All you need is LOVE

Science Savvy

38:05

In late 1972, U.S. Marine Captain Ron Forrester disappeared on a bombing run into North Vietnam. Back home in Texas, his family could only wait and hope. Audio subscribers to Texas Monthly can get early access to episodes of the series, plus exclusive interviews and audio. Visit texasmonthly.com/audio to join. Go to HelloFresh.com/FLIGHT10FM to get 10 Free Meals with a Free Item For Life.…

about a year ago 31:13

MP3•Episode home

This episode covers the three stages of love known as lust, attraction, and attachment. Together with my friend Alejandra, we explore how hormones like oxytocin, vasopressin, dopamine, and cortisol shape our connections and influence everything from butterflies to heartbreak. We also look at the brain’s response to emotional bonding and the evolutionary reasons behind long-term partnerships. Whether you're curious about how love works, why it hurts when it ends, or how biology fuels connection, this episode offers clear and engaging insights grounded in real research.

Science Savvy helps you understand the systems shaping your thoughts, health, and behavior. If you're ready to explore your body and brain with a little more clarity, you're in the right place.

All you need is LOVE

Science Savvy

published about a year ago

MP3•Episode home

Science Savvy helps you understand the systems shaping your thoughts, health, and behavior. If you're ready to explore your body and brain with a little more clarity, you're in the right place.

All episodes

1
Building Minds: How Architecture Shapes Our Lives and Well-Being 34:36

22 days ago34:36

34:36

Welcome to the Architecture and the Brain episode, part of Science Savvy with Carmen. In this episode, I explore how the built environment influences the way we think, feel, and connect with others. With my background in pharmacology and biomedical engineering, I break down the science behind sensory perception and neuroarchitecture, and unpack how it shows up in your daily life. This episode covers the psychology of shared spaces, the impact of natural light and materials on mood and cognition, and why we’re hardwired to respond to beauty. I’m joined by Antonio, a talented architect, as we explore how thoughtful design can support mental health, foster community, and reflect evolving cultural values. Whether you’re passionate about urban planning, curious about how light and scent influence your brain, or just want to create a more inspiring space, this episode offers clear and engaging insights grounded in real research. Science Savvy helps you understand the systems shaping your thoughts, health, and behavior. If you're ready to explore your body and brain with a little more clarity, you're in the right place. Further reading and references: Bentham, J. (1787). The Panopticon concept. Kaplan, R., & Kaplan, S. (1993). The Experience of Nature: A Psychological Perspective. Berman, M. G., Jonides, J., & Kaplan, S. (2008). The cognitive benefits of interacting with nature. Psychological Science , 19(12), 1207–1212. Galima, S. V., Vogel, S. R., & Kowalski, A. W. (2020). Seasonal affective disorder: Common questions and answers. American Family Physician , 102(11), 668–672. Pjrek, E., et al. (2020). The efficacy of light therapy in the treatment of seasonal affective disorder: A meta-analysis. Psychotherapy and Psychosomatics , 89(1), 17–24. https://doi.org/10.1159/000502891 Tao, L., et al. (2020). Light therapy in non-seasonal depression: An updated meta-analysis. Psychiatry Research , 291, 113247. https://doi.org/10.1016/j.psychres.2020.113247 Nussbaumer, B., et al. (2015). Light therapy for preventing seasonal affective disorder. Cochrane Database of Systematic Reviews , CD011269. https://doi.org/10.1002/14651858.CD011269.pub2 Do, A., et al. (2022). Blue-light therapy for seasonal and non-seasonal depression: A systematic review and meta-analysis. Canadian Journal of Psychiatry , 67(10), 745–754. https://doi.org/10.1177/07067437221097903 Rolls, E. T. (2015). Limbic systems for emotion and for memory, but no single limbic system. Cortex , 62, 119–157. https://doi.org/10.1016/j.cortex.2013.12.005 Mori, K., & Sakano, H. (2024). Circuit formation and sensory perception in the mouse olfactory system. Frontiers in Neural Circuits , 18, Article 1342576. https://doi.org/10.3389/fncir.2024.1342576 Mills, E. G. A., O'Byrne, K. T., & Comninos, A. N. (2019). Kisspeptin as a behavioral hormone. Seminars in Reproductive Medicine , 37(2), 56–63. https://doi.org/10.1055/s-0039-3400239 Gaeta, G., & Wilson, D. A. (2022). Reciprocal relationships between sleep and smell. Frontiers in Neural Circuits , 16, Article 1076354. https://doi.org/10.3389/fncir.2022.1076354 Shahsavar, P., Ghazvineh, S., & Raoufy, M. R. (2024). From nasal respiration to brain dynamic. Reviews in Neuroscience , 35(6), 639–650. https://doi.org/10.1515/revneuro-2023-0152…

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PCOS: The Reality Show Where No Egg Wins 42:33

