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On Happy Sad Confused, Josh Horowitz gets nerdy and intimate with the biggest movie stars and filmmakers on the planet. Each and every week, you’ll hear in-depth, career-spanning conversations with everyone from Samuel L. Jackson and Scarlett Johansson to Christopher Nolan and Quentin Tarantino. If you’ve ever wanted to know what it was like to get casual with A-listers like Tom Hiddleston or Kristen Stewart (all HSC regulars), then come on in and join Josh on Happy Sad Confused.
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If you want to fully experience the world's coolest pop culture events, you have to know The Rules. Entertainment correspondents and insiders Josh Horowitz & Ben Lyons are your eyes and ears at the 2020 Sundance Film festival with exclusive interviews, movie reviews, and all the fun and flavor you can usually only get with a VIP pass.
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Join creator/executive producer/writer Alex De Rakoff and actors Rupert Grint and Luke Pasqualino as they discuss Crackle's original series, Snatch. Loosely based on the popular film of the same name, Snatch follows a group of young hustlers navigating London’s criminal underworld. Moderated by MTV’s Josh Horowitz.
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Biology is breaking out of the lab and clinic—and into our daily lives. Our new ability to engineer biology is transforming not just science, research, and healthcare, but how we produce our food, the materials we use, how we manufacture, and much, much more. From the latest scientific advances to the biggest trends, this show explores all the ways biology is today where the computing revolution was 50 years ago: on the precipice of revolutionizing our world in ways we are only just beginnin ...
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Kathleen Goldhar was so happy her friend Arya had finally found someone after a bad divorce. Mordechai Horowitz seemed perfect. Smart. Rich. Creative. But like so many things that seem to be perfect - it was too good to be true. Credits: Jessica Grimshaw- For USG Audio Josh Bloch- For USG Audio Jennifer Sears- For USG Audio Kathleen Goldhar- Host, Executive Producer, Producer Stuart Coxe- Executive Producer Michelle Shephard- Producer Alexis Green- Associate Producer Abhi Rahaja- Associate P ...
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The Digital Void Podcast is a weekly exploration of digital culture, media, technology, and memes, featuring critical and empowering conversations with experts at the forefront of our digital transformation. Hosted by Dr. Jamie Cohen and Josh Chapdelaine. Hosted on Acast. See acast.com/privacy for more information.
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Once Upon A Time
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Once Upon A Time

Disney-ABC Television Group Digital Broadcast Communications and Production

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Enter the imagination of master storytellers Edward Kitsis and Adam Horowitz as they reflect on the worlds and characters they’ve created for ABC’s hit show, “Once Upon A Time,” which returns with an all-new Season 2 premiere at 8/7c Sunday, Sept. 30. To submit a question about the show, go to facebook.com/OnceABC.
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The Morbid Anatomy Transmission is the official podcast of the Morbid Anatomy Museum in Brooklyn, New York. The Morbid Anatomy Museum is an exhibition, library, and event space that explores "the intersections of death, beauty, and that which falls between the cracks." On this podcast, host Molly McBride Jacobson interviews event hosts, experts, and eccentrics on topics relating to death culture and obscure history.
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The team at Stanford eCorner believes in the powerful combination of evidence and imagination. We share original stories from informed leaders in academia and industry that focus on innovation, startups, culture, and strategy. The goal: empower you to bring bold ideas to life. Stanford eCorner is led by the Stanford Technology Ventures Program (STVP), the entrepreneurship center in Stanford University’s School of Engineering.
