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biosights: March 6, 2017

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Manage episode 198086804 series 2045212
Content provided by Rockefeller University Press and The Rockefeller University Press. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Rockefeller University Press and The Rockefeller University Press or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Actin isoforms divide their responsibilities in motoneurons

Actin dynamics are crucial for axon growth and branching, but most studies have only focused on the role of β-actin. Moradi et al. reveal that α-, β-, and γ-actin have different functions in motoneuron axons; locally translated α-actin forms stable actin filaments that promote the formation of axonal branches, whereas β-actin regulates growth cone dynamics. This biosights episode presents the paper by Moradi et al. from the March 6th, 2017, issue of The Journal of Cell Biology and includes an interview with the paper's senior author, Michael Sendtner (University Hospital Würzburg, Würzburg, Germany). Produced by Caitlin Sedwick and Ben Short. See the associated paper in JCB for details on the funding provided to support this original research.

Subscribe to biosights via iTunes or RSS View biosights archive

The Rockefeller University Press biosights@rockefeller.edu

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119 episodes

Artwork

biosights: March 6, 2017

biosights

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Manage episode 198086804 series 2045212
Content provided by Rockefeller University Press and The Rockefeller University Press. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Rockefeller University Press and The Rockefeller University Press or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Actin isoforms divide their responsibilities in motoneurons

Actin dynamics are crucial for axon growth and branching, but most studies have only focused on the role of β-actin. Moradi et al. reveal that α-, β-, and γ-actin have different functions in motoneuron axons; locally translated α-actin forms stable actin filaments that promote the formation of axonal branches, whereas β-actin regulates growth cone dynamics. This biosights episode presents the paper by Moradi et al. from the March 6th, 2017, issue of The Journal of Cell Biology and includes an interview with the paper's senior author, Michael Sendtner (University Hospital Würzburg, Würzburg, Germany). Produced by Caitlin Sedwick and Ben Short. See the associated paper in JCB for details on the funding provided to support this original research.

Subscribe to biosights via iTunes or RSS View biosights archive

The Rockefeller University Press biosights@rockefeller.edu

  continue reading

119 episodes

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