Welcome to series II where we interview an early career researcher in every episode. In this series we showcase and celebrate the interdisciplinary nature of scientific research, with guests from a range of research fields, geographical locations, and faculty positions. Our episodes cover research areas spanning from studying bacteria and viruses, to computational chemistry for successful drug design. Analysing gunshot residue in forensic science, understanding aerosols and their importance ...
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Molecules, microbes and multiomics is DNA Genotek's podcast, featuring experts in all areas of the genomics, microbiome and multiomics space. To learn more about any of these emerging areas of science, tune in.
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Breaking new ground in PTSD research: Insights from The Consortium for Post-Traumatic Stress Disorders
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In this episode, Ajin Abraham (Strategic Marketing Manager, Genomics) and Sanna Abbasi, Ph.D. (Scientific Writer/Content Specialist) interview a group of leaders in the Psychiatric Genomics Consortium for Post-Traumatic Stress Disorders (PGC-PTSD). The purpose of the Psychiatric Genomics Consortium is to unite investigators around the world to cond…
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Expand into multi-omics: DNA Genotek and Diversigen 2021 grant program winner
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17:17
In this podcast, we interview Dr. Jonas Schluter, Assistant Professor from the Department of Microbiology at the Grossman School of Medicine at NYU Langone Health and a winner of the DNA Genotek and Diversigen 2021 Expand into Multi-omics grant, discuss his research.
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Phosphorus: Stretching the Capabilities of Clinical-Grade Genetic Testing
19:59
19:59
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We invited Alexander Bisignano, CEO of Phosphorus, to tell us more about his company’s application of genetic testing and to share what is in store for them in the future. By DNA Genotek
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Can the oral microbiome help law enforcement link suspects to crime scenes or evidence? In this episode of Molecules, Microbes and Multiomics Heloise Breton PhD, a product manager at DNA Genotek with a background in forensic science, and Megan Anderson, a recent graduate from Rock Canyon High School, chatted with us about Megan’s project on the ora…
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Urine the 'golden sample': Why is urine so exciting in cervical cancer prevention?
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We recently had the opportunity to interview Dr. Severien Van Keer, a post-doc researcher at the VAXINFECTIO research group, at the University of Antwerp. Her research primarily focuses on Human Papillomavirus (HPV) detection in first-void urine, and the potential of urine as a sample type for cervical cancer screening. Her research also includes N…
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Oral microbiome: The key to better therapeutics
24:16
24:16
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24:16
One new start-up microbiology company, Brick Built, is focused on the potential of the human oral microbiome. Our two microbiome product managers at DNA Genotek, Dr. Heloise Breton, and Laura Cunningham, had the pleasure of speaking with Brick Built Therapeutics co-founder Dr. Brian Klein about the role and future potentials of the oral microbiome …
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Leaving no microbe behind: Shoreline Biome’s easy solutions for microbiome NGS
11:57
11:57
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Shoreline Biome is a microbiome-focused company that provides simple solutions for microbiome next-generation sequencing. They develop tools and reagents to support end-to-end microbiome analysis. We talk about the amazing work of the team at Shoreline Biome and had the pleasure to interview their Director of R&D, Dawn Gratalo.…
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Behind the data: an interview with Dr. Dan Knights
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In this interview with Dr. Dan Knights, Senior Scientific Advisor of Diversigen, learn about the future of data generation from microbiome samples. Dr. Knights discusses how he started in microbiome and bioinformatics research, ways to increase the power of microbiome studies, and different signals within the microbiome.…
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RNA breakthroughs in autism, concussions, and COVID-19
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21:06
In this podcast, we explore how DNA Genotek and Quadrant Biosciences have been working together to support advancements in various diseases via RNA research and collection. Together, they've created RNA tests for early detection of autism spectrum disorder, Parkinson’s disease, traumatic brain injury, and COVID-19.…
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Probiotics, a possible solution to COVID-19 transmission?