6 weeks ago42:33

42:33

Welcome to the PCOS episode, part of Science Savvy with Carmen. In this episode, I explore the science behind Polycystic Ovarian Syndrome, a complex hormonal and metabolic condition that affects millions of women worldwide. With my background in pharmacology and biomedical engineering, I break down the mechanisms behind PCOS and unpack how it shows up in your daily life. This episode features a conversation with Dr. Basma Faris, a board-certified OB/GYN and certified culinary medicine specialist. We discuss why PCOS is not just about cystic ovaries, how insulin resistance contributes to hormonal imbalance, and the ways diet, sleep, and stress management play a role in symptom control. We also talk through the myths, the science, and the danger of wellness misinformation. Whether you're navigating a diagnosis or simply curious about how hormones, metabolism, and lifestyle connect, this episode offers clear and engaging insights grounded in real research. Science Savvy helps you understand the systems shaping your thoughts, health, and behavior. If you're ready to explore your body and brain with a little more clarity, you're in the right place. Further reading and references: St-Onge, M. P., et al. (2023). The interrelationship between sleep, diet, and glucose metabolism. Sleep Medicine Reviews , 69, 101788. https://doi.org/10.3390/medicina60010061 Ehrhardt, N., & Al Zaghal, E. (2018). Behavior modification in prediabetes and diabetes: Potential use of real-time continuous glucose monitoring. Journal of Diabetes Science and Technology , 13(2), 271–275. https://doi.org/10.1177/1932296818790994 Hanefeld, M., et al. (2014). Differences in glycemic variability between normoglycemic and prediabetic subjects. Journal of Diabetes Science and Technology , 8(2), 286–290. https://doi.org/10.1177/1932296814522739 Dmitrovic, R., et al. (2011). Continuous glucose monitoring during pregnancy in women with polycystic ovary syndrome. Obstetrics & Gynecology , 118(4), 878–885. https://doi.org/10.1097/AOG.0b013e31822c887f Tao, M., et al. (2011). Continuous glucose monitoring reveals abnormal features of postprandial glycemic excursions in women with PCOS. Postgraduate Medicine , 123(2), 185–190. https://doi.org/10.3810/pgm.2011.03.2277 Merino, J., et al. (2022). Validity of continuous glucose monitoring for categorizing glycemic responses to diet. American Journal of Clinical Nutrition , 115(6), 1569–1576. https://doi.org/10.1093/ajcn/nqac026 Wyatt, P., et al. (2021). Postprandial glycaemic dips predict appetite and energy intake in healthy individuals. Nature Metabolism , 3(4), 523–529. https://doi.org/10.1038/s42255-021-00383-x Zahalka, S. J., et al. (2024). Continuous glucose monitoring for prediabetes: What are the best metrics? Journal of Diabetes Science and Technology , 18(4), 835–846. https://doi.org/10.1177/19322968241242487 Basiri, R., & Cheskin, L. J. (2024). Personalized nutrition therapy without weight loss counseling produces weight loss in individuals with prediabetes. Nutrients , 16(14). https://doi.org/10.3390/nu16142218 Joseph, J. I., et al. (2018). Glucose sensing in the subcutaneous tissue: Correlation with immune response and CGM accuracy. Diabetes Technology & Therapeutics , 20(5), 321–324. https://doi.org/10.1089/dia.2018.0106 Jospe, M. R., et al. (2024). Leveraging continuous glucose monitoring as a catalyst for behaviour change. International Journal of Behavioral Nutrition and Physical Activity , 21(1), 74. https://doi.org/10.1186/s12966-024-01622-6 Zhu, J. P., et al. (2013). Increased mean glucose levels in patients with PCOS and hyperandrogenemia as determined by CGM. Acta Obstetricia et Gynecologica Scandinavica , 92(2), 165–171. https://doi.org/10.1111/aogs.12031 Rizos, E. C., et al. (2024). Difference on glucose profile from CGM in people with prediabetes vs. normoglycemic individuals. Journal of Diabetes Science and Technology , 18(2), 414–422. https://doi.org/10.1177/19322968221123530…

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Food for Thought: How What You Eat Shapes Your Mind, Body, and Relationships 26:37

9 weeks ago26:37

26:37

Welcome to the Food and the Brain episode, part of Science Savvy with Carmen. In this episode, I explore how the food we eat shapes not only our physical health but also our brain, behavior, and social bonds. With my background in pharmacology and biomedical engineering, I break down the science behind nutrition and neurobiology and unpack how it shows up in your daily life. This episode covers how taste, smell, and texture stimulate the brain’s reward system, the role of the gut-brain axis in mood and cognition, and how specific nutrients like omega-3s can support mental clarity. I’m joined by Pablo and Alicia, a food-loving couple who bring their own flavor to a discussion on how food influences everything from cravings and memory to connection and romance. Whether you're interested in brain health, emotional eating, or the microbiome, this episode offers clear and engaging insights grounded in real research. Science Savvy helps you understand the systems shaping your thoughts, health, and behavior. If you're ready to explore your body and brain with a little more clarity, you're in the right place. Further reading and references: Swanson, D., Block, R., & Mousa, S. A. (2012). Omega-3 fatty acids EPA and DHA: Health benefits throughout life. Advances in Nutrition , 3(1), 1–7. https://doi.org/10.3945/an.111.000893 Carabotti, M., Scirocco, A., Maselli, M. A., & Severi, C. (2015). The gut-brain axis: Interactions between enteric microbiota, central and enteric nervous systems. Annals of Gastroenterology , 28(2), 203 Yano, J. M., Yu, K., Donaldson, G. P., et al. (2015). Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis. Cell , 161(2), 264–276. https://doi.org/10.1016/j.cell.2015.02.047 Dash, S., Clarke, G., Berk, M., & Jacka, F. N. (2015). The gut microbiome and diet in psychiatry: Focus on depression. Current Opinion in Psychiatry , 28(1), 1–6 Peterson, C. T., Sharma, V., Elmen, L., & Peterson, S. N. (2015). Immune homeostasis, dysbiosis and therapeutic modulation of the gut microbiota. Clinical and Experimental Immunology , 179(3), 363–377 Calder, P. C. (2010). Omega-3 fatty acids and inflammatory processes. Nutritional Neuroscience , 13(3), 183–188 Ruddock, H. K., Brunstrom, J. M., Vartanian, L. R., & Higgs, S. (2019). A systematic review and meta-analysis of the social facilitation of eating. American Journal of Clinical Nutrition , 110(4), 842–861 Berthoud, H. R., Münzberg, H., & Morrison, C. D. (2017). Blaming the brain for obesity: Integration of hedonic and homeostatic mechanisms. Gastroenterology , 152(7), 1728–1738. https://doi.org/10.1053/j.gastro.2016.12.050 Post, M. J. (2012). Cultured meat from stem cells: Challenges and prospects. Meat Science , 92(3), 297–301 van Huis, A., Van Itterbeeck, J., Klunder, H., et al. (2013). Edible insects: Future prospects for food and feed security. FAO Forestry Paper . FAO: Rome…

