Lupus Science and Medicine is a global, peer reviewed, Open Access, online journal that provides a central point for publication of basic, clinical, translational, and epidemiological studies of all aspects of lupus and related diseases. It is the first lupus-specific Open Access journal in the world and was developed in response to the need for a barrier-free forum for publication of groundbreaking studies in lupus.
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The Women in Science and Medicine podcast features discussions with female scientists within West Virginia University and other institutions. In this series, we’ll share the achievements and insights from some of the country’s top female scientists and learn from their experiences to understand how they came to be passionate about science and overcame any obstacles in their paths. This podcast is offered by West Virginia University’s Office of Research and Graduate Education.
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In a world brimming with groundbreaking discoveries and technological advancements in medicine and science, equitable access to life-saving cures and treatments remains a pressing concern. Join us on a riveting journey through my podcast series, where we delve into the heart of pioneering research, innovative breakthroughs, and the tireless efforts of scientists and doctors to make healthcare accessible and affordable for all. Through thought-provoking conversations with leading experts, pas ...
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Some of the world's greatest scientists, doctors and medical researchers share their discoveries and visions onstage at the TED conference, TEDx events and partner events around the world. You can also download these and many other videos free on TED.com, with an interactive English transcript and subtitles in up to 80 languages. TED is a nonprofit devoted to Ideas Worth Spreading.
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A podcast focused on profiling inspiring people in the fields of medicine and science. You can't be what you can't see. Co-hosted by Aoifinn Devitt and Maeve McQuillan.
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Dr. Craig Heller: Pioneering Equitable Advancements in Sleep, Temperature Regulation, and Down syndrome Research
20:10
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Join host Erika Ruiz for an informative discussion with Dr. Craig Heller on this episode of The Endless Pursuit - Equitable Science and Medicine podcast. Dr. Heller, a distinguished biologist at Stanford University, leads pioneering research in sleep and circadian rhythms, focusing on their impact on learning and memory in Down syndrome. His innova…
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Understanding the Critical Role of Lupus Clinical Trial Outcome Measures in Advancing Therapeutic Development
19:43
19:43
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Join Dr. Anna Wolska from the Lupus Foundation of America and Dr. Laurent Arnaud, Professor of Rheumatology at the Department of Rheumatology, University Hospitals of Strasbourg as they discuss systemic lupus erythematosus (SLE) clinical trials. In this episode, Dr. Arnaud highlights the complexities of drug approval processes in lupus, the pivotal…
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The WISM podcast returns with another in a series highlighting alumni of WVU! Mallory chats with Dr. Amanda Stover, now an Assistant Professor at Clemson University in their Department of Public Health Services. They discuss her Appalachia-relevant research at the intersection of mental health and suicide and substance abuse. They also talk about D…
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Interpreting Hydroxychloroquine Blood Levels in Lupus
20:29
20:29
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Join Dr. Anna Wolska from the Lupus Foundation of America as she delves into a groundbreaking discussion with Dr. Stephen Balevic focused on hydroxychloroquine blood levels and understanding medication adherence in lupus patients. In this episode, Dr. Balevic, a rheumatologist and clinical pharmacologist from Duke University, explains the nuances o…
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Use of Artificial Intelligence and Machine Learning in Clinical Practice
11:51
11:51
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Join Dr. Anna Wolska and Dr. May Choi as they explore the role of Artificial Intelligence (AI) and Machine Learning (ML) in guiding diagnostic and care decisions for systemic lupus erythematosus (SLE). Dr. Choi delves into key elements of machine learning and its potential impact on improving outcomes, particularly in underserved populations. She a…
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Dr. Brian Skotko: Advancing Down syndrome Research for Equitable Healthcare Access
11:15
11:15
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Join host Erika Ruiz for an engaging conversation with Dr. Brian Skotko on this episode of The Endless Pursuit - Equitable Science and Medicine podcast. Dr. Skotko is the Emma Campbell Endowed Chair on Down syndrome and serves as Director of the Down syndrome Program at Massachusetts General Hospital. With a personal connection to Down syndrome thr…
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Where does your sense of self come from? A scientific look | Anil Ananthaswamy
12:49
12:49
