This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows 'This Week in Virology' (TWiV) and 'This Week in Parasitism' (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.
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316: Food Addiction and the Gut Microbiome
56:23
56:23
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TWiM describes experiments to explore gut microbiota signatures of vulnerability to food addiction in mice and humans, and how a phage tail-like protein suppresses competitors in populations of bacteria of plants. Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Become a patron of TWiM. Links for this episode Gut microbi…
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315: How Pseudomonas Became A Global Pathogen
58:00
58:00
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58:00
TWiM explores evolution and host adaptation of Pseudomonas infections of plants, and the impact of COVID-19 on ESBL-producing E. coli on urinary tract and blood infections. Hosts: Vincent Racaniello and Michael Schmidt. Become a patron of TWiM. Links for this episode Evolution and host adaptation of Pseudomonas (Science) Type III secretion system, …
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314: Microbes Sculpt Our Planet and Manage Inflammation
52:57
52:57
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52:57
TWiM explores the deep-dwelling microbes that sculpt our planet, and the use of microbes in bioelectronics to manage inflammation. Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Become a patron of TWiM. Links for this episode Deep-dwelling microbes that sculpt our planet (NY Times) Living bioelectronics resolve inflamm…
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From ASM Microbe in Atlanta, Georgia, Arturo joins TWiM to reveal the threats that fungi pose to human health, including the notorious Candida auris and many more and how committed experts are researching ways to save us and our food supplies. Hosts: Michael Schmidt, Mark O. Martin Guest: Arturo Casadevall Watch this episode: https://youtu.be/nKJe5…
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312: Cry Havoc!, and Let Slip the Phages of Healing
53:14
53:14
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TWiM explains a new mechanism for preventing lysogeny through temperate phage-antibiotic synergy, and Salmonella expansion in the murine gut dependency on aspartate derived from reactive oxygen species-mediated microbiota lysis. Hosts: Michael Schmidt, Petra Levin and Michele Swanson. Become a patron of TWiM. Links for this episode Temperate phage-…
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311: Bacteria, beware of siderophore-antibiotic hybrids
43:45
43:45
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43:45
TWiM explores how climate change may be increasing our risks to infectious disease and then how the Odyssey literally comes alive in our microbial world but fear not, unlike the Trojans, the bacteria are fighting back and have developed resistance to this novel class of newly developed antimicrobials. Become a patron of TWiM. Links for this episode…
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310: Starvation vs Dehydration: Who Loses, Who Wins?
58:38
58:38
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TWiM explores the plasticity of the adult human small intestinal stoma microbiota, and survival and rapid resuscitation that permit limited productivity in desert microbial communities. Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Subscribe to TWiM (free) on Apple Podcasts, Spotify, Android, RSS, or by email. Become …
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Today on TWiM, a charcuterie invasion, and how that acid in your stomach may protect from the invading hordes of microbes. Hosts: Michael Schmidt, Petra Levin and Michele Swanson. Become a patron of TWiM. Links for this episode 2024 Salmonella outbreak linked to charcuterie meats Multitier regulation of the E. coli extreme acid stress response by C…
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TWiM reviews a case of E. faecium bacteremia treated with combination bacteriophage and antibiotic therapy, and how dopamine receptor D2 confers colonization resistance via microbial metabolites. Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Guest: Mark O. Martin Become a patron of TWiM. Links for this episode Matters…
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307: Attaching and Effacing on a Pedestal
50:07
50:07
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50:07
TWiM reviews a case of E. faecium bacteremia treated with combination bacteriophage and antibiotic therapy, and how dopamine receptor D2 confers colonization resistance via microbial metabolites. Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Subscribe to TWiM (free) on Apple Podcasts, Spotify, Android, RSS, or by emai…
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TWiM discusses the identification of natural products from reconstructed ancient bacterial genomes, and how plant mRNAs move into a fungal pathogen via extracellular vesicles to reduce infection. Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin. Become a patron of TWiM. Links for this episode Natural products from ancient bacterial genom…
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TWiM reviews the ongoing cholera outbreak in Africa, and research showing that gut complement induced by the microbiota blocks pathogens and spares commensal bacteria. Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Become a patron of TWiM. Links for this episode Cholera in Southern Africa (Africa CDC) Deadly cholera ou…
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TWiM reveals a new population in the blue cheese-making fungus Penicillium roqueforti and identification of a quorum-sensing autoinducer and siderophore in uropathogenic Escherichia coli. Subscribe to TWiM (free) on Apple Podcasts, Spotify, Google Podcasts, Android, RSS, or by email. Become a patron of TWiM. Links for this episode New blue cheese-m…
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303: Can Our Microbiome Break Our Hearts?
56:32
56:32
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56:32
TWiM reveals a database of genome sequences of thousands of Mycobaterium tuberculosis, allowing association with resistance phenotypes to 13 antibiotics, and microbe-derived uremic solutes that enhance thrombosis potential in the host. Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson. Become a patron of TWiM. Links for this episode M…
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302: Itching and Scratching and New Antibiotics
54:33
54:33
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TWiM describes the mechanism for the S. aureus itch and scratch induced skin damage, and discovery of a novel class of antibiotics that targets the lipopolysaccharide transporter. Become a patron of TWiM. Links: S. aureus drives itch and scratch behavior (Cell) Staph scratches its itch (Cell) A new class of antibiotics (Nature) A new type of antibi…
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A highly reduced TWiM team presents a study of the use of phage diversity in cell-free DNA to identify bacterial pathogens in human sepsis cases, and the evolution, persistence, and host adaptation of a gonococcal antimicrobial resistance plasmid that emerged in the pre-antibiotic era. Hosts: Vincent Racaniello and Petra Levin Become a patron of TW…
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On the occasion of TWiM’s 300th episode, we discuss how two college students found a new antibiotic in soil, Barbara Iglewski’s passing, and Elio returns for an appearance. Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Guest: Elio Schaechter Become a patron of TWiM. Links for this episode Barbara Iglewski dies Antimic…
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