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Mind over Migraine: Dehenna Davison on Battling the Invisible Pain 42:26

12 weeks ago42:26

42:26

Welcome to the Migraine episode, part of Science Savvy with Carmen. In this episode, I explore the science, stigma, and impact of migraine through the lens of lived experience and neuroscience. With my background in pharmacology and biomedical engineering, I break down the biology behind migraine and unpack how it shows up in your daily life. This episode features a conversation with Dehenna Davison, former Member of Parliament for Bishop Auckland, who made headlines when she stepped down from her dream job due to chronic migraine. Dehenna shares her journey from suffering in silence to securing the first UK parliamentary debate on migraine since the 1960s. As someone who also lives with migraine, this episode is personal and deeply meaningful. Whether you experience migraine yourself or care about someone who does, this conversation offers scientific insights and emotional validation in equal measure. Science Savvy helps you understand the systems shaping your thoughts, health, and behavior. If you're ready to explore your body and brain with a little more clarity, you're in the right place. Further reading and references: Goadsby, P. J., Holland, P. R., Martins-Oliveira, M., Hoffmann, J., Schankin, C., & Akerman, S. (2017). Pathophysiology of migraine: A disorder of sensory processing. Physiological Reviews, 97(2), 553–622. https://doi.org/10.1152/physrev.00034.2015 Burstein, R., Noseda, R., & Borsook, D. (2015). Migraine: Multiple processes, complex pathophysiology. The Journal of Neuroscience, 35(17), 6619–6629. https://doi.org/10.1523/JNEUROSCI.0373-15.2015 Charles, A. (2018). The pathophysiology of migraine: Implications for clinical management. The Lancet Neurology, 17(2), 174–182. https://doi.org/10.1016/S1474-4422(17)30435-0 World Health Organization. (2022). Headache disorders: Key facts. Retrieved from https://www.who.int/news-room/fact-sheets/detail/headache-disorders Steiner, T. J., Stovner, L. J., Jensen, R., Uluduz, D., & Katsarava, Z. (2020). Migraine remains second among the world's causes of disability, and first among young women: Findings from GBD2019. The Journal of Headache and Pain, 21(1), 137. https://doi.org/10.1186/s10194-020-01208-0 Buse, D. C., Manack, A. N., Fanning, K. M., Serrano, D., Reed, M. L., & Lipton, R. B. (2012). Chronic migraine prevalence, disability, and sociodemographic factors: Results from the American Migraine Prevalence and Prevention Study. Headache, 52(10), 1456–1470. https://doi.org/10.1111/j.1526-4610.2012.02223.x Lipton, R. B., Bigal, M. E., Diamond, M., Freitag, F., Reed, M. L., & Stewart, W. F. (2007). Migraine prevalence, disease burden, and the need for preventive therapy. Neurology, 68(5), 343–349. https://doi.org/10.1212/01.wnl.0000252808.97649.21 Prince, P. B., Rapoport, A. M., Sheftell, F. D., Tepper, S. J., & Bigal, M. E. (2004). The effect of weather on headache. Headache, 44(6), 596–602. https://doi.org/10.1111/j.1526-4610.2004.446011.x Finocchi, C., & Sivori, G. (2012). Food as trigger and aggravating factor of migraine. Neurological Sciences, 33(S1), 77–80. https://doi.org/10.1007/s10072-012-1046-5 Diener, H. C., Holle, D., Solbach, K., & Gaul, C. (2021). Medication-overuse headache: Risk factors, pathophysiology, and management. Nature Reviews Neurology, 17(2), 112–124. https://doi.org/10.1038/s41582-020-00428-0 Dodick, D. W. (2018). A phase-by-phase review of migraine pathophysiology. Headache, 58(S1), 4–16. https://doi.org/10.1111/head.13300 Silberstein, S. D., Holland, S., Freitag, F., Dodick, D. W., Argoff, C., & Ashman, E. (2012). Evidence-based guideline update: Pharmacologic treatment for episodic migraine prevention in adults. Neurology, 78(17), 1337–1345. https://doi.org/10.1212/WNL.0b013e3182535d0c Tepper, S. J., & Ashina, M. (2019). CGRP and migraine: The emerging role of CGRP inhibitors. Headache, 59(3), 394–406. https://doi.org/10.1111/head.13456 Russo, A. F. (2015). Calcitonin gene-related peptide (CGRP): A new target for migraine. Annual Review of Pharmacology and Toxicology, 55, 533–552. https://doi.org/10.1146/annurev-pharmtox-010814-124701 Lipton, R. B., Munjal, S., Alam, A., Buse, D. C., Fanning, K. M., Reed, M. L., & Schwedt, T. J. (2022). The impact of migraine on workplace productivity and the role of novel treatments. Headache, 62(3), 334–345. https://doi.org/10.1111/head.14286…

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Lasting habits I think you should build or Neuroplasticity 101 33:39

