Paul and Olivia are the premiere young sibling duo in conservative politics. Each week they break down the latest news out of Washington, the Trump administration, and across the country with a uniquely traditionalist and Catholic bent that is indebted to the broader Western tradition. They also regularly feature some of the most influential voices in politics, media, and academia. Come join us Tuesdays and Thursdays. Visit our website www.rightonpointpodcast.com to learn more!
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A myriad of AI, science, and technology experts explore the real challenges and enormous opportunities facing entrepreneurs who are building the future of health. Raising Health, a podcast by a16z Bio + Health and hosted by Kris Tatiossian and Olivia Webb, dives deep into the heart of biotechnology and healthcare innovation. Join veteran company builders, operators, and investors Vijay Pande, Julie Yoo, Vineeta Agarwala, and Jorge Conde, along with distinguished guests like Mark Cuban, Greg ...
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1
Harnessing Water Dynamics for Drug Design with Michael Crackower and Jason Burch
37:24
37:24
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Michael Crackower, PhD, Chief Scientific Officer of Ventus Therapeutics, and Jason Burch, PhD, join Vineeta Agarwala, MD, PhD, general partner at a16z Bio + Health. Together, they talk about how Ventus approaches drug discovery and why they believe we’re in the early stages of small molecule innovation. Specifically, we’ll hear about the ReSOLVE pl…
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AI at the Intersection of Bio with Vijay Pande, Surya Ganguli, and Bowen Liu
30:08
30:08
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30:08
Bowen Liu, PhD, investing partner, and Surya Ganguli, PhD, venture partner, join Vijay Pande, PhD, general partner of a16z Bio + Health. Together, they detail different methods through which AI could assist drug development, the opportunity for AI to flag new targets and compounds for scientists to investigate, and the science fiction-sounding noti…
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1
The History and Future of CAR T with Bruce Levine
31:26
31:26
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Bruce Levine, PhD, the Barbara and Edward Netter Professor in Cancer Gene Therapy at the University of Pennsylvania, joins Jorge Conde, general partner, and Ginger Liau, partner at a16z Bio + Health. Bruce talks about how his time working in a lab at the Children’s Hospital of Philadelphia inspired him to work on translational therapies. Together, …
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Implementation, Data, Impact of Healthcare AI with Vijay Pande and Julie Yoo
35:28
35:28
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In this episode, a follow-up to our episode Grand Challenges in Healthcare AI, Julie Yoo and Vijay Pande, a16z general partners, answer audience questions about AI applications in healthcare. Together, they dive into cost and implementation challenges, the data landscape, and what the patient experience might look like. If you liked this episode, l…
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1
Protecting the Golden Age of Medicine with John Crowley
30:33
30:33
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30:33
John Crowley, President and CEO of Biotechnology Innovation Organization (BIO), joined Jorge Conde, general partner at a16z Bio + Health. Together, they talk about John’s entry into biotech and his time as a founder, all motivated by his determination to discover and develop a treatment for his children, who have Pompe disease. They also talk about…
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A Fatal Inheritance with Lawrence Ingrassia
28:05
28:05
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28:05
Lawrence Ingrassia, author and journalist, joins Vineeta Agarwala, general partner, and Kris Tatiossian, editorial lead at a16z Bio + Health. Together, they discuss Larry's recently published book, A Fatal Inheritance: How A Family Misfortune Revealed A Deadly Medical Mystery. In the book, Larry recounts the story of the p53 cancer suppressor gene,…
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1
Network Medicine with Jonathan Swerdlin and Mark Hyman
33:14
33:14
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Jonathan Swerdlin, cofounder and CEO, and Mark Hyman, MD, cofounder and Chief Medical Officer of Function Health join Vijay Pande, general partner, and Daisy Wolf, investment partner of a16z Bio + Health. Together, they discuss their personal health journeys that led to founding Function, how they’re planning to scale Function, and what the future …
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1
Regulation as a Catalyst with Jonathan Bush and Chris Severn
37:08
37:08
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Jonathan Bush, founder and CEO of Zus Health, and Chris Severn, cofounder and CEO of Turquoise Health, join Julie Yoo, general partner, and Colin Rom, head of public policy for a16z Bio + Health. We’ve long believed that regulatory change can be a catalyst for company creation. In this episode, Jonathan and Chris detail how that was true for them. …
