Evidence based hair is a weekly podcast hosted by Dr Jeff Donovan, a Canadian dermatologist and hair specialist. Each week, Dr. Donovan highlights recently published hair loss research from around the world.
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Topical JAK Inhibitors: How well do they work for FFA/LPP?
16:03
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Welcome back to the Evidence-Based Hair Podcast! This episode continues our June theme on JAK inhibitors, focusing on their topical use for treating frontal fibrosing alopecia (FFA) and lichen planopilaris (LPP). We'll delve into a groundbreaking study by Dr. Maryanne Senna and colleagues from Boston, examining the effectiveness and side effects of…
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Season 7, Episode 9: Exploring Topical JAK Inhibitors for Scarring Alopecia
16:03
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Welcome back to another episode of the Evidence-Based Hair Podcast. This week, we continue our June theme of JAK inhibitors, focusing on the use of topical JAK inhibitors for treating frontal fibrosing alopecia (FFA) and lichen planopilaris (LPP). In this episode, we delve into a significant study by Dr. Maryanne Senna and colleagues from Boston, e…
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Season 7, Episode 9: Baricitinib for Pediatric Alopecia Areata: Promising Results and Future Directions
12:37
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Welcome to another episode of the Evidence-Based Hair Podcast. In this episode, Dr. Donovan delves into an insightful study by Zhao and colleagues, published in the Journal of the European Academy of Dermatology and Venereology, titled "Baricitinib Therapy for Pediatric Patients with Severe Alopecia Areata." This episode continues the June series d…
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Season 7, Episode 8: Effectiveness of Generic Tofacitinib in Treating Alopecia Areata
19:45
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Welcome back to another episode of the Evidence-Based Hair Podcast! In this episode, we delve into a fascinating study on the use of generic tofacitinib for treating alopecia areata. This study, published in the Archives of Dermatologic Research, explores the effectiveness and safety of generic tofacitinib. With the recent availability of this cost…
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Season 7, Episode 7: Infectious Diseases and Vaccinations Among JAK Inhibitor Users
19:19
19:19
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In this June series of the podcast, we focus on JAK inhibitors. This episode kicks off with a detailed review of an Italian study published in Expert Opinion in Drug Safety, which examines the incidence and management of infections in patients with alopecia areata treated with JAK inhibitors. Dr. Donovan discusses the findings, emphasizing that abo…
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Season 7, Episode 6: Topical Minoxidil for Facial Hair Enhancement
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In this episode, Dr. Jeff Donovan, a dermatologist and hair loss specialist, examines the effect of topical minoxidil in enhancing beard hair growth in men Dr. Donovan focuses on a study published in Sage Open Medicine Case Reports titled, "Facial Hair Enhancement with Minoxidil and Off-Label Use". This study highlights the impact of using topical …
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Season 7, Episode 5: Alcohol Hangover and Hair Discoloration
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In this episode, we will dive into fascinating recent studies about the side effects of Minoxidil, a widely-known medication for hair loss treatment. This podcast highlights new research regarding what Dr. Donovan calls "the OMAHA effect" (ORAL MINOXIDIL ALCOHOL HANGOVER ASSOCIATION), the surprising association between oral minoxidil use and exacer…
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Season 7, Episode 4: Views of Dermatology Practitioners on Oral Minoxidil
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In this episode, we dive into a thought-provoking study by Sanfilippo and Friedman, "Survey of Dermatology Practitioners' Opinions and Prescribing Habits of Oral Minoxidil for the Treatment of Androgenetic Hair Loss". The study provides valuable insights into the perceptions of practitioners on oral minoxidil, an increasingly popular option for tre…
