Dear listeners, This is a bittersweet moment for us. With this episode, we conclude the Personalized Medicine Podcast series. We would like to thank all of you for staying with us over the last 3 years! This has been an amazing ride and we appreciate your constant support and feedback. We hope you enjoyed listening to this show as much as we enjoye…

In this episode of the Personalized Medicine Podcast we sat down with Dr. Victor Bustos, the co-founder and COO of Refoxy Pharma, a pharmaceutical company focused on new therapies for age-related diseases. Victor is a molecular biologist by training and dedicated his research career to understanding the biology of aging. In this interview, we discu…

Welcome to the next episode of the Personalized Medicine Podcast. In this episode, our host Aradhana sat down for a conversation with Dr Ali Aghebat Rafat, Scientist at Tilibit Nanosystems. Aradhana and Ali discussed DNA nanostructures, DNA self-assembly, barcoding, biochips and their potential applications in Personalized Medicine. Tune in to this…

Welcome to the next episode of the Personalized Medicine Podcast. In this episode, our host Aradhana talked to Martin Rabel, the Field Application Scientist at Precision Nanosystems, about nanoparticles, microfluidics, gene delivery in the context of personalized medicine. Tune in to this episode to learn more about: ◦ Precision Nanosystems and the…

In this episode we dive deep into the world of structural biology. We discuss the role of cryogenic electron microscopy in the development of precision medicines with the founder and CEO of Gandeeva Therapeutics, Dr. Sriram Subramaniam. Cryo-EM opened a new way to study drug-target interactions and is changing the way we develop new therapies. Tune…

In this next podcast episode we dive into a topic of personalized skincare. Our host Oleksandr is joined by the co-founders of Mitra Bio, Dr. Shakiba Kaveh and Dr. Cristiana Banila. Pharmaceutical and personal care companies have been trying to unlock personalized skincare for decades. Shakiba and Cristiana bring a special key to the table, and it …

Welcome to the next episode of the Personalized Medicine Podcast. In this episode, we have talked about a variety of topics ranging from exploring space and microgravity for applications in biotechnology and physical science to developing pathogen detection systems. Our guest today is Dr. Daniela Bezdan, the Chief Scientific Officer of Yuri Gravity…

Welcome to the next episode of the Personalized Medicine Podcast. On this podcast we have talked extensively about antibody, vaccine and CAR-T cell based approaches to treat cancer. Today we will be talking about a new approach in oncology that is based on invariant Natural Killer T Cells, or iNKTs. Our guest today is Dr. Jennifer Buell, the founde…

In this episode we dive deep again into the topic of protein degradation and how it can be leveraged to treat neurodegenerative diseases. Our guest today is Dr. Beth Hoffman, the founder, CEO and President to Origami Therapeutics. Beth's career is a showcase of remarkable success in the biotech industry. She spent almost 25 years working in CNS dru…

Thank you very much for tuning into this special episode of the Personalized Medicine Podcast. Some of you might know that our founder and host Oleksandr (a.k.a. Sasha) is Ukrainian. In this difficult moment for his country, Sasha shares his thoughts on current situation in Ukraine and explains how anyone in the world can help and support people of…

In this episode we are returning to a very exciting topic of immunooncology and we will talk in detail about novel approaches to treat cancer, based on CAR-T cell technology. Please welcome Dr. Eric von Hofe, the Senior Advisor and former President of Affyimmune Therapeutics. Eric’s story is a showcase of a remarkable career in the biotech industry…

Welcome to the next episode of the Personalized Medicine Podcast. On this show we typically talk about science and technology driving the progress in personalized medicine. But the policy side of things and patient access are equally important. We are happy to welcome on our podcast Christopher Wells, the Vice President of Public Affairs at the Per…

Welcome to Season 3 of the Personalized Medicine Podcast! We hope you all head a good start in 2022 and are ready to dive deep into the world of personalized medicine with us again. In this first episode of Season 3, we address a very important and, frankly speaking, underappreciated topic of sepsis, commonly known as bacterial blood poisoning. Did…

Welcome to the final episode of 2021! This one was long in the making. We are happy to present the crossover episode between the Genetics Podcast and the Personalized Medicine Podcast. In this episode our host Oleksandr (Sasha) Yagensky wraps up 2021 with one and only Patrick Short, the CEO of Sano Genetics and host of the Genetics Podcast. Listen …

In this episode of the Personalized Medicine Podcast we are returning to the topic of aging. It is our pleasure to introduce to you the co-founder & CEO of Rejuvenate Bio, Daniel Oliver. Dan studied Mechanical Engineering & Business at Caltech and obtained an MBA from Harvard Business School. After completing his studies, Dan has co-founded several…

This is officially one of the most fun episodes of the Personalized Medicine Podcast. This time we sat down not just with one, but with two amazing guests. Please welcome the co-founders of Ochre Bio, Jack O’Meara and Quin Wills. Together we talked about livers, drug development for metabolic diseases and biotech entrepreneurship. This episode is f…

