Deep in the back of your mind, you’ve always had the feeling that there’s something strange about reality. There is. Join Robert Lamb and Joe McCormick as they examine neurological quandaries, cosmic mysteries, evolutionary marvels and our transhuman future.
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Similar to The Science of Everything Podcast
If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.
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Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
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Episode 152: Obesity, Diabetes, and Hypertension
Manage episode 474085501 series 2360076
Content provided by James Fodor. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by James Fodor or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
A review of the science between the metabolic syndrome, including discussion of obesity, diabetes, hypertension, and hyperlipidemia. We discuss the pathophysiology of how enlargement of adipocytes disrupts metabolic signalling pathways and leads to buildup of lipid intermediates. We then consider how these effects impair health, examining the causes of insulin resistance, atherosclerosis, and dysregulation of blood pressure. We conclude by looking at how such symptoms lead to pathology and increased mortality in overweight and obese individuals. Recommended prelistening is Episode 151: Diet and Nutrition, and Episode 18: Biochemistry Basics.
If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter.
178 episodes
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Manage episode 474085501 series 2360076
Content provided by James Fodor. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by James Fodor or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://player.fm/legal.
A review of the science between the metabolic syndrome, including discussion of obesity, diabetes, hypertension, and hyperlipidemia. We discuss the pathophysiology of how enlargement of adipocytes disrupts metabolic signalling pathways and leads to buildup of lipid intermediates. We then consider how these effects impair health, examining the causes of insulin resistance, atherosclerosis, and dysregulation of blood pressure. We conclude by looking at how such symptoms lead to pathology and increased mortality in overweight and obese individuals. Recommended prelistening is Episode 151: Diet and Nutrition, and Episode 18: Biochemistry Basics.
If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter.
178 episodes
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The Science of Everything Podcast
1 Special Episode: Brain Preservation and Abolishing Death 1:16:05
1:16:05 
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Play Later Play Later Lists Like LikedAn interview with Ariel Zeleznikow-Johnston, author of the book 'The Future Loves You: How and Why We Should Abolish Death'. We begin by discussing how best to define death, focusing on the idea of death as the permanent disruption of psychological identity, and how such identity is constituted by our personality, desires, and memories. We then consider the science of brain preservation, including the recently-developed technique of Aldehyde-Stabilized Cryopreservation, and how it could be used to indefinitely preserve the brain structure that encodes or personal identity. Ariel argues that such a preserved brain could potentially be used to construct a digital simulation of our brains, essentially allowing us to survive the biological death of our bodies. We conclude by considering some potential challenges of implementign such a technology, and whether it would achieve widespread social acceptance. Ariel's book: The Future Loves You: How and Why We Should Abolish Death Turning Fate into Choice: Patient Self-Determination and Life Extension More on brain preservation: A case for developing Aldehyde Stabilized Cryopreservation into a medical procedure How much protein structure loss is there following glutaraldehyde crosslinking? Large Mammal BPF Prize Winning Announcement Mapping the Drosophila brain: The connectome of an insect brain | Science…
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The Science of Everything Podcast
1 Episode 152: Obesity, Diabetes, and Hypertension 1:16:34
1:16:34 Play Later Play Later Lists Like Liked1:16:34
Play Later Play Later Lists Like LikedA review of the science between the metabolic syndrome, including discussion of obesity, diabetes, hypertension, and hyperlipidemia. We discuss the pathophysiology of how enlargement of adipocytes disrupts metabolic signalling pathways and leads to buildup of lipid intermediates. We then consider how these effects impair health, examining the causes of insulin resistance, atherosclerosis, and dysregulation of blood pressure. We conclude by looking at how such symptoms lead to pathology and increased mortality in overweight and obese individuals. Recommended prelistening is Episode 151: Diet and Nutrition, and Episode 18: Biochemistry Basics. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything…
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The Science of Everything Podcast
An introduction to human nutrition, in which we discuss the nutritional importance and role of carbohydrates, fats, proteins, vitamins, and minerals, before considering the effects of malnutrition, how it is measured, and its prevalence around the world. We conclude with an analysis of basal metabolic rate, reviewing evidence concerning its variability across persons and factors that affect it. Recommended pre-listening is Episode 18: Biochemistry Basics If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything…
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The Science of Everything Podcast
1 Episode 150: How Home Appliances Work 1:17:11
