Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
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The Optispan Podcast with Matt Kaeberlein
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Optispan is a vision for what health should be. The typical person gives up 10-20 years of quality life in exchange for disability, frailty, and early death. We call this "the lost decade". Time that should be spent with loved ones doing the activities you enjoy are instead spent suffering from multiple diseases and taking a cabinet full of medications that probably do as much harm as good. We believe that the current practice of medicine is disease care, not health care. We believe that everyone can get closer to their own optimal healthspan.
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Optispan is a vision for what health should be. The typical person gives up 10-20 years of quality life in exchange for disability, frailty, and early death. We call this "the lost decade". Time that should be spent with loved ones doing the activities you enjoy are instead spent suffering from multiple diseases and taking a cabinet full of medications that probably do as much harm as good. We believe that the current practice of medicine is disease care, not health care. We believe that everyone can get closer to their own optimal healthspan.
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The Optispan Podcast with Matt Kaeberlein
1 LiveLong Conference: Takeaways on Longevity Science & Hype | 113 29:51
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Play Later Play Later Lists Like LikedSubscribe to our channel: https://www.youtube.com/@optispanGet Our Newsletter (It's Free): https://www.optispan.life/Matt Kaeberlein & Dr. Kevin White share takeaways from the LiveLong Experience conference, covering Therapeutic Plasma Exchange (TPE) insights, Hormone Replacement Therapy (HRT) debates, longevity science, and navigating misinformation vs. fact.0:00 Intro: LiveLong Conference Vibe & Overview2:35 NHL, TBI & Psychedelics (Daniel Carcillo Talk)5:34 Therapeutic Plasma Exchange (TPE) Insights & Interest12:34 Concerns: Sirtuins & Resveratrol Misinformation15:01 Highlights: Vonda Wright & Hormone Replacement Discussion15:32 Concerns: Debunking HRT Misinformation (Michael Greger Talk)18:01 Critique: The Need for Debate & Clarity at Conferences20:40 ConsumerLab & The Vitamin D Debate (Todd Cooperman Talk)24:23 Questioning Causality: Cancer Risk Claims (HLI Talk)28:57 Overall Impressions & Final ThoughtsProduction: Tara Mei, Nicholas Arapis, https://videocastproductions.comDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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The Optispan Podcast with Matt Kaeberlein
1 This Simple Test Can Reveal Your Risk Of Heart Disease | 112 40:16
40:16 Play Later Play Later Lists Like Liked40:16
Play Later Play Later Lists Like LikedSubscribe to our channel: https://www.youtube.com/@optispanGet Our Newsletter (It's Free): https://www.optispan.life/Matt Kaeberlein reviews his personal Cleerly CCTA scan results with Prime Health Associates founder Dr. Kevin White, analyzing soft vs. calcified heart plaque, assessing cardiovascular risk, and discussing the value of early detection for longevity.0:00 Intro: What is a Cleerly CCTA Scan?1:31 Why Scan? The Value of Early Heart Disease Detection3:49 The Scan Experience (Prep, Contrast, Process)5:20 Radiation & Contrast Concerns Explained8:53 Analyzing Results: Overall Plaque Burden (% Atheroma)14:08 Plaque Types: Soft vs. Calcified & Low-Density16:55 Understanding Stenosis (% Blockage)18:14 CAD-RADS Score Explained20:11 Visualizing the Plaque: Interactive Scan Tour24:12 Actionability: Staging Risk & What To Do NextProduction: Tara Mei, Nicholas Arapis, https://videocastproductions.comDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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The Optispan Podcast with Matt Kaeberlein
1 The Hidden Health Toll Of Grief (and the 4 Tasks that Actually Work). | Emma Payne | 111 1:13:17
