Best CSF Podcasts (2026)

1
🧠🌊 Clearing the Brain: CSF Flow, Sleep, and Neuroimmunity 4:19

10d ago4:19

4:19

🧠💧 How does the brain clean itself—and defend itself? A landmark Neuron review unifies two once-separate stories: brain waste clearance and immune surveillance. The glymphatic system, powered by CSF flow, sleep, and vascular pulsatility, works hand-in-glove with meningeal lymphatics to clear toxins (β-amyloid, tau) and present brain antigens to the…

1
Vertebral Artery Injury Grading 11:21

32m ago11:21

11:21

Dr. Francis Deng discusses the article by Vankawala et al. entitled "Evaluating the Role of Imaging Markers in Predicting Stroke Risk and Guiding Management after Vertebral Artery Injury: A Retrospective Study." The Biffl grading scale assess blunt cerebrovascular injury severity, but its prognostic validity for vertebral artery injuries with respe…

1
🌱 Slow Starts, Strong Finishes: How Legends Are Really Made 5:38

12d ago5:38

5:38

🏆 How do world-class performers really develop? A fascinating Science review (Güllich et al., 2025) overturns a deeply held belief: early stars are rarely future legends. Across sports, science, music, and chess, peak performers often showed slower early progress, less early specialization, and more multidisciplinary practice. The lesson is lyrical…

1
Aerobic Activity as Precision Cancer Prevention 🏃‍♀️🎯🧬 3:07

13d ago3:07

3:07

🏃‍♀️ Exercise is not lifestyle advice—it's cancer biology. A landmark analysis of 443,768 adults from the UK Biobank and NHANES shows that regular aerobic physical activity (≈117–500 min/week) is associated with: • 21% lower risk of inflammation-related cancers • 34% lower all-cancer mortality Mechanistically, exercise: 🔬 Reduces chronic low-grade …

1
EU SafeHearts Plan: 🧬💓 From Genes to Gyms, ❤️ Know Your Numbers, ❤️ Stronger Hearts, Smarter Europe, Healthier Lives 5:41

13d ago5:41

5:41

🫀 Europe puts the heart first. The EU Safe Hearts Plan is a bold, evidence-based roadmap to tackle Europe's leading cause of death—cardiovascular disease—through prevention 🛡️, early detection 🔍, better treatment 🏥, smart digital tools 🤖, and a relentless focus on equity ⚖️. With clear targets (including a 25% reduction in premature cardiovascular …

1
Hormones, and Abdominal Pain 🧬🦠🔥 How Estrogen Amplifies Gut Sensitivity in Females 4:54

15d ago4:54

4:54

🧠🦠 Why does abdominal pain affect women more? Science offers a cellular answer. A new Science study uncovers an estrogen-tuned gut pain circuit in which peptide YY–secreting enteroendocrine cells activate serotonin-releasing cells, sensitizing gut sensory nerves—especially in females. Hormones, microbes, and diet converge locally in the colon to am…

1
Dr RR Baliga's Philosophical Discourses: Søren Kierkegaard (Denmark, 1813–1855 CE) – Existentialism 3:22

15d ago3:22

3:22

📚🇩🇰 Søren Kierkegaard (1813–1855): the philosopher of choice, anxiety, and becoming Kierkegaard argued that the highest human task isn't just knowing the good—it's embodying it: becoming a self through commitment, responsibility, and inwardness. His framing of "existence" as the lived work of becoming helped spark what we now call existentialism. 🧭…

1
A Molecular Autopsy in Real Time 🧬⏱️Checkpoint Inhibitors, Multiorgan Damage ♟️🧬⚠️ 3:27

16d ago3:27

3:27

🧬 When immunity saves—and harms—at the same time A striking NEJM correspondence reveals that patients receiving immune checkpoint inhibitors often sustain molecularly detectable multiorgan damage—weeks to months before symptoms appear. Using cell-free DNA methylation mapping, investigators show that immune-related adverse events are systemic, not i…

