Dr. Arthur sit describes his surprising research results on the effect of scleral buckle on ocular fluid dynamics. The discussed article: Lyons LJ, Kazemi A, Bakri SJ, Barkmeier AJ, Iezzi R, Olsen TW, Hodge DO, Sit AJ. The Effect of Scleral Buckle Surgery on Tonographic Outflow Facility, Positional Intraocular Pressure, and Ocular Biomechanics. Oph…

Dr. Paul Micevych from the UC San Francisco discusses his group's work on systemic and individual risk factors leading to complicated diabetic retinopathy requiring vitrectomy. Discussed article: Micevych PS, Taha AM, Poddar A, Stewart JM. Individual and Systems-Based Risk Factors for Diabetic Vitrectomy in an Urban Safety-Net Hospital. Ophthalmol …

Dr. Nina Ahuja and Dr. Nupura Bakshi elaborate on the concept of Equity, Diversity and Inclusion in medicine and discuss their recent publication about the EDI landscape in the Canadian ophthalmology post-secondary programs. The discussed article: Lee EY, Farrokhyar F, Bakshi N, Levin LA, Ahuja N. Equity, diversity, and inclusion landscape in Canad…

Dr. Sarraf talks about his group's work on the correlation of PED size and variablity and the visual improvement during the treatment of neovascular AMD as analyzed using data from HAWK and HARRIER studies. Referenced article: Sarraf D, Khanani AM, Sadda SR, Chang A, Wong DT, Kempf AS, Saffar I, Tang S, Tadayoni R. PIGMENT EPITHELIAL DETACHMENT THI…

Dr. Jong Park discusses surgical mananement of full-thickness macular holes associated with macular telangiectasia. Referenced article: Park JG, Adrean SD, Begaj T, Capone A Jr, Charles S, Chen SN, Chou HD, Cohen MN, Corona ST, Faia LJ, Garg SJ, Garretson BR, Gregori NZ, Haller JA, Houghton OM, Hsu J, Jo J, Kaiser RS, Lai CC, Mahgoub MM, Mansoor M,…

Dr. Landon Rohowetz discusses his group's findings of a retrospective analysis of the characteristics of Retinal Detachment cases that were associated with Retinal Dialysis. Discussed article: Rohowetz LJ, Jabbehdari S, Smiddy WE, Berrocal AM, Townsend JH, Chang JS, Yannuzzi N, Sridhar J, Haddock LJ, Fortun JA, Flynn HW Jr; Retinal Dialysis Study G…

Dr. Jabs and Dr. Acharya discuss the results of the MERIT trial that investigated relative efficacy of intrvitreal injections of Dexamethasone implant vs ranibizumab vs methotrexate for the treatment of macular oedema associated with uveitis. Discussed article: Multicenter Uveitis Steroid Treatment Trial (MUST) Research Group, Writing Committee:; A…

Prof. Gemmy Cheung from the National University of Singapore and Singapore National Eye Center discusses her research results on progression of Geographic Atrophy on Asian vs non-Asian Eyes. References Article: Teo KYC, Fujimoto S, Sadda SR, Kokame G, Gomi F, Kim JE, Cheng MFS, Corradetti G, Amornpetchsathaporn A, Chainakul M, Lee WK, Lai TYY, Ruam…

Dr. Regillo describes the results of the phase 3 prospective study of Ranibizumab Port Delivery System (PDS) for the treatment of neovascular AMD. Reference Article: Regillo C, Berger B, Brooks L, Clark WL, Mittra R, Wykoff CC, Callaway NF, DeGraaf S, Ding HT, Fung AE, Gune S, Le Pogam S, Smith R, Willis JR, Barteselli G. Archway Phase 3 Trial of t…

Dr. Smiddy presents a cost analysis of the step therapy for treatment of diabetic macular edema based on DRCR protocol AC results. Discussed article: Patel NA, Al-Khersan H, Yannuzzi NA, Lin J, Smiddy WE. Aflibercept Monotherapy versus Bevacizumab-First for Diabetic Macular Edema: A Cost Analysis Based on Diabetic Retinopathy Clinical Research Netw…

Dr. Jason Hsu from Wills Eye Hospital returns to The Retina Channel to discuss his groups' retrospective study of eyes with advanced retinal detachement (PVR grade C or worse) that underwent retinectomy without lensectomy. Their study showed that 75% of these eyes at 3 months (and 68% at 6 months) had single surgery anatomic success. The study is s…

Dr. Jay Duker speaks about the results of the DAVIO trial which was a phase 1 trial investigating an intravitreal implant (EYP-1901) containg vorolanib (a VEGF and receptor blocker) in a bioerodible Durasert implant for the treatment of wet AMD.