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Play Later Play Later Lists Like LikedSubscribe to our channel: https://www.youtube.com/@optispanGet Our Newsletter (It's Free): https://www.optispan.life/Help Texts CEO Emma Payne discusses the profound impact of grief on health (physical/mental), effective coping strategies (Warden's Tasks), and how text-based support can help navigate loss and foster post-traumatic growth.0:00 Intro: Grief's Impact on Health & Biology1:12 Defining Grief: Lost Connection & Blunt Force Trauma2:55 How Grief Disrupts the Pillars of Health4:12 The Social Isolation of Grief & Why Support Falters12:00 Warden's Tasks of Mourning: A Framework for Coping25:58 Beyond Death: Disenfranchised Grief (Jobs, Pets, etc.)37:01 Post-Traumatic Growth: Finding Strength After Loss43:06 Help Texts Explained: Text-Based Grief Support44:48 The Origin Story of Help Texts1:09:39 How to Effectively Support Someone GrievingProduction: Tara Mei, Nicholas Arapis, https://videocastproductions.comDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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The Optispan Podcast with Matt Kaeberlein
1 Rapamycin: The Worst Longevity Idea Ever Conceived? | 110 43:04
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Play Later Play Later Lists Like LikedSubscribe to our channel: https://www.youtube.com/@optispanGet Our Newsletter: https://www.optispan.life/Dr. Matt Kaeberlein fact-checks Dr. Chris Masterjohn's essay calling rapamycin the "Worst Longevity Idea Ever," correcting misinformation about side effects (cataracts, glucose, heart) and benefits using scientific data from mouse and human studies.0:00 Intro: Tackling the "Worst Longevity Idea Ever" Essay1:06 Who is Dr. Chris Masterjohn? Expertise Questioned3:20 Debunking Mouse Claims: Cataracts, Testicular Atrophy, Glucose Metabolism12:45 Fact Check: Rapamycin's Impact on Health Span (Benefits Ignored)17:02 mTOR, Fasting Cycles & Flawed Nutrient Signaling Arguments23:26 Debunking Claims: Heart Scarring, Fatty Liver, Shrinking Testicles27:28 Dose Comparisons, Marmoset Data & Keeping Up With Science31:27 Misleading Comparisons: Organ Transplant vs. Off-Label Use33:44 Correcting Claims on Testosterone, Wound Healing & Oral Inflammation36:55 The Real Rapamycin Data, Safety Profile & Final ThoughtsProduction: Tara Mei, Nicholas Arapis, https://videocastproductions.comDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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The Optispan Podcast with Matt Kaeberlein
1 Siim Land: Biohacking Longevity, Health Span Truths & Cutting Through the Hype | 109 1:18:28
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Play Later Play Later Lists Like LikedSubscribe to our channel: https://www.youtube.com/@optispanBiohacking expert Siim Land joins Matt Kaeberlein to discuss optimizing health span with science-based lifestyle tips (diet, exercise, sleep), key biomarkers, and navigating longevity misinformation & biological age clock hype.0:00 Introduction: Meet Siim Land2:41 Defining Longevity: Health Span vs Lifespan4:31 The Longevity Escape Velocity Debate12:21 Navigating Longevity Hype, Misinformation & Credibility28:56 Biohacking Case Study: Creatine Megadose Experiment35:02 Essential Biomarkers for Health Span (Bloodwork, DEXA, Imaging)44:24 Optimizing Exercise: Cardio, Strength, Intensity & Overtraining52:20 Diet Deep Dive: Calories, Quality, Timing, Protein & Fiber1:03:16 Beyond Diet & Exercise: Sleep, Alcohol, Social Connection1:10:04 Biological Age Clocks: Useful Tool or Just Noise?Production: Tara Mei, Nicholas Arapis, https://videocastproductions.comDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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The Optispan Podcast with Matt Kaeberlein
1 The Science of Aging Well: "A Practical Approach to HealthSpan Medicine" | 108 16:12
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Play Later Play Later Lists Like LikedSubscribe to our channel: https://www.youtube.com/@optispanSign up for the Optispan Newsletter: https://www.optispan.life/Read or get your copy of Matt's Scientific American Article: https://www.scientificamerican.com/custom-media/healthspan/In this episode, Dr. Matt Kaeberlein reads and discusses his insightful article, "A Practical Approach to HealthSpan Medicine," featured in the Scientific American special issue "HealthSpan: The Science of Aging Well."Discover the future of healthcare focused on living well longer, not just living longer. This article delves into the principles of Health Span Medicine, a proactive approach prioritizing years lived in good health (healthspan) over sheer lifespan. Producers: Tara Mei, Nicholas ArapisVideo Editor: Jacob KeliikoaMore places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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The Optispan Podcast with Matt Kaeberlein
