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Investigating Innovative Cardiovascular Research at the Intersection of Academic Theory and Clinical Practice. Podcasts are also available on most podcast services including Apple, Google and Pocket Cast
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At Patient Pulse, we aim to improve understanding of difficult topics in cardiology and medicine. Easy enough for the layman, but detailed enough for someone who wants to know more about their condition or that of a loved one. Also available on Apple Podcasts, Google Podcasts and most other services. Subscribe to have new podcasts sent directly to your player.
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This is a volume of poetry by Harry Graham. Graham was known for his satirical poetry, and this volume is a great example of his art. In this volume, Graham charicatures several famous historical or legendary personages, and allows himself some reflections on the story of that person's life. - Summary by Carolin
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show series
 
Dr Nero and Dr Gibson discuss how to understand the information when looking at clinical trial data. Is it meaningful for a patient? Did the trail population match the patient's risks and medical problems? The also discuss the importance of Shared Decision Making and the use of Absolute Risk Reduction and Number Needed To Treat when interpreting th…
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Dr Gibson and Dr Nero discuss the oft maligned issue of medical statistics. Their discussion covers the pros and cons of traditional Cox proportional hazards regression models and Kaplan-Meier curves and newer techniques including win ratios. They then dip their toes into AI. A great overview by one of our leading clinical trialists.…
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Jeff Scott, CEO of Section 810 communication, interviews Dr. Nero on ways to improve cardiac health. The cover a wide range of topics, from diet and exercise to medical therapy and advanced testing. Some future research topics are also discussed. Section 810 Communications is a training and development company based in Greenwich, CT. The interview …
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This episode is a deep dive into Lipoprotein a with Dr Steven Nissen from the Cleveland Clinic. He and Dr Nero discuss the genetics of Lp(a), its pathophysiology, current treatment strategies and research into lowering Lp(a) levels. This is a fascinating conversation that also discusses the role of coronary inflammation in the work of Dr. Paul Ridk…
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Dr Steven Nissen from the Cleveland Clinic discuses with Dr. Thomas Nero the basic clinical approach to Lp(a) with need for routine testing and a few simple case studies. In the second (longer podcast) they take a deep deep dive into Lp(a) genetic, pathophysiology and the current research trials.By Thomas Nero MD FACC
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Dr Steven Nissen and Dr Thomas Nero discuss the importance of Lipoprotein a -aka Lp(a)- and its clinical importance as a special type of LDL cholesterol which dramatically increases your cardiovascular risk. They also covers why it important to get it tested at least once and what you can do to lower your risk of heart attack if you have it. If you…
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Dr Thomas Nero speaks with Dr Aaron Baggish about coronary artery disease in the endurance athlete (and non-athlete as well!) They discuss cardiovascular testing in Masters athletes including ETT, coronary calcium scoring and CT angiography as well as risk factor identification, inflammation, physical & emotional stress and ongoing research. Dr Bag…
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Dr Nero discusses coronary artery disease and exercise with Dr. Aaron Baggish. Dr Baggish was the founder of the Cardiovascular Performance Program at the Mass General Hospital and is one of the best known sports cardiologists in the world. They discuss the importance of exercise, coronary artery disease in the endurance athlete and current cardiov…
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Dr Mandrola discusses recent trail data with Dr. Thomas Nero including the results from Artesia, NOAH Afnet 6, Frail AF, Azalea and Oceanic-AF. They also discuss Left Atrial Appendage Occlusion and utility of wearable devices. Finally, a shout out to Dr. Andre Foy and his work on multi-morbidity and its role in clinical trial interpretation.…
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Dr. Thomas Nero speaks with Dr. Mathew Budoff about Coronary Calcium Scoring, CT Coronary Angiography and cardiovascular outcomes. The discussion goes beyond basic risk factor enhancement, highlighting its role to help evaluate disease progression, power future clinical trials and determine efficacy of therapy. Along the way, they discuss coronary …
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Dr Mathew Budoff discusses the importance of Coronary Artery Calcium Scoring and CT Coronary Angiography to prevent and treat heart disease with Dr. Thomas Nero. In addition they discuss new goals for treating cholesterol based on the CAC. If you enjoy this podcast you can also listen to a longer, in depth discussion on FUTURE PULSE CARDIOLOGY.…
