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Humane intervention points, virtual gene knockout and ex vivo brain slices for Parkinson's research

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Manage episode 331765724 series 1466422
Content provided by LabAnimal, The NC3Rs, The North American 3Rs Collaborative, and Lab Animal. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by LabAnimal, The NC3Rs, The North American 3Rs Collaborative, and Lab Animal or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

June 2022


The papers behind the pod:

  1. Williams WO and Baneux P (2022). Humane Intervention Points: Refining endpoint terminology to incorporate non-euthanasia intervention options to improve animal welfare and preserve experimental outcomes. Laboratory Animals, in press. https://doi.org/10.1177/00236772221090801
  2. Osorio D et al. (2022). scTenifoldKnk: An efficient virtual knockout tool for gene function predictions via single-cell gene regulatory network perturbation. Patterns 3(3): e100434. https://doi.org/10.1016/j.patter.2022.100434
  3. Moudio S et al. (2022). Exposure of α-Synuclein Aggregates to Organotypic Slice Cultures Recapitulates Key Molecular Features of Parkinson's Disease. Frontiers in Neurology 13: e826102. https://doi.org/10.3389/fneur.2022.826102

It’s the third Thursday of June, and you’re listening to 3 Minute 3Rs, your monthly recap of efforts to replace, reduce and refine the use of animals in research. Follow this link for the full transcript:

https://nc3rs.org.uk/3-minute-3rs-podcast-june-2022-transcript



Hosted on Acast. See acast.com/privacy for more information.

  continue reading

64 episodes

Artwork
iconShare
 
Manage episode 331765724 series 1466422
Content provided by LabAnimal, The NC3Rs, The North American 3Rs Collaborative, and Lab Animal. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by LabAnimal, The NC3Rs, The North American 3Rs Collaborative, and Lab Animal or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

June 2022


The papers behind the pod:

  1. Williams WO and Baneux P (2022). Humane Intervention Points: Refining endpoint terminology to incorporate non-euthanasia intervention options to improve animal welfare and preserve experimental outcomes. Laboratory Animals, in press. https://doi.org/10.1177/00236772221090801
  2. Osorio D et al. (2022). scTenifoldKnk: An efficient virtual knockout tool for gene function predictions via single-cell gene regulatory network perturbation. Patterns 3(3): e100434. https://doi.org/10.1016/j.patter.2022.100434
  3. Moudio S et al. (2022). Exposure of α-Synuclein Aggregates to Organotypic Slice Cultures Recapitulates Key Molecular Features of Parkinson's Disease. Frontiers in Neurology 13: e826102. https://doi.org/10.3389/fneur.2022.826102

It’s the third Thursday of June, and you’re listening to 3 Minute 3Rs, your monthly recap of efforts to replace, reduce and refine the use of animals in research. Follow this link for the full transcript:

https://nc3rs.org.uk/3-minute-3rs-podcast-june-2022-transcript



Hosted on Acast. See acast.com/privacy for more information.

  continue reading

64 episodes

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