Dementia Matters is a podcast about Alzheimer‘s disease and other causes of dementia. Host Dr. Nathaniel Chin interviews leading scientists and caregiving experts to bring listeners the latest in Alzheimer’s disease news, research and caregiver resources. Brought to you by the Wisconsin Alzheimer’s Disease Research Center, find show notes and more resources at adrc.wisc.edu/dementia-matters.
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Welcome to The Brain Trust, a podcast for and by physicians designed to help improve screening, diagnosis, and treatment of Alzheimer’s disease and related dementias in clinical workflows. Tune in weekly to hear our guest primary care clinicians discuss innovative ways to support patients and their families in better managing brain disease.
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The Iowa Geriatric Education Center GeriaCast podcast covers a wide range of topics in the clinical management of older adults. It is of particular value and importance to health practitioners who work with older adults.
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How can you improve lives within your community? How do you solve real problems around you? Hear from people who took matters into their own hands, to help those around them through innovative initiatives with social purpose. Find out how social entrepreneurs drive impact to make a difference. This podcast is by Expo Live, produced by Kerning Cultures Network.
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REVEALing APOE Results: Making Genetic Disclosures in Alzheimer’s Research
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On this episode of Dementia Matters, Dr. Scott Roberts talks about disclosing genetic test results for APOE, a gene that can increase one’s likelihood of developing Alzheimer’s disease. While this information can be concerning, Dr. Roberts shares that it can empower individuals to take the necessary precautions to lower their risk of developing the…
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Advocating for All: The Impact of Community and Equity in Dementia Research
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Dementia Matters Special Series: Voices of Research Participants What do you do when dementia symptoms begin to upend your entire life? For Brother John-Richard Pagan, the answer was to persist in finding a diagnosis and a supportive community that aligned with his values. In this episode of our Voices of Research Participants series with co-host S…
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The Brain Trust Episode 24: Primary Care Summary: Early Detection and Diagnosis of Alzheimer's Disease
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In today's episode, hosts Dr. Raj Shah and Dr. Eukesh Ranjit revisit foundational lessons on Alzheimer's diagnosis, stressing the importance of practical techniques and understanding the critical role of office staff and caregivers in recognizing early signs. Primary Care physicians gain insights into evaluating cognitive issues, medication lists, …
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Be BOLD: Detecting Dementia Early Through Public Health Initiatives
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When it comes to dementia diagnoses, the earlier, the better, but why is it difficult to detect dementia in its early stages? Moreover, what strategies can be used to improve dementia detection? Dr. Josh Chodosh joins the podcast to answer these questions and discuss how public health initiatives could improve dementia diagnoses. He also talks abou…
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The Brain Trust Episode 23: The Caregiver Mini-Series #5 Jeanne
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In today’s episode host Raj Shah, MD is joined by Susan Frick, MSW, LSW, Social Worker, Rush Alzheimer’s Disease Center, to talk with caregiver Jeanne as she shares her heartrending experience recognizing her husband John's early signs of Alzheimer's. Jeanne talks about profound changes to simple tasks, like dressing and driving, when faced with th…
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Let’s Talk: Navigating Family Conversations About Dementia Through Shared Decision-Making
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Picture this: you are supporting someone experiencing memory changes as a clinician, support person or care partner while they go through the memory clinic process. How do you navigate the challenging conversations surrounding symptoms, diagnoses, care plans and more that come up? Dr. Toby Campbell joins the podcast to discuss the importance of sha…
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Making an IMPACT: Advancing Alzheimer’s Disease Clinical Trials Through Workforce Development and Inclusivity
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Advances in Alzheimer’s disease clinical trials are accelerating rapidly, leading to new insights and disease-modifying therapies, but how does the field continue bolstering that momentum? For Dr. Rema Raman, it’s through improving inclusivity and training for early-career researchers. Recorded at the 2024 Alzheimer’s Disease & Related Dementias Re…
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Living with Lewy Body: A Neurologist’s Journey Through Research and Dementia Care
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What do you do if you have a family history of dementia and are experiencing symptoms, but can’t get a diagnosis? Dr. Sara Langer has dealt with just that. In the latest episode of our Voices of Research Participants series, Dr. Langer shares the obstacles she endured to receive her diagnosis of Lewy body dementia (LBD), how her background as a neu…
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The Fundamentals of Neuropsychology: Breaking Down Cognition, Memory and More