1
Same Drink, Worse Morning 🍷⏳😖Alcohol vs the Aging Clock ⏰🍸😴 3:26

17d ago3:26

3:26

🍷⏳ Why Hangovers Get Worse as We Age — Science, Not Sentiment Ever wondered why the same drink that once sparkled now punishes? A Well Informed piece from The Economist explains how aging physiology—less body water, slower metabolism, disrupted sleep, and toxic metabolites—turns modest indulgence into a morning reckoning. 🧠💤☠️ The takeaway is not a…

1
⏳➡️⏰ Can Science Make Old Immune Cells Young Again? 5:25

18d ago5:25

5:25

🧬✨ Can we make the ageing immune system young again? A fascinating Nature study shows that a three-part mRNA cocktail (DFI) can temporarily rejuvenate T cells in aged mice, improving responses to vaccines and cancer immunotherapy—without breaking immune tolerance. By turning the liver into a short-term factory for key immune signals (DLL1, FLT3L, I…

1
AI intracranial aneurysm detection feat. Babatunde Akinpelu 23:14

17d ago23:14

23:14

In this AJNR Author Interview, Dr. Francis Deng discusses with Dr. Babatunde Akinpelu the article "Assessing the Accuracy of Artificial Intelligence in Detecting Intracranial Aneurysms in a Clinical Setting Relative to Neuroradiologists." Neuroradiologists performed better than a commercial AI program for intracranial aneurysm detection in sensitiv…

1
Protein Moderation: Age Slower, Live Better 🧬⏳❤️ 5:10

19d ago5:10

5:10

🧬 Protein Restriction, Aging, and Longevity ⏳ A remarkable new study in Cell shows that moderate protein restriction—especially when started in midlife—can reprogram aging biology across 41 organs, improving metabolic and cardiovascular health. 🫀⚙️ Using deep multi-organ proteomics in mice and human plasma validation, the authors demonstrate benefi…

1
Hospitals Must Outsource Med Physics? The Truth About Healthcare's Last Fragmented Frontier 36:21

19d ago36:21

36:21

Medical physics is at an inflection point. As imaging and care delivery move rapidly into outpatient centers, ambulatory clinics, and community-based locations, the traditional in‑house physics model is being stretched beyond what it was designed to support. Jason Schneck offers a candid perspective on why this shift demands a more mobile, scalable…

1
Waves, Not Lone Rangers 🌊⚔️🧬: How Neutrophils Work Collectively 3:59

21d ago3:59

3:59

🧬 Rethinking Neutrophils: From Lone Cells to Living Systems 🧠⚔️ For over a century, neutrophils were seen as short-lived foot soldiers of immunity. This new Cell review reframes them as something far more interesting: a coordinated, adaptive collective. ✨ Key ideas: • Short-lived cells, long-term memory • Two compartments: granulopoietic + mature •…

1
🌙 Timing Is Tissue: Circadian Control of Neutrophils Limits Cardiac Damage 4:36

22d ago4:36

4:36

⏰🫀 Does the heart care about the time of day? Yes—profoundly. A new study in the Journal of Experimental Medicine reveals a circadian checkpoint in neutrophils that determines how much damage occurs after myocardial infarction. Morning ischemia triggers more injury, while nighttime CXCL12–CXCR4 signaling reprograms neutrophils, relocating them into…

1
Dr RR Baliga's Philosophical Discourses: Georg Wilhelm Friedrich Hegel (Germany, 1770–1831 CE) – German Idealism 5:24

23d ago5:24

5:24

Exploring Hegel's Vision of Progress and Freedom 🌍🔄✨ Reflecting on Georg Wilhelm Friedrich Hegel's remarkable insight that history is a dynamic journey toward greater human freedom. His dialectical lens — the idea that contradictions are not dead ends but engines of development — offers a powerful way to think about institutions, leadership, and ch…

1
Curing Cancer, Guarding the Heart 🛡️ | Cardio-Oncology Playbook-1 5:40

24d ago5:40

5:40

🫀🧬 Cardio-Oncology: where modern cancer cures meet the heart As cancer survival improves, cardiovascular toxicity has emerged as a defining challenge of our time. From BTK inhibitor–associated atrial fibrillation ⚡, to immune checkpoint inhibitor myocarditis 🔥, to VEGF-driven hypertension 🩸, the heart increasingly pays the price of precision oncolo…