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Gareth Edwards is no stranger to big scale sci-fi but his latest film, THE CREATOR, is something different, a rare wholly unique idea in a sea of franchises. Gareth joins Josh to talk about his filmmaking influences, from Spielberg to Cameron, and his experiences directing giant films like ROGUE ONE and GODZILLA. #happysadconfused #joshhorowitz #th…
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Today's episode features Aviv Regev, PhD, the Head and Executive VP of Genentech Research and Early Development, and founding co-chair of the Human Cell Atlas. She is joined by Vijay Pande of Bio + Health. Together, Aviv and Vijay talk about how Aviv's love of both abstractions and details led her to biology, how CRISPR really set the field into mo…
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David Goyer does not shy away from a challenge. Witness his current gig as the Executive Producer/director/show-runner for FOUNDATION. Now in its second season on Apple TV+ it's an awesome undertaking considering its pedigree as one of the seminal works of sci-fi by the great Isaac Asimov. But Goyer's resume is littered with such iconic properties.…
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Andrew Ng, PhD, a distinguished authority in the field of AI, is known for founding DeepLearning.AI and multiple other ventures. He also co-founded and led Google Brain and serves as an Adjunct Professor in Stanford University's Computer Science Department. In this episode, he is joined by Vijay Pande, founding partner of a16z Bio + Health. Andrew …
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In this encore episode of Happy Sad Confused, Josh chats with John Cena about his transition from wrestling to acting, the lessons he's learned along the way, and finding a friend and collaborator in James Gunn. UPCOMING EVENTS! 10/9 -- Come see Josh and Josh Gad & Andrew Rannells at the 92nd Street Y in NYC! Virtual tickets available too. Get your…
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Taissa Farmiga is back on the big screen with THE NUN 2 so we're looking back at her whole career in this 2022 chat! Plus Josh recaps his Toronto Film Festival experience. UPCOMING EVENTS! 10/9 -- Come see Josh and Josh Gad & Andrew Rannells at the 92nd Street Y in NYC! Virtual tickets available too. Get your tickets here! Check out the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠…
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Carl June, MD, an immunologist and oncologist at the University of Pennsylvania, joins Jorge Conde, general partner at a16z Bio + Health. Together, Carl and Jorge talked about Carl's pioneering work in CAR T therapy — including the terrifying moment where he thought he had accelerated one of his patient's deaths, how he started working in human imm…
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Josh wraps up his time at the Telluride Film Festival with a recap of ALL the films he saw (10 of them!) and then chats with THE BIKERIDERS director Jeff Nichols about his new movie, working with Austin Butler & Jodie Comer, and more. UPCOMING EVENTS! 10/9 -- Come see Josh and Josh Gad & Andrew Rannells at the 92nd Street Y in NYC! Virtual tickets …
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How does creative misuse of social media platforms inform the future of social media at large? Director of Curiouser Institute Reed Berkowitz highlights five popular ways people are engaging, interacting, and using social platforms - ranging from Life360 to Roblox - and what it means for how we imagine and create a social media future that enhances…
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Dan Nomura is a distinguished professor at UC Berkeley and an Investigator at the Innovative Genomics Institute, specializing in Chemical Biology and Molecular Therapeutics. He serves as the Director of the Novartis-Berkeley Translational Chemical Biology Institute and founded Frontier Medicines and Vicinitas Therapeutics. He’s also a16z Bio+Health…
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Rejoice, Fall is upon us and as any film lover knows that means great movies! Josh and NextBestPicture.com editor in chief Matt Neglia take a look at the upcoming Telluride Film Festival and all the exciting offers coming up in theaters this season. UPCOMING EVENTS! 10/9 -- Come see Josh and Josh Gad & Andrew Rannells at the 92nd Street Y in NYC! V…
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In this exclusive conversation from the Bio + Health BUILD summit, founding partner Ben Horowitz sits down with general partner Jorge Conde. They discuss everything from the inspiration behind Ben’s book The Hard Thing About Hard Things, how the open Internet was secured, the difference between wartime and peacetime CEOs, scaling culture, and under…
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Washington Post tech columnist and author of Extremely Online: The Untold Story of Fame, Influence, and Power on the Internet Taylor Lorenz explores the social history of the internet. How did Mommy Bloggers shape the creator economy? What is Vine's influence on today's social media ecosystem – and how can its demise be a lesson for creators and pl…
