Best Marcus Harrington Podcasts (2024)

1
Enormocast 289: Smith Curry – A Climber Boy Can Survive

22m ago

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On Episode 289 of the Enormocast, I connect to Nashville, TN to talk to climber and musician Smith Curry. Smith is one of the busiest session players in Music City on dobro and pedal steel. He also happens to be a veteran climber with big walls, first ascents, and alpine gnar under his harness-belt. Smith … Continue reading "Enormocast 289: Smith C…

1
Tackling "The Delivery Problem" of Gene Editing-Based Medicines with Mammoth Biosciences' Lucas Harrington 21:01

6d ago21:01

21:01

We love to hear from our listeners. Send us a message. Lucas Harrington, Co-Founder and Chief Scientific Officer of Mammoth Biosciences, joins Erin Harris to shed light on the biotech's proprietary ultracompact CRISPR systems to develop potential long-term curative therapies for patients with life-threatening and debilitating diseases. They discuss…

1
Enormocast 288: Don McGrath – The Vertical Mind Returns 1:05:58

3d ago1:05:58

1:05:58

On Episode 288 of the Enormocast, I reunite with Don McGrath, the author of the book Vertical Mind. Don appeared nearly a decade ago on the podcast, and his book on the mindset of climbing has never left the conversion. Don has spent the last 10 years learning even more about overcoming the hurdles our … Continue reading "Enormocast 288: Don McGrat…

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TILs for the Treatment of Solid Tumors with KSQ Therapeutics' Micah Benson, Ph.D. 35:30

9d ago35:30

35:30

We love to hear from our listeners. Send us a message. KSQ Therapeutics' CSO, Micah Benson, Ph.D., joins Erin Harris to discuss how Tumor-Infiltrating Lymphocytes (TILs) as a treatment modality have the potential to treat a variety of solid tumor types. Benson explains KSQ's Phase 1/2 clinical study, KSQ-001EX, which consists of TILs in which the S…

1
Enormocast 287: Mo Beck – A Certain Version of Fine 1:29:41

22d ago1:29:41

1:29:41

On Episode 287 of the Enormocast, I connect with Paraclimbing champion, Mo Beck. Mo was born with one hand, and her parents were determined to make sure she was ready for challenges of life like any other kid. When Mo ran into a camp counselor that told her that she didn’t HAVE TO climb if … Continue reading "Enormocast 287: Mo Beck – A Certain Ver…

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Synthetic Biology and Programmable mRNA with Strand Therapeutics' Jake Becraft 27:52

23d ago27:52

27:52

We love to hear from our listeners. Send us a message. Strand Therapeutics' CEO and Co-Founder Jake Becraft joins Erin Harris to discuss genetic regulation and how the company's programmable mRNA constructs combine genes for self-replication derived from RNA viruses with genetically programmed logic circuits that control the location, timing, and i…

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Enormocast 286: Didier Berthod – Facing the World (Part 1) 1:27:48

1M ago1:27:48

1:27:48

On Episode 287 of the Enormocast, I connect through to America’s hat with Swiss crack-master, Didier Berthod. You might have heard about Didier from his recent send of Cobra Crack. The media mentions Didier disappearing from climbing for 10 years, returning to slay the Cobra, yada, yada, but that Didier’s completion of the Cobra has … Continue read…

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Enormocast Tweener: Didier Berthod – Facing the World (Part 2) 55:38

1M ago55:38

55:38

In the early 2000s, Didier Berthod was the best crack climber in the world, then he dropped out of climbing and essentially disappeared from the world. When we left Didier Berthod in Facing the World Part 1, he had emerged from monastic life, contacted the daughter he had never seen, and returned to climbing. In … Continue reading "Enormocast Tween…

1
Developing an mRNA Therapy for DMD with Elixirgen Therapeutics' Aki Ko 14:52

1M ago14:52

14:52

We love to hear from our listeners. Send us a message. Elixirgen Therapeutics' Aki Ko joins Erin Harris to detail the company's Bobcat mRNA therapeutic and how it differs from traditional exon-skipping drugs and AAV-microdystrophin in treating DMD. Regarding delivery, Ko explains the advantage of the mRNA approach over the AAV approach.…

