Concise summaries of everything published in the latest weekly issue of the New England Journal of Medicine (NEJM). NEJM publishes new medical research findings, review articles, and editorial opinion on topics of importance to biomedical science and clinical practice.
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Insightful conversations with leading experts in the field of health care, medical research, policy, and more from the New England Journal of Medicine (NEJM). Each episode examines the many complexities found at the junction of medicine and society.
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NEJM AI Grand Rounds, hosted by Arjun (Raj) Manrai, Ph.D. and Andrew Beam, Ph.D., features informal conversations with a variety of unique experts exploring the deep issues at the intersection of artificial intelligence, machine learning, and medicine. You’ll learn how AI will change clinical practice and healthcare, how it will impact the patient experience, and about the people who are pushing for innovation. Whether you are an AI researcher or a practicing clinician, these conversations w ...
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Audio podcasts featuring the week’s top medical news plus pertinent interviews
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The House reflects medicine’s most pressing issues through the eyes of residents, providing a forum to share their stories from the bedside, where they are learning far more than the lessons of clinical medicine.
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A Day in the Life is a podcast for medical students, by medical students. Interviews with attendings about daily life and training may help you explore a range of specialties.
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NEJM Interview: Revati Masilamani on a multitiered mentoring program aimed at supporting pathways to biomedical careers for students from diverse backgrounds.
12:46
12:46
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12:46
Revati Masilamani is an assistant professor of medical education at Tufts University School of Medicine. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J.A. Caro and Others. A Multitiered Mentorship Model — Fostering Inclusive Pathways to Health Careers. N Engl J Med 2024;391:675-676.…
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Featuring articles on amino acid infusion and kidney protection, azithromycin to reduce childhood mortality in Niger, belzutifan in renal-cell carcinoma, and a transfusion strategy in traumatic brain injury; a review article on sexual dysfunction in women; a case report of a woman with aphasia, anemia, and a breast mass; and Perspectives on a serie…
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From Petri Dishes to Pitch Decks: Cultivating Health Care’s AI Future with Vijay Pande
54:08
54:08
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54:08
In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Dr. Vijay Pande, a general partner at Andreessen Horowitz (A16Z) where he leads investments in health care and life sciences. The conversation explores Pande’s journey from academia to venture capital, his views on the future of AI in health care and biomedicine, and …
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NEJM Interview: Barron Lerner on challenges to physician expertise and restoring trust in the medical profession.
7:49
7:49
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Barron Lerner is a professor in the Departments of Medicine and Population Health at New York University Grossman School of Medicine. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. B.H. Lerner. Medical Expertise — Balancing Science, Values, and Trust. N Engl J Med 2024;391:577-579.…
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Featuring articles on osimertinib in stage III EGFR-mutated lung cancer, cognitive motor dissociation in disorders of consciousness, rapid deployment of a brain–computer interface in ALS, and the longevity of a brain–computer interface for ALS; a review article on the genetics of chronic kidney disease; a case report of a boy with autism and decrea…
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NEJM Interview: Gregg Gonsalves on the Covid pandemic’s lessons for addressing H5N1 influenza and other infectious threats.
7:38
7:38
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Gregg Gonsalves is an associate professor of epidemiology at the Yale School of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. M.S. Sinha, W.E. Parmet, and G.S. Gonsalves. Déjà Vu All Over Again — Refusing to Learn the Lessons of Covid-19. N Engl J Med 2024;391:481-483.…
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Featuring articles on crinecerfont in pediatric and adult congenital adrenal hyperplasia, the postacute sequelae of SARS-CoV-2 infection, and nipocalimab in early-onset severe hemolytic disease of the fetus and newborn; a review article on frailty in older adults; a case report of a woman with postpartum anxiety and intrusive thoughts; and Perspect…
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Featuring articles on belantamab mafodotin for multiple myeloma, autoantibodies targeting nephrin in podocytopathies, neutralizing anti–interleukin-10 autoantibodies in IBD; a review article on Parkinson’s disease; a Clinical Problem-Solving on going down the rabbit hole; a Medicine and Society article on race-based screening under the ethics micro…
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NEJM Interview: Elizabeth Tobin-Tyler on the contribution of violence against women to unwanted pregnancies and to injury and death during the peripartum period.
11:27
11:27
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Elizabeth Tobin-Tyler is an associate professor at the Brown University School of Public Health and Warren Alpert Medical School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E. Tobin-Tyler and S.L. Dickman. Rape, Homicide, and Abortion Bans — The Abandonment of People Subjected to Sexual and Intimate Partner…
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Featuring articles on treatments for metabolic dysfunction–associated steatohepatitis, blinatumomab in adults with ALL, and sotorasib for KRAS G12C–driven vascular malformations; a review article on HIV-associated tuberculosis; a case report of a woman with rapidly progressive dementia; and Perspectives on the abandonment of people subjected to sex…
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NEJM Interview: Ida Sim on the translation of ethical principles into oversight of new forms of artificial intelligence.
14:24
14:24
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14:24
Ida Sim is a professor of medicine at the University of California, San Francisco, and codirector of the Joint Program in Computational Precision Health at UC Berkeley and UCSF. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. I. Sim and C. Cassel. The Ethics of Relational AI — Expanding and Implementing the Belm…
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Featuring articles on tenecteplase for ischemic stroke within 4.5 to 24 hours after the stroke, risankizumab vs. ustekinumab for Crohn’s disease, nirmatrelvir–ritonavir as Covid-19 postexposure prophylaxis, and efanesoctocog alfa in children with hemophilia A; a review article on the management of insomnia; a case report of a woman with postpartum …
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Love and Large Language Models: Voices of the Future with Dr. Rohaid Ali and Dr. Fatima Mirza
1:01:24
1:01:24
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In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Dr. Rohaid Ali and Dr. Fatima Mirza, a married couple and chief residents at Brown University. The conversation explores their innovative work applying AI to health care, focusing on two major projects: Using ChatGPT to simplify surgical consent forms, making them mor…
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NEJM Interview: Erin Fuse Brown on a vertical-consolidation trend that has given insurance companies increased control over the care-delivery system.