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We interview a team from Duke University in Durham, North Carolina, who are exploring the impact of probiotics in COVID-19 transmission with a new clinical trial: Probiotics To Eliminate COVID-19 Transmission in Exposed Household Contacts (PROTECT-EHC).By Katherine Lawless
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Personalized skin care: the beauty industry diving into the microbiome
28:43
28:43
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28:43
The interest in human microbiome has widened from the gut to other parts of the human body, like skin. One company saw an opportunity to combine the science of the human skin microbiome, makeup and skincare. In this episode of Molecules, Microbes, and Multiomics, we interview the co-founders of Pure Culture Beauty Joy Chen, former CEO of Yes To and…
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Challenges and solutions for global shortages of materials for COVID-19 testing
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11:25
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When the pandemic hit, the demand for COVID-19 testing drastically increased, resulting in shortages of COVID-19 sampling and laboratory supplies and impacting the number of tests that could be performed. When we confirmed that our collection devices could stabilize, and inactivate the SARS-CoV-2 virus, we knew we could help. In this podcast we dis…
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Urine as a game-changing liquid biopsy in cancer biomarker detection
16:39
16:39
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We recently had the opportunity to interview Professor Patrick Pauwels, head of the laboratory of molecular pathology and co-director of CORE, a joint oncology research platform with the University of Antwerp. This podcast discusses the potential of liquid biopsies, such as urine in the field of cancer research especially when tissue is an issue. I…
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Dr Bryan Bzdek - Aerosols in Climate and Disease Transmission
18:27
18:27
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Dr Bryan Bzdek is a NERC independent research fellow in Aerosol Science based at the University of Bristol. In this episode Bryan introduces us to aerosols, what they are? And why they are important both for the climate, drug delivery and understanding disease transmission. To find out more about Bryan’s research and recent publications check out h…
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The question of “What is Metabolomics” has been buzzing around the scientific community. With the advances of new technology, a gateway to studying metabolomics has been opened. Over recent years, microbiome researchers have begun to incorporate metabolomics, the “missing piece of the puzzle”, as part of their multiomics studies To understand that …
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Dr Hannah Bruce Macdonald - Computational Chemistry for Drug Design
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Dr Hannah Bruce Macdonald is a Research Fellow in the Chodera Lab at Memorial Sloan Kettering Cancer Center. Hannah researches free energy methods for applications in drug design. In this episode we discuss, how are free energy calculations used in drug discovery? And how important are computational methods for modern drug synthesis? Twitter - http…
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Dr Daniel Angerhausen - Astrophysicist & Entrepreneur
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Today Dr Aleks & Dr Ines are joined by special guest Dr Daniel Angerhausen, who is an Astrophysicist and Astrobiologist Postdoctoral Researcher at ETH Zürich, co-founder and CEO of the start-up Explainables and mentor at the NASA Frontier Development lab. In this podcast episode, Daniel discusses his research, managing his different roles and the E…
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Solving the mysteries of your pet’s gut health
29:24
29:24
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Nom Nom is not your average pet food company. In addition to delivering fresh, healthy meals for cats and dogs created by a team of veterinary nutritionists, they use gut microbiome samples submitted by their customers to study the link between nutrition and pet health. Nom Nom partners with Diversigen to analyze these samples and provide the accur…
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Dr Matteo Gallidabino – Extracting Information from Chemical Evidence
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Dr Aleks Marsh and Dr Alan Mullan welcome back special guest Dr Matteo Gallidabino who is a Senior Lecturer in Forensic Science at Northumbria University. Matteo recently participated in series 1 of our podcast and has kindly agreed to join us for another episode. We ask Matteo what information can we extract from chemical evidence? How can chemica…
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Dr Giuseppe Aprea - Bacteriophages: The Good Guys of the Virus World
16:45
16:45
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In this episode Dr Aleks Marsh and Dr Alan Mullan welcome special guest, Dr Guiseppe Aprea who is an Official Veterinary Officer at the Experimental Zooprophylactic Institute of Abruzzo and Molise, Teramo in Italy. We discuss Bacteriophages and ask Giuseppe – what are bacteriophages? And why are these “good guys of the virus world” important for ap…
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Dr Heloise Stevance - Massive Stars and the Origins of Kilonovae and Supernovae
20:44
20:44
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In this episode Dr Aleks Marsh and Dr Ines Juvan-Beaulieu are joined by astrophysicist Dr Heloise Stevance. Heloise currently works as a research fellow at the University of Auckland, studying massive stars and the origins of Kilonovae and Supernovae. Heloise is also a Science Communicator and makes great astronomy graphics that are freely availabl…
