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Episode 1: Pete Kirkpatrick, mRNA therapeutics and Espresso Martinis
Manage episode 392966082 series 3545167
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Pete Kirkpatrick, Chief Editor of Nature Reviews Drug Discovery, gives Andy and JC the lowdown on a Nature Conference on RNA therapeutics and what innovations he is seeing in the field of mRNA therapies.
01:44 Nature conference on RNA therapies
08:11 Differences between mRNA therapeutics and mRNA vaccines
14:24 mRNA chemistries
18:08 mRNA manufacturing
22:05 mRNA delivery
27:21 Delivering LNPs to organs other than liver
34:25 Targeting RNA with small molecules
39:35 RNA-guided CRISPR, base and prime editing therapies
48:35 Pete’s tipple
Pete's tipple of choice:
Expresso Martini
1.5 Oz vodka, 1 Oz coffee liqueur, 1.5 Oz espresso.
Shake over large ice cubes for 10-12 sec and strain into a Martini glass.
Garnish with roasted coffee beans.
(N.B. Ideally, 1.5 Oz of espresso should come from ~20 g of ground coffee.)
The Mixer music “Pour Me Another” courtesy of Smooth Moves!
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