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Cannabis Nutrigenomics: How Your Genes Affect Your High | David Krantz ~ ATTMind 111
Manage episode 246726522 series 1440089
David Krantz and I talk about how genetics affect the metabolism of cannabis (nutrigenomics) and the resulting impact of cannabis use on our epigenetic health. Furthermore, we reach into a discussion on how the same framework of understanding applies to our metabolism of psychedelics and the potential future of a genome-specific screening program for psychedelic-assisted psychotherapy.
--LINKS-- For links to David's work, full show notes, and to watch this episode in video, head to Https://bit.ly/ATTMind111 **Full Topics Breakdown Below --- SUPPORT THIS PODCAST — Patreon: https://patreon.com/jameswjesso Donations: https://www.paypal.me/JWJesso Merchandise: https://www.jameswjesso.com/shop/ More options: https://www.jameswjesso.com/support/ Sponsor: FORMULA Nootropics https://www.jameswjesso.com/formula Use promo code "jesso" to get 20% off your first order. Newsletter: https://www.jameswjesso.com/newsletter ------------- Episode Breakdown- a general rundown of nutritional genomics and its application in understanding biology
- the profound health issues David faced that brought him into nutritional genomics
- (special note about the value of understanding polyvagal theory)
- the failure of the pre-packed dietary approach, be it veganism, paleo, or low-carb
- the endocannabinoid system
- the genetic differences of cannabis metabolism between different people
- why some people can “smoke weed every day” and make millions, and others can’t get off the couch
- how cannabis effects working memory differently in different genetic predispositions in each people based on baseline dopamine levels
- how our brain hides from itself
- the phenomena of “used to smoke all the time without issues then all of a sudden cannabis creates anxiety and paranoia”
- epigenetics and how cannabis changes how our genes express
- the genetic variant that increases the chances of developing cannabis-induced psychosis
- genetic profiling as a screening platform to understand what medical intervention would be most helpful for specific people
- the institutional complications that might prevent the introduction of genetic-specific medical care into the medical infrastructure
- how these ideas fit inside the modern context of the climate crisis
- how do genetic profiles influence dose-response differences with psychedelics
- speculating on the long term epigenetic impact of psilocybin use
- speculating on the long term epigenetic impact of therapeutic/healing work
----------
*** Big thanks to my patrons on Pateron for helping keep this podcast alive! Especially, Thomas & Melanie H, Clea S, Steven B, James R, Dean H, Joe A, Andy D, Stephen B, Ian C, David W, Don J, Yvett FC, Ann-Madeleine, Dima B, Chuck W & Cornelius Phlegmbottom
---------
--- SUPPORT THIS PODCAST — Patreon: https://patreon.com/jameswjesso Donations: https://www.paypal.me/JWJesso Merchandise: https://www.jameswjesso.com/shop/ More options: https://www.jameswjesso.com/support/ Sponsor: FORMULA Nootropics https://www.jameswjesso.com/formula Use promo code "jesso" to get 20% off your first order. Newsletter: https://www.jameswjesso.com/newsletter --- BOOKS — Decomposing The Shadow: https://www.jameswjesso.com/decomposing-the-shadow/ The True Light Of Darkness: https://www.jameswjesso.com/true-light-darkness/ --- LINKS — Website: https://www.jameswjesso.com/ Speaking Tour: https://www.jameswjesso.com/events/ Podcast: https://www.jameswjesso.com/podcast/ Twitter: https://twitter.com/jameswjesso Instagram: https://www.instagram.com/attmindpodcast/ Facebook: https://www.facebook.com/jameswjesso --- PRODUCTS — Art: https://www.jameswjesso.com/product-category/art/ Teeshirts: https://www.jameswjesso.com/product-category/clothing/ Lectures: https://www.jameswjesso.com/product/psychedelics-ritualistic-suffering-and-the-meaning-of-life-lecture/
212 episodes
Manage episode 246726522 series 1440089
David Krantz and I talk about how genetics affect the metabolism of cannabis (nutrigenomics) and the resulting impact of cannabis use on our epigenetic health. Furthermore, we reach into a discussion on how the same framework of understanding applies to our metabolism of psychedelics and the potential future of a genome-specific screening program for psychedelic-assisted psychotherapy.
--LINKS-- For links to David's work, full show notes, and to watch this episode in video, head to Https://bit.ly/ATTMind111 **Full Topics Breakdown Below --- SUPPORT THIS PODCAST — Patreon: https://patreon.com/jameswjesso Donations: https://www.paypal.me/JWJesso Merchandise: https://www.jameswjesso.com/shop/ More options: https://www.jameswjesso.com/support/ Sponsor: FORMULA Nootropics https://www.jameswjesso.com/formula Use promo code "jesso" to get 20% off your first order. Newsletter: https://www.jameswjesso.com/newsletter ------------- Episode Breakdown- a general rundown of nutritional genomics and its application in understanding biology
- the profound health issues David faced that brought him into nutritional genomics
- (special note about the value of understanding polyvagal theory)
- the failure of the pre-packed dietary approach, be it veganism, paleo, or low-carb
- the endocannabinoid system
- the genetic differences of cannabis metabolism between different people
- why some people can “smoke weed every day” and make millions, and others can’t get off the couch
- how cannabis effects working memory differently in different genetic predispositions in each people based on baseline dopamine levels
- how our brain hides from itself
- the phenomena of “used to smoke all the time without issues then all of a sudden cannabis creates anxiety and paranoia”
- epigenetics and how cannabis changes how our genes express
- the genetic variant that increases the chances of developing cannabis-induced psychosis
- genetic profiling as a screening platform to understand what medical intervention would be most helpful for specific people
- the institutional complications that might prevent the introduction of genetic-specific medical care into the medical infrastructure
- how these ideas fit inside the modern context of the climate crisis
- how do genetic profiles influence dose-response differences with psychedelics
- speculating on the long term epigenetic impact of psilocybin use
- speculating on the long term epigenetic impact of therapeutic/healing work
----------
*** Big thanks to my patrons on Pateron for helping keep this podcast alive! Especially, Thomas & Melanie H, Clea S, Steven B, James R, Dean H, Joe A, Andy D, Stephen B, Ian C, David W, Don J, Yvett FC, Ann-Madeleine, Dima B, Chuck W & Cornelius Phlegmbottom
---------
--- SUPPORT THIS PODCAST — Patreon: https://patreon.com/jameswjesso Donations: https://www.paypal.me/JWJesso Merchandise: https://www.jameswjesso.com/shop/ More options: https://www.jameswjesso.com/support/ Sponsor: FORMULA Nootropics https://www.jameswjesso.com/formula Use promo code "jesso" to get 20% off your first order. Newsletter: https://www.jameswjesso.com/newsletter --- BOOKS — Decomposing The Shadow: https://www.jameswjesso.com/decomposing-the-shadow/ The True Light Of Darkness: https://www.jameswjesso.com/true-light-darkness/ --- LINKS — Website: https://www.jameswjesso.com/ Speaking Tour: https://www.jameswjesso.com/events/ Podcast: https://www.jameswjesso.com/podcast/ Twitter: https://twitter.com/jameswjesso Instagram: https://www.instagram.com/attmindpodcast/ Facebook: https://www.facebook.com/jameswjesso --- PRODUCTS — Art: https://www.jameswjesso.com/product-category/art/ Teeshirts: https://www.jameswjesso.com/product-category/clothing/ Lectures: https://www.jameswjesso.com/product/psychedelics-ritualistic-suffering-and-the-meaning-of-life-lecture/
212 episodes
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