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The brain is the most complex part of the human body, controlling thought, memory, emotion, motor skills, sensory input and all the processes that regulate our bodies. How exactly does it work, and how are clinicians able to determine whether brain changes are a result of normal aging, Alzheimer’s disease, or something else? Dr. Victoria Williams j…
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Since the COVID-19 pandemic was declared by the World Health Organization (WHO) in 2020, there have been many concerns about how cases of COVID-19 and Long COVID or Post-COVID Conditions (PCC) affect not just a person’s physical health, but their cognition as well. In this episode, Dr. Jim Jackson talks about his path into critical illness research…
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Listen Up! The Connections Between Hearing Loss, Hearing Interventions and Cognitive Decline
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Hearing loss affects roughly 15.5% of Americans 20 years and older. While the majority of these individuals experience mild hearing loss, the prevalence and severity of hearing loss increases with age. What does this sensory change mean for dementia risk, and can this risk be prevented through interventions like hearing aids? Dr. Frank Lin joins th…
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The Brain Trust Episode 20: The Caregiver Mini-Series #2 James
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When your world revolves around the delicate balance of caring for a loved one with Alzheimer's, each day can bring a torrent of emotions and challenges. That's the reality James Litchfield faced when his father, Buddy, was diagnosed with early-onset Alzheimer's. Host Dr. Raj Shah and Susan Frick from the Rush Alzheimer's Disease Center talk about …
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The Brain Trust Episode 22: Caregiver Mini-Series #4 Leslie
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When Leslie first noticed her husband Phil's memory lapses and moments of disorientation, little did she know that these were signs of younger-onset Alzheimer's disease. In our heartfelt discussion with Leslie, Dr. Raj Shah and social worker Susan Frick, traverse the intricate realities of early signs of Alzheimer's. Leslie discusses the day-to-day…
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The Brain Trust Episode 21: Caregiver Mini-Series #3 Donna
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When Donna's husband, Scott, began showing signs of young-onset Alzheimer's, their world turned upside down. Their story, shared with raw honesty in our latest podcast episode, brings to light the harsh reality of seeking an accurate diagnosis for Alzheimer's, particularly in younger individuals. Their journey through a maze of dismissive attitudes…
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From Caregiver to Research Participant: How One Woman’s Experience as a Dementia Caregiver Drew Her to Alzheimer’s Research
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Caring for a loved one with cognitive decline can be challenging. While it is a labor of love, burnout is all but inevitable. In this episode kicking off our Voices of Research Participants series with co-host Sarah Walter, Cynthia Sierra touches on her personal experience with caregiver burnout as both a caregiver and research study partner for he…
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The Brain Trust Episode 19: Caregiver Mini-Series #1 Katrina
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The Brain Trust Caregiver Mini-Series brings you into the quiet strength of Alzheimer's/Dementia care partners, as Dr. Raj Shah and social worker Susan Frick from the Rush Alzheimer's Disease Center guide us through the delicate tapestry of caregiving. When the familiar fabric of life begins to unravel with the onset of Alzheimer's, it falls on the…
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Looking at Lecanemab’s Eligibility Guidelines and Prescription Process
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In the past few years, new therapies shown to slow the progression of Alzheimer's disease in people in the early stages of the disease have been making their way through the U.S. Food and Drug Administration’s (FDA) approval process. With these treatments now available, there are a growing number of questions surrounding who is eligible to take the…
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Do Non-Medicinal Interventions Reduce Dementia Risk? Studies are Inconclusive, Here’s Why
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In 2017, the National Academies of Sciences, Engineering, and Medicine published a report showing promising but inconclusive evidence suggesting that interventions like cognitive training, blood pressure control and increased physical activity reduce a person’s risk for dementia, but what does the research show now? Dr. Luke Stoeckel from the Natio…
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The Road to Hope: Philanthropy’s Impact on Alzheimer’s Research
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In this year-end episode of Dementia Matters, we explore the vital role of philanthropy in advancing Alzheimer's disease research and care. Mr. Dave Adam serves on the board of visitors for the UW Initiative to End Alzheimer’s (IEA) and is an avid long-distance biker. In this episode, Adam shares his journey of combining his passions for biking and…
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The Brain Trust - Episode 18: Alzheimer's Disease and Related Dementias in African American Communities
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In our latest Brain Trust podcast episode, Dr. Raj Shah chats with Dr. Tonja Austin, family physician and assistant professor from Rush University. Dr. Austin shares her valuable insights, stemming from her extensive, frontline experience within the African-American community in an area commonly referred to as Illinois Southland. They delve into th…
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Could Green Tea Hold the Key to New Alzheimer’s Treatments?