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After a stellar career as a stuntman and second unit director, Chad Stahelski has emerged as one of the preeminent action filmmakers working today, helming the 4 JOHN WICK films. He joins Josh for the first time to chat primarily about the latest film (SPOILERS ahead!) and his ambitions beyond the Wick franchise. Check out the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠…
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Happy Sad Confused's OPPENHEIMER continues with a deep dive with the brilliant cinematographer, Hoyte Van Hoytema! It's a rare extended chat with one of Christopher Nolan's closest collaborators. OPPENHEIMER is his 4th collaboration with Nolan after INTERSTELLAR, DUNKIRK, and TENET. Check out the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Happy Sad Confused patreon here⁠⁠…
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Together, Lloyd and Vijay chatted about how AI could change the practice of medicine, and what the implications are for medical students now and in the future. join Lloyd and Vijay as they discuss AI and medical education—from how students learn to how doctors become licensed.By Lloyd B. Minor, Kris Tatiossian, Olivia Webb, Vijay Pande
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David Harbour is back! And there's a lot to catch up on, from his new film GRAN TURISMO to the end of STRANGER THINGS and his MCU and DC future! [RECORDED PRIOR TO THE SAG-AFTRA STRIKE] SUPPORT OUR SPONSORS! ZocDoc -- Go to ⁠⁠ZocDoc.com/HappySad⁠⁠ NordVPN -- 🌏 Get Exclusive NordVPN deal here ➼ ⁠⁠https://nordvpn.com/HappySad⁠⁠ It’s risk-free with No…
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Together, Margaret and Julie chatted about Margaret’s background — and how she taught herself to program — her time at Devoted, and the advice she gives to healthtech CEOs. Join Margaret and Julie as they discuss building a developer-friendly environment in healthcare, introducing engineers to the complexity of the industry, and how AI might affect…
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With the release of HEART OF STONE, we're revisiting our 2022 chat with Jamie Dornan! Enjoy this career chat, from his beginnings alongside the likes of Eddie Redmayne and Andrew Garfield to FIFTY SHADES OF GREY to BELFAST. SUPPORT THE SHOW BY SUPPORTING OUR SPONSORS! ZocDoc -- Go to ZocDoc.com/HappySad NordVPN -- 🌏 Get Exclusive NordVPN deal here …
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Timothy Olyphant is always money in the bank as far as we're concerned, from GO to JUSTIFIED, from SCREAM 2 to STAR WARS. Here he talks about it all! SUPPORT THE SHOW BY SUPPORTING OUR SPONSORS! BetterHelp -- This episode is sponsored by BetterHelp. Visit BetterHelp.com/HSC today to get 10% off your first month To watch episodes of Happy Sad Confus…
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Together, Vijay and Zak talked about having been through AI winters and hype cycles before, and why they think this time could be different. They also talked about how AI could revolutionize the healthcare model — what Zak calls the “flipped clinic.” Join Zak and Vijay as they talk about how AI could flip the clinic, how foundation models could qui…
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Cores are everywhere. From the film-inspired Barbiecore to Cottagecore – but how does a new core threaten to surveil everyday people? On today’s episode, Jamie provides us with a dispatch about the differences between Cores and aesthetics, the ways Cores present themselves online and offline, and why #humancore should be viewed with a critical eye.…
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Ben McKenzie joins Josh to talk about his new career as an author investigating the crypto market with EASY MONEY! SUPPORT THE SHOW BY SUPPORTING OUR SPONSORS! BetterHelp -- This episode is sponsored by BetterHelp. Visit BetterHelp.com/HSC today to get 10% off your first month To watch episodes of Happy Sad Confused, subscribe to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Josh…
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Emily Blunt can do it all! Comedy. Drama. Action. And now a Christopher Nolan film can be added to the impressive resume with OPPENHEIMER. The DEVIL WEARS PRADA and SICARIO star join Josh for her first appearance on the podcast to talk about it all! To watch episodes of Happy Sad Confused, subscribe to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Josh's youtube channel here⁠⁠⁠⁠⁠…
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Dan Rosenthal, a provider network expert and the newest advisory partner for a16z Bio + Health, joins Julie Yoo, general partner. Together, they talk about the 101 and 201 of provider networks, tactical advice for digital health builders, and how AI could theoretically change the way networks are constructed.…
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How did an early YouTube vlog style return to popularity after a generation of TikTok and YouTube creators including Emma Chamberlain and Charli D'amelio went mainstream? On today's episode, Jamie and Josh discuss how early YouTube creators like Tyler Oakley pivoted from creating content for family and friends to developing a public personality tha…
