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The Story of the Synovium

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Manage episode 407440387 series 3560282
Content provided by Healio, Adam J. Brown, and MD. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Healio, Adam J. Brown, and MD or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

How is the synovial fluid produced? Who figured it out? It’s a ripping yarn involving corpses, cats, anti-hypertensives, steroids and streptococcus.

Brought to you by Tremfya.

  • Intro :11
  • Today’s episode :15
  • Synovium 101 :22
  • Overview of the synovium and synovial fluid 2:06
  • How they figured it out? Dr. Marian Ropes 5:37
  • Investigating synovial fluid 7:46
  • Cows experiment and where synovial fluid comes from 11:25
  • Clinical review of synovial fluid 14:57
  • What’s inside the fluid? 18:54
  • What makes up the fluid? 20:51
  • How do things get out of the synovium? 23:19
  • How are things absorbed into the synovium? 27:21
  • How well do steroids get picked up systemically? 29:39
  • Summary 32:30
  • Thank you 34:59

Disclosures: Brown reports no relevant financial disclosures.

We’d love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum

References:

Edwards JC. J Anat. 1994;184:493-501.

Rhinelander FW, et al. J Clin Invest. 1939;doi:10.1172/JCI101011.

Shaffer MF, et al. J Exp Med. 1939;doi:10.1084/jem.70.3.293.

Stout A, et al. PM R. 2019;doi:10.1002/pmrj.12042.

  continue reading

84 episodes

Artwork
iconShare
 
Manage episode 407440387 series 3560282
Content provided by Healio, Adam J. Brown, and MD. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Healio, Adam J. Brown, and MD or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

How is the synovial fluid produced? Who figured it out? It’s a ripping yarn involving corpses, cats, anti-hypertensives, steroids and streptococcus.

Brought to you by Tremfya.

  • Intro :11
  • Today’s episode :15
  • Synovium 101 :22
  • Overview of the synovium and synovial fluid 2:06
  • How they figured it out? Dr. Marian Ropes 5:37
  • Investigating synovial fluid 7:46
  • Cows experiment and where synovial fluid comes from 11:25
  • Clinical review of synovial fluid 14:57
  • What’s inside the fluid? 18:54
  • What makes up the fluid? 20:51
  • How do things get out of the synovium? 23:19
  • How are things absorbed into the synovium? 27:21
  • How well do steroids get picked up systemically? 29:39
  • Summary 32:30
  • Thank you 34:59

Disclosures: Brown reports no relevant financial disclosures.

We’d love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum

References:

Edwards JC. J Anat. 1994;184:493-501.

Rhinelander FW, et al. J Clin Invest. 1939;doi:10.1172/JCI101011.

Shaffer MF, et al. J Exp Med. 1939;doi:10.1084/jem.70.3.293.

Stout A, et al. PM R. 2019;doi:10.1002/pmrj.12042.

  continue reading

84 episodes

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