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Ep. 58: “Redesigning Proteins” Featuring Dr. Jamie Spangler

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Content provided by The Immunology Podcast. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by The Immunology Podcast or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Jamie Spangler

Guest:

Dr. Jamie Spangler is an Assistant Professor at Johns Hopkins. Her lab implements a unique structure-based engineering approach to elucidate the determinants of protein activity and inform drug development. She talks about designing cytokine mimetics and how engineered cytokines could be used as therapeutics.

Featured Products and Resources:

The Immunology Science Round Up

Microenvironment Reprogramming in Cancer Progression – Researchers developed a high-resolution tumor microenvironment atlas for gastric adenocarcinoma.

Tregs and Cell Therapy for Parkinson’s Disease – Co-transplanting Tregs with iPSC-derived neurons improves cell survival.

How Hepatitis C Hides from the Immune System – Flavin adenine dinucleotide capping of the hepatitis C virus protects RNA from RIG-I mediated innate immune recognition.

Mast Cells in Antigen-Avoidance – Mast cell activation in the stomach lining releases leukotrienes to affect food avoidance behavior.

Allergic Responses and Behavior Modification – Researchers showed that allergic sensitization drives antigen-specific avoidance behavior in mouse models of food allergy.

Image courtesy of Dr. Jamie Spangler

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111 episodes

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Fetch error

Hmmm there seems to be a problem fetching this series right now. Last successful fetch was on October 30, 2024 01:18 (4d ago)

What now? This series will be checked again in the next day. If you believe it should be working, please verify the publisher's feed link below is valid and includes actual episode links. You can contact support to request the feed be immediately fetched.

Manage episode 371624848 series 2895470
Content provided by The Immunology Podcast. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by The Immunology Podcast or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Jamie Spangler

Guest:

Dr. Jamie Spangler is an Assistant Professor at Johns Hopkins. Her lab implements a unique structure-based engineering approach to elucidate the determinants of protein activity and inform drug development. She talks about designing cytokine mimetics and how engineered cytokines could be used as therapeutics.

Featured Products and Resources:

The Immunology Science Round Up

Microenvironment Reprogramming in Cancer Progression – Researchers developed a high-resolution tumor microenvironment atlas for gastric adenocarcinoma.

Tregs and Cell Therapy for Parkinson’s Disease – Co-transplanting Tregs with iPSC-derived neurons improves cell survival.

How Hepatitis C Hides from the Immune System – Flavin adenine dinucleotide capping of the hepatitis C virus protects RNA from RIG-I mediated innate immune recognition.

Mast Cells in Antigen-Avoidance – Mast cell activation in the stomach lining releases leukotrienes to affect food avoidance behavior.

Allergic Responses and Behavior Modification – Researchers showed that allergic sensitization drives antigen-specific avoidance behavior in mouse models of food allergy.

Image courtesy of Dr. Jamie Spangler

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