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Dr. Paul Seidler joins the podcast to discuss his recent study looking at the connection between molecules in green tea and tau proteins. He also discusses the impact those molecules have on preventing cognitive decline and how these findings could lead to new strategies for treating Alzheimer’s disease. Guest: Paul Seidler, PhD, assistant professo…
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The Impact of Social Isolation on Dementia Risk in Older Adults
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In May 2023, the U.S. Surgeon General, Dr. Vivek Murthy, released an advisory calling attention to the public health crisis of loneliness and social isolation in the U.S. With this widespread issue affecting such a broad population, how does social isolation impact older adults? Dr. Alison Huang joins the podcast to share insights from her study on…
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Memories and Milestones: Celebrating Six Years of ‘Dementia Matters’
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Six years following the start of Dementia Matters in October 2017, the podcast team turns the tables on our host, Dr. Nathaniel Chin. Producers Amy Lambright Murphy and Caoilfhinn Rauwerdink talk with Dr. Chin about how the podcast got started, the brain health tips he incorporates into his own life, how he envisions the field of Alzheimer’s diseas…
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The Brain Trust - Episode 17: Advancing Dementia Detection with Community Health Workers
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Connecting Primary Care Practices with Community Health Workers: Advancing Early Detection and Diagnosis of ADRD. Join hosts Raj Shah, MD and Eukesh Ranjit, MD as they discuss the importance of connecting Primary Care Practices with Community Health Workers to advance early detection and diagnosis of ADRD. They chat with Tracey Smith, Director of C…
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Crosswords or Computers: Which is Better for Cognitive Engagement?
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Cognitive engagement is vital to keeping your brain healthy since it can slow shrinkage and induce neuroplasticity. While modern technology offers many new tools and games to keep your brain active, are they better than traditional puzzles like crosswords? Dr. Murali Doraiswamy of Duke University joins the podcast to talk about his recent study, in…
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The Brain Trust- Episode 16: Dare to Care about Early ADRD Detection
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Special episode with Dare To Care radio show connecting social workers, community members and primary care physicians on the importance of efforts being made across the state in the early detection and treatment of Alzheimer’s disease and related dementias. We invite you into the world of the Dare to Care program and the Brain Trust initiative this…
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RAISE(ing) Support for Caregivers: State and National Resources for Family Care Partners
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Dementia caregiving is a multifaceted domain, deeply influenced by research, strategy and personal experiences. How are these elements shaping the current and future landscape of care? Dr. Beth Fields joins the podcast to discuss strategies and resources for caregivers from both national, state and personal perspectives, including the CHAT tool, th…
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Mental Health and Memory: The Connections between Chronic Mental Illness and Dementia
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Like cognition, mental health is a key component of the brain — and overall — health. In what ways can mental health and chronic mental illness impact a person’s cognition and risk for dementia? Dr. Art Walaszek joins the podcast to discuss the relationships between dementia and chronic mental illnesses, including major depression, bipolar disorder…
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Highlights from the 2023 Alzheimer’s Association International Conference
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The 2023 Alzheimer's Association International Conference (AAIC) in Amsterdam brought together the world's leading scientists, clinical researchers, early career investigators, caregiving researchers and more to discuss the latest findings and advancements in dementia science. Dr. Percy Griffin joins the podcast to share key highlights from the con…
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The Brain Trust - Episode 15: Early Diagnosis in the New ADRD Treatment Era
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In today’s episode host Raj Shah, MD chats with Avinash Mantha, MD, Associate Program Director at Loyola Hines VA Geriatric Fellowship, to discuss the adaptations primary care will need to make with the introduction of new ADRD treatment modalities. Learning Objectives: •Describe one reason why current processes for early ADRD diagnosis will have t…
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The Brain Trust - Episode 14: Caregiver Support in ADRD Early Detection
