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Episode 11: Talking to Dr. Danielle Pretorius about Fabricating cardiac tissue patches

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Manage episode 292307861 series 2924942
Content provided by Alicia Botes and Jacob Schekman, Alicia Botes, and Jacob Schekman. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Alicia Botes and Jacob Schekman, Alicia Botes, and Jacob Schekman or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Dr. Danielle Pretorius has earned her PhD in Biomedical Engineering at the University of Alabama at Birmingham. Together with Dr. Jay Zhang, she is helping to fabricate cardiac tissue patches that is made from human-induced pluripotent stem cell-derived cells. The initial structures were made with fibrin but due to the dynamic nature of the cells, the extracellular matrix of these cells could be remodeled. Danielle and her group's fabrications process has allowed them to achieve previously unseen tissue thickness with minimal necrosis, the ability to match viscoelasticity properties to those seen in native left ventricular tissue as well as phenomenal conduction velocities throughout the structures.

You can find out more about Dr. Pretorius and her work in this link:

https://www.linkedin.com/in/dani%C3%ABlle-pretorius-b93280b5/

Thank you for listening!

Please feel free to contact us at the email below:

polymersciencepodcast@gmail.com

  continue reading

42 episodes

Artwork
iconShare
 
Manage episode 292307861 series 2924942
Content provided by Alicia Botes and Jacob Schekman, Alicia Botes, and Jacob Schekman. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Alicia Botes and Jacob Schekman, Alicia Botes, and Jacob Schekman or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Dr. Danielle Pretorius has earned her PhD in Biomedical Engineering at the University of Alabama at Birmingham. Together with Dr. Jay Zhang, she is helping to fabricate cardiac tissue patches that is made from human-induced pluripotent stem cell-derived cells. The initial structures were made with fibrin but due to the dynamic nature of the cells, the extracellular matrix of these cells could be remodeled. Danielle and her group's fabrications process has allowed them to achieve previously unseen tissue thickness with minimal necrosis, the ability to match viscoelasticity properties to those seen in native left ventricular tissue as well as phenomenal conduction velocities throughout the structures.

You can find out more about Dr. Pretorius and her work in this link:

https://www.linkedin.com/in/dani%C3%ABlle-pretorius-b93280b5/

Thank you for listening!

Please feel free to contact us at the email below:

polymersciencepodcast@gmail.com

  continue reading

42 episodes

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