#25 - Calcium, zinc, IL-6 - do we know how they fit into our athletes nutrition and performance?

Medical Sports Nutrition

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In short - no. But we review a series of recent articles trying to pick away at the inner workings of these markers. We try and avoid the pitfalls of black and white answers and steer around the icebergs of simplification. In addition, beetroot and blood pressure, water use and ibuprofen on the intestine.
References:

Lundy B, McKay AKA, Fensham NC, Tee N, Anderson B, Morabito A, Ross MLR, Sim M, Ackerman KE, Burke LM. The Impact of Acute Calcium Intake on Bone Turnover Markers during a Training Day in Elite Male Rowers. Med Sci Sports Exerc. 2023 Jan 1;55(1):55-65. doi: 10.1249/MSS.0000000000003022. Epub 2022 Aug 12. PMID: 35977107; PMCID: PMC9770130.

McKenna ZJ, Ducharme JB, Berkemeier QN, Specht JW, Fennel ZJ, Gillum TL, Deyhle MR, Amorim FT, Mermier CM. Ibuprofen Increases Markers of Intestinal Barrier Injury But Suppresses Inflammation at Rest and After Exercise in Hypoxia. Med Sci Sports Exerc. 2023 Jan 1;55(1):141-150. doi: 10.1249/MSS.0000000000003032. Epub 2022 Sep 5. PMID: 36069803.

Astridge DJ, Peeling P, Goods PSR, Girard O, Hewlett J, Rice AJ, Binnie MJ. Rowing in Los Angeles: Performance Considerations for the Change to 1500 m at the 2028 Olympic Games. Int J Sports Physiol Perform. 2022 Nov 29;18(1):104-107. doi: 10.1123/ijspp.2022-0231. PMID: 36448487.

Burtscher J, Vanderriele PE, Legrand M, Predel HG, Niebauer J, O'Keefe JH, Millet GP, Burtscher M. Could Repeated Cardio-Renal Injury Trigger Late Cardiovascular Sequelae in Extreme Endurance Athletes? Sports Med. 2022 Dec;52(12):2821-2836. doi: 10.1007/s40279-022-01734-8. Epub 2022 Jul 18. PMID: 35851948; PMCID: PMC9691495.

Nash D, Hughes MG, Butcher L, Aicheler R, Smith P, Cullen T, Webb R. IL-6 signaling in acute exercise and chronic training: Potential consequences for health and athletic performance. Scand J Med Sci Sports. 2023 Jan;33(1):4-19. doi: 10.1111/sms.14241. Epub 2022 Oct 8. PMID: 36168944.

Rogerson D, Aguilar Mora FA, Young JS, Klonizakis M. No effect of nitrate-rich beetroot juice on microvascular function and blood pressure in younger and older individuals: a randomised, placebo-controlled double-blind pilot study. Eur J Clin Nutr. 2022 Oct;76(10):1380-1386. doi: 10.1038/s41430-022-01115-4. Epub 2022 Mar 29. PMID: 35352014; PMCID: PMC9550618.

Toro-Román V, Siquier-Coll J, Bartolomé I, Grijota FJ, Muñoz D, Maynar-Mariño M. Influence of physical training on intracellular and extracellular z

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