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Using Antisense to Characterize Nonsense: A Mouse Model of Progranulin-Deficient Dementia

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Manage episode 402804775 series 3391756
Content provided by Bitesize Bio. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Bitesize Bio or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Transgenic mouse models are important tools for testing therapeutic strategies. In this episode of Listen In, discover the benefits and essential considerations when characterizing and using transgenic mouse models to test therapeutic approaches to treat neurodegenerative diseases.

Plus, explore a knock-in mouse model of frontotemporal dementia that harbors a common mutation in the progranulin gene to test an antisense oligonucleotide (ASO)-based therapeutic strategy.

Watch the full presentation here: https://events.bitesizebio.com/using-antisense-to-characterize/join

Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

  continue reading

113 episodes

Artwork
iconShare
 
Manage episode 402804775 series 3391756
Content provided by Bitesize Bio. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Bitesize Bio or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Transgenic mouse models are important tools for testing therapeutic strategies. In this episode of Listen In, discover the benefits and essential considerations when characterizing and using transgenic mouse models to test therapeutic approaches to treat neurodegenerative diseases.

Plus, explore a knock-in mouse model of frontotemporal dementia that harbors a common mutation in the progranulin gene to test an antisense oligonucleotide (ASO)-based therapeutic strategy.

Watch the full presentation here: https://events.bitesizebio.com/using-antisense-to-characterize/join

Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

  continue reading

113 episodes

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