15 weeks ago33:39

33:39

Welcome to the Neuroplasticity episode, part of Science Savvy with Carmen. In this episode, I explore the incredible adaptability of the brain and what it means for learning, healing, and growth. With my background in pharmacology and biomedical engineering, I break down the science behind neuroplasticity and unpack how it shows up in your daily life. This episode covers the story of JJ, a boy who was born missing key brain structures but still outperformed his peers academically. We use his story to explore how the brain can rewire itself under extraordinary conditions and what that means for you. I also discuss the role of social interaction, sleep, oxytocin, exercise, and gut health in shaping brain function. Whether you're navigating a personal challenge, looking to boost your cognitive abilities, or simply want to understand how resilient your brain really is, this episode offers clear and engaging insights grounded in real research. Science Savvy helps you understand the systems shaping your thoughts, health, and behavior. If you're ready to explore your body and brain with a little more clarity, you're in the right place. Further reading and references: Zhao, J.-L., Jiang, W.-T., Wang, X., Cai, Z.-D., Liu, Z.-H., & Liu, G.-R. (2020). Exercise, brain plasticity, and depression. CNS Neuroscience & Therapeutics, 26(9), 885–895. https://doi.org/10.1111/cns.13395 Damiani, F., Cornuti, S., & Tognini, P. (2023). The gut-brain connection: Exploring the influence of the gut microbiota on neuroplasticity and neurodevelopmental disorders. Neuropharmacology, 109491. https://doi.org/10.1016/j.neuropharm.2023.109491 Rojczyk, A., Dziewanowska, A., & Maryniak, A. (2020). When the brain looks imperfect: An example of neuroplasticity as seen in a patient with arachnoid cysts—a case study. Frontiers in Neurology, 11, 567. https://doi.org/10.3389/fneur.2020.00567 Gulyaeva, N. V. (2017). Molecular mechanisms of neuroplasticity: An expanding universe. Biochemistry (Moscow), 82(3), 237–242. https://doi.org/10.1134/S0006297917030013 Balouch, S., Rifaat, E., Chen, H. L., & Tabet, N. (2019). Social networks and loneliness in people with Alzheimer’s dementia. International Journal of Geriatric Psychiatry, 34(5), 666–673. https://doi.org/10.1002/gps.5063 Ma, Y. H., Wang, Y. Y., Tan, L., et al. (2021). Social networks and cerebrospinal fluid biomarkers of Alzheimer’s disease. Journal of Alzheimer’s Disease, 81(1), 263–272. https://doi.org/10.3233/JAD-201202 Sachdev, P. S. (2022). Social health, social reserve, and dementia. Current Opinion in Psychiatry, 35(2), 111–117. https://doi.org/10.1097/YCO.0000000000000762 J Neurosci. (2021). Enriched environment promotes adult hippocampal neurogenesis through FGFRs. Journal of Neuroscience, 41(13), 2899–2910. https://doi.org/10.1523/JNEUROSCI.2415-20.2021 Enriched environment increases neurogenesis and improves social memory persistence in socially isolated adult mice. Journal: Unspecified. Neurobiology of Aging. (2023). Adulthood cognitive trajectories over 26 years and brain health at 70 years of age. https://doi.org/10.1016/j.neurobiolaging.2023.112386 Leuner, B., Caponiti, J. M., & Gould, E. (2012). Oxytocin stimulates hippocampal neurogenesis via oxytocin receptor expressed in CA3 pyramidal neurons. Nature Communications, 8(1), 537. https://doi.org/10.1038/s41467-017-00764-3 Sanchez-Vidaña, D. I., & Chan, A. M. (2012). Oxytocin stimulates adult neurogenesis even under conditions of stress and elevated glucocorticoids. Hippocampus, 22(4), 861–868. https://doi.org/10.1002/hipo.20942 Sleep. (2021). Adult hypothalamic neurogenesis and sleep-wake dysfunction in aging. Sleep, 44(2), zsaa173. https://doi.org/10.1093/sleep/zsaa173 Wang, L. Y., et al. (2017). Sleep and hippocampal neurogenesis: Implications for Alzheimer's disease. Frontiers in Neuroendocrinology, 45, 35–52. https://doi.org/10.1016/j.yfrne.2016.12.002 Schoch, H., et al. (2019). Memory consolidation during sleep and adult hippocampal neurogenesis. Neural Regeneration Research, 14(1), 20–23. https://doi.org/10.4103/1673-5374.243697 Koehl, M., & Abrous, D. N. (2015). Sleep and adult neurogenesis: Implications for cognition and mood. Current Topics in Behavioral Neurosciences, 25, 151–181. https://doi.org/10.1007/7854_2014_308…

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Make 2025 your b!tch: Brain hacks to build lasting habits 29:48

18 weeks ago29:48

29:48

Welcome to the New Year Habits episode, part of Science Savvy with Carmen. In this episode, I explore how to build better routines using neuroscience-backed strategies. With my background in pharmacology and biomedical engineering, I break down the science behind focus, motivation, and habit formation, and unpack how it shows up in your daily life. This episode covers how dopamine drives reinforcement, how your prefrontal cortex shapes goal setting, and how small actions can rewire your brain over time. I share five practical, research-based strategies to help you start small, reward progress, build flexibility, embrace accountability, and make decisions in advance. Whether you're trying to build healthier routines, stay off your phone, or finally stick to a New Year's resolution, this episode offers clear and actionable insights grounded in real science. Science Savvy helps you understand the systems shaping your thoughts, health, and behavior. If you're ready to explore your body and brain with a little more clarity, you're in the right place. Further reading and references: Wise, R. A., & Jordan, C. J. (2021). Dopamine, behavior, and addiction. Journal of Biomedical Science, 28(1), 83. https://doi.org/10.1186/s12929-021-00766-5 Lauretani, F., et al. (2024). Dopamine pharmacodynamics: New insights. International Journal of Molecular Sciences, 25(10), 5293. https://doi.org/10.3390/ijms25105293 Berlucchi, G., & Buchtel, H. A. (2009). Neuronal plasticity: Historical roots and evolution of meaning. Experimental Brain Research, 192(3), 307–319. https://doi.org/10.1007/s00221-008-1611-6 Talpos, J., & Shoaib, M. (2015). Executive function. Handbook of Experimental Pharmacology, 228, 191–213. https://doi.org/10.1007/978-3-319-16522-6_7…