1
The Current State of the Global Regulatory Landscape with ISCT's Dr. Bambi Grilley 25:21

2M ago25:21

25:21

We love to hear from our listeners. Send us a message. Dr. Bambi Grilley is Professor of Pediatrics and the Director of Clinical Research and Early Product Development for the Center of Cell and Gene Therapy (CAGT) at Baylor College of Medicine AND she is Chief Regulatory Officer at ISCT. Dr. Grilley talks to us about her role as CRO at ISCT and th…

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Dr. Bruce Levine on ISCT and the Future of CAR-T 31:49

2M ago31:49

31:49

We love to hear from our listeners. Send us a message. In anticipation of ISCT 2024 in Vancouver, Canada, Dr. Bruce Levine is back on Cell & Gene: The Podcast to share information about the event as well as his expertise on the future of CAR-T therapy for solid tumors, autoimmune disease, and more. He talks about his time and learnings as President…

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Enormocast 285: Nico Favresse – Mad to Live 1:38:27

2M ago1:38:27

1:38:27

On Episode 285 of the Enormocast, after long last, I connect with Belgian rock-climber and alpinist, Nico Favresse. Nico is certainly a contender for the most experienced expedition rock-climber of all time. Perhaps only rivalled by his ubiquitous partner, Sean Villanueva-O’Driscoll? Nevertheless, Nico is an all-arounder who has tackled the biggest…

1
CGTs for HIV Suppression with Addimmune's Dr. Marcus Conant 18:51

2M ago18:51

18:51

We love to hear from our listeners. Send us a message. Dr. Marcus Conant is CMO at Addimmune, a biotech startup developing a cell therapy for HIV that spun out of cell and gene therapy biotech American Gene Technologies (AGT). He spent his career on the front lines of HIV treatment and research and remains an advocate for the HIV patient. He formed…

1
Inside BlueRock Therapeutics' Parkinson's Disease Trial with Dr. Ahmed Enayetallah 29:39

3M ago29:39

29:39

We love to hear from our listeners. Send us a message. BlueRock Therapeutics' SVP Head of Development, Dr. Ahmed Enayetallah, joins Cell & Gene: The Podcast Host, Erin Harris, to discuss the company's phase I clinical trial for Parkinson’s disease, which continues to show positive trends at 18 months. They cover the important role induced pluripote…

1
Why I Run Special: Nims Purja – I run to achieve my goals 23:53

3M ago23:53

23:53

In this special one-off episode ahead of the 2024 Wings for Life World Run on May 5, Why I Run host Ayo Akinwolere sits down with the awe-inspiring Nims Purja. Nims is an ex-Ghurka and one of the world’s best mountaineers. He’s achieved some incredible physical feats – including summiting the world’s 14 tallest mountains at record-breaking speeds. …

1
Reducing the Disease Burden of AML with Vor Bio's Dr. Robert Ang 23:08

3M ago23:08

23:08

We love to hear from our listeners. Send us a message. In 2021 on Episode 13, Vor Bio’s President and CEO, Dr. Robert Ang shared data about the company’s lead engineered hematopoietic cell (eHSC) product candidate. Dr. Ang is back to talk to Cell & Gene: The Podcast Host, Erin Harris, about how Vor has treated 8 patients demonstrating clinical proo…

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Enormocast 284: Emma Twyford – Getting on With It 1:25:41

3M ago1:25:41

1:25:41

On Episode 284 of the Enormocast, we connect across the pond to North Wales in the U.K. and into the living room of Emma Twyford. Emma is a pioneering woman in that rarified air of hard, desperate trad that only the old country can serve up. She is the first British woman to climb 9a … Continue reading "Enormocast 284: Emma Twyford – Getting on Wit…

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Enormocast 283: Clint Helander – To Live in Hearts We Leave Behind 1:16:17

