Emergency Medicine Cases – Where the Experts Keep You in the Know. For show notes, quizzes, videos and more learning tools please visit emergencymedicinecases.com
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Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
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Living together in a group is a strategy many animals use to survive and thrive. And a big part of what makes that living situation successful is listening. In this episode, we explore the collaborative world of the naked mole-rat. Threshold is nonprofit, listener-supported, and independently produced. You can support Threshold by donating today . To stay connected, sign up for our newsletter . Operation frog sound! Send us your frog sounds for an upcoming episode. We want you to go out, listen for frogs and toads, and record them. Just find someone croaking, and hit record on your phone. It doesn’t matter if there’s background noise. It doesn’t even matter if you’re not sure whether or not you’re hearing an amphibian—if you think you are, we would love to get a recording from you. Please also say your name and where you are in the world, and then email the recording to us at outreach@thresholdpodcast.org…
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Behind the Breakthrough
We are once again bringing you inside UHN's Krembil Brain Institute – one of North America's largest and most innovative neurological centres – to meet the scientists and physicians advancing discovery, the patients who inspire us and the care teams who support them. This season, we're exploring some big new research in brain health, including: What young women need to know about preventing a stroke? Can loneliness re-wire your brain? And how you can reduce your chances of Alzheimer's. We'll also take you to the forefront of AI-powered brain science, dive into the link between genetics and reading disabilities and find out why getting a good night's sleep is crucial for brain health. There are a million amazing things to know about your complex brain – and we couldn't be more excited to explore them with you. Season 3 launches on March 19, with episodes every other Tuesday. Subscribe to Your Complex Brain so you don't miss a thing.…
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Behind the Breakthrough
1 Dr. Gelareh Zadeh’s pioneering research in brain tumours 1:05:10
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Play Later Play Later Lists Like LikedUHN’s Dr. Gelareh Zadeh sits down to talk about her pioneering research of meningiomas – or skull based tumors, and her discovery of the biology – or makeup – of these meningiomas. She also speaks to her amazing career journey, starting with her family's decision to escape their homeland in Iran following the Iranian Revolution, landing in Winnipeg on a cold Boxing Day in 1988. From their she tracks her successful professional trajectory, and rise as a medical leader - including her appointment as Chair of Neurosurgery at the University of Toronto in 2020 - the first woman ever in Canada to lead a university neurosurgical program.…
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Behind the Breakthrough
1 Dr. Howard Abrams champions innovative housing solution to help seniors age at home 45:42
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Play Later Play Later Lists Like LikedDr. Howard Abrams leads a team that is pioneering an innovative solution to the gap in housing for older adults, along with providing health supports so that they can age at home with dignity. It’s called NORC – short for Naturally Occurring Retirement Community. What is a NORC? Everything from a co-op to a condo to an apartment building where older people make up the majority of residents. “Most older Canadians want to age in place, they want to age at home…it's where they've lived most of their life, and they know how to do that best,” says Dr. Abrams. So he and a team at the UHN NORC Innovation Centre in Toronto are helping to organize a structure for providing the necessary supports that allow these hubs of older adults to age in place as opposed to moving into a residential home or long term care. In addition to identifying and organizing a building to become a NORC, the UHN NORC Innovation Centre supports can include helping residents get to doctors appointments, and providing medical expertise for managing everything from foot care to cardiac issues to high blood sugar due to diabetes. There are now three NORC Innovation Centre projects up and running in Toronto, with more in the works. Dr. Abrams explains that the project team is gathering evidence and data for publication that will lead to proof of concept for NORC’s. If successful the goal is to scale this innovative solution for older adults across Ontario and the country.…
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Behind the Breakthrough
1 Sleep disruption research by UHN’s Dr. Tatyana Mollayeva shows the impact on recovery from brain injury, cognitive reaction 51:07
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Play Later Play Later Lists Like LikedIn the latest episode of UHN podcast Behind the Breakthrough we feature KITE researcher Dr. Tatyana Mollayeva, who talks about her pioneering research on sleep disruption and its impact on patients with neurological disease and brain injury. Her research, for example, reveals a connection between a patient’s ability to recover from mild traumatic brain injury and sleep disruption, and, she’s been able identify risk factors such as adverse cognitive reactions and loss of reaction time in people with mild TBI who have sleep issues. Dr. Mollayeva also speaks to her role as an educator, and, advocacy work promoting sleep health awareness, including with the World Health Organization where she has pushed for the inclusion of sleep as integral to brain health. And Dr. Mollayeva reveals her inspiring journey to becoming an award winning research scientist, beginning at age 16 after graduating high school in her hometown of Novyi Rozdil , Ukraine when she left to study the sciences and earn a medical degree in Moscow. In the early 1990s, she fled the collapsing Soviet Union to Turkmenistan, where she met her husband. After stints in Wyoming and then back to Turkmenistan, Dr. Mollayeva and her family were accepted in 2003 to come to Canada under the Independent Immigrant Program. In her 2022 acceptance speech upon receiving a prestigious Canada Research Chair, Dr. Mollayeva paid homage to all immigrants who take the risk of leaving their homeland to seek new opportunity. “As an immigrant, this award is not just for me. It is for all immigrants who have a passion and take the often frightening step of changing their professional identity.”…