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Season 7, Episode 3: Oral vs Topical Minoxidil for Androgenetic Alopecia
24:54
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In this episode of the Evidence-Based Hair Podcast hair loss specialist Dr. Jeff Donovan breaks down the findings of a recent study comparing oral minoxidil and topical minoxidil in the treatment of male androgenetic alopecia. Published in JAMA Dermatology, the study challenged popular opinions by revealing similar performance between the two types…
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Season 7, Episode 2: Drug-Induced Alopecia Areata
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This episode is dedicated to a fascinating subject – drug-induced alopecia areata. In addition to genetic factors, alopecia areata is also influenced by environmental factors such as infections and medications. In this episode, Dr Donovan highlights two studies: “A Cross-Sectional Analysis of Medications Used by Patients Reporting Alopecia Areata o…
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Season 7, Episode 1: Unraveling the Link Between Dupilumab and Cutaneous T-Cell Lymphoma
20:13
20:13
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Welcome to a new episode of the Evidence-Based Hair Podcast, where we discuss some questions surrounding the relationship between dupilumab and lymphoma. This episode dives deep into a study by Hasan and colleagues that explores the fascinating and somewhat controversial relationship between Dupilumab, a drug often used to treat atopic dermatitis p…
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Top 20 Hair Research Studies of 2023
2:46:03
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This is a recording from the live webinar was conducted live December 13, 2023. This is an annual event that is held every year in mid-December celebrating the top hair research studies. DERMATOPATHOLOGY Douglas A et al. Scalp Biopsy Influences Diagnostic Accuracy and Treatment in Black Women with Alopecia: A Retrospective Study. J Am Acad Dermatol…
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Season 6, Episode 7 (JAK Inhibitors in Skin Disease - Risk of Cardiovascular Disease, Blood Clots, and Acne)
22:54
22:54
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The Evidence Based Hair podcast highlighs the latest research in hair loss. This episode addresses articles related to the risk of cardiovascular disease, blood clots and acne in dermatology patients using JAK inhibitors.By Dr Jeff Donovan
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Season 6, Episode 6 (Alopecia Areata Triggered by COVID19 Vaccination)
21:31
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STUDIES REFERENCED IN THIS EPISODE Pastukhova E et al. Alopecia Areata as a Sequela of COVID-19 Vaccination: A Systematic Review J Cutan Med Surg. 2023 Jan-Feb;27(1):64-65. Wang C-W et al. Clinical characteristics and immune profiles of patients with immune-mediated alopecia associated with COVID-19 vaccinations. Clin Immunol. 2023 Oct:255:109737. …
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Season 6, Episode 5 (COVID 19 Infection and the Risk of Autoimmune Disease)
18:23
18:23
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STUDIES REVIEWED THIS WEEK: Chang R et al. Risk of autoimmune diseases in patients with COVID-19: A retrospective cohort study. EClinicalMedicine. 2023 Feb;56:101783 Tesch F et al. Incident autoimmune diseases in association with SARS-CoV-2 infection: a matched cohort study. Clin Rheumatol. 2023 Oct;42(10):2905-2914. Lim SG et al. Autoimmune and Au…
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Season 6 Episode 4 (Baricitinib for CCCA, LED laser therapy for CCCA)
22:37
22:37
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STUDIES REFERENCED IN THIS EPISODE: Workman K and Kindred C (starts at 2:10). Hair regrowth in a patient with central centrifugal cicatricial alopecia after a 2-month trial of baricitinib. JAAD Case Rep. 2023 Jul 28:39:109-111. Cook M et al (starts at 12:07). Use of low-level light therapy in management of central centrifugal cicatricial alopecia: …
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Season 6, Episode3 (Effect of Oral Minoxidil on Blood Pressure, Oral Minoxidil Use in Patients with High Blood Pressure and Arrhythmia)
38:06
