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Episode 1 - Crafting a Clot | Coagulation Cascade Overview
Manage episode 437451587 series 3596833
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Surely it's just clot or no clot right? Join your intrepid guides Nick, Cale and Bashar as we help you master the med school coagulation cascade and its relevance (or lack of) to laboratory testing of haemostasis.
Wait what’s that? Everything you’ve been taught so far is an irrelevant lie? Bring yourself up to speed with the cellular model of coagulation and learn what really happens to make that clot appear
Timestamps
00:00 - Introduction to Bloody Minded Podcast
02:57 - Episode Introduction
03:40 - What's the point?
04:35 - The coagulation cascade
07:00 - Common pathway
13:25 - Factor 13
14:10 - Extrinsic pathway
18:39 - Intrinsic pathway
23:58 - Why the classical model is broken
26:08 - Cellular model of coagulation
30:22 - Summary
Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
Chapters
1. Introduction to Bloody Minded (00:00:00)
2. Episode Introduction (00:02:57)
3. What's the Point? (00:03:40)
4. Coagulation Cascade (00:04:35)
5. Common Pathway (00:06:59)
6. Factor XIII (00:13:24)
7. Extrinsic Pathway (00:14:10)
8. Intrinsic Pathway (00:18:39)
9. Why the Classical Model is Broken (00:23:58)
10. Cellular Model (00:26:08)
11. Summary (00:30:22)
16 episodes
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