In this episode we are focusing on cancer, oncolytic viruses and how investor mindset helps building successful biotech companies. Our guest today is Arthur Kuan, the CEO of CG Oncology. Arthur is a molecular biologist by training. After completing his undergraduate training, Arthur started his career as a venture investor working at several promin…

In this episode of the Personalized Medicine Podcast we talk about precision oncology with a scientist and serial entrepreneur, Dr. Gang Song. Gang completed his PhD degree in Biochemistry and Molecular Biology at the Shanghai Medical College of Fudan University and then moved to Harvard where he did a PostDoc at the lab of Tim Springer where he wa…

On this episode we take a look at the role induced Pluripotent Stem Cells (iPSCs) are playing in drug discovery and development for neurodegenerative diseases. Our host Oleksandr sat down with Professor Evangelos Kiskinis, who is leading his own research group at the Northwestern University in Chicago. Evangelos and his team are leading the way on …

In this episode, we are diving deep into the world of the non-coding genome and, more specifically, an exciting new class of biomolecules - the long non-coding RNAs (lncRNA). Welcome, Dr. Samir Ounzain, the co-founder and CEO of HAYA Therapeutics. Samir and his startup HAYA are developing first-in-class therapies to target lncRNA responsible for th…

In this Podcast episode we return to the topic of stem cells. We discussed that autologous stem cells can be a powerful therapeutic tool for Parkinson’s disease in our interview with Professor Jeanne Loring. The challenge however is to manufacture those therapies at scale. Our guest on this episode is taking a major step in alleviating this hurdle.…

This Podcast episode cannot get any closer to what personalized medicine is really about. Welcome Dr. Dan Rhodes, the founder and CEO of Strata Oncology, a leading precision oncology company leveraging state-of-the art genomics tools for more efficient cancer diagnostics and treatment. Dan is a bioinformatician by training and spent his entire care…

In this episode, we return to our beloved field of proteomics. This time we focus on answering a question on how automation and AI can improve biomarker discovery and ultimately benefit patients. Our guest is Dr. Sophia Doll, co-founder of OmicEra Diagnostics, one of the most exciting startups in the field of proteomics today. Sophia did her Ph.D. …

In this episode we talk about multiple sclerosis (MS) and the role personalized medicine and real world data (RWD) are playing in treating this disease effectively. To discuss this topic, we sat down with one of the leading experts in this field - Dr. Rick Rudick. Rick is a neurologist by training and has more than 25 years of experience at Clevela…

Scientists today still spend an enormous amount of time on physical labor: pipetting, feeding cells, taking microscope images and performing all kinds of other experiments manually. That leaves researchers with a very limited time to do their core activities such as reading, talking to their colleagues and coming up with new hypotheses. Our guest o…

In this episode of the Personalized Medicine Podcast, we sat down with the guru of bioinformatics, Dr. John Castle. John is a physicist by training who found a passion for answering complex questions in drug development using a data-driven approach. He led bioinformatics teams at multiple successful companies including Rosetta Inpharmatics, Merck a…

In this episode, our host Aradhana Chopra sat down with Leo Martinez, one of the co-founders of Colorimetrix, the mobile health tech company behind the Pearl Fertility app. It is the first App to be approved as a medical device to monitor and chart all-important hormones of the menstrual cycle at home and help women with their fertility decisions. …

Welcome to the first episode of the Personalized Medicine Podcast in 2021. And what a guest do we have to kick-off this year! In this episode, we dive deep into the world of stem cells with one of the most influential scientists in the field, Professor Jeanne Loring. Jeanne is a Professor Emeritus and a Director of the Center for Regenerative Medic…

In Episode 3 of Season 2 of the Personalized Medicine Podcast, our new host, Aradhana Chopra, sat down with Dr. Cosimo Ducani. Cosimo is the founder and CEO of Moligo Technologies, a Biotech start-up from Sweden that aims at providing alternative and improved enzymatic nucleic acid synthesis methods at the industrial scale. Cosimo talks about the i…

The next episode of the Personalized Medicine Podcast is out! In this episode we take a look at the role of genetic factors in the development of neurological disorders. Our host Oleksandr Yagensky sat down with one of the gurus of the field, Prof. Naomi Wray. Naomi holds joint appointments at the Institute for Molecular Bioscience (IMB) and the Qu…

We are back! The first episode of Season 2 of the Personalized Medicine Podcast is out! In this episode, our host Oleksandr Yagensky sat down with Dr. Oliver Rinner, co-founder, and CEO of Biognosys, a proteomics technology company. We discussed the growing role of proteomics in healthcare, its impact on biomarker discovery, and the development of …

Welcome to the final episode of Season 1 of the Personalized Medicine Podcast! In this episode we look back at the past 9 months, share our own story and remember the most exciting moments of season 1. Our entire team has joined for the recording to share and discuss what we have learned from our guests. We have covered a broad range of topics span…

