Ep 9: Sex Differences in Hypertension: Pharmacological Treatment

The Radcliffe Cardiology Podcast

In the first of a three-part ECR Podcast series on hypertension in women, Dr Isabella Sudano (University Hospital and University of Zurich, Zurich, CH) and Dr Eva Gerdts (Haukeland University Hospital, Bergen, NO) are joined by Prof Juan Tamargo (University Complutense, Madrid, ES) to discuss pharmalogical treatment options and considerations. Discussion points for this episode include: Are there differences in the effect of antihypertensive treatment between women and men? Why do women more often report adverse events of diuretics, beta-blockers, CCB, and ACEi? Swedish registries have reported differences in prescriptions for women and men with hypertension. Women are more often prescribed diuretics, and men are more often ACEI. Is there a rationale for this? Sex-specific analysis of drug effects has only been reported in a few clinical trials. Are such analyses important and what is the knowledge today? Should we consider choosing the dose of antihypertensive drugs according to sex? If you have any questions or suggestions, please email [e-mail].