3M ago1:16:17

1:16:17

On Episode 283 of the Enormocast, I sit down in a hotel in Munising, Michigan at the Michigan Icefest with Alaska-based alpinist, Clint Helander. What with the Chris Kalous Dance Party and the last call nightcap(s) at a bar literally called Whisky Dick’s, it had been a long night and an early morning for both … Continue reading "Enormocast 283: Cli…

1
Reducing Toxicities in Allogeneic Cell Therapies with Orca Bio's Dr. Scott McClellan 19:37

4M ago19:37

19:37

We love to hear from our listeners. Send us a message. Orca Bio's CMO, Dr. Scott McClellan, joins Erin Harris on this episode of Cell & Gene: The Podcast to discuss how and why toxicities continue to stymie allogeneic cell therapies. They cover Orca Bio's plan to potentially lowering the risk of GvHD as well as Orca-T, the investigational high-prec…

1
Enormocast 282: Natalia Grossman – The Tyranny of Expectations 54:32

4M ago54:32

54:32

On Episode 282 of the Enormocast, I sit down with US Olympic qualifier, Natalia Grossman. That’s right, Natalia is headed to Paris to represent the US in Lead and Boulder combined (speed is separate this time around). But this moment was caught during a bit of down time for Natalia as she ramps up for … Continue reading "Enormocast 282: Natalia Gro…

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Enormocast Tweener: Harvey Wright Returns with Patio Pacifica 56:48

4M ago56:48

56:48

On this in-between episode of the Enormocast, Harvey Wright from Episode 222 returns to discuss his ongoing treatment and recovery for addiction. But more importantly, Harvey is here to talk about his new album, Patio Pacifica, written almost entirely while in a Vancouver treatment facility. Also, we talk about the rough and dirty years since … Con…

1
Inside Cellular Rejuvenation Therapies for Age-Related Diseases with Life Biosciences' Sharon Rosenzweig-Lipson, Ph.D. 17:17

4M ago17:17

17:17

We love to hear from our listeners. Send us a message. On this episode of Cell & Gene: The Podcast, Host Erin Harris talks to Life Biosciences' CSO, Sharon Rosenzweig-Lipson, Ph.D., about the Boston-based biotech's cellular rejuvenation therapies for the treatment of age-related diseases. They cover Life Biosciences' lead program, a gene therapy ca…

1
Enormocast 281: Jon Hawk and Tye Liggins of Memphis Rox – Peace Above All 1:20:03

4M ago1:20:03

1:20:03

On Episode 281 of the Enormocast, Jon Hawk and Tye Liggins from Memphis Rox join to discuss the mission of the famous pay-what-you-can gym, Memphis Rox, in the inner-city of Memphis, TN. Jon is director of operations, and Tye went from walk-in to head coach and course-setter. Memphis Rox, founded by Tom Shadyac in 2018, … Continue reading "Enormoca…

1
The Future of Rare Diseases with The Jackson Laboratory’s Rare Disease Translational Center's Cat Lutz 27:31

5M ago27:31

27:31

We love to hear from our listeners. Send us a message. Rare Disease Day is February 29, 2024, and in honor of this important day, Cell & Gene: The Podcast Host Erin Harris sits down with Jackson Laboratory’s (JAX) Rare Disease Translational Center (RDTC)'s VP, Cat Lutz. They discuss RDTC's mission, the specific qualifications that make up a rare di…

1
Inside Yescarta's Reduced Median Turnaround Time with Kite, a Gilead company's Christopher McDonald 20:48

5M ago20:48

20:48

We love to hear from our listeners. Send us a message. On this episode of Cell & Gene: The Podcast, Christopher McDonald, Global Head of Technical Operations at Kite, a Gilead company, talks to Host Erin Harris about Kite's recent FDA approval of manufacturing process change resulting in reduced median turnaround time for Yescarta. They talk throug…

