#177 — Psychedelic Science

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By Waking Up with Sam Harris and Sam Harris. Discovered by Player FM and our community — copyright is owned by the publisher, not Player FM, and audio is streamed directly from their servers. Hit the Subscribe button to track updates in Player FM, or paste the feed URL into other podcast apps.

In this episode of the Making Sense podcast, Sam Harris speaks with Roland Griffiths about the current state of research on psychedelics. They discuss the historical prohibition against their use; the clinical and scientific promise of psilocybin, mescaline, LSD, DMT, MDMA, and other compounds; the risks associated with these drugs; the role of “set and setting”; the differences between psychedelics and drugs of abuse; MDMA and neurotoxicity; experiences of unity, sacredness, love, and truth; the long-term consequences of psychedelic experiences; synthetic vs natural drugs; the prospects of devising new psychedelics; microdosing; research on psilocybin and long-term meditators; the experience of encountering other apparent beings; psilocybin treatment of addiction; and other topics. In his Afterword, Sam discusses his experience on a large dose of psilocybin—his first psychedelic experience in 25 years.

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