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Play Later Play Later Lists Like LikedAn exploration into the exciting world of home appliances and devices. We begin with a journey through the kitchen, discussing the design and operating principles behind the refrigerator, rice cooker, convection oven, microwave, and dishwasher. We proceed to the laundry to examine how the washing machine, vacuum cleaner, clothes iron, and dryer work. Finally we take a bathroom break and consider how the flush toilet, sinks, and plumbing work. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything…
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The Science of Everything Podcast
An introduction to the psychological study of personality, beginning with a definition of what is and is not personality and a brief history of the development of the field from Freud and Jung through the Myers-Briggs Indicator and the modern trait theories. I then discuss the Big Five personality traits, covering openness, conscientiousness, extraversion, agreeableness, and neuroticism, along with validation and criticisms of this model. I conclude with a brief discussion of values and narrative identity as additional aspects of personality. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything…
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The Science of Everything Podcast
1 Episode 148: Control of Gene Expression 1:09:05
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Play Later Play Later Lists Like LikedAn introduction to the processes by which cells control which genes are expressed. We begin with an overview of why genetic regulation is necessary and the key stages where such regulation occurs, including key concepts such as transcription factors and DNA binding domains. We then discuss prokaryotic gene regulation, focusing on the lac operon in E. coli. We then expand the discussion to cover the various mechanisms of eukaryotic gene regulation, including chromatic remodelling, transcriptional regulation, post-transcriptional regulation, RNA editing, and micro RNAs. Recommended pre-listening is Episodes 34-35: DNA Structure and Function, and Episode 118: Cell Signalling. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything…
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The Science of Everything Podcast
1 Episode 147: Genetic Mutation and Repair 1:13:51
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Play Later Play Later Lists Like LikedHere we survey of the causes and consequences of genetic mutation, including a discussion of mechanisms of endogenous and induced mutations, rates of mutation, types of single nucleotide mutations, and the phenotypic effects of mutation. We also discuss various mechanisms for detecting and repairing genetic mutations, including base excision repair, DNA mismatch repair, nucleotide excision repair, double strand break repair. We conclude with an examination of large-scale chromosomal changes, including deletions, duplications, inversions, and translocations, unequal crossing over, with a brief look at polypoidy in plants and aneuploidy in humans. Recommended pre-listening is Episodes 34 and 35: DNA Structure and Function, and Episode 44: Cell Division. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything…
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The Science of Everything Podcast
1 Episode 146: Mendelian Genetics and Inheritance 1:22:34
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Play Later Play Later Lists Like LikedAn introduction to classical Mendelian genetics, in which we discuss Mendel's experiments with peas and the laws of heredity that he discovered, including inheritance of one allele from each parent, the law of dominance, and the law of independent segregation. We then consider more complex cases of genetic inheritance, including sex-linked traits, incomplete dominance, codominance, and epistasis. The episode concludes with a discussion of quantitative traits determined by many genes, including how genetic variation is described, how sources of variance are identified using genome wide association studies, and the conceptual issues with defining heredity and separating the effects of genes from those of environment. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything Check out out youtube channel! The Science of Everything Podcast - YouTube…
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The Science of Everything Podcast
1 Episode 145: Relativity and Black Holes 1:25:43
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Play Later Play Later Lists Like LikedContinuing our series on General Relativity, we discuss the derivation of the Schwarzschild metric as a vacuum solution to Einstein's Field Equations, and analyse the physical meaning of this solution, including the properties of the singularity, event horizon, and effects of time dilation and length compression. We then consider how solutions like the Schwarzschild metric yield testable predictions such as gravitational lensing and graviational redshift, which serve as important evidence in support of General Relativity. We conclude with a discussion about some of the more exotic aspects of black holes, including Hawking radiation, the no hair theorem, and the black hole information loss paradox. Recommended pre-listening is Episode 136: Introduction to General Relativity. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything…
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The Science of Everything Podcast
1 Episode 144: Anthropogenic Climate Change 1:18:48
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Play Later Play Later Lists Like LikedOur climate change series concludes with a discussion of the various lines of evidence indicating that recent warming is the result of human-produced greenhouse gases, including greater warming at night, cooling of the stratosphere, and relative depletion of C14 in the atmosphere. We then consider the various expected impacts of climate change, including increased extreme weather events, acidification of the oceans, changes to crop yields, and affects on various ecosystems. We end with an analysis of the relative costs and benefits of mitigation, and discuss likjely climate projections for the remainder of the 21st century. Recommended pre-listening is Episode 143: Climate Modelling. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything Check out out youtube channel! The Science of Everything Podcast - YouTube…
