New ways to treat Duchenne muscular dystrophy

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Duchenne muscular dystrophy (DMD) is a genetic disorder with progressive muscle degeneration and weakness due to changes in the protein dystrophin, which helps keep muscle cells intact.

There are few treatments for DMD, although recent advances mean that males – who are primarily affected by DMD – can now sometimes survive into their 30s.
More drugs are being developed in the fight against DMD, and this week we had a conversation with Frank Gleeson, CEO of Satellos Bioscience, about recent work on addressing DMD, including the company’s own work in the field.

00:47-02:01: About Satellos Bioscience
02:01-04:33: What is Duchenne muscular dystrophy?
04:33-05:43: What are the challenges in treating Duchenne muscular dystrophy?
05:43-09:08: What are the new treatments for Duchenne muscular dystrophy?
09:08-11:20: What is your treatment for Duchenne muscular dystrophy?
11:20-13:42: Are there different approaches to treating Duchenne muscular dystrophy?
13:42-14:06: How is your treatment delivered?
14:06-17:32: How important is early intervention?
17:32-18:56: Where is Satellos at with clinical trials?
18:56-20:41: Preclinical trial results
20:41-21:44: Outreach to the Duchenne muscular dystrophy community
21:44-23:12: Is a cure for Duchenne muscular dystrophy possible?

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Chapters

1. New ways to treat Duchenne muscular dystrophy (00:00:00)

2. About Satellos Bioscience (00:00:47)

3. What is Duchenne muscular dystrophy?  (00:02:01)

4. What are the challenges in treating Duchenne muscular dystrophy?  (00:04:33)

5. What are the new treatments for Duchenne muscular dystrophy? (00:05:43)

6. What is your treatment for Duchenne muscular dystrophy?  (00:09:08)

7. Are there different approaches to treating Duchenne muscular dystrophy?  (00:11:20)

8. How is your treatment delivered? (00:13:42)

9. How important is early intervention? (00:14:06)

10. Where is Satellos at with clinical trials?  (00:17:32)

11. Preclinical trial results  (00:18:56)

12. Outreach to the Duchenne muscular dystrophy community  (00:20:41)

13. Is a cure for Duchenne muscular dystrophy possible? (00:21:44)

104 episodes

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