Can cell therapy tackle hearing loss?

Beyond Biotech - the podcast from Labiotech

Hearing loss is a huge – and growing – global challenge.

Using its OSPREY platform, UK-based Rinri Therapeutics is developing a portfolio of off-the-shelf regenerative cell therapy products to address sensorineural hearing loss, a significant global medical challenge.

The company’s lead asset, Rincell-1, is designed to regenerate auditory neurons and provide a novel treatment for patients with severe-to-profound age-related hearing loss or auditory neuropathy. The company is looking to start first-in-human trials in 2025.

Today, on the podcast we have a conversation with Rinri CEO Simon Chandler about the different kinds of hearing loss, what’s being done to tackle them, and Rinri’s novel approach to treatments.

01:08-03:19: About Rinri Therapeutics
03:19-05:16: About hearing loss
05:16-07:31: Mental health and hearing loss
07:31-10:22: The different kinds of hearing loss
10:22-11:37: The importance of early intervention
11:37-13:46: What is Rinri doing to tackle hearing loss?
13:46-15:58: The difficulty of accessing the cochlea
15:58-19:12: Is your treatment a cure for hearing loss?
19:12-20:45: Would repeat treatment be necessary?
20:45-23:30: Are other companies working on hearing loss?
23:30-25:27: The cost of treating hearing loss
25:27-27:13: The economic costs of hearing loss
27:13-28:33: Rinri treatment timelines
28:33-30:15: The rest of Rinri’s pipeline
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Chapters

1. Can cell therapy tackle hearing loss? (00:00:00)

2. About Rinri Therapeutics
 (00:01:08)

3. About hearing loss (00:03:19)

4. Mental health and hearing loss
 (00:05:16)

5. The different kinds of hearing loss (00:07:31)

6. The importance of early intervention
 (00:10:22)

7. What is Rinri doing to tackle hearing loss?
 (00:11:37)

8. The difficulty of accessing the cochlea
 (00:13:46)

9. Is your treatment a cure for hearing loss?
 (00:15:58)

10. Would repeat treatment be necessary?
 (00:19:12)

11. Are other companies working on hearing loss?
 (00:20:45)

12. The cost of treating hearing loss
 (00:23:30)

13. The economic costs of hearing loss
 (00:25:27)

14. Rinri treatment timelines
 (00:27:13)

15. The rest of Rinri’s pipeline
 (00:28:33)