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Dr. Thomas Nero discusses current therapy with Factor X inhibitors, the new research with Factor XI inhibition and specifically the enrolling Milvexian clinical trials with Dr. C Micahel Gibson. In addition they discuss, the addition of these medications along wiht anti-platelet therapy, Lp(a) and other interesting current and future research in ca…
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Dr. Thomas Nero speaks with Dr Peter Toth about the dramatic change occuring in diabtetes management and its effect on cardiovascular disease. Starting with the biochemestry of diabetes and its effects at the cellular level, the discussion goes on to speak about the role SGLT2 inhibitors and GLP1 receptor agonists play in DM management as well as t…
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Dr Peter Toth discusses with Dr. Thomas Nero the new classes of diabetes medications, SGLT2 inhibitors (eg Jardiance) and GLP1 receptor agonists (eg Ozempic and Munjaro.) These drugs have been in the news due to an impressive effect on weight reduction, but they also improve cardiovascular outcomes in diabetic and non-diabetic patients.…
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Dr. Thomas Nero speaks with Dr. Peter Toth about the complex biology of lipids and atherosclerosis. In this episode Dr Toth dives into LDL goals, therapies for attenuating non-LDL risk, vascular biology and the where are research studies lead us in choosing therapies.By Thomas Nero MD FACC
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Dr Paul Ridker discusses his paper on residual inflammatory risk that was recently published in the Lancet with Dr. Thomas Nero. He discusses the pathology of inflammation as part of atherosclerosis, utilization of hs-CRP in clinical trials and in daily practice as well as current therapeutic options and ongoing investigations.…
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Dr Sharonne Hayes of the May Clinic discusses SCAD with Dr. Thomas Nero. Initially focusing on the new treatment paradigms, their wide ranging discussion covers etiology, pathophysiology and potential future therapeutic options. Tis is the first of a two part podcast.By Thomas Nero MD FACC
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Dr Kebrina Bartley discuses Spontaneous Coronary Artery Dissection (SCAD) and Heart Disease in Women with Dr Sharonne Hayes, Professor of Medicine at the Mayo Clinic. Their wide ranging conversation discuses SCAD, the difference between SCAD and atherosclerotic heart disease and approaching the female patient who presents with chest pain. The also …
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Dr. Nero discusses evaluation of coronary artery disease and coronary inflammaiton with Dr. Cheerag Shirodaria from the University of Oxford. Dr. Shirodaria along with Prof. Charalambos Antonidies at Caristo Diagnostics have developed a ground breaking technology that allows us to evaluate not just the severity of a coronary artery lesion, but also…
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Dr. Nero discusses with ways to evaluate coronary artery disease with Dr. Cheerag Shirodaria from Oxford. Dr. Shirodaria and his team at Caristo Diagnostics have developed a ground breaking technology that allows us to evaluate not just the severity of a coronary artery lesion, but also how inflamed it is and how likely it is to cause a heart attac…
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Prof. Christine Coughlin of Wake Forest School of Law speaks with Dr. Thomas Nero on the FDA approval process, emergency use authorization, Right to Try Legislation and the implications for clinical research, diversity and health care equity. Prof. Coughlin holds positions in the College of Medicine as well as the Law school and in the Center for B…
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Dr. Kebrina Bartley discusses cholesterol management with Dr. Thomas Nero. They go over the important roll that statins play in coronary artery disease prevention especially in association with diet and exercise. The also discuss other options for lowering cholesterol and briefly discuss the approach to treating patients who feel that they may be h…
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If you REALLY want to understand what your doctor is telling you and how she came to the decisions that she did, then you have to know a little bit about medical statistics. In this episode, we will go over how we make a diagnosis with testing, how to measure benefit of a treatment in relative vs absolute risk reduction , and how to "judge" a study…
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At Patients First, we aim to improve understanding of difficult topics in cardiology and medicine in general. Easy enough for the layman, but detailed enough for someone who wants to know more about their condition or that of a loved one. This first episode introduces the topic of outcomes based research and evidence based medicine. It also discuss…
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Understanding cholesterol is an important part of understanding your risk of heart disease and stroke. Your total cholesterol is made up of LDL (The bad cholesterol), HDL (the good cholesterol) and Triglycerides (which are also bad). Since it is made up of both bad and good parts, total cholesterol can be misleading. In this episode we introduce, N…
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