1
🧬 Prediabetes: Normalize Glucose, Save Hearts, Gain Decades ❤️📉⏳❤️ 4:35

25d ago4:35

4:35

🧬 Prediabetes remission is not just metabolic—it's cardiovascular medicine. ❤️ A new analysis in The Lancet Diabetes & Endocrinology shows that achieving remission to normoglycaemia—not merely delaying diabetes—was associated with a ~50% reduction in cardiovascular death or heart failure hospitalisation, with benefits persisting for 20–30 years acr…

1
Fat, Fire, and Fibrosis 🔥🧬🛑 Unmasking the Metabolic Engine Driving MASLD 4:54

26d ago4:54

4:54

🔬 New Insights on MASLD from JAMA 🍃 I recently reviewed an excellent JAMA article on Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD)—now recognized as the most common chronic liver disease worldwide. The review highlights how metabolic dysfunction, inflammation, and fibrosis converge to drive long-term risks, including cardiovascul…

1
The Brain's Hidden Rivers, Healing Flows, Hope Ahead 10:07

25d ago10:07

10:07

In this week's exploration, I dive into the brain's hidden "plumbing"—the glymphatic and meningeal lymphatic systems—drawing from a remarkable report in Science magazine (Dec 2025). The piece outlines emerging Alzheimer's strategies ranging from VEGF-C and Aquaporin-4 gene therapy to vasomotion drugs, CO₂ breathing, massage-based lymphatic stimulat…

1
Obesity, Innovation, Action: The WHO Roadmap for GLP-1 Therapies 🌐🚀📘 5:51

28d ago5:51

5:51

🌍 New WHO Guidance on GLP-1 Therapies: A Turning Point in Obesity Care 💉📘 The latest JAMA report highlights a pivotal moment in global health: the WHO's evidence-informed guideline on GLP-1 therapies for adults living with obesity. With over 1 billion people affected worldwide, this chronic, relapsing disease demands integrated, equitable, lifelong…

1
🔥 Activated Immunity, Aggravated Coronary Plaques, Accelerated ACS 6:04

29d ago6:04

6:04

Delving into the latest JAHA review on immune checkpoint inhibitors and the heart has been illuminating 🔍❤️. As immunotherapy transforms cancer care, we're learning that unleashed T-cells can also stir the silent storms within vulnerable plaques ⚡🩺. This piece beautifully unpacks how ICIs may accelerate atherosclerosis, heighten ACS risk, and chall…

1
Dr RR Baliga's Philosophical Discourses: Immanuel Kant (Germany, 1724–1804 CE) – Critique of Pure Reason 7:19

30d ago7:19

7:19

Immanuel Kant: The Architect of Modern Reason 🧠✨ Fascinating to revisit Kant's legacy — the thinker who reshaped how we understand knowledge, morality, and human freedom. His ideas on autonomy, duty, and the categorical imperative continue to guide ethical reasoning in science, leadership, and society. From Critique of Pure Reason to Perpetual Peac…

1
📊 Detect, Diagnose, Defend: Protecting the Heart During ICI Therapy per IC-OS 🫀🧭🛡️ 5:29

1M ago5:29

5:29

🚀 Immune checkpoint inhibitors have transformed cancer care—but they come with a cardiovascular shadow. A new International Cardio-Oncology Society (IC-OS) position statement offers the clearest guidance yet on myocarditis, pericarditis, arrhythmias, ACS, and noninflammatory HF linked to ICI therapy. 🫀💡 Key insights include: • Early recognition wit…

1
From GFR to Global Health: CKD's Rising Tide 🌊📉🌐 6:03

1M ago6:03

6:03

Chronic kidney disease now affects nearly 850 million people worldwide, yet early detection and simple, evidence-based interventions can dramatically change the trajectory of both kidney and cardiovascular health. 🌍🩺 The latest Lancet Seminar highlights powerful tools—eGFR + albuminuria staging, SGLT2 inhibitors, RAS blockade, statins, and GLP-1 th…