Precision medicine has the potential to transform healthcare in terms of diagnostics, treatment, and prevention of disease. But what does a future with a more personalized approach to medicine look like? Who will ultimately benefit from precision medicine? In this episode, we dive into these questions with Dr. Kadija Ferryman, a cultural anthropolo…

In episode 15, our host Oleksandr Yagensky sat down with Dr. Liz O’Day, the founder and CEO of Olaris, a biotech company that enables patients to pursue most effective personalized treatments. Liz unravels how small molecule metabolites along with machine learning can be utilized to evaluate patient-specific responses to therapeutics. Together with…

Recently glycans have been receiving a lot of attention. It turns out, the surface of coronavirus is packed with glycans, which help this virus evade our immune system. In this episode, we interviewed Dr. Parastoo Azadi, whose recent research sheds light on the structure of coronavirus core surface glycoprotein, and hence can facilitate the develop…

In thirteen episode of the Personalized Medicine Podcast we focus on the personalization of treatment in clinical practice. There is mourning evidence that shows that variations in the genome can significantly affect inter-patient differences in drug response. Together with Amani Saini, the founder of Adverse Drug Reaction (ADR) Canada, we talk abo…

In Episode 12, we discuss the progress of personalization in the field of reproductive medicine with our guest Dr. Helen O'Neill. Helen is a Lecturer in Reproductive and Molecular Genetics and Director for the MSc Program in Reproductive Science and Women’s Health at the Institute for Women’s Health, University College London. She has over 10 years…

In Episode 11 of the Personalized Medicine Podcast our host Oleksandr Yagensky discussed the topic of genetic data management with Dr. Mark Hahnel. Mark is the co-founder of Genomes.io, a personalized DNA databank that gives consumers ultimate control of their genome data. He is also CEO and founder of Figshare, repository for published and unpubli…

In the tenth episode of the Personalized Medicine Podcast, we talk about digital health technology in Rwanda. Our host Luisa Hallmaier-Wacker talks to Dr. Patrick Singa, the medical director babyl, about telehealth and the integration of AI into clinical diagnostics. Babylon Health, which is based in the UK, launched babyl in 2016 in Rwanda and est…

In episode 9 we dive deep into the topic that could not be more relevant today - diagnosis of infectious diseases. Our guest on this episode is Tim Blauwkamp, the co-founder and Chief Scientific Officer of Karius, a company that leverages genomics and AI to develop highly-accurate diagnostic tests based on cell-free DNA sequencing. Karius has recen…

In the eighth episode of the Personalized Medicine Podcast we discuss the role of AI in psychiatric treatments with Dr. Maryna Polyakova. Maryna is a medical doctor by training and a scientist who recieved her PhD from the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig. She is also the CEO and co-founder of AccuBio, a compan…

In episode 7 we are addressing a topic that is important in many areas of personalized medicine – data privacy protection, together with Dr. Rachele Hendricks-Sturrup. Rachele is a prominent academic in the field of consumer privacy and currently serves as a Health Policy Counsel at the Future of Privacy Forum. The Future of Privacy Forum is a nonp…

In episode 6 we are addressing one of the hottest topics in modern medicine – Immuno Oncology, together with Dr. Stefaan van Gool. Stefaan is a Medical Director of Translational Oncology at the Immunooncological Clinical Center in Cologne, Germany. IOZK is one of the most advanced institutions of this kind in the country. Stefaan has more than 25 y…

In the episode 5 we dive deep into the topic of digitalization in personalized healthcare. A lot has been going on in this space lately, especially in Germany. Therefore we are delighted to talk to one of the key opinion leaders on this topic, Professor David Matusiewicz. David is a professor of Healthcare Management at the FOM University for Appli…

On the fourth episode of the Personalized Medicine Podcast we switch gears from biomarker research to clinical trials with Christian Erb. Christian is a co-founder and CEO of Mondosano, a Hamburg-based company that addresses the bottleneck for a successful clinical trial – patient recruitment. Listen to our discussion with Christian to learn more a…

In the third episode of the Personalized Medicine Podcast we discuss glycans and their role in personalized medicine with Professor Gordan Lauc. Gordan is a Professor of Biochemistry and Molecular Biology at the University of Zagreb. He is also a Founder and CEO of Genos, one of the few companies in the world capable of high-throughput glycan analy…

In the second episode of the Personalized Medicine Podcast we dive into the world of genomics with Dr. Rocío Acuña Hidalgo. Rocío is a Chief Technology Officer at Nostos Genomics, a Berlin-based company that develops AI tools to diagnose patients with genetic diseases. Tune into this episode to learn more about: •The role of the Human Genome Projec…

In this episode we discuss the importance of protein biomarkers in clinical diagnostics with Professor Kevin Mills. Kevin is a head of Translational Mass Spectrometry Research Group at University College London and co-authored more than 150 publications in the field of biomarker research. His test for the diagnosis of Fabry disease is used today to…