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1
The Transformative Power of AI in Science with Pushmeet Kohli
56:25
56:25
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In this episode, originally recorded for the a16z Podcast, host Steph Smith interviews Pushmeet Kohli, DeepMind's VP of Research focused on AI for science. They are joined by a16z Bio + Health founding partner Vijay Pande. Together, they discuss AI at scale, and its power to transform science.By Steph Smith, Pushmeet Kohli, Olivia Webb, Vijay Pande, Kris Tatiossian
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1
The Science and Supply of GLP-1s with Chronis Manolis
31:30
31:30
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Chronis Manolis, SVP and Chief Pharmacy Officer of UPMC Health Plan, joins Julie Yoo, general partner, Daisy Wolf, investment partner, and Will Shrank, venture partner, of a16z Bio + Health. Together, they discuss how payors and providers are thinking about anti-obesity medications, as well as pricing and prior authorization considerations. This is…
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The Science and Supply of GLP-1s with Brooke Boyarsky Pratt
42:53
42:53
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42:53
Brooke Boyarsky Pratt, founder and CEO of knownwell, joins Vineeta Agarwala, general partner at a16z Bio + Health. Together, they talk about the value of obesity medicine practitioners, patient-centric medical homes, and how Brooke believes the metabolic health space will evolve over time. This is the second episode in our series on the science and…
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The Science and Supply of GLP-1s with Carolyn Jasik
29:42
29:42
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Carolyn Jasik, MD, Chief Medical Officer of Omada Health, joins Vijay Pande, founding partner of a16z Bio + Health. As Ozempic, Wegovy, Mounjaro, and Zepbound capture the healthcare spotlight, we’ve developed a series of episodes that go beyond the headlines and take you into conversations with the specialists. Our first guest is Carolyn Jasik, Chi…
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The Intersection of Biotech x High Tech with Vineeta Agarwala
57:09
57:09
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Vineeta Agarwala, MD, PhD, joins Luke Timmerman's The Long Run podcast on stage at the Life Science Innovation Northwest Conference. They discuss everything from AI for drug discovery to Vineeta's ongoing clinical work as a physician and how that influences her perspective.By Luke Timmerman, Olivia Webb, Kris Tatiossian, Vineeta Agarwala
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AI in Pharmaceutical R&D with Kim Branson
31:15
31:15
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Kim Branson, PhD, SVP and Global Head of AI and Machine Learning for GSK, joins Vijay Pande, founding partner at a16z Bio + Health. Together, they talk about how AI has improved drug discovery and development, as Kim walks through all the ways AI can be deployed in the lab. They also get into detail about what an ideal partner looks like and what k…
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In this episode, Carl June, MD, pioneering immunologist and oncologist at the University of Pennsylvania, joins Jorge Conde, general partner at a16z Bio + Health. Together, they discuss Carl's work on CAR T, a remarkable story of the first use of CAR T in a pediatric patient, and Carl's take on where oncology treatments are headed next. Though this…
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1
Longevity as a Health Asset with Tom Hale
27:54
27:54
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Tom Hale, CEO of ŌURA, joins Vijay Pande, founding partner, and Daisy Wolf, investment partner at a16z Bio + Health. Together, they talk about the potential of wearables to change behavior, and how that can affect health. They also discuss how AI could maximize the usefulness of wearables and power the insights provided to wearers.…
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1
The Power of Drug Discovery with Philip Tagari
31:36
31:36
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31:36
Philip Tagari, Chief Scientific Officer of insitro, joins Vijay Pande, founding general partner at a16z Bio + Health. Together, they discuss the transformative power of drugs in changing human health—and history. They also reflect on the evolution of the drug discovery process as it shifts from serendipitous discovery to AI-enabled engineering. Fin…
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AI-Enabled Continuity of Care with Ed and Todd Park
25:41
25:41
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Vijay Pande, founding general partner of a16z Bio + Health, chats with the builders (and siblings) behind Devoted Health, Ed and Todd Park. The Park brothers, with decades of expertise in healthcare and policy, including as EVP and COO at athenahealth (Ed) and Chief Technology Officer of the United States (Todd), started Devoted with the idea of bu…