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Discussion on ways physicians can improve early detection of Alzheimer’s disease by leveraging caregiver support Learning Objectives: Identify opportunities to guide caregivers and families of persons with dementia to appropriate care and support resources. Describe the ways a Care Consultation can be beneficial to families dealing with Alzheimer’s…
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A Fair Fight Against Alzheimer’s: The Need for Equity in Dementia Research and Care
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How can we ensure that all communities are represented in Alzheimer’s and related dementias research and have access to the latest treatments and interventions? Dr. Carl Hill, the chief diversity, equity and inclusion (DEI) officer for the Alzheimer's Association, joins the podcast to delve into the significance of representation, diversity, equity…
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Agitation and Alzheimer’s: Strategies for Managing Behavioral and Psychological Symptoms of Dementia
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Many people living with dementia experience behavioral symptoms alongside changes in their cognition. What can care partners and healthcare providers do to manage these behavioral changes? After leading the Wisconsin Alzheimer’s Disease Research Center’s (ADRC) annual Dr. Daniel I. Kaufer Lecture, Dr. Helen Kales joins the podcast to discuss agitat…
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Promises to Practice: Creating Sustainable Community Partnerships to Support Alzheimer’s Research
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Gina Green-Harris joins the podcast to discuss the importance of collaborating with communities in Alzheimer’s research. Sharing her experience as a researcher with the Wisconsin Alzheimer’s Institute (WAI) and the All of Us research program, she describes the key tenets of community engagement and explains ways researchers can build intentional, s…
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Study Shows APOE Gene Affects Hispanic Populations’ Risk of Cognitive Decline Differently to Non-Hispanic Populations
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The APOE gene is recognized as a significant genetic risk factor for cognitive decline, with different alleles, like APOE e2, being seen as protective against decline and others, like APOE e4, indicating an increased risk for cognitive decline. However, new studies are looking at whether these trends are universal across different racial and ethnic…
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Putting Lecanemab into Practice: A Clinician’s Perspective on the New Alzheimer’s Treatment
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On July 6, 2023, the U.S. Food and Drug Administration (FDA) granted full approval for the Alzheimer’s disease drug Leqembi (lecanemab-irmb), the first medicine shown to delay the course of the disease. Having gone through a rigorous approval process, the medication exemplifies a critical advancement in the ongoing battle to treat Alzheimer’s disea…
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The Brain Trust - Episode 13: Electronic Health Record Utilization in ADRD Early Detection
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Leveraging Health IT and your Electronic Health Record (EHR) for managing and detecting patients at risk for Alzheimer’s Disease and Related Dementias. Learning Objectives: Describe tools that can be used to screen for dementia, discreetly stored within the EHR and tracked over time. Discuss future directions and the use of AI for the early detecti…
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The Brain Trust - Episode 12: Early Detection in Latino Communities
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In today’s episode host Raj Shah, MD chats with Evelyn Figueroa, MD to discuss ways family physicians can improve early detection of Alzheimer’s disease in their Latino patients. Learning Objectives: Describe specific challenges affecting the Latino communities that exacerbate the burden of Alzheimer’s disease. Name one way family physicians can cr…
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Deciding to Donate: Barriers and Benefits of Brain Donations for Diverse Populations
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Dr. Crystal Glover, health equity in aging researcher at Rush Alzheimer’s Disease Center, joins the podcast to discuss the importance of increasing brain donations and tissue samples from older adults of underrepresented backgrounds. Dr. Glover talks about the reasons why participants may be interested in brain donations, the barriers that they may…
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Lecanemab, Clinical Trials, and the Importance of Clinical Meaningfulness
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On June 9, 2023, the Food and Drug Administration’s (FDA) advisory committee unanimously voted to approve lecanemab, moving the treatment one step closer to full FDA approval. In the lead up to the FDA’s official announcement expected in early July, Dr. Paul Aisen joins the podcast to discuss Alzheimer’s disease clinical trials. Aisen, the founding…