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Behind the Breakthrough
1 Hunting the origin cell of Head and Neck Squamous Carcinoma 39:35
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Play Later Play Later Lists Like LikedDr. Laurie Ailles is an award winning senior scientist at UHN's Princess Margaret Cancer Center whose pioneering research revealed the origins of head and neck squamous cell carcinoma. Her discovery is now paving the way towards more accurate and individualized prognoses that better inform potential treatments and improve outcomes for patients with the disease. Dr. Ailles’ also speaks to her career path as a successful medical science researcher, which traces back to her peripatetic childhood journey of living in several countries around the world as the daughter of a CIDA employee. She credits those experiences for shaping her outlook and contributing to her resilience as a researcher.…
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Behind the Breakthrough
1 Leveraging the human microbiome to be a therapeutic agent 51:53
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Play Later Play Later Lists Like LikedThe human microbiome consists of viruses, fungi, bacteria - even parasites and protozoa - that live on and in our bodies. And today the microbiome is having a ‘scientific moment’. Researchers are testing its uses to improve health, and, as a therapeutic agent to treat everything from bloodstream infection to the ill effects of cancer treatment. In this episode of UHN's ‘Behind the Breakthrough’ leading Canadian microbiome research scientist Dr. Bryan Coburn explains how our understanding of the microbiome is growing exponentially, and the human clinical trials he’s conducting to determine if it can be a therapeutic tool to treat patients.…
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Behind the Breakthrough
1 UHN’s Dr. Cristina Nostro pioneers stem cell research to cure Diabetes 39:05
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Play Later Play Later Lists Like LikedIn this episode, we interview Dr. Cristina Nostro, a Senior Scientist at the McEwen Stem Cell Institute at UHN, on her developments in curing type one diabetes through the use of stem cells. She dives into the uptake of islet transplantation as a treatment option, along with the different methods and technological advancements to improve the life of people living with this autoimmune disease.…
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Behind the Breakthrough
1 Identifying novel acute pain treatments following major surgery 41:28
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Play Later Play Later Lists Like LikedThe podcast "Behind the Breakthrough" features Dr. Hance Clarke, an anesthesiologist and director of pain services at Toronto's University Health Network, discussing the challenges of managing pain after surgery. Dive into the consequences of the lack of a protocol and the scope and scale of addiction in Canada as a result of post-surgery pain. Dr. Clarke discusses the need for a balance between patient comfort and preventing addiction, and how his research protocols are used to achieve this balance. The opioid crisis has led to a focus on pain as a part of the process, and how to support patients through the hospital system…
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Behind the Breakthrough
1 Pioneering UHN research targets long-term complications of liver transplantation 46:50
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Play Later Play Later Lists Like LikedOn this episode of Behind the Breakthrough, Dr. Mamatha Bhat shares how she and her team of UHN researchers are leveraging artificial intelligence to help predict complications resulting in long-term outcomes for liver transplant patients. This novel, world-first approach has the ability to determine the personalized predictors of outcome for each patient – for example, increased risk of cancer, heart disease, and cardiovascular events are examples of what compromise long-term survival following transplantation, especially after the one year mark. This precision medicine approach can help identify which patients are at risk of which complications to help simulate diagnostic and therapeutic responses from a clinical practice perspective. Dr. Bhat speaks to the journey involved throughout the research process, as well as how she encourages future clinician-scientists to foster resiliency while engaging in their work as well as being opportunistic and creative.…
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Behind the Breakthrough
1 Dr. Andrew Boozary prescribes housing to curb homelessness 57:53
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Play Later Play Later Lists Like LikedSeason 5 launches with an interview with pioneering social medicine advocate Dr. Boozary, who speaks to how UHN is tackling one of the biggest challenges to health for those who are marginalized – homelessness. Dr. Boozary and UHN helped create an ambitious hospital-first in Canada – the construction of a supportive housing site in Parkdale, Toronto. In this wide-ranging and thoughtful interview Dr. Boozary makes the wider case that hospitals must expand their mission and lead innovations in a collaborative way to address the root causes of health problems. And he speaks to the immigrant journey of his Iranian-born parents and how their sacrifice to give him and his sister new opportunities in life shapes the work he does today.…
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Behind the Breakthrough