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ARTICLES COVERED THIS WEEK STUDY 1: Ong M et al (starts at 5:12). Low-dose oral minoxidil for androgenetic alopecia is not associated with clinically significant blood-pressure changes: a retrospective study. J Am Acad Dermatol. 2023 Oct 13:S0190-9622(23)02976-6. Sanabria et al. Prospective cardiovascular evaluation with 24-h Holter and 24-h ambula…
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Season 6, Episode 2 (A Closer Look at Randomized Controlled Trials and Real World Non RCT Data)
26:32
26:32
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ARTICLES REFERENCED IN THIS EPISODE Krauss A (starts at 12:44). Why all randomised controlled trials produce biased results. Ann Med. 2018 Jun;50(4):312-322. Van Noreen R (starts at 15:33). Medicine is plagued by untrustworthy clinical trials. How many studies are faked or flawed? Nature. 2023 Jul;619(7970):454-458. Listen at https://youtu.be/_QLvz…
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Season 6 Episode 1 (Baricitinib Response Timing, Real World Study of Baricitinib)
41:21
41:21
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Studies Referenced in This Episode: Season 6 Episode 1 King B et al (starts at 4:07). When to expect scalp hair regrowth during treatment of severe alopecia areata with baricitinib: insights from trajectories analyses of patients enrolled in two phase III trials. Br J Dermatol. 2023 Sep 14:ljad253. Gargiulo L et al (starts at 30:22). Effectiveness …
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Reminder of December 1, 2023 Deadline For Evidence Based Hair FellowshipTraining Program for Hair Loss Practitioners
12:09
12:09
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On August 1, 2023, Dr Donovan announced the long awaited start of the Evidence Based Hair Fellowship training program. This is an online (virtual) training program for practitioners that wish to develop expertise in hair loss. The program runs Jan 2024 to August 2025 and participants meet once weekly for a three hour period (either on a Wednesday o…
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Alopecia Areata Awareness Month - Recording from Sept 6 2023 Live Public Webinar
52:10
52:10
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Alopecia Areata Awareness Month - Recording from Sept 6 2023 Live Public Webinar hosted by Dr Donovan. Question 1 (starts at 3:50): Is the rate of alopecia areata going up ? Question 2 (starts at 7:45). What blood tests should be ordered for someone with alopecia areata? Question 3 (starts at 11:58). Do JAK inhibitors cure alopecia areata? Question…
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Season 5, Episode 6 (Selenium Toxicity, Alopecia Neoplastica, Lymphema Distichiasis Syndrome, Eyebrow Hypotrichosis, Seasonal Shedding)
1:01:20
1:01:20
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Season 5 Ep 6By Dr Jeff Donovan
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Season 5, Episode 5 (CCCA Prognosis, CCCA in Males, Anagen Hairs in LPP, EPDS and NMSC and FD in Females)
1:02:43
1:02:43
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STUDIES REFERENCED IN THIS EPISODE Onamusi T et al (starts at 8:58). Clinical factors and hair care practices influencing outcomes in central centrifugal cicatricial alopecia. Arch Dermatol Res. 2023 May 15. doi: 10.1007/s00403-023-02630-5. Online ahead of print. Erinolaoluwa F et al (starts at 11:59). Hair regrowth in 2 patients with recalcitrant …
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Season 5, Episode 4 (Switching JAK Inhibitors, Ritlecitinib in Adolescents, VTE Risk in AT/AU, Habit Replacement Therapy in TTM)
1:20:28
1:20:28
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STUDIES REFERENCE IN THE EPISODE SWITCHING FROM TOFACITINIB TO BARICITINIB Kazmi A et al (starts at 12:33). Switching between tofacitinib and baricitinib in alopecia areata: A review of clinical response. J Am Acad Dermatol. 2023 Apr 4;S0190-9622(23)00532-7. RITLECITINIB IN ADOLESCENTS Hordinsky M et al (starts at 21:31). Efficacy and safety of rit…
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Season 5, Episode 3 (Ranking of Finasteride and Minoxidil Protocols for FPHL, Follow up to New York Times Aug 2022 Article, Periorbital Edema from Oral Minoxidil, TE from Anticonvulsant Medications)
1:00:59
1:00:59