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Cillian Murphy is may have worked with Christopher Nolan before (5 times no less!) but he's never been his leading man. He has more than met the moment in OPPENHEIMER and he's back on the pod to talk all about it! SUPPORT OUR SPONSORS RocketMoney -- Go to RocketMoney.com/HSC To watch episodes of Happy Sad Confused, subscribe to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Josh's…
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The holy grail of company building is finding product-market fit. But what most people don’t tell you is that once you’ve found it, product-market fit brings its own set of challenges, particularly when it comes to scaling rapidly and hiring the right executives at the right time. Drawing from their extensive experiences, a16z cofounder Ben Horowit…
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How will AI, algorithms, creators, and data transparency shape the future of Hollywood? On today's episode, Jamie and Josh dive into the key issues behind the SAG-AFTRA strike. How do major studios plan to use AI – and how can they come to an agreement with unions to ensure actors and writers are fairly compensated? How does a lack of data transpar…
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When Greg started out in science, he heard other researchers referring to certain targets as “undruggable.” In response, he’s devoted his life to drugging the undruggable, cofounding the field of chemical biology along the way. After a robust career founding multiple biotechs and serving as the cofounder, chairman, and CEO of FogPharma, he is the n…
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Christopher Nolan returns for his 3rd visit (!) to HAPPY SAD CONFUSED to discuss OPPENHEIMER, his amazing cast, James Bond, and more! To watch episodes of Happy Sad Confused, subscribe to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Josh's youtube channel here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠! Check out the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Happy Sad Confused patreon here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠! We've got discount codes to li…
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After his own health scare, Jeffrey got obsessed with how MRIs work—and decided that they were too unscientific to really track human health over time. In response, he built a new kind of imaging, creating a “digital twin” that can be tracked over time. And if health can be tracked over time, in theory it could eventually become as forecastable as …
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How did Barbie and Oppenheimer become a highly anticipated double feature audiences have named Barbenheimer? This week, Josh and Jamie explore the history behind one of the summer's most anticipated box office weekends. How did a falling out between Christopher Nolan and WBD lead to this weekend's double feature? How have studios done an effective …
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Since the last time Hayley Atwell appeared on the podcast she finally donned the shield for Marvel and joined the MISSION: IMPOSSIBLE franchise so there's a lot to catch up on! SUPPORT OUR SPONSORS ZocDoc -- Go to Zocdoc.com/HAPPYSAD and download the Zocdoc app for FREE. Then find and book a top-rated doctor today! BetterHelp -- This episode is bro…
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AI has the potential to save the world — that’s the thesis of Marc’s most recent article, linked below. This episode was recorded right after Marc published his article, live from a16z Bio + Health’s first summit. Join Marc and Vijay as they talk about how AI can save the world, and where it can go wrong. Additional reading: Why AI Will Save the Wo…
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Meta’s primary Twitter competitor Threads earned more than 100 million downloads in its first five days - but what are the three key components required for the platform’s long-term success? On today’s episode, Jamie and Josh discuss the factors that led to the platform’s successful launch, how trust and safety protocols gave it an edge, and if Thr…
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How can we be critical of fear-based AI hype cycles? OpenAI CEO Sam Altman recently made headlines when he issued a 22-word statement warning of extinction due to the threats posed by AI - but what is Altman referring to, and what did he omit from his argument? This week, Jamie and Josh offer a critical discourse about the current AI hype cycle, th…
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In this flashback episode from 2020, Henry Cavill gets his geek on, talking everything from LORD OF THE RINGS and THE WITCHER to Superman. SUPPORT OUR SPONSORS RocketMoney -- Go to RocketMoney.com/HSC To watch episodes of Happy Sad Confused, subscribe to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Josh's youtube channel here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠! Check out the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Happy Sad …