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All you need is LOVE 31:13

19 weeks ago31:13

31:13

Welcome to the Love episode, part of Science Savvy with Carmen. In this episode, I explore the biology behind one of humanity’s most powerful emotions. With my background in pharmacology and biomedical engineering, I break down the science behind love and unpack how it shows up in your daily life. This episode covers the three stages of love known as lust, attraction, and attachment. Together with my friend Alejandra, we explore how hormones like oxytocin, vasopressin, dopamine, and cortisol shape our connections and influence everything from butterflies to heartbreak. We also look at the brain’s response to emotional bonding and the evolutionary reasons behind long-term partnerships. Whether you're curious about how love works, why it hurts when it ends, or how biology fuels connection, this episode offers clear and engaging insights grounded in real research. Science Savvy helps you understand the systems shaping your thoughts, health, and behavior. If you're ready to explore your body and brain with a little more clarity, you're in the right place. Further reading and references: Sharma, S. R., Gonda, X., Dome, P., & Tarazi, F. I. (2020). What's love got to do with it: Role of oxytocin in trauma, attachment, and resilience. Pharmacology & Therapeutics, 214, 107602. https://doi.org/10.1016/j.pharmthera.2020.107602 Fisher, H., Aron, A., & Brown, L. L. (2005). Romantic love: An fMRI study of a neural mechanism for mate choice. Journal of Comparative Neurology, 493(1), 58-62. https://doi.org/10.1002/cne.20772 Stein, D. J., & Vythilingum, B. (2009). Love and attachment: The psychobiology of social bonding. CNS Spectrums, 14(5), 239-242. https://doi.org/10.1017/s1092852900025384 Acevedo, B. P., Poulin, M. J., Collins, N. L., & Brown, L. L. (2020). After the honeymoon: Neural and genetic correlates of romantic love in newlywed marriages. Frontiers in Psychology, 11, 634. https://doi.org/10.3389/fpsyg.2020.00634…

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The Science of Friendship: Giggles, Bonding, and Learning 27:34

19 weeks ago27:34

27:34

In this episode of Science Savvy, I’m joined by my best friend of ten years, Dasha, to explore the science behind long-term friendship. With warmth, laughter, and a healthy dose of evidence-based insight, we look at how your brain syncs up with your closest companions, why oxytocin makes you feel safe and connected, and how staying close to your friends can actually support your physical health and longevity. We discuss how friendship shapes the brain, buffers stress, and even extends lifespan. Whether you're curious about how social bonds work or simply love your bestie and want to know why it matters, this episode is packed with heart and science. Science Savvy is about uncovering the biology behind the relationships, habits, and emotions that define our lives. If you're ready to understand how your friendships literally change your brain, this episode is for you. Further reading and references: Dunbar, R. I. M. (2018). Friends: Understanding the Power of Our Most Important Relationships. Little, Brown Spark. Parkinson, C., Kleinbaum, A. M., & Wheatley, T. (2018). Similar neural responses predict friendship. Nature Communications. Holt-Lunstad, J., Smith, T. B., & Layton, J. B. (2010). Social relationships and mortality risk: A meta-analytic review. PLoS Medicine. Lieberman, M. D. (2013). Social: Why Our Brains Are Wired to Connect. Crown Publishers. Cohen, S., & Wills, T. A. (1985). Stress, social support, and the buffering hypothesis. Psychological Bulletin. Lunn, N. (2021). Conversations on Love. Viking. Holt-Lunstad, J. (2018). Why social relationships are important for physical health: A systems approach to understanding and modifying risk and protection. Annual Review of Psychology. Haslam, C., & Jetten, J. (2014). Social connectedness and health in older adults. Journal of Aging and Health. Roberts, S. G., & Dunbar, R. I. (2011). Communication in social networks: Effects of kinship, network size, and emotional closeness. Personal Relationships. Langan, K. A., & Purvis, J. M. (2020). Long-distance friendship maintenance: An application of expectancy violation theory and the investment model. Current Opinion in Psychology.…

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Attention, Please: What ADHD Can Teach Us About the Brain 38:47