Dr. Noemi Lois from Queens University in Belfast, UK discusses results of the DIAMONDS study, which was a prospective trial that looked into the effectiveness, safety, and cost-effectiveness of subthreshold micropulse laser (SML), compared with standard laser (SL), for diabetic macular edema (DME) with central retinal thickness (CRT) < 400 um. Refe…

Dr. Xuejing Chen discusses her group's retrospective analysis of the incidence and risk factors of delayed retinal breaks following a symptomatic posterior vitreous detachment. Discussed article: Jindachomthong KK, Cabral H, Subramanian ML, Ness S, Siegel NH, Chhablani J, Hsu SX, Chen X. Incidence and risk factors for delayed retinal tears followin…

Dr. Jhavery discusses results of DRCR Retina Protocol AC study which compared DME response to anti-VEGF injections in patients who received Aflibercept monotherapy vs those who started with Bevacizumab first and then switched to Aflibercept if needed. Discussed article: Jhaveri CD, Glassman AR, Ferris FL 3rd, Liu D, Maguire MG, Allen JB, Baker CW, …

Dr. J. Fernando Arevalo discusses results of an international multicenter study that compared surgical success rates of vitrectomy vs vitrectomy + scleral buckle to repair retinal detachments due to giant retinal tears. The study collected 200 patients data over a 12 year period. Referenced article: Ong SS, Ahmed I, Gonzales A, Al-Fakhri AS, Al-Sub…

Dr. Finn discusses her groups' case series on temporal associattion CRVO and HRVO in young healthy patients after COVID-19 infection. Discussed article: Ashkenazy N, Patel NA, Sridhar J, Yannuzzi NA, Belin PJ, Kaplan R, Kothari N, Benitez Bajandas GA, Kohly RP, Roizenblatt R, Pinhas A, Mundae R, Rosen RB, Ryan EH Jr, Chiang A, Chang LK, Khurana RN,…

Dr. Birger Lindtjørn from Norway discusses his team's prospective trial on comparison of SF6 vs air tamponade in vitrectomy for closure of small-medium macular holes. Discussed article: Lindtjørn B, Krohn J, Haugstad M, Stene-Johansen I, Austeng D, Basit S, Fossen K, Varhaug P, Kvaløy JT, Forsaa VA. Air versus Sulfur Hexafluoride Gas Tamponade for …

Prof. Guymer from Melbourne Univeristy discusses finding of a prospective study on absence of association between retinal pseudodrusen and advanced AMD. Discussed article: Wu Z, Kumar H, Hodgson LAB, Guymer RH. Reticular Pseudodrusen on the Risk of Progression in Intermediate Age-Related Macular Degeneration. Am J Ophthalmol. 2022 Mar 11:S0002-9394…

Dr. Ballios discusses his group's findings on novel mutations in the RCBTB1 gene that can cuase late-onset non-syndromic retinal dystrophies mimicking macular degeneration. Full article: Catomeris AJ, Ballios BG, Sangermano R, Wagner NE, Comander JI, Pierce EA, Place EM, Bujakowska KM, Huckfeldt RM. Novel RCBTB1 variants causing later-onset non-syn…

Dr. Kumar discussed his group's prospective study on the comparative outcomes of two different drainage techniques (posterior retinotomy vs PFCL) for repair of rhegmatogenous retina detachment.

Dr. David Sarraf from UCLA discusses Paracentral Acute Middle Maculopathy (PAMM) and its the ischemic implications. Discussed article: Wang D, Au A, Duker JS, Sarraf D. PAMM and the ischemic cascade associated with radiation retinopathy. Am J Ophthalmol Case Rep. 2020 Sep 8;20:100918. doi: 10.1016/j.ajoc.2020.100918. PMID: 32984654; PMCID: PMC74950…

Dr. Kourous Rezaei reviews the results of the GATHER1 trial on complement C5 inhibition for slowing down progression of geography atrophy in dry AMD. References article: Jaffe GJ, Westby K, Csaky KG, Monés J, Pearlman JA, Patel SS, Joondeph BC, Randolph J, Masonson H, Rezaei KA. C5 Inhibitor Avacincaptad Pegol for Geographic Atrophy Due to Age-Rela…

Dr. Kokame from the University of Hawaii reports a novel method of repairing certain types of retinal detachment using minimized eye movement followed by laser retinopexy. Referenced article: Kokame GT, Yee S, Omizo JN, Villanueva L, Liu J. Laser Treatment after Minimized Eye Movement for Repair of Retinal Detachment. Ophthalmol Retina. 2021 Sep;5(…

Dr. Efrem Mandelcorn from the University of Toronto talks about 3 different surgical techniques that he's published in 3 different articles: 1. Macular hydodissection for challenging macular holes: Felfeli T, Mandelcorn ED. MACULAR HOLE HYDRODISSECTION: Surgical Technique for the Treatment of Persistent, Chronic, and Large Macular Holes. Retina. 20…