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Grand Challenges in Healthcare AI with Vijay Pande and Julie Yoo
38:33
38:33
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Vijay Pande, founding general partner, and Julie Yoo, general partner at a16z Bio + Health, come together to talk through the grand challenges facing healthcare AI today. The discussion covers the implications of AI integration in healthcare workflows, AI as a potential catalyst for value-based care, and the potential for innovation in clinical tri…
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Adapting Biopharma to AI with Greg Meyers
33:30
33:30
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Greg Meyers, EVP and Chief Digital and Technology Officer at Bristol Myers Squibb (or BMS), joins a16z Bio + Health general partner Jorge Conde. Together, they talk about how AI could transform drug discovery and development at a large biopharma company—and how a company might have to adapt to harness AI; modalities they’re excited about; and Greg’…
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1
Behind the Buy: Payors and Providers on AI Adoption
23:51
23:51
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As any healthcare founder knows, it can be difficult to get into a room with the executives making purchase decisions for payors and providers—so we’re bringing the executives to you. This episode features interviews with payor and provider leaders about what they’re seeing and how they’re thinking about AI. Guided by Julie Yoo, general partner, an…
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Biotech Revolution with Software Engineering Daily
54:12
54:12
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"There is a revolution unfolding in biotech. The confluence of new biological methods like CRISPR, virtually unlimited computational capacity, and machine learning has fundamentally transformed our ability to engineer biology for wide-ranging applications." Vijay Pande, founding general partner at a16z Bio + Health, joins the Software Engineering D…
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1
Dark Genome Hunting with Rosana Kapeller and Marty Taylor
38:18
38:18
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38:18
Rosana Kapeller, CEO of Rome Therapeutics, and Marty Taylor, physician-scientist at Harvard Medical School, join Vineeta Agarwala, general partner, and Bryan Faust, investment partner at a16z Bio + Health. Together, they discuss Rosana and Marty's recent publication regarding a virus-like element in our genome known as LINE-1. LINE-1, part of our "…
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Vijay Pande, founding partner of a16z Bio + Health, dives deep with a16z Podcast host Steph Smith into the potential of DNA as a data storage mechanism. This episode, a cross-post with the a16z Podcast, draws parallels between Moore's Law and the race for "Moore's Law for DNA." Vijay discusses the density, longevity, and ubiquity of DNA, and how th…
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The Most Interesting Healthcare Companies You've Never Heard Of with Julie Klapstein
28:20
28:20
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Julie Klapstein, founding CEO of Availity, long-time healthcare executive, and a16z Bio + Health's newest advisory partner, joins Julie Yoo, general partner at a16z Bio + Health. Together, they delve into Julie Klapstein's rich career journey, which has spanned several decades of progress in healthcare. They also discussed building Availity, her ti…
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Scribe Therapeutics cofounder and CEO Benjamin Oakes, PhD, joins a16z Bio + Health founding general partner Vijay Pande. In this episode, Benjamin traces his journey from PhD student to pioneering CEO in genome editing. Benjamin discusses his early exposure to CRISPR technologies, his hands-on experience of transforming these bacterial immune syste…
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1
Metrics for a Complex Machine with Josh Clemente
27:58
27:58
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Josh Clemente, cofounder and president of Levels, joins Vijay Pande, founding general partner, and Daisy Wolf, investment partner at a16z Bio + Health. In this episode, engineer-turned-entrepreneur Josh charts his journey from SpaceX and Hyperloop to cofounding metabolic health-focused company Levels. With a relentless drive for data-led health mon…
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Transitioning From Gymnast to Investor with Aly Raisman
27:24
27:24
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27:24
Former gymnast and current investor Aly Raisman joins general partner Julie Yoo and investment partner Daisy Wolf of a16z Bio + Health. In this episode, Aly Raisman shares her quest for healthier living—physically, mentally and financially—on her journey from gymnast to a business investor. Having herself transitioned from an intensely structured r…
