. Therapie. 2022 May 7;S0040-5957(22)00092-0. ISOTRETINOIN LAB MONITORING Xia E et al (starts at 13:36). Isotretinoin Laboratory Monitoring in Acne Treatment: A Delphi Consensus St…