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Authentic Biochemistry Podcast. Alzheimer’s Disease coda. Dr Daniel J Guerra.04sept24

1:20:08
 
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Manage episode 438231971 series 3137613
Content provided by Dr Daniel J. Guerra. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr Daniel J. Guerra or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Correction:

In my lecture I incorrectly used the W single letter designation as representing tyrosine. I miss-spoke.

W=tryptophan while Y=tyrosine.

The WW domain discussion is important for specific protein:protein interactions wherein the tryptophan (W) residues (found in the beta1 and beta 3 folds) are separated by 20 -22 amino acids that contain certain tyrosine (Y) residues in the beta2 region which may become phosphorylated thus generating phosophotyrosine binding (PTB)domains that are recognized by other proteins.

I apologize for the error.

References

Exp Biol Med (Maywood). 2015 Mar; 240(3):375–382

Cellular Physiology and Biochemistry (2017) 41 (3): 1189–1198.

PNAS 2022 Sep6;119(36):e2204069119

Alzheimer's Research & Therapy.2024.volume 16, Article number: 144 Joel, B. 1977. Vienna [Strangers;lp]

https://open.spotify.com/track/4U45aEWtQhrm8A5mxPaFZ7?si=240c0d811f164b7c

Beethoven, LV. 1816. Seventh Symphony A major. Op92.

https://open.spotify.com/album/2kDHEJxutXleLTNCctvgSB?si=qefvirqXSviiOqPmvWME7w

--- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  continue reading

805 episodes

Artwork
iconShare
 
Manage episode 438231971 series 3137613
Content provided by Dr Daniel J. Guerra. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr Daniel J. Guerra or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Correction:

In my lecture I incorrectly used the W single letter designation as representing tyrosine. I miss-spoke.

W=tryptophan while Y=tyrosine.

The WW domain discussion is important for specific protein:protein interactions wherein the tryptophan (W) residues (found in the beta1 and beta 3 folds) are separated by 20 -22 amino acids that contain certain tyrosine (Y) residues in the beta2 region which may become phosphorylated thus generating phosophotyrosine binding (PTB)domains that are recognized by other proteins.

I apologize for the error.

References

Exp Biol Med (Maywood). 2015 Mar; 240(3):375–382

Cellular Physiology and Biochemistry (2017) 41 (3): 1189–1198.

PNAS 2022 Sep6;119(36):e2204069119

Alzheimer's Research & Therapy.2024.volume 16, Article number: 144 Joel, B. 1977. Vienna [Strangers;lp]

https://open.spotify.com/track/4U45aEWtQhrm8A5mxPaFZ7?si=240c0d811f164b7c

Beethoven, LV. 1816. Seventh Symphony A major. Op92.

https://open.spotify.com/album/2kDHEJxutXleLTNCctvgSB?si=qefvirqXSviiOqPmvWME7w

--- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

  continue reading

805 episodes

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