PT Inquest is an online journal club. Hosted by Jason Tuori, Megan Graham, and Chris Juneau, the show looks at an article every week and discusses how it applies to current physical therapy practice.
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Content provided by Sean P. Kane, PharmD, BCPS, Sean P. Kane, and PharmD; Khyati Patel. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sean P. Kane, PharmD, BCPS, Sean P. Kane, and PharmD; Khyati Patel or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
Similar to HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast
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153 - Buy One Get One Free: Learning All about the Dual Acting GIP and GLP-1 Receptor Agonist
Manage episode 340305507 series 70056
Content provided by Sean P. Kane, PharmD, BCPS, Sean P. Kane, and PharmD; Khyati Patel. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sean P. Kane, PharmD, BCPS, Sean P. Kane, and PharmD; Khyati Patel or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
In this episode, we will discuss mechanism, pharmacokinetics, efficacy, safety, and possible place in therapy for tirzepatide (Mounjaro), a new treatment for type 2 diabetes.
Key Concepts
- Tirzepatide is a novel GIP and GLP-1 receptor agonist resulting in glucose-dependent secretion of insulin and a decrease in glucagon secretion.
- This medication was FDA approved in May 2022 for the treatment of type 2 diabetes as an adjunct to diet and exercise. It is available as a long-acting once weekly pen injection to be administered subcutaneously.
- Current efficacy data exist from a 40-week trial which showed that tirzepatide was superior to semaglutide in A1c reduction and weight loss.
- The most common adverse effects of tirzepatide include GI concerns such as nausea, vomiting, and diarrhea as well as hypoglycemia.
References
- Frias JP, Davies MJ, Rosenstock J, et al. Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes. N Engl J Med. 2021;385:503-515. https://www.nejm.org/doi/full/10.1056/NEJMoa2107519
- Mounjaro. Package insert. Elli Lilly and Company. 2022.
197 episodes
153 - Buy One Get One Free: Learning All about the Dual Acting GIP and GLP-1 Receptor Agonist
HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast
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Manage episode 340305507 series 70056
Content provided by Sean P. Kane, PharmD, BCPS, Sean P. Kane, and PharmD; Khyati Patel. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sean P. Kane, PharmD, BCPS, Sean P. Kane, and PharmD; Khyati Patel or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
In this episode, we will discuss mechanism, pharmacokinetics, efficacy, safety, and possible place in therapy for tirzepatide (Mounjaro), a new treatment for type 2 diabetes.
Key Concepts
- Tirzepatide is a novel GIP and GLP-1 receptor agonist resulting in glucose-dependent secretion of insulin and a decrease in glucagon secretion.
- This medication was FDA approved in May 2022 for the treatment of type 2 diabetes as an adjunct to diet and exercise. It is available as a long-acting once weekly pen injection to be administered subcutaneously.
- Current efficacy data exist from a 40-week trial which showed that tirzepatide was superior to semaglutide in A1c reduction and weight loss.
- The most common adverse effects of tirzepatide include GI concerns such as nausea, vomiting, and diarrhea as well as hypoglycemia.
References
- Frias JP, Davies MJ, Rosenstock J, et al. Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes. N Engl J Med. 2021;385:503-515. https://www.nejm.org/doi/full/10.1056/NEJMoa2107519
- Mounjaro. Package insert. Elli Lilly and Company. 2022.
197 episodes
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Similar to HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast
PT Inquest is an online journal club. Hosted by Jason Tuori, Megan Graham, and Chris Juneau, the show looks at an article every week and discusses how it applies to current physical therapy practice.
…
continue reading
Concise summaries of everything published in the latest weekly issue of the New England Journal of Medicine (NEJM). NEJM publishes new medical research findings, review articles, and editorial opinion on topics of importance to biomedical science and clinical practice.
…
continue reading
Emergency Medicine Cases – Where the Experts Keep You in the Know. For show notes, quizzes, videos and more learning tools please visit emergencymedicinecases.com
…
continue reading
Dr. Drew Pinsky, board certified internist and addiction medicine specialist, takes listener calls and talks to experts on a variety of topics relating to health, relationships, sex and drug addiction.
…
continue reading
Interviews with mathematics education researchers about recent studies. Hosted by Samuel Otten, University of Missouri. www.mathedpodcast.com Produced by Fibre Studios
…
continue reading
Seeking a healthier emotional life? It’s time to bring a trained psychologist and mental health expert along for the ride. Dr. Monica Johnson explains the why behind complex emotions, helps you form better relationships, and guides you down the path of self-understanding.
…
continue reading
A science guy from the deep south (Destin) and a humanities guy from the wild west (Matt Whitman) discuss deep questions with varying levels of maturity.
…
continue reading
From the stuff your mother never told you, to the stuff your doctor never learned, On Health features taboo-busting conversations that demystify and de-stigmatize our bodies, all while bridging the gap between conventional medicine and wellness. Join Yale-trained MD & midwife Aviva Romm and her line-up of expert guests as they discuss everything from periods to menopause, sex to reproductive health politics, and motherhood to mental health. Each week, Dr. Romm will be exploring the science a ...
…
continue reading
What Drives You, with over 70 million downloads and 1,350 episodes, gets to the root causes of personal transformation. Join elite athlete, personal development guide, serial entrepreneur, author, and father of nine Kevin Miller as he conducts deep dives with our world's greatest transformational luminaries to gain clarity on what we want and our motives for wanting it. This brings us into alignment so we can drive further and faster with less effort, and most importantly, enjoy the ride on ...
…
continue reading
True Crime Brewery is the true crime podcast that brings you deeply inside of a crime and its investigation. Hosts Jill and her pediatrician husband Dick use their medical knowledge and life experiences to share the stories behind some of the most compelling crimes from all over the world. And, just for fun, Dick uses his secondary expertise as a craft beer lover to review the best beers from the regions where each crime occurred. Meet this true crime obsessed couple at the quiet end of the ...
…
continue reading
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