1
📅🔍🧠: A Natural Experiment Reveals Dementia-Slowing Effects of Vaccination 3:37

1M ago3:37

3:37

🚀 New insights from Cell shine a light on an unexpected ally in the fight against cognitive decline. A natural experiment from Wales shows that the shingles (herpes zoster) vaccine doesn't just prevent viral reactivation—it may also reduce new mild cognitive impairment and lower dementia-related mortality over long-term follow-up. 🔍 Using a strict …

1
Covid, RSV, Influenza: The 2025–26 NEJM Update 🧬🔥📊 4:56

1M ago4:56

4:56

📘 New NEJM Evidence for the 2025–26 Vaccine Season is out—and it delivers clarity at a time we need it most. The systematic review of 511 studies shows strong, consistent protection against hospitalization from Covid-19, RSV, and Influenza, with reassuring safety profiles across age groups. 💉🛡️ Key insights: improved VE for updated Covid-19 strains…

1
The U.S. Is 1,500 Radiologists Short: What It Means for Imaging Workloads with Dr. Ian Weissman 41:31

1M ago41:31

41:31

Radiology is experiencing one of the most severe workforce shortages in modern history, and the effects are becoming impossible to ignore. Dr. Ian Weissman takes us through the full picture: rising imaging demand, younger and sicker patient populations, a decade of increasing CT/MRI utilization, and post‑COVID burnout that accelerated retirements a…

1
Winning Against HFrEF 🥇💓🛠 Diagnose Early. Treat with GDMT. Follow Through 5:46

1M ago5:46

5:46

New Lancet Seminar on heart failure with reduced ejection fraction. 💓📘, this videocast walks listeners through the essentials of diagnosis, natriuretic peptides, imaging pathways, and the four foundational therapies shaping modern heart failure care. It's a clear, evidence-driven journey—designed to inform, clarify, and elevate bedside practice. Tu…

1
Seeing CAD Clearly 🔍❤️: Plaque, Perfusion, Prognosis 📸💓📈 6:20

1M ago6:20

6:20

🔍💓 Chronic Coronary Artery Disease: Seeing What Matters Before It Hurts Just finished reviewing the 2025 Lancet paper on contemporary non-invasive imaging for chronic CAD, and the message is striking: how we see the heart shapes how well we save it. From CT angiography that unmasks non-obstructive plaque 🖥️➡️🫀 to stress PET/CMR that maps true ische…

1
Dr RR Baliga's Philosophical Discourses: David Hume (Scotland, 1711–1776 CE) – Skepticism and Empiricism 3:25

1M ago3:25

3:25

Exploring David Hume 🧠✨ Just revisited David Hume's extraordinary contributions to modern thought — a reminder of how deeply empiricism, skepticism, and the science of human nature shape our intellectual world. His insights on causation, the limits of reason, and the power of moral sentiment continue to resonate across philosophy, psychology, econo…

1
Heart Failure Rising 📈 | Risks Rewired 🔄 | America's 35-Year Shift 🇺🇸 4:42

1M ago4:42

4:42

The U.S. heart failure landscape is transforming—and fast. 🫀📊 A new JACC analysis reveals a 35-year shift from ischemic to metabolic drivers of heart failure, with obesity, dysglycemia, and chronic kidney disease rising sharply, even as blood pressure, cholesterol, smoking, and myocardial infarction decline. 📉⚖️ These trends demand a new generation…

1
Clocks, Clues, and Clarity ⏳🔬🧠 — Decoding Organ-Specific Aging 3:20

1M ago3:20

3:20

🧬⏳ New Insights into Organ-Specific Aging! 🧠❤️🩺 Just explored a remarkable Nature Aging study showing how organ-specific proteomic clocks can forecast disease, cognitive decline, and even longevity with impressive precision. These clocks—built from >2,900 plasma proteins—reveal that the brain, kidney, and arteries age on their own timelines, each c…