Professors Sahel and Roska describe partial visual recovery of a patient with advanced RP using optogenetic technology. Discussed article: Sahel JA, Boulanger-Scemama E, Pagot C, Arleo A, Galluppi F, Martel JN, Esposti SD, Delaux A, de Saint Aubert JB, de Montleau C, Gutman E, Audo I, Duebel J, Picaud S, Dalkara D, Blouin L, Taiel M, Roska B. Parti…

Dr. Seider elaborates on his group's large retrospective study on rates and risk factors for complicated acute posterior vitreous detachment. Full reference to the discussed article: Seider MI, Conell C, Melles RB. Complications of Acute Posterior Vitreous Detachment. Ophthalmology. 2021 Jul 27:S0161-6420(21)00552-2. doi: 10.1016/j.ophtha.2021.07.0…

Dr. Tina Felfeli discusses 3 articles around COVID-19 and ophthalmology: (1) Effect of various concretions and exposure times of common ophthalmology anti-septics on COVID-19 infected cell lines. (2) Effect of the pandemic on the backlog of elective ophthalmic surgical cases in the province of Ontario, Canada (3) Detection of the COVID-19 virus in …

Dr. Almeida presents a mathematical model based on Newtonian mechanics to discuss vision recovery of different anti-VEGF medications. The discussed article: Almeida DRP, Ruzicki J, Xu K, Chin EK. Vision Recovery Velocity, Momentum and Acceleration: Advanced Vitreoretinal Analytics as Measure of Treatment Efficacy for Neovascular Age-Related Macular…

Dr. Sabri discusses his group's analysis of various screening criteria to detect visually significant Retinopathy of Prematurity while minimizing unnecessary retinal exams. Discussed article: Sabri K, Shivananda S, Farrokhyar F, Selvitella A, Easterbrook B Kin B, Seidlitz W, Lee SK; Canadian Neonatal Network and the Canadian Association of Pediatri…

Dr. Raj Maturi from the DRCR Retina Network discusses effect of early anti-VEGF injections in moderate-severe NPDR to prevent vision-threatening complications of diabetic retinopathy. This is the 2-year results of a 4-year study. Discussed article: Maturi RK, Glassman AR, Josic K, Antoszyk AN, Blodi BA, Jampol LM, Marcus DM, Martin DF, Melia M, Sal…

Dr. Daniel Lavinsky describes the results of a small randomized controlled clinical trial investigating functional and anatomical outcomes of using nondamaging retinal laser for the treatment of macular telangiectasia type II. The discussed article: Lavinsky D, Silva MOD, Chaves AE, Schneider WFM, Lavinsky F, Palanker D. FUNCTIONAL AND STRUCTURAL E…

Dr. Antoszyk from the DRCR Retina Network discusses Protocol AB, which compared anti-VEGF injections vs immediate pars plana vitrectomy for the treatment of vitreous hemorrhage due to proliferative diabetic retinopathy. The discussed article: Antoszyk AN, Glassman AR, Beaulieu WT, Jampol LM, Jhaveri CD, Punjabi OS, Salehi-Had H, Wells JA 3rd, Magui…

Dr. Nina Ahuja (@docsleadership) discusses her newly published booked titled "Stress in Medicine, Lessons Learned Through my Years as a Surgeon, from Med School to Residency, and Beyond". In an intimate account of her journey through her medical career, Dr. Ahuja discusses some of hardships and difficulties that she has gone through with the goal o…

Dr. Sridhar (host of the Straight from the Cutter's Mouth podcast) discusses his recent article on the trends of women's representation in VR meetings in the US between 2015 and 2019. The discusses article: Sridhar J, Kuriyan AE, Yonekawa Y, Berrocal A, Khan MA, Chan RVP, Haller JA. Representation of Women in Vitreoretinal Meeting Faculty Roles fro…

Dr. Pereira speaks about his group’s report on retinal findings in patients with severe COVID-19 infections who were admitted in the ICU. Discussed article: Pereira LA, Soares LCM, Nascimento PA, et al. Br J Ophthalmol Epub ahead of print: [please include Day Month Year]. doi:10.1136/bjophthalmol- 2020-317576…

Dr. Zicarelli discusses his group's 10-yr retrospective analysis on the prognostic factors associated with Peripheral exudative hemorrhagic chorioretinpathy. Discussed article: Zicarelli F, Preziosa C, Staurenghi G, Pellegrini M. Peripheral exudative haemorrhagic chorioretinopathy: a widefield imaging study. Br J Ophthalmol. 2020 Sep 3:bjophthalmol…

