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Dr Carla Mazzeo: The Exosome Queen
Manage episode 341812673 series 3002507
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Dr Carla Mazzeo is a biochemist based in Boston who has 15 years experience with research on exosomes. This research has real world applications in treating cancer, irritable bowel syndrome, Crohn's Disease, pain & inflammation, and regenerative medicine.
Exosomes are a class of cell-derived extracellular vesicles of endosomal origin, and are typically 30-150 nm in diameter – the smallest type of extracellular vesicle.1 Enveloped by a lipid bilayer, exosomes are released into the extracellular environment containing a complex cargo of contents derived from the original cell, including proteins, lipids, mRNA, miRNA and DNA.2 Exosomes are defined by how they are formed – through the fusion and exocytosis of multivesicular bodies into the extracellular space. (from TechnologyNetworks.com
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