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Evidence Based Hair is a podcast that highlights new hair loss research from around the world. The first Monday of each month is dedicated to studies in androgenetic alopecia, telogen effluvium and traction alopecia. One can also listen to this podcast on a variety of podcast channels.By Dr Jeff Donovan
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Season 5, Episode 2 (CVG secondary to Psoriasis, Hair Loss from Temporal Lifts, Oral minoxidil Lung Disease, PTSD & Autoimmunity, Laser Hair Removal & Behcet’s)
1:09:51
1:09:51
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NON SCARRING ALOPECIA AFTER HYALURONIC ACID TEMPORAL LIFTING TECHNIQUES Landau M et al (starts at 9:05). Nonscarring alopecia after temporal lifting technique with dermal fillers. JAAD Case Rep. 2023 May 12;37:30-34 Coimbra D.D., and de Oliveira B.S (starts at 10:17). Supra-auricular lifting with fillers: new technique. J Cosmet Dermatol. 2016;8(4)…
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Season 5 Episode 1 (LPP Disease Associations, LPP & Thyroid, Side Effects of HCQ, Genetic Basis of Male FFA, FFA Prevalence/Incidence)
1:05:31
1:05:31
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DISEASE ASSOCIATIONS IN FRONTAL FIBROSING ALOPECIA Conic et al. Exploring the association between lichen planopilaris, cardiovascular and metabolic disorders. J Eur Acad Dermatol Venereol 2021 Nov;35(11):e826-e828. Joshi et al. Comorbidities associated with lichen planopilaris: a case-control study using the All of Us database. Int J Dermatol. 2022…
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Season 4, Episode 8 (Isotretinoin for SD, Iron Therapy, Memantine for TTM, Antifungal Resistance
1:08:51
1:08:51
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Season 4, Episode 8By Dr Jeff Donovan
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Season 4, Episode7 (Tinea with baricitinib, ADHD and AA, Upadacitinib for AA, Baricitinib 52 week data, micro needling for MPHL)
1:02:02
1:02:02
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Season 4, Episode 7 DataBy Dr Jeff Donovan
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Season 4, Episode 6 (Scalp Neuropathy in DMS, Scurvy, Cutaneous Pili Migrans, Quiz Case, Beethoven’s Hair)
1:14:13
1:14:13
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Season4, Episode 6By Dr Jeff Donovan
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Season 4, Episode 5 (Hair Loss after COIVD Vaccines, FD in DEB, New DSC ”CVG” Variants, DSC After HT, DLE to SLE Progression)
1:16:13
1:16:13
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Season 4, Episode 5By Dr Jeff Donovan
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Season 4, Episode 4 (COVID hair loss, TE from anti-CGRP migraine meds, tinea capitis, oral minoxidil for traction alopecia
1:15:20
1:15:20
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Season 4 Episode 4 COVID RELATED TE Michelini S et al. Telogen Effluvium in SARS-CoV-2 Infection: histological aspects. J Eur Acad Dermatol Venereol. 2023 Mar 8. M Alharbi et al. Telogen effluvium after COVID-19 vaccination among public in Saudi Arabia. J Family Med Prim Care. 2022 Oct;11(10):6056-6060. Tahmaz A et al. [The Evaluation of Long Coron…
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Season 4 Episode 3 (Spironolactone for FPHL, Oral Minoxidil for Nails, Histology of AA vs AGA, AAI, Work Productivity in AA)
1:29:40
1:29:40
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Season 4, Episode 3By Dr Jeff Donovan
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Season 4, Episode 2 (Scalp Bx for Black Women, Oral Minoxidil for Chemotherapy Hair Loss, Folliculotropic MF, Atrichia with Papular Lesions, MTX and Liver Fibrosis)
1:13:05
1:13:05
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STUDIES REFERENCED ROLE OF SCALP BIOPSIES IN BLACK WOMEN WITH HAIR LOSS Douglas A et al. Scalp Biopsy Influences Diagnostic Accuracy and Treatment in Black Women with Alopecia: A Retrospective Study. J Am Acad Dermatol. 2023 Jan 31;S0190-9622(23)00157-3. ORAL MINOXIDIL IN CHEMOTHERAPY RELATED HAIR LOSS Kang J et al. Efficacy of low-dose oral minoxi…
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Season 4, Episode 1 (HCQ and Retinopathy Risk, FD Microbiome, LDN for LPP, TNF Inhibitors for DSC)
1:28:55
1:28:55