Dr. Niffenegger discusses a case series of secondary macular hole treatment with topical therapy. Discussed article: Niffenegger JH, Fong DS, Wong KL, Modjtahedi BS. Treatment of Secondary Full-Thickness Macular Holes with Topical Therapy. Ophthalmol Retina. 2020 Jul;4(7):695-699. doi: 10.1016/j.oret.2020.01.014. Epub 2020 Jan 28. PMID: 32284268.…

Dr. Baumal discusses features and outcomes of eyes with retinal vasculitis and intraocular inflammation after intravitreal injection of brolucizumab for treatment of neovascular age-related macular degeneration. Discussed article: Baumal CR, Spaide RF, Vajzovic L, et al. Retinal Vasculitis and Intraocular Inflammation after Intravitreal Injection o…

Dr. Koh from Singapore National University Hospital discusses his team's simulation study on aerosol transmission through slit lamp shields and face masks. Discussed article: Chuan OS, Bin Razali MA, Shaffiee L, Xing YJ, Yin Fei TT, Chee LS, Koh V, Do slit lamp shields and face masks protect ophthalmologists amidst COVID-19?, Ophthalmology (2020), …

Drs. Lee and Apte discuss their recent paper on our current understanding of using retinal imaging biomarkers to evaluate Alzheimer's disease. Discussed article: Lee CS, Apte RS, Retinal Biomarkers of Alzheimer’s Disease, American Journal of Ophthalmology (2020), doi: https://doi.org/10.1016/j.ajo.2020.04.040.…

Dr. Gupta discusses findings of this large retrospective study on the risk and associations of rhegmatogenous retinal detachment after intravitreal anti-VEGF injections. Discussed article: Storey PP, Pancholy M, Wibbelsman TD, et al. Rhegmatogenous Retinal Detachment after Intravitreal Injection of Anti-Vascular Endothelial Growth Factor. Ophthalmo…

In a panel discussion with Dr. Koushan, Drs. Daniel Ting, Olivia Li and Steven Yeh discuss the preparedness of ophthalmologists in the COVID-19 crisis. The discussion is based on the most recent Ophthalmology editorial: Preparedness among Ophthalmologists: During and Beyond the COVID-19 Pandemic. Olivia Li, Ji-PengWong, Tien Y.Wong, Edmund Y.Mehta,…

Dr. Leffler discusses his team's analysis of the country-wide mortality from COVID-19 pandemic and its correlation with mask usage by the public. Full reference: Leffler CT, Ing E, McKeown CA, Pratt D, Grzybowski A. Final Country-wide Mortality from the Novel Coronavirus (COVID-19) Pandemic and Notes Regarding Mask Usage by the Public. April 4, 202…

Dr. Shildkrot discusses progression of glaucomatous changes in 28 eyes that were receiving anti-VEGF injections. Discussed article: Effects of Intravitreal Anti-VEGF Therapy on Glaucoma-like Progression in Susceptible Eyes, Du, Jeanette MD; Patrie, James T ; Prum, Bruce E.; Netland, Peter A.; Shildkrot, Yevgeniy (Eugene) MD, Journal of Glaucoma: De…

Dr. Philip Hykin discusses the LEAVO trial which was a large prospective trial comparing the efficacy of three main anti-VEGF intravitreal injections (bevacizumab, ranibizumab and aflibercept) for treating macular edema secondary to Central Retinal Vein Occlusion. The discussed article: Clinical Effectiveness of Intravitreal Therapy With Ranibizuma…

Dr. Vander from Wills Eye Hospital discusses the effect of vitreous tap on the management of 60 cases of endophthalmitis post intravitreal anti-VEGF injections. The discussed article: Changes in Management Based on Vitreous Culture in Endophthalmitis After Intravitreal Anti-vascular Endothelial Growth Factor Injection. Patel SN, Storey PP, Pancholy…

Dr. Guymer discusses the results of the FLUID study which investigated whether some residual sub retinal fluid can be tolerated in neovascular macular degeneration. Full reference: Tolerating Subretinal Fluid in Neovascular Age-Related Macular Degeneration Treated with Ranibizumab Using a Treat-and-Extend Regimen. Guymer, Robyn H.Chang, Andrew et a…

Dr. Soliman discusses his team's analysis of clinical predictors of low histopathology in eyes that were enucleated because of retinoblastoma. The goal of the study is to find clinical indicators in retinoblastoma that could be used to salvage eyes via eye-preserving treatment methods instead of enucleation.…

Drs. Muni and Juncal discuss their case series on the level of anti-VEGF drugs and VEGF-A levels on lactating mothers who had received intravitreal anti-VEGF injections. Reference for the article: Ranibizumab and Aflibercept Levels in Breast Milk after Intravitreal Injection; Verena R. Juncal,Quratulain Paracha,Motaz Bamakrid, ,Carolina L.M. Franci…