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The Science of Everything Podcast
An overview of climate models, beginning with a summary of the major types of models, and then a more detailed disussion of hte primitive equations and parameterised feedbacks that characterise the widely used Atmospheric General Circulation Models. We also discuss techniques for model validation and some evidence regarding the accuracy of various climate models. Recommended pre-listening is Episode 142: The Greenhouse Effect. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything Check out out youtube channel! The Science of Everything Podcast - YouTube…
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The Science of Everything Podcast
A detailed discussion of the greenhouse effect and its impact on Earth's climate. We begin with a discussion of Earth’s energy budget, the various greenhouse gases and their interactions with longwave radiation, and a summary of major sources of greenhouse gas emisions. We then examine the mechanisms of the greenhouse effect in more detail using the idealised greenhouse model and radiative transfer models. We conclude with an analysis of the sensitivity of Earth's climate to changes in greenhouse gas concentrations, and how this interacts with the atmospheric lapse rate. Recommended prelistening is Episode 141: Natural Climate Change. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything…
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The Science of Everything Podcast
An overview of the natural mechanisms by which climate changes over time. Beginning with an introduction to the concepts of radiative forcing and climate sensitivity, we then discuss solar forcing, orbital changes, volcanic eruptions, and silicate weathering, covering how each process operates and the effects it has on Earth's climate over varying periods of time. Recommended pre-listening is Episode 140: A History of Earth's Climate. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything…
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The Science of Everything Podcast
A journey through the history of Earth's changing climate, in which we explore how Earth's climate has fluctuated over the past billion years. After reviewing the various temperature proxies used to estimate past climactic conditions, we discuss the varying hothouse and icehouse periods of Earth's history, the onset of the Quarternay Ice Age, the current interglacial period, the anomoly of the Younger Dryas, the Medieval Warm Period and Little Ice Ages, and the rapid rise in temperatures during the twentieth century. Recommended pre-listening is Episode 90: Climate Systems. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything…
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The Science of Everything Podcast
1 Special Episode: Dinosaurs in Popular Culture 1:13:20
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Play Later Play Later Lists Like LikedIn this special collaboration with I Know Dino podcast, we discuss the history and impact of dinosaurs in popular culture and media. We cover the history of the scientific study of dinosaurs and how their presentation in media has changed over time with new discoveries, and what aspects of their behaviour and appearance tend to be presented accuracy or inaccurately. We also discuss lesser-known aspects of understanding dinosaurs, such as how changes in the atmosphere and ecosystem would affect dinosaurs of they were to be alive today. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything…
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Similar to The Science of Everything Podcast
Deep in the back of your mind, you’ve always had the feeling that there’s something strange about reality. There is. Join Robert Lamb and Joe McCormick as they examine neurological quandaries, cosmic mysteries, evolutionary marvels and our transhuman future.
…
continue reading
If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.
…
continue reading
Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
…
continue reading
Unseeable forces control human behavior and shape our ideas, beliefs, and assumptions. Invisibilia—Latin for invisible things—fuses narrative storytelling with science that will make you see your own life differently.
…
continue reading
Interviews with Anthropologists about their New Books Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/anthropology
…
continue reading
The Science Show gives Australians unique insights into the latest scientific research and debate, from the physics of cricket to prime ministerial biorhythms.
…
continue reading
Come dive into one of the curiously delightful conversations overheard at National Geographic’s headquarters, as we follow explorers, photographers, and scientists to the edges of our big, weird, beautiful world. Hosted by Peter Gwin and Amy Briggs.
…
continue reading
The kickass science and technology radio show that delivers an irreverent look at the week in science and technology.
…
continue reading
Whether the topic is popcorn or particle physics, you can count on BrainStuff to explore -- and explain -- the everyday science in the world around us.
…
continue reading
A myriad of AI, science, and technology experts explore the real challenges and enormous opportunities facing entrepreneurs who are building the future of health. Raising Health, a podcast by a16z Bio + Health and hosted by Kris Tatiossian and Olivia Webb, dives deep into the heart of biotechnology and healthcare innovation. Join veteran company builders, operators, and investors Vijay Pande, Julie Yoo, Vineeta Agarwala, and Jorge Conde, along with distinguished guests like Mark Cuban, Greg ...
…
continue reading
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