Emergency Medicine Cases – Where the Experts Keep You in the Know. For show notes, quizzes, videos and more learning tools please visit emergencymedicinecases.com
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Urothelial Bladder Cancer | Oncology Today with Dr Neil Love: Clinical Update on the Current Management of Advanced Urothelial Bladder Cancer'
MP4•Episode home
Manage episode 424277651 series 2513286
Content provided by Dr Neil Love. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr Neil Love or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
Featuring perspectives from Dr Petros Grivas, including the following topics:
- Collaboration between urologists and medical oncologists for the management of urothelial bladder cancer (UBC) (0:00)
- Evolution of treatment modalities for non-muscle-invasive bladder cancer (NMIBC) (11:16)
- Perspective on recurrence mechanisms of NMIBC (22:21)
- Potential implications of circulating tumor DNA-based research in the management of bladder cancer (25:27)
- Importance of collaborative care for patients with bladder cancer (42:02)
- Frequency of HER2 expression and approach to HER2 testing for metastatic UBC (mUBC); activity of trastuzumab deruxtecan (T-DXd) in HER2-positive solid tumors (46:57)
- Monitoring and management of T-DXd-associated side effects (1:00:47)
- Efficacy and ongoing investigation of the HER2-targeted antibody-drug conjugate disitamab vedotin; other promising agents and strategies under investigation for mUBC (1:07:32)
- Results from the Phase III PROOF 302 trial of infigratinib versus placebo for patients with high-risk resected UBC with an FGFR3 genomic alteration (1:11:22)
- Potential association between intravesical bacillus Calmette-Guérin administration and lower risk of being diagnosed with Alzheimer’s disease in patients with bladder cancer; feasibility of internet-based, patient-driven germline genetic testing (1:16:12)
1337 episodes
MP4•Episode home
Manage episode 424277651 series 2513286
Content provided by Dr Neil Love. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr Neil Love or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
Featuring perspectives from Dr Petros Grivas, including the following topics:
- Collaboration between urologists and medical oncologists for the management of urothelial bladder cancer (UBC) (0:00)
- Evolution of treatment modalities for non-muscle-invasive bladder cancer (NMIBC) (11:16)
- Perspective on recurrence mechanisms of NMIBC (22:21)
- Potential implications of circulating tumor DNA-based research in the management of bladder cancer (25:27)
- Importance of collaborative care for patients with bladder cancer (42:02)
- Frequency of HER2 expression and approach to HER2 testing for metastatic UBC (mUBC); activity of trastuzumab deruxtecan (T-DXd) in HER2-positive solid tumors (46:57)
- Monitoring and management of T-DXd-associated side effects (1:00:47)
- Efficacy and ongoing investigation of the HER2-targeted antibody-drug conjugate disitamab vedotin; other promising agents and strategies under investigation for mUBC (1:07:32)
- Results from the Phase III PROOF 302 trial of infigratinib versus placebo for patients with high-risk resected UBC with an FGFR3 genomic alteration (1:11:22)
- Potential association between intravesical bacillus Calmette-Guérin administration and lower risk of being diagnosed with Alzheimer’s disease in patients with bladder cancer; feasibility of internet-based, patient-driven germline genetic testing (1:16:12)
1337 episodes
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