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Visualizing Membrane Dynamics by Electron Microscopy

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Manage episode 401812512 series 3391756
Content provided by Bitesize Bio. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Bitesize Bio or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Explore how the latest electron microscopy techniques and volume imaging can capture fast, dynamic membrane and vesicle remodeling events during synaptic transmission at the ultrastructural level.

Neurons communicate at specialized junctions, or synapses, via chemical messengers called neurotransmitters. Within a millisecond of neuronal stimulation, synaptic vesicles packed with neurotransmitters fuse with the presynaptic plasma membrane and release their contents. These neurotransmitters then bind and activate receptors on the postsynaptic membrane, resulting in cell-to-cell signal transmission. Then, to sustain this neurotransmission, new vesicles are recruited to the release sites.

In this episode of Listen In, we dive into the powerful new technology to spatially and temporally investigate these dynamics.

Watch the full presentation here: https://events.bitesizebio.com/visualizing-membrane-dynamics-by/join

Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

  continue reading

122 episodes

Artwork
iconShare
 
Manage episode 401812512 series 3391756
Content provided by Bitesize Bio. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Bitesize Bio or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.

Explore how the latest electron microscopy techniques and volume imaging can capture fast, dynamic membrane and vesicle remodeling events during synaptic transmission at the ultrastructural level.

Neurons communicate at specialized junctions, or synapses, via chemical messengers called neurotransmitters. Within a millisecond of neuronal stimulation, synaptic vesicles packed with neurotransmitters fuse with the presynaptic plasma membrane and release their contents. These neurotransmitters then bind and activate receptors on the postsynaptic membrane, resulting in cell-to-cell signal transmission. Then, to sustain this neurotransmission, new vesicles are recruited to the release sites.

In this episode of Listen In, we dive into the powerful new technology to spatially and temporally investigate these dynamics.

Watch the full presentation here: https://events.bitesizebio.com/visualizing-membrane-dynamics-by/join

Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

  continue reading

122 episodes

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