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Our memories and bodies give us clues about who we are, but what happens when this guidance shifts? In this mind-bending talk, science writer Anil Ananthaswamy shares how the experiences of "altered selves" -- resulting from schizophrenia, Alzheimer's, foreign limb syndrome or other conditions -- shed light on the constructed nature of identity. He…
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Dr. Mark Mattson: Intermittent Fasting Could Be the Key to Healthy Aging and Preventative Medicine
12:26
12:26
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Join host Erika Ruiz in a compelling conversation with Dr. Mark Mattson on this episode of The Endless Pursuit - Equitable Science and Medicine podcast. Dr. Mattson, an esteemed adjunct professor of neuroscience at Johns Hopkins University School of Medicine and former NIH lab chief with a PhD in neuroendocrinology, shares insights from his revolut…
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Dr. Dennis Selkoe: Pioneering Neurodegenerative Research & Advancements in Alzheimer's Treatment
15:13
15:13
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Join host Erika Ruiz in an enlightening discussion with Dr. Dennis Selkoe, a distinguished neurology professor at Harvard Medical School and a leading expert in Alzheimer's and Parkinson's diseases. Leading a team of 300+ scientists at the Ann Romney Center for Neurologic Diseases at Brigham and Women's Hospital, Dr. Selkoe's pioneering research ha…
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To RNase or Not to RNase: That Is the Question
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Join Dr. Anna Wolska and Dr. Jim Posada as they delve into the intricacies of RNAse therapy in the management of Systemic Lupus Erythematosus (SLE). In this podcast episode, Dr. Posada describes the groundbreaking study evaluating the efficacy of RSLV-132, a novel RNAse molecule fused to human IgG1 Fc, in reducing chronic inflammation associated wi…
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A decision-aid facilitates patient understanding of benefits vs. risk of hydroxychloriquine use as part of routine care for lupus
15:05
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Dr. Anna Wolska engages in a conversation with Dr. Shivani Garg and Dr. Christie Bartels to delve into the development and implementation of HCQ-SAFE. This innovative decision-aid is designed to empower individuals living with lupus to engage in shared-decision making. The authors discuss the importance of streamlining and enhancing shared decision…
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Episode 16: Maternal Mortality: A Modern Crisis: Part 3 - looking around the world to global solutions
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In the US, every 12 hours a woman dies due to complications resulting from pregnancy. Additionally, 2 babies die each day. According to data from the national center for health statistics the maternal mortality rate for 2021 was 32.9 deaths per 100,000 live births, compared with a rate of 23.8 in 2020 and 20.1 in 2019 In 2021, the maternal mortalit…
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Episode 15: Maternal Mortality: A Modern Crisis: Part 2: Exploring Solutions
21:10
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In the US, every 12 hours a woman dies due to complications resulting from pregnancy. Additionally, 2 babies die each day. According to data from the national center for health statistics the maternal mortality rate for 2021 was 32.9 deaths per 100,000 live births, compared with a rate of 23.8 in 2020 and 20.1 in 2019 In 2021, the maternal mortalit…
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Episode 14: Maternal Mortality - A Modern Crisis: Part 1 - Exploring the Problem
25:46
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In the US, every 12 hours a woman dies due to complications resulting from pregnancy. Additionally, 2 babies die each day. According to data from the national center for health statistics the maternal mortality rate for 2021 was 32.9 deaths per 100,000 live births, compared with a rate of 23.8 in 2020 and 20.1 in 2019 In 2021, the maternal mortalit…
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Dual dsDNA testing may be needed to fully understand patient disease status
21:40
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Dr. Anna Wolska speaks to Dr. Michael Belmont and Devyn Zaminski to discuss the importance of dual dsDNA testing in order to full understand disease activity. In this study, they made the observation that there is a large amount of discordance in anti-dsDNA antibodies assays. Misinterpretation or errors in anti- dsDNA antibody testing could have ne…
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The WISM podcast returns with one of WVU’s very own! Mallory chats with Dr. Savannah Sims, a graduate of the Biomedical Sciences Ph.D. program. She’s a passionate advocate of STEM and directed her career towards that aim. Dr. Sims relates inspiring and practical advice around finding your passion as a scientist, pushing against your comfort barrier…
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Is Anifrolumab an effective treatment for lupus nephritis?
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Dr. Anna Wolska engages in a discussion with renowned experts, Dr. Catharina Lindholm and Dr. David Jayne, to explore findings from the phase II TULIP Lupus Nephritis trial. This in-depth conversation centers on results from a clinical trial where they evaluated the efficacy of intensified anifrolumab treatment in individuals with active lupus neph…
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Which one is better at controlling lupus: Belimumab or Anifrolumab?