1
Enormocast 280: Taps 2024 – The Really Bollocks Edition 2:23:32

5M ago2:23:32

2:23:32

On Episode 280 of the Enormocast we present the 2024 Taps edition of the Enormocast. This is the annual episode where we lay to rest traditions, foibles, and notions in climbing that are either sadly going to sleep never to reawaken, or should be put to bed for good. The Enormocast is joined by our … Continue reading "Enormocast 280: Taps 2024 – Th…

1
Pricing, Value, And Access of CGTs With The Dedham Group's Jennifer Klarer, M.Sc.Eng. 37:17

6M ago37:17

37:17

We love to hear from our listeners. Send us a message. The Dedham Group's Jennifer Klarer, M.Sc.Eng., Partner and Head of Cell & Gene Therapy, joins Erin Harris on this episode of Cell & Gene: The Podcast for a deep dive into pricing and value for CGTs. Klarer shares a detailed breakdown of the most misunderstood aspects of cell and gene therapy pr…

1
Enormocast 279: David Smart and Royal Robbins – Some Work of Noble Note 1:34:51

5M ago1:34:51

1:34:51

On episode 279 of the Enormocast, we have an allt-ime double-header. First, David Smart joins from Toronto to talk about his life as a climber and his new book from The Mountaineers, Royal Robbins: The American Climber. Royal Robbins was one of the most influential climbers of all time, and David’s book is the most … Continue reading "Enormocast 27…

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Breaking Down Solid Tumors with Triumvira Immunologics' Dr. Paul Lammers 21:33

6M ago21:33

21:33

We love to hear from our listeners. Send us a message. Paul Lammers, M.D., M.Sc., CEO of Triumvira Immunologics joins Cell & Gene: The Podcast to talk to Host Erin Harris about TAC, the company's proprietary T cell Antigen Coupler, which has both autologous and allogeneic approaches. They also discuss targeting relapsed or refractory HER2-positive …

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Enormocast 278: Thomas Bukowski – A Funny Little Life 1:20:37

6M ago1:20:37

1:20:37

On Episode 278 of the Enormocast, I connect with Thomas Bukowski from my home to his van sitting in Yosemite. Thomas had just completed three El Cap routes in three days, and was recovering. His next adventures in Patagonia were just on the horizon. Thomas is an American citizen, but is also half Chinese and … Continue reading "Enormocast 278: Thom…

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Enormocast Rebroadcast: Episode 93: Armando Menocal – The Peaceful Climbing Warrior 1:22:21

6M ago1:22:21

1:22:21

As we stare down into the howling void of Government regulation of our dear sport, let us give thanks and a listen to Armando Menocal from 2015. Armando has made it his life’s work to keep the simpering bureaucrats in Washington and elsewhere at bay. But lately, they have reared their heads in an attempt … Continue reading "Enormocast Rebroadcast: …

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4 Keys to Allo in 2024 with Poseida Therapeutics' Kristin Yarema, Ph.D. 31:59

7M ago31:59

31:59

We love to hear from our listeners. Send us a message. Kristin Yarema, Ph.D., CEO, Poseida Therapeutics sits down with Cell & Gene: The Podcast Host Erin Harris to discuss four of the biggest challenges the CGT sector faces when it comes to the development of off-the-shelf therapies. Kristin shares how 2024 might see some real progress in allogenei…

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Enormocast 277: Kurt Smith – The Iconoclast 2:13:48

7M ago2:13:48

2:13:48

On Episode 277 of the Enormocast, we connect with the inimitable Kurt Smith. Kurt grew up in the 70s in Tahoe and through friendships with local climbers like Rick Lovelace and encounters with Yosemite Climber, Kurt found himself in Joshua Tree amongst the Stonemasters in the early 80s. Soon, Kurt and his crew were making … Continue reading "Enormo…

1
Cell Therapy For Corneal Endothelial Dystrophies With Aurion Biotech's Greg Kunst 13:41

7M ago13:41

13:41

We love to hear from our listeners. Send us a message. For this third and final episode recorded at ARM's 2023 Meeting on the Mesa, Cell & Gene: The Podcast Host, Erin Harris, sat down with Greg Kunst, president, CEO, and Board member at Aurion Biotech. Listen in as they discuss the cell therapy used to treat corneal endothelial disease and how Gre…

