PT Inquest is an online journal club. Hosted by Jason Tuori, Megan Graham, and Chris Juneau, the show looks at an article every week and discusses how it applies to current physical therapy practice.
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Manage episode 291740446 series 2516105
Content provided by Monash University - Department of Anaesthesiology and Perioperative Medicine., Monash University - Department of Anaesthesiology, and Perioperative Medicine.. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Monash University - Department of Anaesthesiology and Perioperative Medicine., Monash University - Department of Anaesthesiology, and Perioperative Medicine. or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
Dexamethasone is widely used by anaesthetists in the perioperative period, principally as an effective antiemetic to prevent postoperative nausea and vomiting (PONV). The molecular mechanisms underlying dexamethasone’s antiemetic action are not fully understood. However, because it is a potent glucocorticosteroid, it is has immunosuppressive and hyperglycaemia effects. It is hypothesised that these actions may increase the risk of perioperative infections, particularly in patients with diabetes mellitus, who are already at increased risk of complications. Whether the use of dexamethasone in the perioperative period increases the risk of surgical site and other infections, has not been definitively established. This is an important health priority as in Australia alone up to one million patients will receive dexamethasone as part of their anaesthesia care annually. This study aims to definitively address the impact of dexamethasone on surgical site infection and will be stratified according to diabetes status.
…
continue reading
49 episodes
MP3•Episode home
Manage episode 291740446 series 2516105
Content provided by Monash University - Department of Anaesthesiology and Perioperative Medicine., Monash University - Department of Anaesthesiology, and Perioperative Medicine.. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Monash University - Department of Anaesthesiology and Perioperative Medicine., Monash University - Department of Anaesthesiology, and Perioperative Medicine. or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
Dexamethasone is widely used by anaesthetists in the perioperative period, principally as an effective antiemetic to prevent postoperative nausea and vomiting (PONV). The molecular mechanisms underlying dexamethasone’s antiemetic action are not fully understood. However, because it is a potent glucocorticosteroid, it is has immunosuppressive and hyperglycaemia effects. It is hypothesised that these actions may increase the risk of perioperative infections, particularly in patients with diabetes mellitus, who are already at increased risk of complications. Whether the use of dexamethasone in the perioperative period increases the risk of surgical site and other infections, has not been definitively established. This is an important health priority as in Australia alone up to one million patients will receive dexamethasone as part of their anaesthesia care annually. This study aims to definitively address the impact of dexamethasone on surgical site infection and will be stratified according to diabetes status.
…
continue reading
49 episodes
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