The Outer Limits 1963 s2 e 15 The Brain Of Colonel Barham

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The space race continues as the American military strives to be the first to successfully land a man on Mars. But the best candidate for the job, Col. Barham, is dying of an incurable ailment that has left him unable to walk. There is great debate whether a human being could survive a trip to Mars and whether a computer could adapt to unforeseen circumstances. It is decided to separate the Colonel's brain from his body and keep it alive, with neural implants connecting it to visual and audio input/output for the mission combining an astronaut's brain with a computer. But without a body, the brain becomes extremely powerful and develops megalomaniacal tendencies that endanger the life of his wife and others.