10:55
10:55
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10:55
Erin Fuse Brown is a professor of health services, policy, and practice at the Brown University School of Public Health and a member of the Journal’s Perspective Advisory Board. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. H. Rooke-Ley, S. Shah, and E.C. Fuse Brown. Medicare Advantage and Consolidation’s New …
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Featuring articles on semaglutide and chronic kidney disease in type 2 diabetes, felzartamab in kidney-transplant rejection, bulevirtide and peginterferon for chronic hepatitis D, and nirsevimab and hospitalization for RSV bronchiolitis; a review article on malnutrition in adults; a case report of an infant with vomiting and hypercalcemia; and Pers…
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NEJM Interview: Evan Mullen on academic institutions’ participation in public debate, including in response to the opinions of their faculty members.
9:35
9:35
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9:35
Evan Mullen is a resident in the Department of Medicine at Stanford University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E. Mullen, E.J. Topol, and A. Verghese. Academic Freedom in America — In Support of Institutional Voices. N Engl J Med 2024;391:1-3.
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Featuring articles on stress ulcer prophylaxis during invasive mechanical ventilation, new therapies for hereditary angioedema, tissue factor–directed therapy in cervical cancer, and normalization of C1 inhibitor in a patient with hereditary angioedema; a review article on acute abdomen in the modern era; a Clinical Problem-Solving article on aggre…
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NEJM Interview: Nathaniel Chin on increases in the time and resources needed to diagnose and manage neurodegenerative diseases.
10:00
10:00
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10:00
Nathaniel Chin is an associate professor in the Division of Geriatrics and Gerontology and medical director of the Alzheimer's Disease Research Center at the University of Wisconsin School of Medicine and Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. N.A. Chin and C.M. Erickson. Alzheimer’s Dise…
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Featuring articles on treatments for eosinophilic esophagitis, reteplase versus alteplase for acute ischemic stroke, dupilumab for COPD with type 2 inflammation, and brigatinib in NF2-related schwannomatosis; a review article on amyloidosis; a case report of a man with recurrent fever and liver lesions; and Perspectives on Alzheimer’s disease, biom…
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NEJM Interview: Christine Grady on the ethical challenges associated with recent developments in research on brain diseases.
16:35
16:35
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16:35
Christine Grady is chief of the Department of Bioethics at the National Institutes of Health Clinical Center. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. S. Hendriks and C. Grady. Ethics and Highly Innovative Research on Brain Diseases. N Engl J Med 2024;390:2133-2136.…
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Featuring articles on combination therapy for diffuse large B-cell lymphoma, autosomal dominant Alzheimer’s disease, noninvasive ventilation for preoxygenation during emergency intubation, a novel anti-CD38 antibody in immune thrombocytopenia, and a glucose-responsive insulin for type 2 diabetes; a review article on congenital and acquired Chiari s…
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AI and the Evolution of Medical Thought with Dr. Adam Rodman
53:02
53:02
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53:02
In this episode of the AI Grand Rounds podcast, Dr. Adam Rodman shares his unique journey from a historian to a physician deeply interested in the intersection of medicine and artificial intelligence. He highlights his unconventional path, driven by an obsession with epistemology and nosology, and his early exposure to AI through historical referen…
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NEJM Interview: Jessica Lewis on a group prenatal care program aimed at improving maternal and infant health in diverse patient populations.
8:49
8:49
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8:49
Jessica Lewis is a research scientist at the Yale School of Medicine. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J.B. Lewis and J.R. Ickovics. Expect With Me — Group Prenatal Care to Reduce Disparities. N Engl J Med 2024;390:2039-2040.
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Featuring articles on T-cell cancer after CAR T-cell therapy, the early diagnosis and treatment of COPD and asthma, and the implications of race adjustment in lung-function equations; a review article on diets; a case report of a woman with the worst headache of her life; and Perspectives on efforts toward equity and on feeling guilty.…
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Featuring articles on neoadjuvant immunotherapy for dMMR colon cancer, TAVR in patients with a small aortic annulus, gene editing and retinal degeneration, and the genetic diagnosis of rare diseases; a review article on disorders of magnesium; a case report of a woman with metastatic breast cancer; and a Perspective on malicious midwives, fruitful …
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NEJM Interview: Katharine Silbaugh on an approach to tobacco regulation that involves banning the sale of nicotine products to anyone born after a certain date.
6:57
6:57
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6:57
Katharine Silbaugh is a professor at the Boston University School of Law. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. K. Silbaugh, L. Del Valle, and C. Robertson. Toward a Tobacco-free Generation — A Birth Date–Based Phaseout Approach. N Engl J Med 2024;390:1837-1839.…
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Featuring articles on aficamten for obstructive hypertrophic cardiomyopathy; early blood-pressure reduction in acute stroke; interferon-γ in autoimmune polyendocrine syndrome type 1; video laryngoscopy for intubation in neonates; hunger, thirst, and Buridan’s ass; and global health law for a safer and fairer world; a review article on medical AI an…
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