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Detection and full genotyping of Human Papillomavirus (HPV) in first-void urine
24:43
24:43
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We recently had the opportunity to interview Rebecca Millecamps, a Marketing Manager at Fujirebio, a global leader in the field of in vitro diagnostics (IVD). In 2019, Novosanis and Fujirebio, signed a worldwide, non-exclusive agreement for the distribution of Colli-Pee®, Novosanis’ urine collection device for use with Fujirebio’s INNO-LiPA HPV gen…
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How to ensure the best sequencing results from saliva and fecal samples
23:01
23:01
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23:01
DNA Genotek has expertise with many different non-invasive sample types including saliva for genomic and feces for microbiome analysis. With any sample type, quality is paramount to generate the best sequencing results and subsequently to produce the most accurate data. In this podcast, Mike Tayeb and Brice LeFrancois, two experts from our research…
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SPARK project provides evidence for autism risk genes
13:50
13:50
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13:50
This episode of Molecules, microbes and multiomics features an interview with Pamela Feliciano, Ph.D. who is the Scientific Director for SPARK (Simons Foundation Powering Autism Research through Knowledge) Launched in 2016, SPARK is designed to speed up research and advance our understanding of autism. SPARK, the largest study of autism ever, aims …
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Industry leaders come together to support microbiome discovery
28:12
28:12
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28:12
As the microbiome industry grows and evolves, so has our team of microbiome experts. In 2019, DNA Genotek’s parent company, OraSure, acquired both CoreBiome and Diversigen. Through these acquisitions, we gained Diversigen's industry recognized CLIA/CAP state-of-the-art techniques with expert consultative microbiome services, and the strength of Cor…
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Life as a Tech Optimist – What does the future hold?
19:52
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Aleks, Alan and Conor discuss what it means to be a tech optimist; are we optimist about how technology can improve our lives? And, if so, what innovations are we excited about? What role can technology play in healthcare, environment and space exploration? Listen now to find out more.
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Today we welcome a special guest Professor Winfried Hensinger, the head of the Quantum Technologies research group at the University of Sussex. In this episode Aleks and Marcin ask Winfred what is quantum computing and how is this different to traditional computing? What different types of quantum computing technologies are available? And what prob…
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This episode features Dr Marcin, Dr Aleks and Dr Alan discussing the question how old is that apple? Seasonal fruit and vegetable products are available year-round thanks to improved food preservation techniques which are prevalent in our supermarkets. This poses the question are preserved foods nutritionally as valuable? And what impact do preserv…
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This episode features Dr Aleks Marsh and Dr Alan Mullan interviewing guest Dr Michael Mullan - yes, we have Alan’s dad on the show! Michael is a food scientist with experience in industry, research and teaching in several areas of food manufacturing. Michael was a Lecturer in Food Technology at Queen's University Belfast for 19 years and is current…
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In this episode Dr Marcin Barszczewski, Dr Aleks Marsh and Dr Alan Mullan debunk common science claims which are actually fiction. Have you heard the common sayings that you only use 10% of your brain? Goldfish have a 3 second memory and that humans only have five senses? All these claims are untrue but that leaves the following questions how much …
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From the air we breathe, to the water we drink, to the food we eat, microplastics are everywhere. In this episode Dr Marcin Barszczewski, Dr Aleks Marsh and Dr Alan Mullan discuss what are microplastics and where are they from? How do plastics and microplastics impact marine environments and get in the food chain? And how does this impact us and th…
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How is Machine Learning Helping Forensic Scientists?
20:31
20:31
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This week Dr Alan and Dr Aleks interview a special guest, Dr Matteo Gallidabino, a Senior Lecturer in Forensic Science at Northumbria University. Several of Matteo’s recent papers have discussed the use of machine learning in forensic science. In this episode we ask Matteo, what is machine learning? How is it implemented in forensic science? Should…
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Multiomics methods investigating aging process in man's best friend
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DNA Genotek speaks with researchers involved in the recently launched Dog Aging Project. The goal of the Dog Aging Project is to understand how genes, lifestyle, and environment influence aging and to use that information to help pets and people increase healthspan, the period of life spent free from disease. In this podcast, we speak with Dr. Dani…
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In this episode Aleks and Alan interview Conor about vertical farming. Conor has built his own prototype vertical farm to grow wheatgrass and recently visited Growing Underground an underground vertical farm in London! We ask Conor what is vertical farming? How much would crops produced from a vertical farm cost? And how much produce can we get wit…
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Are People Born Earlier in the School Year More Sucessful?