20 weeks ago38:47

38:47

Welcome to the ADHD episode, part of Science Savvy with Carmen. In this episode, I explore what it really means to live with ADHD and how science is reshaping the way we understand it. With my background in pharmacology and biomedical engineering, I break down the science behind attention, dopamine, and neurodiversity, and unpack how it all shows up in everyday life. This episode covers how neurotransmitters like dopamine and norepinephrine influence focus, what makes ADHD more of a difference than a deficit, and how modern life and social media interact with attention challenges. I’m joined by my brother Alex, who has ADHD, for a candid and personal conversation about medication, coping strategies, creativity, and hyperfocus. Whether you’re navigating ADHD yourself, supporting someone who is, or just curious about how attention works, this episode offers clear and engaging insights grounded in real research. Science Savvy helps you understand the systems shaping your thoughts, health, and behavior. If you're ready to explore your body and brain with a little more clarity, you're in the right place. Further reading and references: Lee, Y. C., et al. (2022). Effects of mindfulness-based interventions in children and adolescents with ADHD: A systematic review and meta-analysis of randomized controlled trials. International Journal of Environmental Research and Public Health, 19(22), 15198. https://doi.org/10.1007/s10826-011-9457-0 Arnsten, A. F. T. (2009). The emerging neurobiology of attention deficit hyperactivity disorder: The key role of the prefrontal association cortex. The Journal of Pediatrics, 154(5), I-S43. https://doi.org/10.1016/j.jpeds.2009.01.018 Volkow, N. D., & Swanson, J. M. (2013). Clinical practice: Adult attention deficit-hyperactivity disorder. The New England Journal of Medicine, 369(20), 1935-1944. https://doi.org/10.1056/NEJMcp1212625 Faraone, S. V., Biederman, J., & Mick, E. (2006). The age-dependent decline of attention deficit hyperactivity disorder: A meta-analysis of follow-up studies. Psychological Medicine, 36(2), 159-165. https://doi.org/10.1017/S003329170500471X Swanson, J. M., & Volkow, N. D. (2002). Pharmacokinetic and pharmacodynamic properties of medications for ADHD: A review of stimulant and nonstimulant formulations. Molecular Psychiatry, 8(7), 252-264. https://doi.org/10.1038/sj.mp.4001326 Keng, S. L., Smoski, M. J., & Robins, C. J. (2011). Effects of mindfulness on psychological health: A review of empirical studies. Clinical Psychology Review, 31(6), 1041-1056. https://doi.org/10.1016/j.cpr.2011.04.006 Wiklund, J., Yu, W., Tucker, R., & Marino, L. D. (2017). ADHD, impulsivity, and entrepreneurship. Journal of Business Venturing, 32(6), 627-656. https://doi.org/10.1016/j.jbusvent.2017.07.002 White, H. A., & Shah, P. (2011). Creative style and achievement in adults with attention-deficit/hyperactivity disorder. Personality and Individual Differences, 50(5), 673-677. https://doi.org/10.1016/j.paid.2010.12.015 Armstrong, T. (2010). The Power of Neurodiversity: Unleashing the Advantages of Your Differently Wired Brain. Da Capo Press. Ashinoff, B. K., & Abu-Akel, A. (2021). Hyperfocus: The forgotten frontier of attention. Psychological Research, 85, 1-19. https://doi.org/10.1007/s00426-020-01420-w…

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Wired for Wonder: Neuroscience of Creativity 30:09

22 weeks ago30:09

30:09

Welcome to the Creativity episode, part of Science Savvy with Carmen. In this episode, I explore the science behind creative thinking and how the brain fuels imagination. With my background in pharmacology and biomedical engineering, I break down the science behind creativity and unpack how it shows up in your daily life. This episode covers the roles of the prefrontal cortex and default mode network, the surprising impact of dopamine on creative flow, and how certain brain states enhance idea generation. Joined by my friend Alicia, an artist and entrepreneur with a background in psychology, we look at how both science and lived experience shape creative expression. Whether you’re an artist, a science enthusiast, or just curious about where great ideas come from, this episode offers clear and engaging insights grounded in real research. Science Savvy helps you understand the systems shaping your thoughts, health, and behavior. If you're ready to explore your body and brain with a little more clarity, you're in the right place. Further reading and references: Adnan, A., Beaty, R., Silvia, P., Spreng, R. N., & Turner, G. R. (2019). Creative aging: Functional brain networks associated with divergent thinking in older and younger adults. Neurobiology of Aging, 75, 150–158. https://doi.org/10.1016/j.neurobiolaging.2018.11.004 Kulisevsky, J., Pagonabarraga, J., & Martinez-Corral, M. (2009). Changes in artistic style and behaviour in Parkinson's disease: Dopamine and creativity. Journal of Neurology, 256(5), 816–819. https://doi.org/10.1007/s00415-009-5001-1 Weinberger, A. B., Green, A. E., & Chrysikou, E. G. (2017). Using transcranial direct current stimulation to enhance creative cognition: Interactions between task, polarity, and stimulation site. Frontiers in Human Neuroscience, 11, 246. https://doi.org/10.3389/fnhum.2017.00246 Chi, R. P., & Snyder, A. W. (2012). Brain stimulation enables the solution of an inherently difficult problem. Neuroscience Letters, 515(2), 121–124. https://doi.org/10.1016/j.neulet.2012.03.012…

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You Are What You Eat: The Gut Microbiome Shapes Mood, Health, and Behavior 33:41