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Understanding the Social Determinants of Health and Disparities in Alzheimer’s Research
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Dr. Lisa Barnes joins the podcast to discuss her research focusing on how social determinants of health, specifically racial differences, affect chronic diseases of aging.She explains the difference between equality, equity and justice, and the different drivers of disparities within the medical field. This episode is part of a series featuring spe…
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The Brain Trust - Episode 11: Neurocognitive Disorders
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In today’s episode host Eukesh Ranjit, MD talks with Denise Feil, MD, MPH Director of Geriatric Psychiatry Training and Education at Greater Los Angeles VA Healthcare Center, about distinguishing differences of early signs, symptoms, and behaviors in neurocognitive disorders. Learning Objectives: Describe early signs and symptoms of a neurocognitiv…
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Take Care of Your MIND: Reviewing the MIND Diet for Healthy Brain Aging
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To mark National Mediterranean Diet Month, Dr. Nathaniel Chin discusses a recent National Institute on Aging-funded study that suggests the MIND and Mediterranean diets — both rich in vegetables, fruits, whole grains, olive oil, beans and fish — are associated with fewer signs of Alzheimer’s disease in the brains of older adults. In this special ep…
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The Brain Trust - Episode 10: Early Detection of Dementia in Veteran Populations
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In today’s episode host Raj Shah, MD chats with Avinash Mantha, MD, Associate Program Director at Loyola Hines VA Geriatric Fellowship, to discuss early detection of dementia in veteran populations. Learning Objectives: Describe three potentially reverse causes of early dementia Describe the VA's multidisciplinary and collaborative care approach wi…
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The National Strategy for Diversifying Alzheimer’s Research
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Dr. Sarah Biber, the program director for the National Alzheimer’s Coordinating Center (NACC), joins the podcast to discuss efforts to increase representation and equitable practices across the 37 Alzheimer’s Disease Research Centers (ADRCs). She discusses key disparities in Alzheimer’s disease research, why diversity and inclusion are imperative i…
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The Brain Trust - Episode 9: Community Service Agencies in Rural Areas
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In today’s episode Eukesh Ranjit, MD speaks with guests Sharon Smaga, MD, Heather Knutt, and Becky Salazar to discuss the roles community service agencies can play in assisting physicians in rural areas with early detection. Learning Objectives: Describe benefits of healthcare providers connecting with community service workers around early detecti…
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The Future of Neuroscience: Early-Career Researchers Named ’One to Watch’ by the Alzheimer’s Association
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Recorded live from the Wisconsin ADRC’s Alzheimer’s Disease & Related Dementias Research Day, Dr. Nathaniel Chin discusses the importance of mentorship and the future of neuroscience and Alzheimer’s disease research with the Alzheimer’s Association International Conference® (AAIC) Neuroscience Next 'One to Watch' award recipients and the event’s or…
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The Brain Trust - Episode 8: Early Detection in FQHC’s
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In today’s episode Raj Shah, MD speaks with guest Emma Daisy, MD to discuss the roles Illinois physicians working in Federally Qualified Health Centers can play in the early detection and diagnosis of Alzheimer’s disease and related dementias Learning Objectives: Understand the roles Illinois physicians working in Federally Qualified Health Centers…
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Studies Look at Generational Differences and Associations between Cognition, Sensory Changes and Blood Biomarkers
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Dr. Natascha Merten joins the podcast to discuss her study focused on trends in cognitive function across generations. Merten also explains her research on the associations between sensory and motor functions and blood-based biomarkers for neurodegeneration and dementia. Guest: Natascha Merten, PhD, MS, director, Beaver Dam Offspring Study-Neurocog…
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The Brain Trust - Episode 7: Early Detection in African American Populations
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In today’s episode we will be discussing ways family physicians can improve early detection of Alzheimer’s disease in their African Americans patients. Learning Objectives: (1) Describe one barrier to greater early detection of Alzheimer’s disease and related dementias faced by African American patients. (2) Describe ways family physicians can impr…
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