1
Enormocast Tweener: A Candid Ascent of Trango Tower with Jordan Cannon, Jesse Huey, and Matt Segal [Part 2] 57:12

7M ago57:12

57:12

When we left the boys in the last Episode, they had just summited the Trango Tower via the 2nd ascent of Cowboy Direct. In this installment, the summit emotions and revelations come fast and furious as well as the realization that hits every alpinist on the summit: “Oh, shit, we still gotta get off this … Continue reading "Enormocast Tweener: A Can…

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Enormocast 276: A Candid Ascent of Trango Tower with Jordan Cannon, Jesse Huey, and Matt Segal [Part 1] 1:46:33

7M ago1:46:33

1:46:33

On Episode 276 of the Enormocast, three guys dreamed big and got it done. Climbers Jordan Cannon and Jesse Huey hitched their wagons to Matt Segal‘s long standing dream of free climbing the second ascent of Todd Skinner et al’s master piece, Cowboy Direct, on Trango Tower in Pakistan (AKA Nameless Tower). What ensued was … Continue reading "Enormoc…

1
Overcoming the Limitations of CAR T-Cell Therapy with Vittoria Bio's Nick Siciliano, Ph.D. 17:23

8M ago17:23

17:23

We love to hear from our listeners. Send us a message. Vittoria Biotherapeutics’ CEO, Nick Siciliano, joins Erin Harris on this episode of Cell & Gene: The Podcast to discuss the company's mission to expand the applications for CAR-based therapeutics by employing novel cell engineering and gene editing technologies.…

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Enormocast 275: Anna Liina Laitinen – Born to Kiivetä 1:22:40

8M ago1:22:40

1:22:40

On Episode 275 of the Enormocast, I sit down face to face with Finnish climber Anna Laitenin. After a youth in gymnastics, Anna found climbing and then almost accidentally found herself one of the best climbers in Finland. A life of competitions and pursuing hard climbs at home and beyond followed, as did becoming a … Continue reading "Enormocast 2…

1
Gene Therapy Deals, Collaborations, & Partnerships with Astellas' Richard Wilson 25:02

8M ago25:02

25:02

We love to hear from our listeners. Send us a message. Richard Wilson, Senior Vice President, Primary Focus Lead, Genetic Regulation at Astellas sat down with Cell & Gene: The Podcast's Erin Harris at ARM's 2023 Meeting on the Mesa to discuss the gene therapy deal making landscape as well as Astellas' recent deals and collaborations. They also disc…

1
Enormocast 274: Roger Schaeli – In The Shadow of the Eiger 1:27:42

8M ago1:27:42

1:27:42

On Episode 274 of the Enormocast, I connect over the Atlantic with Swiss alpinist, guide, and Eiger North Face aficionado, Roger Schaeli. Roger was born directly in the Swiss alps and learned to climb at an early age with his father. Surrounded by deep Swiss climbing culture, an early accident did not deter Roger, rather … Continue reading "Enormoc…

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The Promise of AAV Gene Therapy with REGENXBIO's Ken Mills 28:34

8M ago28:34

28:34

We love to hear from our listeners. Send us a message. Ken Mills, CEO, President, and Director at REGENXBIO joins Erin Harris for this episode of Cell & Gene: The Podcast to discuss the company's progress with its Phase I/II Affinity Duchenne trial of RGX-202 for the treatment of Duchenne Muscular Dystrophy. They discuss the future of AAV gene ther…

1
Inside 2023 Meeting on the Mesa with ARM's COO, Rita Johnson-Greene 16:33

9M ago16:33

16:33

We love to hear from our listeners. Send us a message. Alliance for Regenerative Medicine's COO, Rita Johnson-Greene, joined Cell & Gene: The Podcast host, Erin Harris, in person at the 2023 Meeting on the Mesa to discuss this year's event. Johnson-Greene also shared what's ahead for 2024 as the event heads to a new location. They discussed major t…