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Finding PMF in Healthcare (After Tasting it Elsewhere) with Eren Bali and Max Cohen
32:56
32:56
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Max Cohen, cofounder and CEO of Sprinter Health, and Eren Bali, founder and CEO of Carbon Health, join Julie Yoo, general partner at a16z Bio + Health. Together, they talk about becoming healthcare entrepreneurs despite non-healthcare backgrounds and what they had to learn along the way. They also discuss finding product-market fit, how they track …
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IRA, AI Regulation, and the Future with Joe Grogan
30:52
30:52
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In this episode, Joe Grogan, a senior fellow at the Leonard D. Schaeffer Center for Health Policy and Economics and a former senior government official, joins Vijay Pande, founding partner of a16z Bio + Health to discuss all things regulation. Together, they dive into Joe’s experience working in the early days of the Covid pandemic, how he thinks a…
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Today's episode features the CEO of Tome Biosciences, Rahul Kakkar, alongside John Finn, CSO of Tome. They are joined by Jorge Conde, general partner at a16z Bio + Health. Together, the three of them discuss the technology underlying Tome's work, known as PASTE, a genome editing technique. They also dive deep into how this technology could be appli…
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Past, Present, and Future of AI with Vijay Pande
39:18
39:18
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Bio Eats World is now Raising Health! Vijay Pande, founding partner of Bio + Health, is joined by Daphne Koller, Andrew Ng, Aviv Regev, and Jakob Uszkoreit. Vijay leads us on a reflective journey through the monumental achievements in AI from the 1980s to today, with a focus on the progress in healthcare and life sciences. This episode is drawn fro…
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Bio Eats World is now Raising Health! On this first episode of Raising Health, Sean Duffy, cofounder and CEO of Omada Health, joins Vijay Pande, founding partner of Bio + Health. Sean and Vijay discuss the building and growth of Omada, from the early days to now. As the cofounder of one of the original digital health companies, Sean has unique insi…
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By Olivia Webb, Kris Tatiossian
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1
Generalist Medical AI with Pranav Rajpurkar
30:58
30:58
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Pranav Rajpurkar, PhD, joins Vijay Pande, founding partner of a16z Bio + Health. In this episode, Pranav and Vijay discuss a future with generalist medical AI. This is the idea of a medical AI that isn’t narrowly tailored to one specific task. As Pranav notes in the episode, the research and development process in medical AI development so far has …
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Jordi Mata-Fink, PhD, cofounder of Gate Bioscience, joins Vineeta Agarwala and Ben Portney of a16z Bio + Health. In this episode, Jordi discusses how he and his cofounders are working to commercialize a novel class of therapeutics, termed 'molecular gates.' His company, Gate, is working to exploit a previously uncharted avenue in cell biology—the s…
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1
How to Build an AI-Native Health Plan with Mario Schlosser
30:07
30:07
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30:07
Mario Schlosser, cofounder, former CEO, and current President of Technology at Oscar Health, joins Julie Yoo of Bio + Health. The conversation explores how AI advancements can revolutionize traditional healthcare models by enhancing efficiency, personalizing care journeys, and integrating real-time data insights. Mario also discusses "benefit-less"…
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Bridging AI, Ethics, and Consumer Trust with Miriam Vogel
27:30
27:30
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27:30
Miriam Vogel, President and CEO of EqualAI, cohost of the podcast In AI We Trust?, and Chair of the National AI Advisory Committee, joins Vijay Pande of Bio + Health. Miriam offers pragmatic insights for founders on ethical integration of AI. She also outlines concrete steps to build trustworthy AI. Finally, she discusses the regulatory landscape a…
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Clinical Copilots: Augmenting Human Care with Suchi Saria
27:33
27:33
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AI trailblazer Suchi Saria, in conversation with Vijay Pande, sheds light on the winding path that led her to launch Bayesian Health, a bold effort to infuse intelligence into clinical workflows. With infectious optimism, Suchi describes her vision to create "clinical copilots" that augment human capabilities and unburden care teams. Yet she acknow…
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Fei-Fei Li, PhD, Professor in the Computer Science Department at Stanford University, and Co-Director of Stanford’s Human-Centered AI Institute, joins Bio + Health founding partner Vijay Pande. In this candid conversation, Li unfolds her transformation from a young immigrant to an influential figure in AI. The conversation explores the birth of Ima…