1
Vaccines. Viruses. Vital Signs. 💉🦠❤️ Adult Immunizations as Cardiovascular Prevention 4:29

1M ago4:29

4:29

Respiratory vaccines are not just infection-fighters—they're cardiovascular protectors. 💉🫀 The 2025 JACC Consensus reminds us that influenza, pneumococcal, COVID-19, RSV, and zoster vaccines reduce MI, HF decompensation, hospitalizations, and death in our most vulnerable patients. As clinicians, we hold the power to translate evidence into preventi…

1
Sun, Skin, Survival 🌞🧬🛡️ – The Modern Landscape of Keratinocyte Carcinomas 3:02

1M ago3:02

3:02

The latest JAMA article on keratinocyte carcinomas 🌞—a timely reminder that BCC and cSCC remain the world's most common cancers, with more than 5.4 million cases annually in the US alone . The review highlights essential updates in epidemiology, high-risk features, prevention, and evidence-based management, especially the role of sun protection, ac…

1
Food In, Fire Out 🍽️🔥—The Leukotriene Story 🧬 4:48

1M ago4:48

4:48

🚨 Food Anaphylaxis: New Mechanisms Unveiled 🍽️🧬 A superb NEJM review highlights how cysteinyl leukotrienes act as gatekeepers in the gut—opening antigen passages, expanding mast cells, and amplifying the risk of oral anaphylaxis. The work elegantly bridges basic lipid biology with real-world food allergy challenges, and points toward new preventive…

1
Cannabis: Promise, Peril, and Practice 🌿⚖️🧭 5:07

1M ago5:07

5:07

🌿 What does the evidence really say about medical cannabis? A new JAMA review highlights a clear message: cannabis helps few conditions—and harms may outweigh benefits for many. 📉 Small benefit for nausea ⚡ Moderate benefit for select pediatric seizures 💊 Limited evidence for pain, insomnia, or psychiatric use ❤️ Risks rise with high-potency produc…

1
Dengue Blocked, Viral Load Dropped, Hope Unlocked--High-Dose Mosnodenvir Delivers 💊🚀🛡️ 3:56

1M ago3:56

3:56

Thrilled to see a major step forward in dengue prevention! 🦟💊 A new NEJM study reports that daily mosnodenvir, a first-in-class antiviral targeting the NS3–NS4B interaction, significantly reduced DENV-3 viral load and prevented infection in a controlled human challenge model. 📉🧬 It's early, but the results offer real hope for a long-awaited oral de…

1
Storms, Syncope, Survival 🌩️😵‍💫❤️ — Long QT Syndrome update 4:46

1M ago4:46

4:46

Delighted to share a concise update on the latest NEJM review of Long QT Syndrome 🫀📘 — a masterful synthesis by Schwartz & Crotti that reframes how we recognize risk, personalize therapy, and prevent sudden death in this genetically mediated disorder. The piece highlights ion-channel biology, gene-specific triggers, the impact of modifier genes, an…

1
Sudden Sensorineural Hearing Loss 10:54

1M ago10:54

10:54

In this AJNR article summary, Dr. Francis Deng reviews a study, from corresponding author Dr. Katherine Reinshagen, entitled "Retrospective Review of MR Findings in Sudden Sensorineural Hearing Loss and Associated Clinical Features". In this large cohort, the yield of MRI for relevant findings was 5.9%, including tumors in less than 3%. The spectru…

1
Dr RR Baliga's Philosophical Discourses: Gottfried Wilhelm Leibniz (Germany, 1646–1716 CE) – Monadology 3:15

1M ago3:15

3:15

🧠✨ Leibniz: Harmony, Logic, and the Birth of the Digital Mind Celebrating Gottfried Wilhelm Leibniz — the mathematician-philosopher who co-created calculus, invented binary arithmetic, and envisioned a world stitched together by pre-established harmony. His Monadology reads like proto-systems theory, and his binary system is the quiet ancestor of e…

1
Genes, Environment, Development 🧬🌿🧠— A 2025 Perspective on Autism 5:15

1M ago5:15

5:15

🧬 New insights into autism: A 2025 JCI Viewpoint highlights how hundreds of genes, polygenic risk, and specific environmental factors converge during fetal brain development to shape autism likelihood. 🧠 Early biomarkers—from infant MRI and ERPs to machine-learning models using EHR data—are accelerating earlier, more tailored interventions. 🌱 Advan…