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This episode features Dr Marcin Barszczewski, Dr Aleks Marsh and Dr Alan Mullan discussing how school starting age impacts on future success. In this episode we discuss what is success? And how can we measure it? In the age of big data are we asking the right questions, collecting the right data and reaching the right conclusions? Is school merely …
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This episode features Dr Marcin Barszczewski, Dr Aleks Marsh and Dr Ines Juvan-Beaulieu discussing big questions like: Are we not alone? What trees would look like on other planets? And how could life evolve?
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Wood Wide Web: Do trees, plants and fungi have a social network?
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14:39
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This episode features Dr Marcin Barszczewski, Dr Aleks Marsh and Dr Alan Mullan discussing potentially scientifically contentious aspects of plant communication. We discuss what defines communication between plants? How can chemical signals be released from plants and detected by insects? Moreover, how can chemical signals be used to deter insect p…
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In this episode Aleks, Alan and Conor discuss what is organic farming? We consider whether organic farming methods which aim to reduce the use of synthetic pesticides, herbicides and the use of antibiotics provide a more sustainable method of food production. We discuss is organic food standardized by a central body? Is organic farming separate fro…
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The role of the microbiome in childhood determinants of cardiovascular health
22:05
22:05
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The Cardiovascular Risk in Young Finns Study is a prospective longitudinal study initiated in 1980. It is one of the largest follow-up studies into cardiovascular risk from childhood to adulthood. The main aim is to determine the contribution made by childhood lifestyle, biological, and psychological measures to the risk of cardiovascular diseases …
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This episode features Dr Marcin Barszczewski, Dr Aleks Marsh and Dr Alan Mullan discussing how modern-day DNA can determine your ancestral heritage? What is the difference between being related to and being descended from someone? What are the different types of DNA tests, what are they used for and what information can we get from them?…
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PREdiCCT: the largest study on predicting IBD disease flare
27:21
27:21
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This week, I interview Dr. Charlie Lees and Lee Murphy, investigators for the PREdiCCt Study (Prognostic effect of environmental factors in Crohn’s and Colitis). PREdiCCt is a major study at the University of Edinburgh that is actively recruiting now. This is the first study of its kind and it is directed towards understanding how environmental fac…
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The challenges and opportunities of collecting RNA for human microbiome studies
16:10
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Jean Macklaim is a Bioinformatician at DNA Genotek who has an extensive history with RNA research. Jean received her PhD in Biochemistry and Bachelor of Science in Human Genetics from the University of Western Ontario where she focused on sequencing technologies and bioinformatics methods to understand the structure and function of the microbiome i…
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An interview with Stephen Tang, President and CEO of OraSure Technologies and its subsidiaries DNA Genotek, CoreBiome and Novosanis. Steve spoke about how he fosters a culture of innovation across the entire organization. In the podcast, he discusses how innovation helps the organization respond to change, how developing people and creating opportu…
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Saliva as a sample type for genomic applications
14:05
14:05
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This week, I interview Scott Rabuka, Director of the Genomics Program at DNA Genotek for our podcast, Molecules, Microbes and Multiomics. Scott joined DNA Genotek in 2008 as the product manager for Oragene and successfully expanded the product into a complete family of solutions for global genomic research and clinical use. He is responsible for th…
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Some exciting news… we’d like to invite you all to listen to the pilot recording of the first ever Andor podcast, entitled “The Good, the Bad and the Interesting”. The Podcast will feature some of our biggest Andor personalities discussing topics that are of interest to them. Special guests will also be joining to bring an expert insight into a par…
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Urine as a liquid biopsy for cancer detection
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10:21
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10:21
We recently had the opportunity to visit our new sister company, Novosanis, in Antwerp, Belgium, to talk about urine as a sample type. Novosanis is dedicated to solving urine sampling challenges through its product Colli-Pee™ - an award-winning device designed to efficiently and hygienically capture first-void urine (the first 20ml of a urine sampl…
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We recently introduced listeners of Molecules, microbes and multiomics to our sister company, CoreBiome, a privately-held, Minnesota-based microbiome analysis company that accelerates discovery for customers in the pharmaceutical, agricultural, environmental and research communities. We are continuing this story via an interview with CoreBiome co-f…
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The microbiome challenges CoreBiome was built to solve
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8:35
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In the podcast, Dr. Dan Knights, co-founder and CEO of CoreBiome discusses the problems CoreBiome was built to solve and the challenges surrounding reproducibility in the microbiome field. You’ll learn why he “geeks out” about quality, efficiency, and accuracy and how his team keeps CoreBiome at the forefront of the microbiome industry. Learn more …
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