Artwork

Content provided by Healio, Adam J. Brown, and MD. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Healio, Adam J. Brown, and MD or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
Player FM - Podcast App
Go offline with the Player FM app!

The History of Cryoglobulinemic Vasculitis: Dry Humors, Part 3

38:13
 
Share
 

Manage episode 407440418 series 3560282
Content provided by Healio, Adam J. Brown, and MD. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Healio, Adam J. Brown, and MD or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

This episode explores the history of cryoglobulinemic vasculitis, from the first person who froze a tube of blood and noticed something strange happened, to the discovery of hepatitis C. We also throw in how the lab test for cryoglobulins is performed and some of the data we have on therapy.

Brought to you by GSK. Consider the long-term impact of disease activity, flares and corticosteroid use on patients with active SLE. Learn more now at treatfortodayandtomorrow.com

  • Intro :20
  • In this episode :45
  • How is this test done? 1:30
  • What is the first description of cryoglobulins? 4:15
  • The first time “cryoglobulins” is used 10:26
  • Hepatitis C is discovered and linked to cryoglobulinemia 16:28
  • What do we know about the pathophysiology? 19:38
  • Why does HCV do this? 22:12

Brought to you by GSK. Considering a treatment change for patients with active SLE? Learn about a treatment option for your patients at treatfortodayandtomorrow.com.

  • What’s in the blood as a result of immune complex? 24:52
  • What do we know about autoimmune diseases and the prevalence of cryoglobulins? 26:03
  • What about treatment? 28:25
  • Summary of this three-part series 36:16

Disclosure: Brown reports no relevant financial disclosures.

We’d love to hear from you! Send your comments/questions to rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum

References:

Brouet JC, et al. Am J Med. 1974;57:775-788.

Cacoub P, et al. Clin Gastroenterol Hepatol. 2019;17:518-526.

De Vita S, et al. Arthritis Rheum. 2012;64:843-853.

Fuentes A, et al. Curr Rheumatol Rep. 2019;21:doi:10.1007/s11926-019-0859-0.

Lerner AB, Watson CJ. Am J Med Sci. 1947;214:410-415.

Lospalluto J, et al. Am J Med. 1962;32:142-147.

Meltzer M, Franklin EC. Am J Med. 1966;40:828-836.

Pascual M, et al. J Infect Dis. 1990;162:569-570.

Ragab G, Hussein MA. J Adv Res. 2017;8:99-111.

Tzioufas AG, et al. Arthritis Rheum. 1986;29:1098-1104.

Wintrobe MM, Buell, MV. Bull. Johns Hopkins Hosp. 1933;52:156-165.

  continue reading

82 episodes

Artwork
iconShare
 
Manage episode 407440418 series 3560282
Content provided by Healio, Adam J. Brown, and MD. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Healio, Adam J. Brown, and MD or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

This episode explores the history of cryoglobulinemic vasculitis, from the first person who froze a tube of blood and noticed something strange happened, to the discovery of hepatitis C. We also throw in how the lab test for cryoglobulins is performed and some of the data we have on therapy.

Brought to you by GSK. Consider the long-term impact of disease activity, flares and corticosteroid use on patients with active SLE. Learn more now at treatfortodayandtomorrow.com

  • Intro :20
  • In this episode :45
  • How is this test done? 1:30
  • What is the first description of cryoglobulins? 4:15
  • The first time “cryoglobulins” is used 10:26
  • Hepatitis C is discovered and linked to cryoglobulinemia 16:28
  • What do we know about the pathophysiology? 19:38
  • Why does HCV do this? 22:12

Brought to you by GSK. Considering a treatment change for patients with active SLE? Learn about a treatment option for your patients at treatfortodayandtomorrow.com.

  • What’s in the blood as a result of immune complex? 24:52
  • What do we know about autoimmune diseases and the prevalence of cryoglobulins? 26:03
  • What about treatment? 28:25
  • Summary of this three-part series 36:16

Disclosure: Brown reports no relevant financial disclosures.

We’d love to hear from you! Send your comments/questions to rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum

References:

Brouet JC, et al. Am J Med. 1974;57:775-788.

Cacoub P, et al. Clin Gastroenterol Hepatol. 2019;17:518-526.

De Vita S, et al. Arthritis Rheum. 2012;64:843-853.

Fuentes A, et al. Curr Rheumatol Rep. 2019;21:doi:10.1007/s11926-019-0859-0.

Lerner AB, Watson CJ. Am J Med Sci. 1947;214:410-415.

Lospalluto J, et al. Am J Med. 1962;32:142-147.

Meltzer M, Franklin EC. Am J Med. 1966;40:828-836.

Pascual M, et al. J Infect Dis. 1990;162:569-570.

Ragab G, Hussein MA. J Adv Res. 2017;8:99-111.

Tzioufas AG, et al. Arthritis Rheum. 1986;29:1098-1104.

Wintrobe MM, Buell, MV. Bull. Johns Hopkins Hosp. 1933;52:156-165.

  continue reading

82 episodes

All episodes

×
 
Loading …

Welcome to Player FM!

Player FM is scanning the web for high-quality podcasts for you to enjoy right now. It's the best podcast app and works on Android, iPhone, and the web. Signup to sync subscriptions across devices.

 

Quick Reference Guide