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STUDIES REFERENCED PATHOLOGY OF NON SCARRING AND SCARRING ALOPECIA Amanda Araujo Dos Reis Botega et al. Scarring versus Non-Scarring Alopecia: An Interobserver Histopathological Reproducibility Study Skin Appendage Disord. 2023 Jan;9(1):34-41. doi: 10.1159/000526966. Epub 2022 Nov 25. HYDROXYCHLOROQUINE AND RETINOPATHY RISK Ronald B Melles RB et al…
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Season Finale (PART 2 of 2): Top 20 Hair Research Studies of 2022
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The season finale summarizes the top 20 studies of the 2022 calendar year. This episode addresses studies in hair shedding, scarring alopecia, seborrheic dermatitis and hair straighteners (studies 12 to 20). Studies 1 to 11 are found in Part 1 (season 3 episode 9) STUDIES IN HAIR SHEDDING/TELOGEN EFFLUVIUM/ COVID19 STUDY 12: Muller-Ramos P et al. P…
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Season Finale (PART 1 of 2): Top 20 Hair Research Studies of 2022
1:17:33
1:17:33
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The season finale summarizes the top 20 studies of the 2022 calendar year. This episode addresses studies in androgenetic alopecia and alopecia areata (studies 1 to 11). Studies 12 to 20 are found in Part 2 (season 3 episode 10) STUDIES IN FEMALE PATTERN HAIR LOSS AND MALE PATTERN HAIR LOSS STUDY 1: Qui Y et al. Systematic Review and Meta-analysis …
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Season 3, Episode 8 (Microneedling for AA, Periodontitis and AA Risk, Microneedling in AGA, Hair Loss in Transgender Patients)
52:46
52:46
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STUDIES REFERENCED ROLE OF CORTICOSTEROIDS IN THE JAK INHIBITOR ERA Licata G et al (starts at 7:21). Management of alopecia areata in JAK-inhibitors era: are systemic and topical corticosteroids still useful? Int J Dermatol. 2022 Nov 13. ALOPECIA AREATA AND PERIODONTITIS Kim JS et al (starts at 17:15). Periodontitis and risk of alopecia areata: A n…
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Season 3, Episode 7 (Scalp Biopsies, Chronic Hives from Laser Hair Removal, Hair Pigmentation from Nilotinib, Sebderm & Osteoporosis, Finasteride and Bladder Ca)
1:00:49
1:00:49
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A mix of recently published studies in hair loss IRON PILL GASTRITIS Koch R et al (starts at5 5:19). Case report: Rapid onset, ischemic-type gastritis after initiating oral iron supplementation. Front Med (Lausanne) 2022 Nov 3;9:1010897. Laine LA et al. (starts at 9:17). Effect of oral iron therapy on the upper gastrointestinal tract. A prospective…
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Season 3, Episode 6 (Hydroxychloroquine and Oral Minoxidil for LPP, Gout in AKN, Shingles and EPDS, Renbok phenomenon, ACD in FFA/LPP)
1:05:03
1:05:03
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LEARNING OBJECTIVES By the end of the podcast, the listener should be able to Discuss the benefits of HCQ in LPP Outline allergens that may be relevant in LPP/FFA Discuss the benefits of LDOM in LPP Describe the Renbok phenomenon and how it relates to FFA Outline the potential triggers for EPDS Describe the relationship between AKN and gout EFFICAC…
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Season 3, Episode 5 (TE in Children, Post COVID Hair Loss, NAC for TTM and Trichobezoar)
1:15:52
1:15:52
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Season 3, Episode 5By Dr Jeff Donovan
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Season 3, Episode 4 (Oral Minoxidil for AGA, JAKI for AGA, PRP for AGA,COVID Vaccines and AA Risk, AA Rising Prevalence)
1:46:52
1:46:52
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Studies in Androgenetic Alopecia and Alopecia Areata STUDIES REFERENCED MINOXIDIL CONCENTRATIONS Singh et al (starts at 10:10). Does topical minoxidil at concentrations higher than 5% provide additional clinical benefit? Clin Exp Dermatol. 2022 Nov;47(11):1951-1955 Olsen EA, Dunlap FE, Funicella T et al (starts at 13:22). A randomized clinical tria…
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Season 3, Episode 3 (Resilience in AA, Hair Repigmentation and Melanoma, Accuracy of TikTok, Hair Straighteners & Uterine Cancer, Sebaceous Gland Atrophy in Seborrheic Dermatitis)
1:12:33
1:12:33
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Recording of the Evidence Based Hair Podcast for the Oct 24, 2022 issue. STUDIES REFERENCED Han JJ et al (starts at 5:28) Association of resilience and perceived stress in patients with alopecia areata: A cross-sectional study. J Am Acad Dermatol. 2022 Jul;87(1):151-153. Gressler J et al (starts at 20:55 ). Re-pigmentation of scalp hair - A feature…