Season 5 is just around the corner, coming Fall 2023. Until then check-out our friends at UHN's Krembil Brain Institute as they launch season two of Your Complex Brain! Well, it’s no surprise. Since last season, our brains haven’t gotten any less complex! But that just means there are even more stories to share about the mysteries, myths and science behind how our brains work, and what keeps our brains healthy and fit. On Season 2 of our podcast Your Complex Brain, we’ll highlight the latest research, technology and innovations in brain science by speaking with thought leaders & experts, as well as patients, their families and the dedicated care teams on the front lines of keeping our brains healthy - and fixing them when illnesses arise. This season, we’ll be looking for answers to some pretty big questions – such as, ‘Is stress contagious?’ ‘Why are many women living with brain disease experiencing a delay in diagnosis?’ And, ‘How could advances in technology improve outcomes for patients who undergo deep brain stimulation?’ And those are just the first three episodes! There are a million amazing things to know about your complex brain – and we couldn’t be more excited to explore them with you.…
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Behind the Breakthrough
1 Dr. Shaf Keshavjee has transformed lung transplant worldwide with his medical discoveries 55:14
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Play Later Play Later Lists Like LikedRenowned UHN surgeon scientist Dr Shaf Keshavjee sits down with Behind the Breakthrough podcast Host Christian Cote’ and takes listeners on a behind-the-scenes journey of his ground breaking medical discoveries – two of which have had a profound impact on lung transplant around the world. For his Master’s thesis in the late 1980’s he developed a lung preservation solution – LDP – which is now the standard for lung preservation worldwide. Twenty years later he followed that up with the invention of a lung perfusion machine that preserves and treats damaged donor lungs outside the body – or ex vivo. The Toronto Ex Vivo Lung Perfusion System has doubled the number of lungs available for transplant and is now in use around the world. Today the system is being tested to treat other damaged organs including the liver, kidney, and heart. In this wide-ranging and revealing conversation Sprott Department of Surgery’s Dr. Keshavjee speaks to the importance of mentorship, the qualities necessary to be a successful scientist, and, the importance of scientists learning about patenting and commercializing their work.…
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Behind the Breakthrough
1 Pioneering the use of virtual reality devices to restore vision 41:09
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Play Later Play Later Lists Like LikedRestoring vision for the visually impaired has been a dream of scientists and clinicians for centuries. Neurodegenerative eye diseases like glaucoma or age-related macular degeneration affect visual information processing. But the visual system in humans is smart–it can compensate for a loss in connectivity caused by disease. The potential for virtual reality cognitive retraining may improve the quality of life in visually impaired individuals. These retraining devices are effortlessly portable; therefore, protocols can be completed from the comfort of someone’s home.…
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Behind the Breakthrough
1 Dr. Rama Khokha on her breakthrough to map the biology of pancreatic cancer 34:50
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Play Later Play Later Lists Like LikedPancreatic cancer is an aggressive disease with poor survival rates. Huge contributors to this dire outcome are the fact it is typically diagnosed at an advanced stage, has limited treatments, and no cure. This is what makes the discovery of Dr. Rama Khokha and her lab so profound. In this episode of Behind the Breakthrough podcast the senior scientist at UHN's Princess Margaret Cancer Centre walks us through her world first discovery - mapping the biology of a pancreatic cancer tumor. Dr. Khokha found three distinct tumor microenvironments [TME’s] for pancreatic cancer – Resistant; Deserted; and Intermediate. The Resistant TME was found to be the most aggressive, while the Deserted MTE was found to resist - and grow - during chemotherapy. Dr. Khokha’s mapping discovery now gives researchers a clear understanding of the behavior of pancreatic cancer. It has the potential of far reaching impact – contributing to research for new and improved treatments, the potential for earlier diagnosis, as well applying her mapping technique to other cancers such as colorectal and lung cancer.…
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Behind the Breakthrough
1 Promising new treatment for Parkinson’s Disease 41:54
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Play Later Play Later Lists Like LikedDr. Lorraine Kalia’s research looks at testing different compounds in C. Elegans and how it can lead to a better understanding of Parkinson’s disease and new therapeutic targets. The best part: some of these compounds are already approved for use in humans. Through Dr. Kalia’s research we may be able to repurpose these compounds for the neurodegenerative condition.…
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Similar to Behind the Breakthrough
Emergency Medicine Cases – Where the Experts Keep You in the Know. For show notes, quizzes, videos and more learning tools please visit emergencymedicinecases.com
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continue reading
Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
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continue reading
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continue reading
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continue reading
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continue reading
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There are a lot of fads, blogs and strong opinions, but then there’s SCIENCE. Science Vs is the show from Gimlet that finds out what’s fact, what’s not, and what’s somewhere in between. We do the hard work of sifting through all the science so you don't have to and cover everything from 5G and Pandemics, to Vaping and Fasting Diets.
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…
continue reading
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