12:38
12:38
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Dr. Anna Wolska sits down with experts, Dr. Michelle Petri and Dr. Nick Ballew, analyzing the effectiveness of SLE treatments Belimumab and Anifrolumab. The conversation delves into their meticulous study, where they examined the 52-week SLE Responder Index (SRI)-4 responses, providing crucial data for informed lupus patient care. The study data, b…
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Managing Lupus Nephritis: Importance of Immunosuppression and Mitigation of Tissue Fibrosis
23:27
23:27
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Dr. Anna Wolska from the Lupus Foundation of America interviews Drs. Ana Malvar and Brad Rovin. They discuss using repeat tissue biopsies to understand progression of lupus nephritis over time. They offer conjecture that both immunosuppression as well as mitigation of tissue fibrosis, resulting from inflammatory resolution, are needed in order to p…
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Testing a new measure of lupus improvement that encompasses the patients’ perspectives and doctors’ evaluations
18:05
18:05
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Dr. Anna Wolska from the Lupus Foundation of America interviews Drs. Anca Askanase and Joan Merrill, the developers of the LFA-REAL tool. Together, they discuss the importance of using a tool like LFA-REAL to understand how clinician and patient reported outcomes are essential for understanding efficacy and effectiveness of experimental therapeutic…
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Understanding Lupus: Exploring the Differences between Type 1 and Type 2 Symptoms
20:25
20:25
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Dr. Anna Wolska from the Lupus Foundation of America interviews Dr. Amrie Grammer and Dr. Peter Lipsky from AMPEL BioSolutions. Together they describe the molecular endotypes of Type 1 and Type 2 Systemic Lupus Erythematosus. This episode uncovers the distinct molecular profiles of these SLE types and paves the way for personalized treatment approa…
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Unpacking Lupus Treatment: How Quickly Does Anifrolumab Start Working? Insights from TULIP Trials
14:42
14:42
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Dr. Anna Wolska from the Lupus Foundation of America interviews Dr. Ian Bruce, from the University of Manchester in the UK. Dr Bruce discusses the time to onset of clinical response to Anifrolumab in patients with Systemic Lupus Erythematosus. The episode delves into pooled data from two significant Phase III trials, TULIP-1 and TULIP-2, offering l…
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Mallory sits down with Dr. Carrie Shaffer, Assistant Professor in the Veterinary Science, Pharmaceutical Sciences, and Microbiology, Immunology and Molecular Genetics Departments at the University of Kentucky. They discuss her passionate pursuit of science from a very early age, some of the unique characteristics and duties of land grant institutio…
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Could we treat Alzheimer's with light and sound? | Li-Huei Tsai
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What if we could use brain waves to treat Alzheimer's? Professor and neuroscientist Li-Huei Tsai details a promising new approach to artificially stimulate gamma brain waves using light and sound therapy, to increase connectivity and synchrony and delay the onset of this deadly disease. This non-invasive therapy has already been shown to work in mi…
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Are life-saving medicines hiding in the world's coldest places? | Normand Voyer
12:17
12:17
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Could the next wonder drug be somewhere in Canada's snowy north? Take a trip to this beautiful, frigid landscape as chemist Normand Voyer explores the mysterious molecular treasures found in plants thriving in the cold. These scarcely investigated organisms could hold immense medical promise, he says – so long as we work quickly enough to discover …
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Are life-saving medicines hiding in the world's coldest places? | Normand Voyer
11:56
11:56
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Could the next wonder drug be somewhere in Canada's snowy north? Take a trip to this beautiful, frigid landscape as chemist Normand Voyer explores the mysterious molecular treasures found in plants thriving in the cold. These scarcely investigated organisms could hold immense medical promise, he says – so long as we work quickly enough to discover …
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Biomarker reduction indicates treatment response to Belimumab
14:35
14:35
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Dr. Anna Wolska from the Lupus Foundation of America interviews Dr. Andrea Fava from Johns Hopkins University about Belimumab treatment in lupus nephritis. Dr Fava elucidates on the correlation between the decrease in urinary CD163 levels and the response to Belimumab treatment in Lupus Nephritis trials. The conversation provides important insights…
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What to do when there's a polar bear in your backyard | Alysa McCall
10:46
10:46
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As Arctic ice melts, polar bears are being forced on land -- and they're hungry. With the apex predators frequently turning to human junkyards for a snack, northern towns have had to get creative in order to keep both their people and wildlife safe. Biologist and conservationist Alysa McCall shares lessons from the field on how to safely navigate c…
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What to do when there's a polar bear in your backyard | Alysa McCall
10:33
10:33
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As Arctic ice melts, polar bears are being forced on land -- and they're hungry. With the apex predators frequently turning to human junkyards for a snack, northern towns have had to get creative in order to keep both their people and wildlife safe. Biologist and conservationist Alysa McCall shares lessons from the field on how to safely navigate c…
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Episode 13: Amy Lehman of Lake Tanganyika Floating Health Clinic: Power Dynamics in Medicine and a Development Journey
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Amy Lehman is Founder and CEO at Lake Tanganyika Floating Health Clinic, an international organization, whose mission is to address the problem of healthcare access for millions of people who live in the isolated, but strategically critical lake, Tanganyika, great lakes region of central Africa. She received both an MD and MBA from the University o…
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Episode 12: Nkem Egekeze of Stealth Start-ups: Waste Not/Want Not - a Mindset for Medicine
23:41
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Nkem Egekeze is chief innovation officer and Managing Director of Stealth Startup. He previously worked as an orthopedic surgery resident and as a research scholar at the University of Georgia, and a strategy advisor at Harvard Innovation Labs. He obtained his medical degree from University of Michigan medical school. He focuses on providing value-…
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