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Season 3, Episode 2 (LPP, FFA, Checkpoint Inhibitor induced LPP, Scarring Alopecia ”Gene Signatures”, Alopecic and Aseptic Nodules of the Scalp)
1:18:44
1:18:44
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Recording of the Evidence Based Hair Podcast for the Oct 17, 2022 issue. LICHEN PLANOPILARIS COMORBIDITY STUDIES Conic et al (starts 8:19). Exploring the association between lichen planopilaris, cardiovascular and metabolic disorders. J Eur Acad Dermatol Venereol 2021 Nov;35(11):e826-e828. Joshi et al (starts 9:59). Comorbidities associated with li…
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Season 3, Episode 1 (Isotretinoin, Trichotillomania, Blue Sclera, Omicron, Tinea Capitis from Guinea Pigs)
1:10:22
1:10:22
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Recording of the Evidence Based Hair Podcast for the Oct 11, 2022 issue. TINEA CAPITIS STUDIES Cukierman E et al (starts at 5:18). Alopecia and pet: a case report. Einstein (Sao Paulo). 2022 Jul 4;20:eRC6881. TELOGEN EFFLUVIUM - COVID 19 Visconti A et al (starts at 20:00) Cutaneous Manifestations of SARS-CoV-2 infection during the Delta and Omicron…
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Season 2, Episode 10 (Oral minoxidil, Hair Fibers, HCQ in Pregnancy, Teriflunomide-induced Hair Loss, Do it Yourself Haircare, Premature Greying of Hair)
1:35:36
1:35:36
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1:35:36
ORAL MINOXIDIL IN PEDIATRICS Jerjen R et al (starts at 12:33). Low-dose oral minoxidil improves global hair density and length in children with loose anagen hair syndrome. Br J Dermatol. 2021;184(5):977-978. Nicolas-Ruanes et al (starts at 15:33). Low-dose oral minoxidil for treatment of androgenetic alopecia and telogen effluvium in a pediatric po…
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1
Season 2, Episode 9 (Isotretinoin and Finasteride for FFA, Eyelash Loss in FFA, Male FFA, LPP Incidence and Prevalence, CCCA Quality of Life)
1:03:33
1:03:33
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1:03:33
FRONTAL FIBROSING ALOPECIA : ISOTRETINOIN VS FINASTERIDE Rakowska A, et al (starts at 9:15). Efficacy of Isotretinoin and Acitretin in Treatment of Frontal Fibrosing Alopecia: Retrospective Analysis of 54 Cases. J Drugs Dermatol. 2017. Rokni GR et al (starts at 10:43). Evaluating the combined efficacy of oral isotretinoin and topical tacrolimus ver…
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1
Season 2, Episode 8 (COVID shedding, Trichotillomania, Traction Alopecia, Tinea Capitis Carrier State)
53:22
53:22
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53:22
STUDIES REFERENCED COVID RELATED SHEDDING Mazeto IFS et al (starts at 6:09). Ultrastructural evidence for anagen hair follicle infection with SARS-CoV-2 in early-onset COVID-19 effluvium. J Eur Acad Dermatol Venereol. 2022 Jun 20. Czech T et al (starts at 14:30). Characteristics of Hair Loss after COVID-19: Systematic Scoping Review. J Cosmet Derma…
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Season 2, Episode 7 (AGA and Smoking, Alopecia Areata and Eye Diseases, MTX for Pediatric AA, Upadacitinib for AA)
44:02
44:02
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44:02
Kavadya T and Mysore V (starts at 5:24). Role of Smoking in Androgenetic Alopecia: A Systematic Review. Int J Trichology. 2022 Mar-Apr; 14(2): 41–48. Mosley JG and Gibbs AC (starts at 6;30). Premature grey hair and hair loss among smokers: a new opportunity for heatlh education? British Medical Journal 1996; 313: 1616. Su LH and Chen T H-H (starts …
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Season 2, Episode 6 (JAK Inhibitors & Skin Cancer, Isotretinoin Labs, Triangular Alopecia, Hydroxychloroquine Retinopathy)
44:34
44:34
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44:34
JAK KINASE INHIBITORS AND SKIN CANCER Jalles et al (starts at 5:29). Skin cancers under Janus kinase inhibitors: A World Health Organization drug safety database analysis. Therapie. 2022 May 7;S0040-5957(22)00092-0. ISOTRETINOIN LAB MONITORING Xia E et al (starts at 13:36). Isotretinoin Laboratory Monitoring in Acne Treatment: A Delphi Consensus St…
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