1 Longevity Experts Discuss Their Health Advice & Approach | Dr. Marcus Ranney & Dr. Brian Kennedy | 107 56:38
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Play Later Play Later Lists Like LikedSubscribe to our channel: https://www.youtube.com/@optispanDr. Matt Kaeberlein is joined by Dr. Marcus Ranney and Dr. Brian Kennedy, leading experts in longevity science. Recorded at the Rise for Aging Conference in Bangalore, India, they discuss India’s growing role in longevity research, the impact of AI in aging and healthcare, and unique health challenges in India, such as diet, diabetes, and metabolic health. They also explore innovative healthcare solutions, including digital health records, longevity clinics, AI-driven diagnostics, and personalized medicine. The conversation covers stem cell therapy, hormone replacement, key supplements, and lifestyle interventions for healthy aging.0:00 - Introduction & Overview of the Rise for Aging Conference2:00 - The Growth of India's Longevity Science & Healthcare Innovation4:45 - Challenges & Opportunities in India's Healthcare System7:30 - AI & Technology Transforming Longevity Medicine10:00 - Stem Cells, Safety Concerns & Potential Benefits15:00 - The Role of Peptides & NAD in Aging22:00 - Lifestyle Interventions: Exercise, Diet & Sleep for Longevity30:00 - The Importance of Supplements, Hormones & Personalized Medicine40:00 - Cutting-Edge Diagnostics & The Future of Health Monitoring55:00 - Closing Thoughts & Final TakeawaysProducers: Tara Mei, Nicholas ArapisVideo Editor: Jacob KeliikoaDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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The Optispan Podcast with Matt Kaeberlein
1 Brain Aging & Alzheimer’s Prevention: The Future of Cognitive Health Testing | Dr. Christin Glorioso | 106 1:00:35
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Play Later Play Later Lists Like LikedSubscribe to our channel: https://www.youtube.com/@optispan Dr. Matt Kaeberlein & Dr. Christin Glorioso, founder of NeuroAge Therapeutics, explore groundbreaking advancements in brain aging and Alzheimer's prevention. Learn how cutting-edge brain age testing—combining MRI, cognitive assessments, blood biomarkers, and genetics—can predict Alzheimer’s risk decades in advance. Discover the impact of lifestyle factors like diet, exercise, and sleep on cognitive decline, plus the latest in medications, including GLP-1 agonists and hormone replacement therapy. 0:00 - Introduction to NeuroAge & Brain Aging2:50 - Understanding the Brain Age Clock & Alzheimer's Risk6:30 - The Role of Genetics in Brain Aging10:15 - How MRI Scans Measure Brain Health14:40 - Cognitive Testing & Neuro Games Explained19:10 - The Impact of Lifestyle on Brain Aging24:55 - Medications & New Alzheimer’s Treatments29:40 - The Potential of GLP-1 Agonists & Hormone Therapy36:15 - Challenges of Direct-to-Consumer Brain Age Testing48:30 - Final Thoughts on Cognitive Health & Future Research Producers: Tara Mei, Nicholas ArapisVideo Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. More places to find us: Twitter: https://twitter.com/optispanpodcast Twitter: https://twitter.com/optispan Twitter: https://twitter.com/mkaeberlein Linkedin: https://www.linkedin.com/company/optispan Instagram: https://www.instagram.com/optispanpodcast/ TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/ Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it. On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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The Optispan Podcast with Matt Kaeberlein
1 Gut Health: Science-Backed Tips For Leaky Gut, IBS, & Your Microbiome | Dr. Mary Pardee | 105 1:15:32
1:15:32 Play Later Play Later Lists Like Liked1:15:32
Play Later Play Later Lists Like LikedSubscribe to our channel: https://www.youtube.com/@optispanDr. Matt Kaeberlein & Dr. Mary Pardee sit down to discuss insights on gut health, digestion, and common GI issues like IBS and constipation. This video covers practical approaches to improving gut function, debunking myths, and identifying effective solutions for long-term wellness, all while attempting to separate fact from fiction in the world of gut health.0:00 - Introduction to Gut Health & Microbiome1:47 - IBS and Digestive Health: How It's Diagnosed & Treated3:04 - The Truth About Microbiome Testing: Myths vs. Science6:36 - FDA & Direct-to-Consumer Microbiome Tests: Are They Reliable?11:44 - Probiotics: Do They Work & Who Should Take Them?16:05 - IBS Treatment: Lifestyle, Diet, and Medications24:26 - Diets & Gut Health: Keto, Carnivore, & Plant-Based Comparisons32:04 - Supplements for Gut Health: What Works & What’s Overhyped?56:26 - Cardiovascular Screening: Coronary Calcium Score vs. Clearly Scan1:12:32 - Supplements: What’s Worth Taking & What’s a Waste of Money?Producers: Tara Mei, Nicholas ArapisVideo Editor: Jacob KeliikoaDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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The Optispan Podcast with Matt Kaeberlein
