Sickle Cell's Cure: CRISPR

CEimpact Podcast

Sickle cell disease (SCD) is a devastating medical condition causing pain, fatigue, and early mortality. Join host, Geoff Wall, as he evaluates a new gene therapy via CRISPR that may cure SCD.
The GameChanger
CRISPR is a new method to develop targeted gene editing treatments. Lovo-cel is the first FDA-approved therapy and may treat sickle cell disease (SCD) - for only $2 million.
Host
Geoff Wall, PharmD, BCPS, FCCP, BCGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health
Reference
FDA Approval. https://www.fda.gov/vaccines-blood-biologics/lyfgenia.
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CPE Information

Learning Objectives
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Discuss what CRISPR is and how it can be used to treat diseases
2. Describe the use of lovotibeglogene autotemcel (lovo-cel) for sickle cell disease and its safety and efficacy data
0.05 CEU/0.5 Hr
UAN: 0107-0000-24-031-H01-P
Initial release date: 1/8/2024
Expiration date: 1/8/2025
Additional CPE details can be found here.

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Chapters

1. Sickle Cell's Cure: CRISPR (00:00:00)

2. New Treatments for Sickle Cell Disease (00:00:08)

3. CRISPR for Sickle Cell Disease Treatment (00:07:40)

4. Advances in Sickle Cell Disease Treatment (00:19:19)