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James Mangold joins Josh to talk about taking on Indiana Jones in INDIANA JONES & THE DIAL OF DESTINY, plus updates on his upcoming Bob Dylan film with Timothee Chalamet, a STAR WARS movie, and SWAMP THING! To watch episodes of Happy Sad Confused, subscribe to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Josh's youtube channel here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠! Check out the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Happ…
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AI is not just a sci-fi concept anymore; it's being woven into the fabric of healthcare, revolutionizing everything from research to patient care. It has the potential to create more streamlined and efficient processes. The challenge now is how we adapt and regulate this ever-evolving technology, while ensuring safety and trust. Amy Abernethy, form…
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Bryan Cranston reflects on his career, from his humble beginnings to BREAKING BAD to Broadway, and now ASTEROID CITY. SUPPORT THE SHOW BY SUPPORTING OUR SPONSORS! HelloFresh -- Go to ⁠HelloFresh.com/HSC16⁠ for 16 free meals plus free shipping! To watch episodes of Happy Sad Confused, subscribe to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Josh's youtube channel here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠…
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In this episode, taken from a live a16z event, Bio + Health general partner Vineeta Agarwala moderates a panel of UCSF faculty founders, including Michelle Arkin, Jimmie Ye, and Natalia Jura (full bios below). Together, they discuss fundraising, the decision to stay in or leave academia after founding a company, and their tips for managing the IP p…
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(recorded prior to the strike) THE LAST OF US showrunner Craig Mazin joins Josh for a deep dive into the remarkable first season of the show and gives a tease of what's to come. #happysadconfused #joshhorowitz #craigmazin #thelastofus SUPPORT THE SHOW BY SUPPORTING OUR SPONSORS! HelloFresh -- Go to HelloFresh.com/HSC16 for 16 free meals plus free s…
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Get ready for a wild live taping of the podcast with the cast of OUTLANDER! What's in store for season 7 and the end of OUTLANDER, plus games and tons of laughs. #happysadconfused #joshhorowitz #outlander #samheughan #caitrionabalfe #sophieskelton #richardrankin SUPPORT THE SHOW BY SUPPORTING OUR SPONSORS! ZocDoc -- Go to Zocdoc.com/HAPPYSAD and do…
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Today’s episode is with Mark Cuban, founder of multiple businesses, owner of the Dallas Mavericks, one of the sharks on Shark Tank, and cofounder of the Mark Cuban Cost Plus Drug Company. He is joined by Vijay Pande, founding partner of a16z Bio + Health. Together, they talk market forces in healthcare, the importance of trust to patients, and Mark…
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What does it mean to be a rebel in a digital age? PEN Award-winning author Mitch Horowitz provides us with three strategies to move forward. Recorded live at Digital Void's Meme in the Moment Festival in New York City on Wednesday, October 26, 2022. 🎟️ You can see Mitch and an incredible lineup of speakers including Shannon Liao, Allegra Frank, Dou…
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Today’s episode is a cross-post with the a16z podcast. It features founders—Chris Severn, Florian Otto, Andrew Adams, Jade Chan, Jimmy Chen, and Fay Rotenberg—chatting with a16z podcast host Steph Smith, about how they're trying to reinvent the healthcare system, using fintech. Additional reading: https://a16z.com/healthcare-meets-fintech/ https://…
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It's been a good year for Meghann Fahy and she's on the podcast to talk all about it! THE WHITE LOTUS, meeting Taylor Swift, and more! #happysadconfused #joshhorowitz #thewhitelotus #theboldtype UPCOMING LIVE EVENTS! ⁠⁠Bryan Cranston -- 6/16 at 92NY in NYC. Virtual tickets available. ⁠⁠Get your tickets here! ⁠⁠ To watch episodes of Happy Sad Confus…
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Josh Wolfe co-founded Lux Capital to support scientists and entrepreneurs who pursue counter-conventional solutions to the most vexing puzzles of our time in order to lead us into a brighter future. The more ambitious the project, the better—like, say, creating matter from light. Wolfe is a director at Shapeways, Strateos, Lux Research, Kallyope, C…
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Josh Wolfe co-founded Lux Capital to support scientists and entrepreneurs who pursue counter-conventional solutions to the most vexing puzzles of our time in order to lead us into a brighter future. The more ambitious the project, the better—like, say, creating matter from light. Wolfe is a director at Shapeways, Strateos, Lux Research, Kallyope, C…
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