Subscribe to our channel: https://www.youtube.com/@optispanMatt Kaeberlein dives into the controversial world of biological age tests. Many direct-to-consumer tests claim to measure your biological age, but are they accurate or useful? Based on extensive research and clinical experience, we uncover why these tests are statistically meaningless, lack regulatory validation, and fail to provide actionable health insights. Instead, we highlight proven biomarkers that actually contribute to longevity and well-being. If you're considering spending money on a biological age test, watch this first!In this episode of the Optisan Podcast, we dive into the controversial world of biological age tests. Many direct-to-consumer tests claim to measure your biological age, but are they accurate or useful? Based on extensive research and clinical experience, we uncover why these tests are statistically meaningless, lack regulatory validation, and fail to provide actionable health insights. Instead, we highlight proven biomarkers that actually contribute to longevity and well-being. If you're considering spending money on a biological age test, watch this first!0:00 - Introduction & Overview1:09 - Why Biological Age Tests Are Misleading2:26 - Optisan’s Research on Biological Age Tests4:40 - Understanding Biological Age Clocks & Their Limitations6:34 - The Four Major Problems with These Tests7:57 - Lack of Regulatory Approval & Oversight10:28 - Are Doctors Benefiting from These Tests?12:22 - Reliable Biomarkers for Longevity & HealthProducers: Tara Mei, Nicholas ArapisVideo Editor: Jacob KeliikoaDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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The Optispan Podcast with Matt Kaeberlein
1 Dr. Kevin White: Concierge Medicine & Its Impacts On Living Longer & Healthier Lives | 103 50:54
50:54 Play Later Play Later Lists Like Liked50:54
Play Later Play Later Lists Like LikedSubscribe to our channel: https://www.youtube.com/@optispan In this episode, we dive into concierge medicine, how it differs from traditional primary care, and why more people are opting for personalized healthcare. Dr. Kevin White shares insights on longevity medicine, proactive health strategies, and the benefits of direct physician access. We discuss the costs, the role of insurance, advanced diagnostics, and the future of AI in concierge medicine. 0:00 - Intro & Concierge Medicine Overview3:15 - How Concierge Medicine Differs from Primary Care9:40 - Benefits of Personalized Doctor Access15:20 - Costs, Insurance, & Payment Options21:05 - Longevity & Proactive Health Strategies28:35 - Advanced Testing & Diagnostics in Concierge Care35:50 - AI & Technology in Concierge Medicine42:10 - How to Find a Good Concierge Doctor Producers: Tara Mei, Nicholas ArapisVideo Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. More places to find us: Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispan https://www.optispan.life/ Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it. On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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The Optispan Podcast with Matt Kaeberlein
1 Thomas Delauer: NEW Nutrition, Exercise, and Mindset Shifts In 2025 | 102 42:42
42:42 Play Later Play Later Lists Like Liked42:42