1
Numbness • Nerves • Nuance 🦶⚡🧠 — Decoding Peripheral Neuropathy 4:58

2M ago4:58

4:58

🔍 Peripheral Neuropathy: What Clinicians Should Know 🧠⚡ Peripheral neuropathy affects ~1% of adults worldwide, with diabetes accounting for more than half of all cases. The JAMA review highlights why length-dependent patterns dominate, how metabolic stress injures long axons first, and why sensory symptoms outpace motor loss. Evidence-based evaluat…

1
Stroke Risk, Stent Benefit, Surgical Uncertainty 🧠✨🔧 5:12

2M ago5:12

5:12

New NEJM insights on asymptomatic carotid stenosis 🧠🔍 The CREST-2 trials offer a landmark update: intensive medical therapy remains the cornerstone, while carotid stenting shows selective benefit when performed by expert operators. Endarterectomy, however, provides no significant advantage over modern medical management. With stricter blood-pressur…

1
UPFs, Diets, Disease: The Global Drift 🍔➡️🌍➡️⚠️ 6:26

2M ago6:26

6:26

The new Lancet Series on ultra-processed foods offers a striking insight: as UPFs rise globally, traditional whole-food diets decline—bringing nutrient imbalance, overeating, toxic exposures, and hyper-palatable formulations that quietly reshape health trajectories. 🍔➡️⚠️ Across more than 100 prospective studies and multiple trials, higher UPF inta…

1
Groceries, Guidance, Gains 🛒📞📉 — How DASH Delivery Lowers Blood Pressure 4:50

2M ago4:50

4:50

Home-delivered DASH-patterned groceries paired with dietitian counseling meaningfully lowered blood pressure and LDL cholesterol among Black adults living in food deserts 🥗📉—as demonstrated in the GoFresh randomized trial (JAMA). An accompanying editorial highlights why future "food-as-medicine" programs must prioritize underconsumed, health-promot…

1
Why Medical Physicists Are Drowning in Level 1 Tasks (And What It Means for AI Adoption) 44:46

2M ago44:46

44:46

Why are medical physicists, some of the most highly trained problem-solvers in healthcare, drowning in basic, repetitive regulatory work? In this conversation, Dr. Thomas Griglock breaks down the systemic challenges behind Level 1 task overload, from equipment testing to compliance workflows. He explains how the increasing volume of imaging studies…

1
Hemodialysis, Cardiovascular Burden, Therapeutic Hope 🩺❤️🌊 — Can Omega-3 Fatty Acids Bend the Risk Trajectory? 4:57

2M ago4:57

4:57

🩺 New insights in hemodialysis care. A major New England Journal of Medicine study reports that daily supplementation with long-chain omega-3 fatty acids (eicosapentaenoic acid and docosahexaenoic acid) led to a 43% reduction in serious cardiovascular events among adults receiving maintenance hemodialysis. 🐟💙 In a population where traditional cardi…

1
💊 Oral, Potent, Proven — Enlicitide Redefines LDL Control 7:03

2M ago7:03

7:03

🚀 A milestone moment in lipid therapeutics! The new JAMA trial on the oral PCSK9 inhibitor Enlicitide reports a ~60% reduction in LDL-C, with parallel decreases in ApoB and Lp(a)—all on top of maximally tolerated statin therapy. For individuals with heterozygous familial hypercholesterolemia (HeFH)—where reaching LDL targets remains a persistent ch…

1
One Cup of Coffee. Less Atrial Fib/Flutter. More Life ☕🌀➡️💛 3:07

2M ago3:07

3:07

☕ DECAF Trial insight! A new JAMA study shows that daily caffeinated coffee may lower recurrence of atrial fibrillation compared with abstinence. Patients drinking ~1 cup/day had 47% recurrence vs 64% with abstinence (HR 0.61, p=0.01) 📉💓 No major safety concerns—challenging long-held beliefs that coffee is proarrhythmic. 💡Takeaway: For many patient…

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