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Enormocast 273: Brette Harrington – Keeper of the Flame 1:36:31

9M ago1:36:31

1:36:31

On Episode 273 of the Enormocast, I reconnect with Brette Harrington who appeared on the Enormocast in 2016. Just after that first appearance, Brette and Mayan Smith-Gobat left for an audacious attempt on free climbing Riders on the Storm on Torre Central on the Torres de Paine massif. Even though they failed in their ultimate … Continue reading "E…

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Enormocast 272: Connor Herson – Deeds of Youth 1:18:16

9M ago1:18:16

1:18:16

On Episode 272 of the Enormocast, I connect with young trad-phenom, Connor Herson. Connor first burst into climbing’s collective consciousness with the 6th free ascent of the Nose at the tender age of 15. Connor had already climbed 14 5.14s by the age of 14 (say that ten times fast), and he went on to … Continue reading "Enormocast 272: Connor Hers…

1
The Future of Cell and Organ Transplantation in Treating T1D with Dr. Camillo Ricordi 18:15

9M ago18:15

18:15

We love to hear from our listeners. Send us a message. A pioneer and an icon in diabetes research, Camillo Ricordi, M.D., is the Professor of Surgery, Director of Cell Transplant Center and Director Emeritus of the Diabetes Research Institute at the University of Miami Miller School of Medicine, Florida (UM-DRI). He joins Cell & Gene: The Podcast's…

1
In Vivo CAR T-Cell Therapeutics With Umoja Biopharma's Dr. Andrew Scharenberg 30:37

10M ago30:37

30:37

We love to hear from our listeners. Send us a message. Umoja Biopharma's CEO, Andy Scharenberg, M.D., joins Cell & Gene: The Podcast's Erin Harris to discuss the evolution of allogeneic, in vivo CAR-T cell therapeutics. They discuss The Climb, or The Colorado Laboratory and Innovation Manufacturing Building, which is Umoja’s lentiviral vector devel…

1
Enormocast 271: Charlie Schreiber – The Kids are Alright 1:21:23

10M ago1:21:23

1:21:23

On Episode 271, I am joined by climbing coach and former (maybe) competitor, Charlie Schreiber. Charlie coaches climbers of all ages, but the meat of this conversation is about youth climbing teams. Charlie has been a youth climbing coach since he was a youth himself. We discuss my own skepticism about the promise of youth … Continue reading "Enorm…

1
Inside Genome Editing with CBER's Dr. Peter Marks 25:17

10M ago25:17

25:17

We love to hear from our listeners. Send us a message. The FDA's Center for Biologics Evaluation and Research (CBER)'s Dr. Peter Marks makes his second appearance on Cell & Gene: The Podcast. This time Dr. Marks talks to Host, Erin Harris, about base editing and prime editing and their potential to meet unmet medical need. They discuss what clinica…

1
Enormocast 270: Briana Mazzolini-Blanchard – Doing What Needs to Be Done 1:33:48

10M ago1:33:48

1:33:48

On Episode 270 of the Enormocast, we are joined by Indigenous activist and climber, Briana Mazzolini-Blanchard. Though her path to accepting her heritage as a member of the CHamoru/Tugong Clan with origins in Guam was not without struggles, Briana has spent the last 6 years advocating for Indigenous peoples in Ohio and Eastern Kentucky. As … Contin…

1
Enormocast Tweener: Tyler Karow Saves a Goat (Maybe a Sheep?) 36:07

11M ago36:07

36:07

On this in-between episode of the Enormocast, you get the outtakes from Episode 269 with climber, Tyler Karow. After the official interview ended, we kept talking about climbing in Jordan, the social cost of the itinerant climbing lifestyle, and a few more tidbits for your pleasure. And the cops showed up. Enjoy this free “bonus” … Continue reading…

Podcasts Worth a Listen

Marcus Harrington Podcasts

Podcasts Worth a Listen

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