Rethinking catalysis

Bringing Chemistry to Life

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Modern synthetic chemistry relies on a rich toolbox of chemical transformations, among which catalytic reactions play a prominent role. Yet, despite all the many successes, innovation in the field has seemingly slowed down, the focus moving to exploring variations and application scope of well-established catalysts based on a limited number of reliable transition metals.

Josep Cornella, from the Max Planck Institute in Mülheim an der Ruhr, is an innovator. He is not loyal to a specific element or a specific catalyzed reaction. He has a non-discriminatory approach to catalysis, where the key is choosing the catalytic approach to do what he wants/needs rather than figuring out what he can do with his catalyst of choice.

This episode is a declaration of love for catalysis as a driver for innovation in organic synthesis. Paolo and Josep discuss using the elements the Earth has given us in creative new ways, from making air-stable nickel zero (Ni(0)) complexes to the unexpected use of bismuth as a completely novel catalyst, opening the box of possibilities by removing the biases from overreliance on well established – and old – concepts.

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About Your Host

Born and raised in Italy, Paolo Braiuca, a PhD in pharmaceutical sciences, co-founded a startup company after conducting research in biocatalysis in Italy and the UK. He transitioned from R&D to business development, working in commercial, product management, and marketing roles in the specialty chemicals, biotechnology, and pharmaceutical markets in Germany and the UK. A busy father of four, if asked, he’ll call himself a “maker” at heart and enjoys inventing electronic devices in his free time.