02_06 HER-2 Low Breast Cancer and Sacutuzumab Govetecan

Talking About Tumors with Ryann and Ryan - A medical oncology podcast

1. HER-2 Testing Algorithm
2. Trastuzumab Deruxtecan in HER-2 Low MBC
3. 2:1 Randomization, Treatment of Provider Choice
4. Sacutuzumab Govetacan for later line TNBC and HR positive MBC

Citations

As always, citations, and sources include education from our respective training programs, the Devita textbook, and Uptodate.com. We highly encourage review of guidelines published by ASCO, ESMO and other organizations local to your practice.

DeVita, Vincent T., Jr., Theodore S. Lawrence, and Steven A. Rosenberg. Devita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology. 10th edition. Philadelphia: Wolters Kluwer, 2015.

Uptodate.com Waltham, MA: Wolters Kluwer.

Some highlighted references recommended to read related to this specific episode:

1.Wolff A et al. JCO. 2018;36(20):2105-2122. doi:10.1200/JCO.2018.77.8738

2.Modi S et al. NEJM. 2022;387(1):9-20. doi:10.1056/NEJMOA2203690/

3.BardiaI A et al. NEJM. 2021;384:1529-1541. doi:10.1056/NEJMOA2028485

4.Rugo H et al. JCO. Published online Aug 26, 2022 . doi:10.1200/JCO.22.01002

5.Rugo H et al. Ann Oncol. 2022;33(suppl_7):S808-S869. doi:10.1016/annonc/annonc1089

Disclosures

Talking about Tumors with Ryan and Ryann is not medical advice. We have received no funding in relation to the information discussed within this episode and have no financial conflicts of interest to disclose. All opinions are those of whoever stated them. We have compiled this podcast to serve as an introduction to the field of medical oncology for post-graduate trainees interested in the topic.

Tags

Hematology/Oncology, evidence based medicine, education, chemotherapy, immunotherapy, medical oncology

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