24 weeks ago33:41

33:41

Welcome to the Gut Health episode, part of Science Savvy with Carmen. In this episode, I explore how your gut microbiome does so much more than support digestion. With my background in pharmacology and biomedical engineering, I break down the science behind the gut-brain connection and unpack how it shows up in your daily life. This episode covers how gut bacteria influence your mood, mental health, immune function, and even decision-making. I share fascinating research on the relationship between the microbiome and depression, explain the biological pathways linking your gut to your brain, and offer practical tips for improving gut health through diet and lifestyle. Whether you're curious about probiotics, interested in the science of mood, or simply want to understand your body better, this episode offers clear and engaging insights grounded in real research. Science Savvy helps you understand the systems shaping your thoughts, health, and behavior. If you're ready to explore your body and brain with a little more clarity, you're in the right place. Further reading and references: Bercik, P., & Collins, S. M. (2014). The effects of the microbiota on the central nervous system and behavioral disorders. Gastroenterology, 146(6), 1449-1458. https://doi.org/10.1053/j.gastro.2014.02.037 Cryan, J. F., & Dinan, T. G. (2012). Mind-altering microorganisms: The impact of the gut microbiota on brain and behaviour. Nature Reviews Neuroscience, 13(10), 701-712. https://doi.org/10.1038/nrn3346 Foster, J. A., Rinaman, L., & Cryan, J. F. (2017). Stress and the gut-brain axis: Regulation by the microbiome. Neurobiology of Stress, 7, 124-136. https://doi.org/10.1016/j.ynstr.2017.03.001 Mayer, E. A., Padua, D., & Tillisch, K. (2014). Altered brain-gut axis in autism: Comorbidity or causative mechanisms. BioEssays, 36(10), 933-939. https://doi.org/10.1002/bies.201400075 Clarke, G., Stilling, R. M., Kennedy, P. J., Stanton, C., Cryan, J. F., & Dinan, T. G. (2014). Minireview: Gut microbiota: The neglected endocrine organ. Molecular Endocrinology, 28(8), 1221-1238. https://doi.org/10.1210/me.2014-1108 Sampson, T. R., & Mazmanian, S. K. (2015). Control of brain development, function, and behavior by the microbiome. Cell Host & Microbe, 17(5), 565-576. https://doi.org/10.1016/j.chom.2015.04.011 O'Mahony, S. M., Clarke, G., Dinan, T. G., & Cryan, J. F. (2015). Early-life adversity and brain development: Is the microbiome a missing piece of the puzzle. Neuroscience, 342, 37-54. https://doi.org/10.1016/j.neuroscience.2015.09.068 Ridaura, V. K., et al. (2013). Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science, 341(6150), 1241214. https://doi.org/10.1126/science.1241214 Dash, S., Clarke, G., Berk, M., & Jacka, F. N. (2015). The gut microbiome and diet in psychiatry: Focus on depression. Current Opinion in Psychiatry, 28(1), 1-6. https://doi.org/10.1097/YCO.0000000000000117 Madra, M., & Ringel, Y. (2015). The role of probiotics in treating irritable bowel syndrome. Gastroenterology Clinics of North America, 44(1), 159-175. https://doi.org/10.1016/j.gtc.2014.11.013 Jacka, F. N., et al. (2017). A randomized controlled trial of dietary improvement for adults with major depression (the SMILES trial). BMC Medicine, 15, 23. https://doi.org/10.1186/s12916-017-0791-y Staudacher, H. M., et al. (2017). Probiotic and prebiotic mechanisms to improve mental health via the gut-brain axis. Current Opinion in Pharmacology, 38, 69-77. https://doi.org/10.1016/j.coph.2018.03.008 Kong, X., et al. (2020). Probiotics supplementation during antibiotic treatment reduces the risk of Clostridium difficile-associated diarrhea. The American Journal of Gastroenterology, 115(6), 921-929. https://doi.org/10.14309/ajg.0000000000000601 Mills, J. P., et al. (2017). The impact of cesarean delivery on the diversity of the infant gut microbiome. Microbial Ecology in Health & Disease, 28(1), 13777. https://doi.org/10.1080/16512235.2017.13777…

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Who the F*!k am I? Science of Consciousness & Self-Awareness 26:57

26 weeks ago26:57

26:57

Welcome to the Consciousness episode, part of Science Savvy with Carmen. In this episode, I explore what it really means to be conscious and how self-awareness shapes who we are. With my background in pharmacology and biomedical engineering, I break down the science behind consciousness and unpack how it shows up in your daily life. This episode covers everything from classic philosophical ideas like Descartes’ “I think, therefore I am” to modern neuroscience frameworks such as Crick’s Astonishing Hypothesis and Tononi’s information integration theory. We explore how brain chemistry, genetics, and personal experience come together to influence identity, self-esteem, and the feeling of being a self at all. Whether you’re curious about how the brain creates your sense of self or interested in the science behind awareness and emotion, this episode offers clear and engaging insights grounded in real research. Science Savvy helps you understand the systems shaping your thoughts, health, and behavior. If you're ready to explore your body and brain with a little more clarity, you're in the right place. Further reading and references: Crick, F. (1994). The Astonishing Hypothesis: The Scientific Search for the Soul. Scribner. Chalmers, D. J. (1995). Facing up to the problem of consciousness. Journal of Consciousness Studies, 2(3), 200-219. Tononi, G. (2004). An information integration theory of consciousness. BMC Neuroscience, 5(42). Koch, C., Massimini, M., Boly, M., & Tononi, G. (2016). Neural correlates of consciousness: progress and problems. Nature Reviews Neuroscience, 17(5), 307-321. Northoff, G., Heinzel, A., de Greck, M., Bermpohl, F., Dobrowolny, H., & Panksepp, J. (2006). Self-referential processing in our brain. NeuroImage, 31(1), 440-457. Lieberman, M. D., & Eisenberger, N. I. (2009). Pains and pleasures of social life. Science, 323(5916), 890-891. Panksepp, J. (1998). Affective Neuroscience: The Foundations of Human and Animal Emotions. Oxford University Press.…

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[Interview tester] All you need is LOVE 32:03

28 weeks ago32:03

32:03

This is one of our early interview episodes. We shared a microphone and the audio is a bit raw, so feel free to check out our latest episodes for a more polished experience. Welcome to the Love episode, part of Science Savvy with Carmen. In this episode, I explore the biology behind one of humanity’s most powerful emotions. With my background in pharmacology and biomedical engineering, I break down the science behind love and unpack how it shows up in your daily life. This episode covers the three stages of love known as lust, attraction, and attachment. Together with my friend Alejandra, we explore how hormones like oxytocin, vasopressin, dopamine, and cortisol shape our connections and influence everything from butterflies to heartbreak. We also look at the brain’s response to emotional bonding and the evolutionary reasons behind long-term partnerships. Whether you're curious about how love works, why it hurts when it ends, or how biology fuels connection, this episode offers clear and engaging insights grounded in real research. Science Savvy helps you understand the systems shaping your thoughts, health, and behavior. If you're ready to explore your body and brain with a little more clarity, you're in the right place. Further reading and references: Sharma, S. R., Gonda, X., Dome, P., & Tarazi, F. I. (2020). What's love got to do with it: Role of oxytocin in trauma, attachment, and resilience. Pharmacology & Therapeutics, 214, 107602. https://doi.org/10.1016/j.pharmthera.2020.107602 Fisher, H., Aron, A., & Brown, L. L. (2005). Romantic love: An fMRI study of a neural mechanism for mate choice. Journal of Comparative Neurology, 493(1), 58-62. https://doi.org/10.1002/cne.20772 Stein, D. J., & Vythilingum, B. (2009). Love and attachment: The psychobiology of social bonding. CNS Spectrums, 14(5), 239-242. https://doi.org/10.1017/s1092852900025384 Acevedo, B. P., Poulin, M. J., Collins, N. L., & Brown, L. L. (2020). After the honeymoon: Neural and genetic correlates of romantic love in newlywed marriages. Frontiers in Psychology, 11, 634. https://doi.org/10.3389/fpsyg.2020.00634…

