#26 - Flavonoids - good for ageing but not much evidence for athletes. Also - I'm not lazy coach, it's my microbiome.

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Firsty a smattering of proof that flavonoids are great for managing ageing changes, but still no good evidence they help our athletes perform any better. Then a nice microbiome paper that tells us why some mice seem to be lazier than others. Can we stretch this to human athletes? Also we ask where can we shoehorn in continuous glucose monitors - it looks fancy and must be useful for our patients....
Apologies for forgetting the name of a leading UK Medical Nutrition Academic - of course it was Prof T Spector.
References:

Parr EB, Kouw IWK, Wheeler MJ, Radford BE, Hall RC, Senden JM, Goessens JPB, van Loon LJC, Hawley JA. Eight-hour time-restricted eating does not lower daily myofibrillar protein synthesis rates: A randomized control trial. Obesity (Silver Spring). 2023 Feb;31 Suppl 1:116-126. doi: 10.1002/oby.23637. Epub 2022 Dec 22. PMID: 36546330.

Bowler AM, Whitfield J, Marshall L, Coffey VG, Burke LM, Cox GR. The Use of Continuous Glucose Monitors in Sport: Possible Applications and Considerations. Int J Sport Nutr Exerc Metab. 2022 Dec 26:1-12. doi: 10.1123/ijsnem.2022-0139. Epub ahead of print. PMID: 36572039.

Rendón MY, Dos Santos Scholz MB, Bragagnolo N. Physical characteristics of the paper filter and low cafestol content filter coffee brews. Food Res Int. 2018 Jun;108:280-285. doi: 10.1016/j.foodres.2018.03.041. Epub 2018 Mar 15. PMID: 29735059.

Safe S, Jayaraman A, Chapkin RS, Howard M, Mohankumar K, Shrestha R. Flavonoids: structure-function and mechanisms of action and opportunities for drug development. Toxicol Res. 2021 Jan 20;37(2):147-162. doi: 10.1007/s43188-020-00080-z. PMID: 33868973; PMCID: PMC8007671.

Ruiz-Iglesias P, Gorgori-González A, Massot-Cladera M, Castell M, Pérez-Cano FJ. Does Flavonoid Consumption Improve Exercise Performance? Is It Related to Changes in the Immune System and Inflammatory Biomarkers? A Systematic Review of Clinical Studies since 2005. Nutrients. 2021 Mar 30;13(4):1132. doi: 10.3390/nu13041132. PMID: 33808153; PMCID: PMC8065858.

Parmenter BH, Bondonno CP, Murray K, Schousboe JT, Croft K, Prince RL, Hodgson JM, Bondonno NP, Lewis JR. Higher Habitual Dietary Flavonoid Intake Associates With Less Extensive Abdominal Aortic Calcification in a Cohort of Older Women. Arterioscler Thromb Vasc Biol. 2022 Dec;42(12):1482-1494. doi: 10.1161/ATVBAHA.122.318408. Epub 2022 Nov 3. PMID: 36325901.

Holland TM, Agarwal P, Wang Y, Dhan

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