Play Later Play Later Lists Like LikedSubscribe to our channel: https://www.youtube.com/@optispanThomas DeLauer & I (Dr. Matt Kaeberlein) discusses his evolving perspectives on nutrition, exercise, and health optimization. Thomas shares how his views on insulin, low-carb diets, and fructose have shifted, his approach to training for strength and longevity, and the importance of sleep, emotional well-being, and recovery. Delauer also touches on peptides, supplements, and wearable tech, providing valuable takeaways for those looking to improve their performance, body composition, and overall health.0:00 - Introduction & Thomas DeLauer’s evolving views2:10 - The challenge of simplifying health content4:57 - Shifting perspectives on nutrition & health goals7:55 - Low-carb lifestyle & insulin reconsidered12:49 - A day in the life: Diet, fasting & protein intake19:04 - Strength training, cardio & hybrid workouts25:45 - Sleep optimization & recovery strategies30:11 - Emotional health, connection & mindfulness36:02 - Peptides, supplements & risk vs. rewardProducers: Tara Mei, Nicholas ArapisVideo Editor: Jacob KeliikoaDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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The Optispan Podcast with Matt Kaeberlein
1 My Biggest Health & Longevity Breakthroughs at 54 | 101 21:21
21:21 Play Later Play Later Lists Like Liked21:21
Play Later Play Later Lists Like LikedSubscribe to our channel: https://www.youtube.com/@optispanI share the top health and longevity strategies that have transformed my energy, fitness, and well-being at 54 - From hormone optimization (TRT) and resistance training to diet improvements, alcohol reduction, and preventative diagnostics.0:00 - Reflections on Turning 54 & Longevity Mindset1:42 - Hormone Optimization: The Biggest Game-Changer3:28 - Diet & Alcohol Reduction: Key Health Improvements4:56 - Exercise & Resistance Training for Longevity9:10 - Preventative Diagnostics & Biomarkers Matter16:46 - Relationships & Mental Well-Being in HealthProducers: Tara Mei, Nicholas ArapisVideo Editor: Jacob KeliikoaDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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The Optispan Podcast with Matt Kaeberlein
1 Dr. Greg Fahy: Thymus Regeneration & Boosting The Immune System For Longevity | 100 1:31:13
1:31:13 Play Later Play Later Lists Like Liked1:31:13
Play Later Play Later Lists Like LikedSubscribe to our channel: https://www.youtube.com/@optispanDr. Greg Fahy discusses his groundbreaking research on thymus regeneration, immune system rejuvenation, and the role of growth hormone, DHEA, and metformin in reversing aging-related immune decline. He explains the TRIM protocol, the impact of thymic involution on longevity, and the potential for improving vaccine response and overall health. This conversation explores immune function, senescent cell clearance, and epigenetic aging clocks.0:00 - Introduction & Guest Introduction2:05 - The Origins of the TRIM Protocol6:30 - Growth Hormone & Thymus Regeneration in Rats12:40 - Growth Hormone, Insulin Resistance & DHEA20:10 - Why Thymus Regeneration Matters for Longevity27:50 - Thymic Involution & Its Role in Aging35:45 - Measuring Thymic Function & Immune Rejuvenation42:15 - Rapamycin, Thymus, and Immune System Enhancement50:20 - Human Trials: Thymus Regeneration & Exercise Performance1:03:00 - The Future of Anti-Aging & Immune RestorationProducers: Tara Mei, Nicholas ArapisVideo Editor: Jacob KeliikoaDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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The Optispan Podcast with Matt Kaeberlein
1 The Benefits Of Testosterone Replacement Therapy (TRT) For Men - Dr. Kevin White | 99 58:44
58:44 Play Later Play Later Lists Like Liked58:44
Play Later Play Later Lists Like LikedSubscribe to our channel: https://www.youtube.com/@optispanIs testosterone therapy right for you? In this episode, Matt Kaeberlein & Kevin White explore the benefits, risks, and misconceptions of testosterone replacement therapy (TRT). Learn about low testosterone symptoms, when to get tested, and the differences between primary and secondary hypogonadism. We also cover treatment options like injections, creams, and Clomid, plus the impact on heart health, longevity, and mental well-being.0:00 - Introduction to Testosterone Therapy1:25 - The Gradual Decline of Testosterone in Men3:35 - Symptoms and When to Get Tested6:00 - Primary vs. Secondary Hypogonadism Explained10:34 - Common Misconceptions About Testosterone Therapy19:07 - Different Treatment Options: Injections, Creams, and More24:41 - Addressing Risks: Cancer, Mood, and Heart Health32:20 - Can Testosterone Therapy Improve Longevity?39:02 - Mental Health & Quality of Life Benefits51:14 - How Many Men Actually Need Testosterone Therapy?Producers: Tara Mei, Nicholas ArapisVideo Editor: Jacob KeliikoaDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!…
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