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Periods - Why Can’t Mother Nature Just Text Me I'm Not Pregnant? 19:56

30 weeks ago19:56

19:56

In this episode of Science Savvy, we tackle one of the most common yet least understood experiences in women’s health: why do we get periods. From evolutionary theories to hormonal rollercoasters, I explore the biology and history behind menstruation and the science that underlies symptoms like bloating, mood swings, and acne. With my background in pharmacology and biomedical engineering, I break down why periods exist in the first place and what they can reveal about your health. We look at the theories around menstruation as a defense mechanism, the evolution of concealed ovulation, and how different phases of the cycle impact your brain, energy levels, and even your creativity. Whether you’re curious about how your body works or want to better align your lifestyle with your cycle, this episode offers practical insights grounded in biology and evolutionary science. Science Savvy is here to help you understand your body and brain through a scientific lens. If you’re ready to work with your cycle instead of against it, this episode is for you. Further reading and references: Profet, M. (1993). Menstruation as a defense against pathogens transported by sperm. The Quarterly Review of Biology, 68(3), 335-386. Strassmann, B. I. (1996). The evolution of endometrial cycles and menstruation. The Quarterly Review of Biology, 71(2), 181-220. Pawlowski, B. (1999). Loss of oestrus and concealed ovulation in human evolution: The case against the sexual-selection hypothesis. Current Anthropology, 40(3), 257-275. Emera, D., Romero, R., & Wagner, G. (2012). The evolution of menstruation: A new model for genetic assimilation. BioEssays, 34(1), 26-35. Hillard, P. J. A., & Speroff, L. (2019). Clinical Gynecologic Endocrinology and Infertility. Wolters Kluwer Health. Miller, G., Tybur, J. M., & Jordan, B. D. (2007). Ovulatory cycle effects on tip earnings by lap dancers: Economic evidence for human estrus. Evolution and Human Behavior, 28(6), 375-381. Haselton, M. G., & Gildersleeve, K. (2011). Can men detect ovulation. Current Directions in Psychological Science, 20(2), 87-92. Johnson, S., Marriott, L., & Zinaman, M. (2018). Accuracy of an online fertility tracker. Journal of Women's Health, 27(4), 435-442. Wilcox, A. J., Weinberg, C. R., & Baird, D. D. (1995). Timing of sexual intercourse in relation to ovulation. The New England Journal of Medicine, 333(23), 1517-1521. Yang, Z., & Schank, J. C. (2006). Women do not synchronize their menstrual cycles. Human Nature, 17(4), 433-447. Frank-Herrmann, P., et al. (2007). The effectiveness of a fertility awareness-based method to avoid pregnancy in relation to a couple's sexual behavior during the fertile time. Human Reproduction, 22(5), 1310-1319. Berglund Scherwitzl, E., et al. (2017). Fertility awareness-based mobile application for contraception. The European Journal of Contraception & Reproductive Health Care, 22(5), 365-373.…

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[Interview tester] The Science of Friendship: Giggles, Bonding, and Learning 21:15

31 weeks ago21:15

21:15

This is one of our early interview episodes. We shared a microphone and I hadn't yet perfected my audio editing, so feel free to check out our latest episodes for a more polished experience. In this episode of Science Savvy, I’m joined by my best friend of ten years, Dasha, to explore the science behind long-term friendship. With warmth, laughter, and a healthy dose of evidence-based insight, we look at how your brain syncs up with your closest companions, why oxytocin makes you feel safe and connected, and how staying close to your friends can actually support your physical health and longevity. We discuss how friendship shapes the brain, buffers stress, and even extends lifespan. Whether you're curious about how social bonds work or simply love your bestie and want to know why it matters, this episode is packed with heart and science. Science Savvy is about uncovering the biology behind the relationships, habits, and emotions that define our lives. If you're ready to understand how your friendships literally change your brain, this episode is for you. Further reading and references: Dunbar, R. I. M. (2018). Friends: Understanding the Power of Our Most Important Relationships. Little, Brown Spark. Parkinson, C., Kleinbaum, A. M., & Wheatley, T. (2018). Similar neural responses predict friendship. Nature Communications. Holt-Lunstad, J., Smith, T. B., & Layton, J. B. (2010). Social relationships and mortality risk: A meta-analytic review. PLoS Medicine. Lieberman, M. D. (2013). Social: Why Our Brains Are Wired to Connect. Crown Publishers. Cohen, S., & Wills, T. A. (1985). Stress, social support, and the buffering hypothesis. Psychological Bulletin. Lunn, N. (2021). Conversations on Love. Viking. Holt-Lunstad, J. (2018). Why social relationships are important for physical health: A systems approach to understanding and modifying risk and protection. Annual Review of Psychology. Haslam, C., & Jetten, J. (2014). Social connectedness and health in older adults. Journal of Aging and Health. Roberts, S. G., & Dunbar, R. I. (2011). Communication in social networks: Effects of kinship, network size, and emotional closeness. Personal Relationships. Langan, K. A., & Purvis, J. M. (2020). Long-distance friendship maintenance: An application of expectancy violation theory and the investment model. Current Opinion in Psychology.…

Science Savvy

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[Pilot] How Our Brains Predict and Shape Everyday Life 24:46

32 weeks ago24:46