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Supercharging Discovery with Evan Feinberg
29:07
29:07
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Evan Feinberg, PhD, founder and CEO at Genesis Therapeutics, joins Vijay Pande of Bio + Health. Together, they talk about how Evan’s work in the lab (ironically, Vijay's lab at Stanford!) translated to the creation of Genesis, which is tackling the problem of drug discovery through AI. They also discuss how the Genesis team is building specifically…
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1
Evolving Biotechnologies with Olga Troyanskaya
23:44
23:44
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Olga Troyanskaya, a professor in the department of computer science at Princeton and Deputy Director for Genomics at the Flatiron Institute's Center for Computational Biology, joins Vijay Pande, founding partner of a16z Bio + Health. Together, they talked about Olga's background and how she got involved in genomics, as well as how evolving biotechn…
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CMO vs. CPO with Peter Shalek and Reena Pande
28:49
28:49
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Peter Shalek, a Chief Product Officer, currently at Stellar Health and formerly at AbleTo, and Reena Pande, currently a strategic advisor and formerly the Chief Medical Officer of AbleTo, join Julie Yoo and Justin Larkin of a16z Bio + Health. As Julie mentions during the episode, there’s international relations, and then there’s CMO/CPO relations. …
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Interpretability and the AI "Clear Box" with Surya Ganguli
24:58
24:58
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Note that due to technical difficulties, the audio quality of this episode may vary. Surya Ganguli, PhD, an associate professor at Stanford University and a neural dynamics researcher, joins Vijay Pande of Bio + Health. Together, Surya and Vijay chatted about the interpretability of AI and how the AI black box could someday become a "clear box." Th…
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This episode is live from our recent AI Revolutionaries (AIR) conference. In this episode, Daphne Koller, founder and CEO at insitro and AI expert, chats with Vijay Pande of Bio + Health. You can check out the full conversation with video and transcript at https://a16z.com/digital-biology/.By Daphne Koller, Vijay Pande
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1
When Quantity Becomes Quality with Aviv Regev
29:41
29:41
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Today's episode features Aviv Regev, PhD, the Head and Executive VP of Genentech Research and Early Development, and founding co-chair of the Human Cell Atlas. She is joined by Vijay Pande of Bio + Health. Together, Aviv and Vijay talk about how Aviv's love of both abstractions and details led her to biology, how CRISPR really set the field into mo…
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1
Navigating the Future of AI with Andrew Ng
31:29
31:29
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Andrew Ng, PhD, a distinguished authority in the field of AI, is known for founding DeepLearning.AI and multiple other ventures. He also co-founded and led Google Brain and serves as an Adjunct Professor in Stanford University's Computer Science Department. In this episode, he is joined by Vijay Pande, founding partner of a16z Bio + Health. Andrew …
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Carl June, MD, an immunologist and oncologist at the University of Pennsylvania, joins Jorge Conde, general partner at a16z Bio + Health. Together, Carl and Jorge talked about Carl's pioneering work in CAR T therapy — including the terrifying moment where he thought he had accelerated one of his patient's deaths, how he started working in human imm…
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Becoming a Partnership Pioneer with Dan Nomura
20:46
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Dan Nomura is a distinguished professor at UC Berkeley and an Investigator at the Innovative Genomics Institute, specializing in Chemical Biology and Molecular Therapeutics. He serves as the Director of the Novartis-Berkeley Translational Chemical Biology Institute and founded Frontier Medicines and Vicinitas Therapeutics. He’s also a16z Bio+Health…
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Wartime and Peacetime: Being a Leader with Ben Horowitz
36:11
36:11
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In this exclusive conversation from the Bio + Health BUILD summit, founding partner Ben Horowitz sits down with general partner Jorge Conde. They discuss everything from the inspiration behind Ben’s book The Hard Thing About Hard Things, how the open Internet was secured, the difference between wartime and peacetime CEOs, scaling culture, and under…
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